M. Nair

发表

An in vitro study reveals the anti-obesity effects of 7- methoxy-3-methyl-5-((E)-prop-1-enyl)-2-(3,4,5-trimethoxyphenyl)-2,3-dihydrobenzofuran from Myristica fragrans.

K. Raghu, G. L. Shyni, Sajin K Francis, 2020, European journal of pharmacology.

APOPTOSIS MEDIATED CYTOTOXICITY INDUCED BY ISODEOXYELEPHANTOPIN ON NASOPHARYNGEAL CARCINOMA CELLS

M. Nair, K. Farhaa, S. GeethaB., 2013 .

Licarin B from Myristica fragrans improves insulin sensitivity via PPARγ and activation of GLUT4 in the IRS-1/PI3K/AKT pathway in 3T3-L1 adipocytes

K. Raghu, G. L. Shyni, Sajin K Francis, 2016 .

Epoxyazadiradione exhibit activities in head and neck squamous cell carcinoma by targeting multiple pathways

Subash C. Gupta, Satya N. Das, S. Aggarwal, 2020, Apoptosis : an international journal on programmed cell death.

Synthesis of novel highly functionalized biologically active polycyclic caged amides

M. Nair, S. Viji, D. Lakshmanan, 2007 .

Anticancer activity studies of cubebin isolated from Piper cubeba and its synthetic derivatives.

S. Varughese, M. Nair, Nisha Prakasan, 2016, Bioorganic & medicinal chemistry letters.

Anti-hyperlipidemic potential of natural product based labdane-pyrroles via inhibition of cholesterol and triglycerides synthesis.

Sasidhar B. Somappa, M. Nair, Sangeetha Mohan, 2021, Bioorganic chemistry.

Flavonoids and other constituents from the rhizomes of Alpinia calcarata.

M. Nair, P. Hema, 2009 .

Efficient enzymatic kinetic resolution of 4-hydroxytetralone and 3-hydroxyindanone

M. Nair, S. Joly, 2001 .

Isodeoxyelephantopin from Elephantopus scaber (Didancao) induces cell cycle arrest and caspase-3-mediated apoptosis in breast carcinoma T47D cells and lung carcinoma A549 cells

D. Rajalekshmi, M. Nair, F. A. Kabeer, 2014, Chinese Medicine.

Chemical constituents from Chonemorpha fragrans roots and antibacterial activity studies of sarcorucinine D

M. Nair, V. Sankar, B. S. Dileep Kumar, 2021, Natural product research.

Pinocembrin triggers Bax‐dependent mitochondrial apoptosis in colon cancer cells

T. Santhoshkumar, John Mohan, M. Nair, 2007, Molecular carcinogenesis.

Phytochemical constituents of Curcuma amada

M. Nair, D. Sheeja, D. B. A. Sheeja, 2012 .

Antineoplastic effects of deoxyelephantopin, a sesquiterpene lactone from Elephantopus scaber, on lung adenocarcinoma (A549) cells.

M. Nair, D. S. Rajalekshmi, F. A. Kabeer, 2013, Journal of integrative medicine.

Formation of highly caged compounds through Diels-Alder cycloaddition of 3-bromo-7-(bromomethyl)tetracyclo[5.3.1.02,6.04,8]undeca-10(12)-ene-9,11-dione with itself and with cyclopentadiene

M. Nair, N. Rath, S. Joly, 2004 .

In vitro and in vivo antitumor activity of deoxyelephantopin from a potential medicinal plant Elephantopus scaber against Ehrlich ascites carcinoma

M. Nair, D. S. Rajalekshmi, F. A. Kabeer, 2019, Biocatalysis and Agricultural Biotechnology.

Isolation and Identification of α-Glucosidase and Protein Glycation Inhibitors from Stereospermum colais

K. Raghu, M. Nair, K. Padmakumari, 2014, Applied Biochemistry and Biotechnology.

Phytochemical investigation on Myristica fragrans stem bark

S. Varughese, Sajin K Francis, M. Nair, 2019, Natural product research.

Metal‐Free trans‐Aziridination of Zerumbone: Synthesis and Biological Evaluation of Aziridine Derivatives of Zerumbone

Greeshma Gopalan, K. Radhakrishnan, M. Nair, 2017 .

Crotepoxide Chemosensitizes Tumor Cells through Inhibition of Expression of Proliferation, Invasion, and Angiogenic Proteins Linked to Proinflammatory Pathway*

B. Aggarwal, S. Prasad, M. Chaturvedi, 2010, The Journal of Biological Chemistry.

Friedel–Crafts alkylation of a cage enone: synthesis of aralkyl substituted tetracyclo[5.3.1.0[2,6].0[4,8]]undeca-9,11-diones and the formation of fascinating novel cage compounds with pyrrole and thiophene using Montmorillonite K-10

E. Suresh, M. Nair, B. James, 2007 .

The dioxanone-to-dihydropyran Claisen rearrangement. Synthesis of C(7)-C(13) fragments of erythronolides A and B

F. Schoenen, M. Nair, S. D. Burke, 1987 .

Synthesis of spheroidal C20-polyquinanes in a route towards dodecahedrane

K. R. Reddy, G. Mehta, M. Nair, 1991 .

Lipase catalyzed kinetic resolution of aryl β-hydroxy ketones

M. Nair, S. Joly, 2000 .

Decipic acid and 12-acetyl apetalic acid from Calophyllum decipiens. Wight

M. Nair, G. Jayakumar, M. D. Ajithabai, 2012 .

Friedel—Crafts Alkylation of a Cage Enone: Synthesis of Aralkyl Substituted Tetracyclo[5.3.1.0[2,6].0[4,8]]undeca-9,11-diones and the Formation of Fascinating Novel Cage Compounds with Pyrrole and Thiophene Using Montmorillonite K-10.

E. Suresh, M. Nair, B. James, 2007 .

Two fascinating rearrangements through selective placement of bromine substituents. Photochemical synthesis of 3-bromo-7-(bromomethyl) tetracyclo[5.3.1.02,6.04,8]undec-10(12)-ene-9,11-dione and its rearrangement with amines

M. Nair, N. Rath, S. Joly, 1999 .

Discovery of Natural Product Derived Labdane Appended Triazoles as Potent Pancreatic Lipase Inhibitors.

Sasidhar B. Somappa, M. Nair, K. T. Ashitha, 2018, ACS medicinal chemistry letters.

A novel, versatile synthetic approach to linearly fused tricyclopentanoids via photo-thermal olefin metathesis

G. Mehta, M. Nair, A. Srikrishna, 1981 .

Chemical constituents from Myristica fragrans fruit

E. Suresh, M. Nair, K. S. Francis, 2014, Natural product research.

Natural Product Research: Formerly Natural Product Letters

E. Suresh, M. Nair, W. Mahabusarakam, 2014 .

Analogues of the Quararibea metabolite chiral enolic-γ-lactone from (2S,3S)- and (2S,3R)-tetrahydro-3-hydroxy-5-oxo-2,3-furandicarboxylic acids

M. Nair, I. Ibnusaud, C. Gopinath, 2006 .

Experiments in pursuit of pentagonal dodecahedrane: model synthesis of convex polyquinanes

G. Mehta, M. Nair, 1985 .

An alternate route to the C(7)C(13)subunit of erythronolide B via A hydropyran template

M. Nair, S. D. Burke, O. Campopiano, 1987 .

Phytochemical Analysis and Radical Scavenging Activity of the Extracts of Costus picatus Linn and Coccinia indica W & A , two Ethnic Medicinal Plants used in the Treatment of Diabetes mellitus

Sreedevi, M. Nair, G. Jayakumar, 2014 .

Phytochemical Analysis Radical Scavenging Activity of the Extracts of Costus picatus Linn Coccinia indica W& A, two Ethnic Medicinal Plants used in the Treatment of Diabetes mellitus

M. Nair, G. Jayakumar, M. D. Ajithabai, 2011 .

Chemical constituents of Curcuma malabarica

M. Nair, D. Sheeja, 2010 .

Epoxyazadiradione exhibit activities in head and neck squamous cell carcinoma by targeting multiple pathways

Subash C. Gupta, Satya N. Das, S. Aggarwal, 2020, Apoptosis.

Nimbolide, a Limonoid Triterpene, Inhibits Growth of Human Colorectal Cancer Xenografts by Suppressing the Proinflammatory Microenvironment

Y. Mo, B. Aggarwal, S. Prasad, 2013, Clinical Cancer Research.

Nimbolide retards tumor cell migration, invasion, and angiogenesis by downregulating MMP‐2/9 expression via inhibiting ERK1/2 and reducing DNA‐binding activity of NF‐κB in colon cancer cells

S. Babykutty, P. Srinivas, N. R.J., 2012, Molecular carcinogenesis.

Modification of Cysteine 179 of IκBα Kinase by Nimbolide Leads to Down-regulation of NF-κB-regulated Cell Survival and Proliferative Proteins and Sensitization of Tumor Cells to Chemotherapeutic Agents*

B. Aggarwal, R. Kannappan, S. Prasad, 2010, The Journal of Biological Chemistry.

Triterpenoids from Dysoxylum malabaricum.

M. Nair, G. Jayakumar, Y. Fujimoto, 2001, Phytochemistry.

Coronarin D, a labdane diterpene, inhibits both constitutive and inducible nuclear factor-κB pathway activation, leading to potentiation of apoptosis, inhibition of invasion, and suppression of osteoclastogenesis

B. Aggarwal, A. Kunnumakkara, P. Anand, 2008, Molecular Cancer Therapeutics.

Nimbolide from Azadirachta indica and its derivatives plus first-generation cephalosporin antibiotics: a novel drug combination for wound-infecting pathogens

K. Raghu, B. Kumar, S. N. Kumar, 2015 .

Curcuma ecalcarata – new natural source of pinocembrin and piperitenone

K. Rameshkumar, M. Nair, V. George, 2015, Natural product research.

Studies in Lipase Catalyzed Transesterifications: Synthesis of (+)-Albicanol, (+)-Albicanyl Acetate and Chiral Intermediates Useful in the Synthesis of Drimanes and Labdanes

M. Nair, A. Anilkumar, S. Joly, 2000 .

Versatile chiral intermediates for terpenoid synthesis using lipase catalysed acylation

M. Nair, A. Anilkumar, 1996 .

Lipase catalysed regioselective acylation: A facile method for the synthesis of commercially important ambrox intermediate

M. Nair, A. Anilkumar, 1994, Biotechnology Letters.

Versatile Chiral Intermediates for Terpenoid Synthesis Using Lipase Catalyzed Acylation.

M. Nair, A. Anilkumar, 1996 .

FACILE SYNTHESIS OF THE VERSATILE SYNTHON 1-METHYLENE-5,5,8A-TRIMETHYL-2-OXODECAHYDRONAPHTHALENE

M. Nair, A. Anilkumar, 1994 .

Studies on the enzymatic kinetic resolution of β-hydroxy ketones

M. Nair, S. Joly, 2003 .

Ethyl p-methoxycinnamate isolated from a traditional anti-tuberculosis medicinal herb inhibits drug resistant strains of Mycobacterium tuberculosis in vitro.

S. Hoffner, L. Jose, S. Mundayoor, 2011, Fitoterapia.

Isodeoxyelephantopin, a Novel Sesquiterpene Lactone, Potentiates Apoptosis, Inhibits Invasion, and Abolishes Osteoclastogenesis through Suppression of Nuclear Factor-κB (NF-κB) Activation and NF-κB-Regulated Gene Expression

B. Aggarwal, Y. Takada, O. Oommen, 2006, Clinical Cancer Research.

Azadiradione-loaded liposomes with improved bioavailability and anticancer efficacy against triple negative breast cancer

Sasidhar B. Somappa, A. Kunnumakkara, F. Badria, 2021 .

Isodeoxyelephantopin, a Sesquiterpene Lactone Induces ROS Generation, Suppresses NF-κB Activation, Modulates LncRNA Expression and Exhibit Activities Against Breast Cancer

Subash C. Gupta, Anupam Dhasmana, S. Verma, 2019, Scientific Reports.

Molecular mechanisms of anticancer activity of deoxyelephantopin in cancer cells

M. Nair, D. S. Rajalekshmi, F. A. Kabeer, 2017, Integrative medicine research.

Nimbolide Sensitizes Human Colon Cancer Cells to TRAIL through Reactive Oxygen Species- and ERK-dependent Up-regulation of Death Receptors, p53, and Bax*

B. Aggarwal, Subash C. Gupta, Byoungduck Park, 2010, The Journal of Biological Chemistry.

Anti-cancer activities of Bharangin against breast cancer: Evidence for the role of NF-κB and lncRNAs.

Subash C. Gupta, S. Verma, M. Nair, 2018, Biochimica et biophysica acta. General subjects.

Epoxyazadiradione Purified from the Azadirachta indica Seed Induced Mitochondrial Apoptosis and Inhibition of NFκB Nuclear Translocation in Human Cervical Cancer Cells

M. Nair, B. S. Sasidhar, G. Shilpa, 2017, Phytotherapy research : PTR.

Azadirone, a Limonoid Tetranortriterpene, Induces Death Receptors and Sensitizes Human Cancer Cells to Tumor Necrosis Factor-related Apoptosis-inducing Ligand (TRAIL) through a p53 Protein-independent Mechanism

Y. Mo, B. Aggarwal, Subash C. Gupta, 2013, The Journal of Biological Chemistry.

B. Aggarwal, R. Kannappan, S. Prasad, 2010, The Journal of Biological Chemistry.

Cancer Therapy : Preclinical Nimbolide , a Limonoid Triterpene , Inhibits Growth of Human Colorectal Cancer Xenografts by Suppressing the Proin fl ammatory Microenvironment

Y. Mo, B. Aggarwal, S. Prasad, 2013 .

Sesquiterpene Lactones Isolated from Elephantopus scaber L. Inhibits Human Lymphocyte Proliferation and the Growth of Tumour Cell Lines and Induces Apoptosis In Vitro

M. Nair, P. G. Latha, P. Remani, 2012, Journal of biomedicine & biotechnology.

Diels–Alder reactivity of 2-(bromomethyl)-1,4-quinone and 2-bromo-5-(bromomethyl)-1,4-quinone with cyclopentadiene and the synthesis of new substituted pentacyclic systems

M. Nair, S. Joly, U. Sudhir, 2003 .

Formation of novel polycyclic cage compounds through 'uncaging' of readily accessible higher cage compounds

E. Suresh, M. Nair, N. Rath, 2006 .

Synthetic studies in quest of Platonic hydrocarbon dodecahedrane

K. R. Reddy, G. Mehta, M. Nair, 1988, Proceedings / Indian Academy of Sciences.

Experiments in Pursuit of Pentagonal Dodecahedrane: Model Synthesis of Convex Polyquinanes.

G. Mehta, M. Nair, 1986 .

Design of a key synthon for dodecahedrane: (C2v)-C12-tetraquinanedione

G. Mehta, M. Nair, 1985 .

Synthetic design of a spherodial C18-oxa-hexaquinane system: model studies for the synthesis of dodecahedrane

G. Mehta, M. Nair, 1983 .

SYNTHETIC DESIGN OF A SPHEROIDAL C18-OXAHEXAQUINANE SYSTEM: MODEL STUDIES FOR THE SYNTHESIS OF DODECAHEDRANE

G. Mehta, M. Nair, 1983 .

Isodeoxyelephantopin, a novel sesquiterpene lactone, potentiates apoptosis, inhibits invasion, and abolishes osteoclastogenesis through suppression of nuclear factor-kappaB (nf-kappaB) activation and nf-kappaB-regulated gene expression.

B. Aggarwal, Y. Takada, O. Oommen, 2006, Clinical cancer research : an official journal of the American Association for Cancer Research.

Crotepoxide chemosensitizes tumor cells through inhibition of expression of proliferation, invasion, and angiogenic proteins linked to proinflammatory pathway.

B. Aggarwal, S. Prasad, M. Chaturvedi, 2016, The Journal of Biological Chemistry.

Nimbolide sensitizes human colon cancer cells to TRAIL through reactive oxygen species- and ERK-dependent up-regulation of death receptors, p53, and Bax.

B. Aggarwal, Subash C. Gupta, Byoungduck Park, 2016, The Journal of Biological Chemistry.

B. Aggarwal, A. Kunnumakkara, P. Anand, 2008, Molecular Cancer Therapeutics.

Synthesis of novel highly functionalized biologically active polycyclic caged amides

M. Nair, S. Viji, D. Lakshmanan, 2007 .

Nimbolide, a Limonoid Triterpene, Inhibits Growth of Human Colorectal Cancer Xenografts by Suppressing the Proinflammatory Microenvironment

Y. Mo, B. Aggarwal, S. Prasad, 2013, Clinical Cancer Research.

Optimised isolation procedure for biologically active compounds nimbolide and 28-deoxonimbolide from Azadirachta indica leaves

M. Nair, S. Gopal, Deepa Issac, 1997 .