C. Chow

发表

Transition metal complexes as probes of nucleic acids.

J. Barton, C. Chow, 1992, Methods in enzymology.

Helix 69: A Multitasking RNA Motif as a Novel Drug Target

Jun Jiang, C. Chow, Yogo Sakakibara, 2013 .

Aminoglycosides modified by resistance enzymes display diminished binding to the bacterial ribosomal aminoacyl-tRNA site.

L. Kotra, S. Mobashery, C. Chow, 2002, Chemistry & biology.

NMR conformational analysis of p-tolyl furanopyrimidine 2'-deoxyribonucleoside and crystal structure of its 3',5'-di-O-acetyl derivative.

S. Szafert, C. Chow, R. Dembinski, 2005, Bioorganic & medicinal chemistry.

Design, Multigram Synthesis, and in Vitro and in Vivo Evaluation of Propylamycin: A Semisynthetic 4,5-Deoxystreptamine Class Aminoglycoside for the Treatment of Drug-Resistant Enterobacteriaceae and Other Gram-Negative Pathogens.

J. Schacht, A. Vasella, Takayuki Kato, 2019, Journal of the American Chemical Society.

Amino acid-linked platinum(II) analogues have altered specificity for RNA compared to cisplatin.

X. Bao, C. Chow, K. Rijal, 2014, Chemical communications.

Modulation of conformational changes in helix 69 mutants by pseudouridine modifications.

Daya Nidhi Kharel, Jun Jiang, C. Chow, 2015, Biophysical chemistry.

Synthesis and solution conformation studies of 3-substituted uridine and pseudouridine derivatives.

Yu-Cheng Chang, C. Chow, Jayatilake Herath, 2008, Bioorganic & medicinal chemistry.

A single HMG domain in high-mobility group 1 protein binds to DNAs as small as 20 base pairs containing the major cisplatin adduct.

S. Lippard, C. Chow, C. Barnés, 1995, Biochemistry.

Structural and Kinetic Studies of a Cisplatin-modified DNA Icosamer Binding to HMG1 Domain B*

M. Jacobson, S. Lippard, E. Jamieson, 1999, The Journal of Biological Chemistry.

Structure modulation of helix 69 from Escherichia coli 23S ribosomal RNA by pseudouridylations

J. SantaLucia, R. Aduri, Jun Jiang, 2013, Nucleic acids research.

Synthesis and solution conformation studies of the modified nucleoside N(4),2'-O-dimethylcytidine (m(4)Cm) and its analogues.

S. K. Mahto, C. Chow, 2008, Bioorganic & medicinal chemistry.

Amino acid-linked platinum(II) compounds: non-canonical nucleoside preferences and influence on glycosidic bond stabilities

M. Rodgers, X. Bao, Zhihua Yang, 2019, JBIC Journal of Biological Inorganic Chemistry.

Shape-selective cleavage of tRNAPhe by transition metal complexes

J. Barton, C. Chow, 1990 .

HMG domain proteins induce sharp bends in cisplatin-modified DNA.

S. Lippard, C. Chow, J. Whitehead, 1994, Biochemistry.

Solution conformations of two naturally occurring RNA nucleosides: 3-methyluridine and 3-methylpseudouridine.

C. Chow, Jean‐Paul Desaulniers, H. Chui, 2005, Bioorganic & medicinal chemistry.

The synthesis of allyl- and allyloxycarbonyl-protected RNA phosphoramidites. Useful reagents for solid-phase synthesis of RNAs with base-labile modifications

C. Chow, F. Bogdan, 1998 .

New Ionization Processes for Ionizing Nonvolatile Compounds in Mass Spectrometry: The Road of Discovery to Current State-of-the-Art

Scott M. Grayson, V. Shulaev, T. Sanderson, 2020 .

A practical synthesis of the modified RNA nucleoside pseudouridine

P. Grohar, C. Chow, 1999 .

Recognition of G-U mismatches by tris(4,7-diphenyl-1,10-phenanthroline)rhodium(III).

J. Barton, C. Chow, 1992, Biochemistry.

A Structural Basis for RNA−Ligand Interactions

Christine S. Chow, Felicia M. Bogdan, C. Chow, 1997 .

A Structural Basis for RNAminus signLigand Interactions.

C. Chow, F. Bogdan, 1997, Chemical reviews.

Structural determination of arginine-linked cisplatin complexes via IRMPD action spectroscopy: arginine binds to platinum via NO- binding mode.

J. Martens, G. Berden, J. Oomens, 2021, Physical chemistry chemical physics : PCCP.

Monitoring aminoglycoside-induced conformational changes in 16S rRNA through acrylamide quenching.

C. Chow, Pei-Wen Chao, 2007, Bioorganic & medicinal chemistry.

Calculations of pKa Values for a Series of Naturally Occurring Modified Nucleobases.

H. Schlegel, C. Chow, Sebastien P. Hebert, 2022, The journal of physical chemistry. A.

An Advanced Apralog with Increased in vitro and in vivo Activity toward Gram‐negative Pathogens and Reduced ex vivo Cochleotoxicity

J. Schacht, A. Vasella, S. Hobbie, 2020, ChemMedChem.

Combined Approaches to Site-Specific Modification of RNA.

S. K. Mahto, C. Chow, Tek N. Lamichhane, 2008, ACS chemical biology.

Recognition of tertiary structure in tRNAs by Rh(phen)2phi3+, a new reagent for RNA structure-function mapping.

O. Uhlenbeck, J. Barton, L. Behlen, 1992, Biochemistry.

RNA-aminoglycoside antibiotic interactions: fluorescence detection of binding and conformational change.

B Llano-Sotelo, C S Chow, C. Chow, 1999, Bioorganic & medicinal chemistry letters.

Design of novel antibiotics that bind to the ribosomal acyltransfer site.

Lakshmi P Kotra, L. Kotra, S. Mobashery, 2002, Journal of the American Chemical Society.

Probing RNA hairpins with cobalt(III)hexammine and electrospray ionization mass spectrometry

C. Chow, Jason W. Kieltyka, 2006, Journal of the American Society for Mass Spectrometry.

Synthesis of 15N-enriched pseudouridine derivatives.

C. Chow, Jean‐Paul Desaulniers, Bashar Ksebati, 2003, Organic letters.

Probing the stabilizing effects of modified nucleotides in the bacterial decoding region of 16S ribosomal RNA.

S. K. Mahto, C. Chow, 2013, Bioorganic & medicinal chemistry.

Synthesis of helix 69 of Escherichia coli 23S rRNA containing its natural modified nucleosides, m3ψ and ψ

S. Scaringe, C. Chow, Jean‐Paul Desaulniers, 2002 .

Synthesis of a 3-methyluridine phosphoramidite to investigate the role of methylation in a ribosomal RNA hairpin.

S. Scaringe, C. Chow, H. Chui, 2002, Bioorganic & medicinal chemistry.

Effects of nucleotide substitution and modification on the stability and structure of helix 69 from 28S rRNA.

Lawrence J. Clos, Yu-Cheng Chang, C. Chow, 2005, RNA.

Ligand- and pH-induced conformational changes of RNA domain helix 69 revealed by 2-aminopurine fluorescence.

C. Chow, Anne-Cécile E Duc, Sanjaya C Abeysirigunawardena, 2012, Angewandte Chemie.

Evaluation of Hybrid Theoretical Approaches for Structural Determination of a Glycine-Linked Cisplatin Derivative via Infrared Multiple Photon Dissociation (IRMPD) Action Spectroscopy.

G. Berden, J. Oomens, M. Rodgers, 2015, The journal of physical chemistry. A.

Modified Nucleosides in Biochemistry, Biotechnology and Medicine

C. Chow, 2009 .

Selection of heptapeptides that bind helix 69 of bacterial 23S ribosomal RNA.

M. Spaller, C. Chow, C. Rupasinghe, 2013, Bioorganic & medicinal chemistry.

Comparison of solution conformations and stabilities of modified helix 69 rRNA analogs from bacteria and human.

J. SantaLucia, Jun Jiang, C. Chow, 2012, Biopolymers.

A modified fluorescent intercalator displacement assay for RNA ligand discovery.

C. Chow, P. Asare‐Okai, 2011, Analytical biochemistry.

pH-dependent structural changes of helix 69 from Escherichia coli 23S ribosomal RNA.

Sanjaya C. Abeysirigunawardena, C. Chow, Sanjaya C Abeysirigunawardena, 2008, RNA.

FOCUS :N UCLEIC ACIDS IN MASS SPECTROMETRY Probing RNA Hairpins with Cobalt(III)hexammine and Electrospray Ionization Mass Spectrometry

C. Chow, Jason W. Kieltyka, 2006 .

Synthesis of Helix 69 of Escherichia coli 23S rRNA Containing Its Natural Modified Nucleosides, m3Ψ and Ψ.

S. Scaringe, C. Chow, Jean‐Paul Desaulniers, 2003 .

High-mobility-group 1 protein mediates DNA bending as determined by ring closures.

S. Lippard, S. Lippard, C. Chow, 1993, Proceedings of the National Academy of Sciences of the United States of America.

Selection of Peptides Targeting Helix 31 of Bacterial 16S Ribosomal RNA by Screening M13 Phage-Display Libraries

P. Cunningham, C. Chow, Anne-Cécile E Duc, 2011, Molecules.

Identification and role of functionally important motifs in the 970 loop of Escherichia coli 16S ribosomal RNA.

John SantaLucia, Ashesh A Saraiya, J. SantaLucia, 2008, Journal of molecular biology.

Pseudouridines in rRNA helix 69 play a role in loop stacking interactions.

J. SantaLucia, Yu-Cheng Chang, R. Aduri, 2008, Organic & biomolecular chemistry.

Expanding the nucleotide repertoire of the ribosome with post-transcriptional modifications.

S. K. Mahto, Tek N Lamichhane, Christine S Chow, 2007, ACS chemical biology.

Chemical probing for examining the structure of modified RNAs and ligand binding to RNA.

C. Chow, Yogo Sakakibara, Prabuddha Waduge, 2019, Methods.

Post-transcriptional Modifications Modulate rRNA Structure and Ligand Interactions.

Jun Jiang, C. Chow, Hyosuk Seo, 2016, Accounts of chemical research.

Single-molecule FRET reveals a cooperative effect of two methyl group modifications in the folding of human mitochondrial tRNA(Lys).

G. Nienhaus, M. Helm, A. Van Aerschot, 2011, Chemistry & biology.

More pronounced salt dependence and higher reactivity for platination of the hairpin r(CGCGUUGUUCGCG) compared with d(CGCGTTGTTCGCG)

S. Elmroth, C. Chow, Margareta Hägerlöf, 2006, JBIC Journal of Biological Inorganic Chemistry.

Histone stoichiometry and DNA circularization in archaeal nucleosomes.

J. Reeve, K. Bailey, C. Chow, 1999, Nucleic acids research.

Determination of Structural Interaction Between T Box Antiterminator-tRNA Complex : Chemo-enzymatic probing

Sanjaya C. Abeysirigunawardena, C. Chow, Sanjaya C Abeysirigunawardena, 2004 .

Use of a fluorescence assay to determine relative affinities of semisynthetic aminoglycosides to small RNAs representing bacterial and mitochondrial A sites.

C. Chow, D. Crich, Girish C Sati, 2019, Bioorganic & medicinal chemistry.

Redox-Inactive Peptide Disrupting Trx1-Ask1 Interaction for Selective Activation of Stress Signaling.

C. Chow, Y. Ahn, Dilini N Kekulandara, 2018, Biochemistry.

Thermodynamics of RNA hairpins containing single internal mismatches.

C S Chow, C. Chow, M Meroueh, 1999, Nucleic acids research.

Automated reticulocyte counting--an evaluation of GEN-S, Cell-Dyn 3500 and Cell-Dyn 4000.

K. Wong, C. Chow, P. Yu, 1999, Clinical and Laboratory Haematology.

Reactions of platinum(II) complexes with a DNA hairpin, d(CGCGTTGTTCGCG): structural characterization and kinetic studies

S. Elmroth, C. Chow, Johan Kjellström, 2000 .

A Structural Basis for RNA-Ligand Interactions

Christine S. Chow, Felicia M. Bogdan, C. Chow, 1997 .

Production of Nanostructures of DNA on Surfaces

Nabil A. Amro, Gang-yu Liu, Maozi Liu, 2002 .

The use of electrospray ionization mass spectrometry to monitor RNA-ligand interactions.

C. Chow, D. Dremann, 2019, Methods in enzymology.

Delineation of structural domains in eukaryotic 5S rRNA with a rhodium probe.

J. Barton, C. Chow, P. Huber, 1992, Biochemistry.

Calculated pKa Values for a Series of Aza- and Deaza-Modified Nucleobases

H. Schlegel, C. Chow, Alan J Mlotkowski, 2023, The journal of physical chemistry. A.

Expression and in vivo characterization of the antimicrobial peptide oncocin and variants binding to ribosomes.

P. Cunningham, S. Trimpin, W. Colangelo, 2020, Biochemistry.

Role of pseudouridine in structural rearrangements of helix 69 during bacterial ribosome assembly.

C. Chow, Yogo Sakakibara, 2012, ACS chemical biology.

Pseudouridine modifications influence binding of aminoglycosides to helix 69 of bacterial ribosomes.

C. Chow, Yogo Sakakibara, 2017, Organic & biomolecular chemistry.

Cisplatin Targeting of Bacterial Ribosomal RNA Hairpins

C. Chow, Gayani N. P. Dedduwa-Mudalige, 2015, International journal of molecular sciences.

Probing conformational states of modified helix 69 in 50S ribosomes.

C. Chow, Yogo Sakakibara, 2011, Journal of the American Chemical Society.

Structural and Kinetic Studies of a Cisplatin-modified DNA Icosamer Binding to HMG 1 Domain B

M. Jacobson, S. Lippard, E. Jamieson, 1999 .

Synthesis and characterization of modified nucleotides in the 970 hairpin loop of Escherichia coli 16S ribosomal RNA.

C. Chow, N. Abeydeera, Christine S. Chow, 2009, Bioorganic & medicinal chemistry.

Characterization of a novel alpha1,2-fucosyltransferase of Escherichia coli O128:b12 and functional investigation of its common motif.

W. Yi, P. Wang, Jie Shen, 2008, Biochemistry.

FOCUS: NUCLEIC ACIDS IN MASS SPECTROMETRY Probing RNA Hairpins with Cobalt(III)hexammine and Electrospray Ionization Mass Spectrometry

C. Chow, Jason W. Kieltyka, 2006 .

A modified fluorescent intercalator displacement assay for RNA ligand discovery.

C. Chow, P. Asare‐Okai, 2011, Analytical biochemistry.

The development of peptide ligands that target helix 69 rRNA of bacterial ribosomes.

C. Chow, D. Dremann, 2016, Bioorganic & medicinal chemistry.

Identification of a new alpha1,2-fucosyltransferase involved in O-antigen biosynthesis of Escherichia coli O86:B7 and formation of H-type 3 blood group antigen.

W. Yi, Jie Shen, Xianwei Liu, 2008, Biochemistry.