K. Fox

发表

DNAase I footprinting of restriction enzymes.

K. Fox, 1988, Biochemical and biophysical research communications.

Affinity of mismatch-binding protein MutS for heteroduplexes containing different mismatches.

T. Brown, T Brown, K R Fox, 2001, The Biochemical journal.

Footprinting: a method for determining the sequence selectivity, affinity and kinetics of DNA-binding ligands.

Andrew J. Hampshire, David A Rusling, Keith R Fox, 2007, Methods.

Structural basis of DNA duplex distortion induced by thiazole-containing hairpin polyamides

J. Parkinson, G. Burley, K. Fox, 2017, Nucleic acids research.

Sequence-selective binding of C8-conjugated pyrrolobenzodiazepines (PBDs) to DNA.

P. Jackson, K. Fox, M. Basher, 2017, Biophysical chemistry.

Sequence-specific recognition of DNA nanostructures.

David A Rusling, K. Fox, 2014, Methods.

Thioester Bonds of Thiocoraline Can Be Replaced with NMe-Amide Bridges without Affecting Its DNA-Binding Properties.

Judit Tulla-Puche, F. Albericio, K. Fox, 2014, ACS medicinal chemistry letters.

GC-targeted C8-linked pyrrolobenzodiazepine-biaryl conjugates with femtomolar in vitro cytotoxicity and in vivo antitumor activity in mouse models.

P. Jackson, R. B. Pedley, J. Hartley, 2013, Journal of medicinal chemistry.

Secondary binding sites for heavily modified triplex forming oligonucleotides

T. Brown, K. Fox, Antonia S. Cardew, 2011, Nucleic acids research.

Antistaphylococcal activity of DNA-interactive pyrrolobenzodiazepine (PBD) dimers and PBD-biaryl conjugates

Denise E. Waldron, M. de la Fuente, P. Taylor, 2012, The Journal of antimicrobial chemotherapy.

DNA triplex formation with 5-dimethylaminopropargyl deoxyuridine

David A Rusling, T. Brown, K. Fox, 2009, Nucleic acids research.

The effects of local DNA sequence on the interaction of ligands with their preferred binding sites.

Andrew J. Hampshire, Keith R Fox, K. Fox, 2008, Biochimie.

DNA structural variations produced by actinomycin and distamycin as revealed by DNAase I footprinting.

M. Waring, K. Fox, 1984, Nucleic acids research.

Footprinting reveals that nogalamycin and actinomycin shuffle between DNA binding sites.

M. Waring, K. Fox, 1986, Nucleic acids research.

High resolution hydroxyl radical footprinting of the binding of mithramycin and related antibiotics to DNA.

K. Fox, B. M. Cons, 1989, Nucleic acids research.

Visualising the kinetics of dissociation of actinomycin from individual sites in mixed sequence DNA by DNase I footprinting.

K. Fox, M. Fletcher, 1993, Nucleic acids research.

Kinetic studies on the formation of acridine‐linked DNA triple helices

K. Fox, 1995, FEBS letters.

Dissociation of the AT-specific bifunctional intercalator [N-MeCys3,N-MeCys7]TANDEM from TpA sites in DNA.

R. K. Olsen, K. Fox, M. Fletcher, 1995, The Biochemical journal.

Dissociation kinetics of actinomycin D from individual GpC sites in DNA.

K. Fox, M. Fletcher, 1996, European journal of biochemistry.

Visualising the dissociation of sequence selective ligands from individual binding sites on DNA

K. Fox, M. Fletcher, Michael C. Fletcher, 1996, FEBS letters.

Dissociation kinetics of echinomycin from CpG binding sites in different sequence environments.

K. Fox, M. Fletcher, 1996, Biochemistry.

Kinetic studies on the formation of intermolecular triple helices.

K. Fox, H. Paes, 1997, Nucleic acids research.

Interaction of minor groove binding ligands with long AT tracts.

A. Abu-daya, K. Fox, 1997, Nucleic acids research.

DNA sequence recognition by an isopropyl substituted thiazole polyamide.

Tom Brown, T. Brown, Keith R Fox, 2004, Nucleic acids research.

Four base recognition by triplex-forming oligonucleotides at physiological pH

Yang Wang, Tom Brown, Keith R. Fox, 2005, Nucleic acids research.

Combining nucleoside analogues to achieve recognition of oligopurine tracts by triplex‐forming oligonucleotides at physiological pH

David A Rusling, T. Brown, Vicki E. C. Powers, 2005, FEBS letters.

DNA sequence recognition by an imidazole-containing isopropyl-substituted thiazole polyamide (thiazotropsin B).

Andrew J. Hampshire, T. Brown, R. Waigh, 2006, Bioorganic & medicinal chemistry letters.

DNA sequence specificity of triplex-binding ligands.

S. Neidle, T. Brown, K. Fox, 2003, European journal of biochemistry.

Stable DNA triple helix formation using oligonucleotides containing 2'-aminoethoxy,5-propargylamino-U.

B. Cuenoud, T. Brown, M. Sollogoub, 2002, Biochemistry.

DNA triple helix stabilisation by a naphthylquinoline dimer

L. Strekowski,, K. Fox, M. Keppler, 1999, FEBS letters.

DNA triple helix stabilisation by covalent attachment of a triplex-specific ligand.

L. Strekowski,, T. Brown, K. Fox, 1999, Biochimica et biophysica acta.

Footprinting studies on ligands which stabilize DNA triplexes: effects on stringency within a parallel triple helix.

L. Strekowski,, W. Wilson, S. Chandler, 1995, Biochemistry.

Effect of a triplex-binding ligand on parallel and antiparallel DNA triple helices using short unmodified and acridine-linked oligonucleotides.

L. Strekowski,, W. Wilson, K. Fox, 1994, Biochemistry.

DNA sequence specificity of a naphthylquinoline triple helix-binding ligand.

L. Strekowski,, K. Fox, S. Cassidy, 1996, Nucleic acids research.

Coralyne has a preference for intercalation between TA.T triples in intramolecular DNA triple helices.

A. Lane, T. Brown, K. Fox, 1997, Nucleic acids research.

Efficient solid-phase-based total synthesis of the bisintercalator TANDEM.

Andrew J. Hampshire, M. Zloh, J. Malkinson, 2005, The Journal of organic chemistry.

Footprinting at low temperatures: evidence that ethidium and other simple intercalators can discriminate between different nucleotide sequences.

M. Waring, K. Fox, 1987, Nucleic acids research.

The effects of actinomycin on the structure of dAn.dTn and (dA-dT)n regions surrounding its GC binding site. A footprinting study.

K. Fox, K. Waterloh, 1991, The Journal of biological chemistry.

Probing the conformations of eight cloned DNA dodecamers; CGCGAATTCGCG, CGCGTTAACGCG, CGCGTATACGCG, CGCGATATCGCG, CGCAAATTTGCG, CGCTTTAAAGCG, CGCGGATCCGCG and CGCGGTACCGCG.

K. Fox, 1992, Nucleic acids research.

Biaryl polyamides as a new class of DNA quadruplex-binding ligands.

S. Neidle, M. Gunaratnam, A. Reszka, 2009, Chemical communications.

DNA sequence preferences of several AT-selective minor groove binding ligands.

A. Abu-daya, K. Fox, P. Brown, 1995, Nucleic acids research.

Exceptionally slow kinetics of the intramolecular quadruplex formed by the Oxytricha telomeric repeat.

P. A. Rachwal, T. Brown, K. Fox, 2005, Organic & biomolecular chemistry.

Inosine substitutions demonstrate that intramolecular DNA quadruplexes adopt different conformations in the presence of sodium and potassium.

K. Fox, A. Risitano, 2005, Bioorganic & medicinal chemistry letters.

Incorporation of fluorotryptophan into triostin antibiotics by Streptomyces triostinicus.

M. Waring, D. Williams, K. Fox, 1985, Journal of general microbiology.

Effects of sequence selective drugs on the gel mobility of a bent DNA fragment.

K. Fox, B. M. Cons, 1990, Biochemical and biophysical research communications.

DNA sequence recognition by under-methylated analogues of triostin A.

M. Waring, R. K. Olsen, K. Fox, 1986, Nucleic acids research.

Kinetic evidence that echinomycin migrates between potential DNA binding sites.

M. Waring, K. Fox, 1985, Nucleic acids research.

Molecular Aspects of the Interaction between Quinoxaline Antibiotics and Nucleic Acids

M. Waring, K. Fox, 1983 .

Preparation and DNA-binding properties of substituted triostin antibiotics

M. Waring, K. Fox, A. Cornish, 1983, Antimicrobial Agents and Chemotherapy.

Differential inhibition of a restriction enzyme by quinoxaline antibiotics.

M. Waring, A. Malcolm, K. Fox, 1982, Biochimica et biophysica acta.

Kinetics of dissociation of quinoxaline antibiotics from DNA.

M. Waring, K. Fox, 1981, Biochimica et biophysica acta.

Changes in contour length of polydeoxynucleotide fragments

M. Waring, N. Harrison, K. Fox, 1981, FEBS letters.

Synthesis of bisquinoline–pyrrole oligoamide as G-quadruplex binding ligand

C. Ong, K. Fox, Meng-Chi Liu, 2012 .

The effects of DNA supercoiling on G-quadruplex formation

K. Fox, D. A. Sekibo, 2017, Nucleic acids research.

Formation of stable DNA triplexes.

T. Brown, K. Fox, 2011, Biochemical Society transactions.

2'-Aminoethoxy-2-amino-3-methylpyridine in triplex-forming oligonucleotides: high affinity, selectivity and resistance to enzymatic degradation.

T. Brown, K. Fox, Montserrat Shelbourne, 2011, Chemistry.

CG base pair recognition within DNA triple helices by modified N-methylpyrrolo-dC nucleosides.

T. Brown, K. Fox, M. Edrees, 2010, Organic & biomolecular chemistry.

The stability of triplex DNA is affected by the stability of the underlying duplex.

P. A. Rachwal, David A Rusling, T. Brown, 2009, Biophysical Chemistry.

Potent Triple Helix Stabilization by 5′,3′‐Modified Triplex‐Forming Oligonucleotides

T. Brown, K. Fox, Z. Zhao, 2009, Chembiochem : a European journal of chemical biology.

Kinetic studies on the formation of DNA triplexes containing the nucleoside analogue 2'-O-(2-aminoethyl)-5-(3-amino-1-propynyl)uridine.

David A Rusling, T. Brown, K. Fox, 2008, Organic & biomolecular chemistry.

DNA triple-helix formation at target sites containing duplex mismatches.

David A Rusling, T. Brown, K. Fox, 2006, Biophysical chemistry.

Stable recognition of TA interruptions by triplex forming oligonucleotides containing a novel nucleoside.

David A Rusling, T. Brown, Vicki E. C. Powers, 2005, Biochemistry.

5-(1-propargylamino)-2'-deoxyuridine (UP): a novel thymidine analogue for generating DNA triplexes with increased stability.

T. Brown, S. Bergqvist, K. Fox, 1999, Nucleic acids research.

Recognition of GC base pairs by triplex forming oligonucleotides containing nucleosides derived from 2-aminopyridine.

S. Neidle, J. Trent, C. Reese, 1997, Nucleic acids research.

Recognition of CG inversions in DNA triple helices by methylated 3H-pyrrolo[2,3-d]pyrimidin-2(7H)-one nucleoside analogues.

David A Rusling, Rohan T Ranasinghe, T. Brown, 2005, Chemical communications.

Thermodynamic and kinetic stability of intermolecular triple helices containing different proportions of C+*GC and T*AT triplets.

T. Brown, K. Fox, P. L. James, 2003, Nucleic acids research.

Combination of His-tagged T4 endonuclease VII with microplate array diagonal gel electrophoresis for high-throughput mutation scanning.

I. Day, K. Alharbi, Xiao-he Chen, 2005, Clinical chemistry.

Secondary binding sites for triplex-forming oligonucleotides containing bulges, loops, and mismatches in the third strand.

D. Gowers, E. Flashman, K. Fox, 2000, Biochemistry.

Nucleosome core particles inhibit DNA triple helix formation.

K. Fox, P. Brown, 1996, The Biochemical journal.

Effects of a hairpin polyamide on DNA melting: comparison with distamycin and Hoechst 33258.

B. Nordén, T. Brown, Loic le Strat, 2004, Biophysical Chemistry.

Interaction of mithramycin with metal ions and DNA.

K. Fox, B. M. Cons, 1989, Biochemical and biophysical research communications.

Long (dA)n.(dT)n tracts can form intramolecular triplexes under superhelical stress.

K. Fox, 1990, Nucleic acids research.

A polarized-light spectroscopy study of interactions of a hairpin polyamide with DNA.

B. Nordén, P. Lincoln, C. E. Caesar, 2006, Biophysical journal.

Footprinting studies with nucleosome-bound DNA.

K. Fox, P. Brown, 1997, Methods in molecular biology.

Melting temperature measurement and mesoscopic evaluation of single, double and triple DNA mismatches†

G. Weber, T. Brown, K. Fox, 2020, Chemical science.

Response of Staphylococcus aureus to subinhibitory concentrations of a sequence-selective, DNA minor groove cross-linking pyrrolobenzodiazepine dimer.

J. Hinds, P. Taylor, M. Doyle, 2009, The Journal of antimicrobial chemotherapy.

Molecular insights into miRNA processing by Arabidopsis thaliana SERRATE

B. Stoddard, K. Fox, S. Machida, 2021, Nucleic acids research.

Stopped-flow kinetic studies on the interaction between echinomycin and DNA.

M. Waring, K. Fox, 1984, Biochemistry.

Equilibrium and kinetic studies on the binding of des-N-tetramethyltriostin A to DNA.

M. Waring, R. K. Olsen, K. Fox, 1982, Biochimica et biophysica acta.

Stabilisation of TG- and AG-containing antiparallel DNA triplexes by triplex-binding ligands.

S. Neidle, K. Fox, M. Keppler, 2001, Nucleic acids research.

DNA triple-helix formation on nucleosome-bound poly(dA).poly(dT) tracts.

K. Fox, P. Brown, 1998, The Biochemical journal.

Relative stability of triplexes containing different numbers of T.AT and C+.GC triplets.

K. Fox, M. Keppler, 1997, Nucleic acids research.

First synthesis of 1-deazacytidine, the C-nucleoside analogue of cytidine

T. Brown, Vicki E. C. Powers, M. Sollogoub, 2002 .

Sequence selective binding of bis-daunorubicin WP631 to DNA.

W. Priebe, K. Fox, I. Fokt, 2004, European Journal of Biochemistry.

Drug-DNA Interaction Protocols

K. Fox, 1997, Methods in Molecular Biology.

Symmetric bis-benzimidazoles: new sequence-selective DNA-binding molecules

S. Neidle, L. Kèlland, J. Hartley, 1999 .

Kinetics of dissociation of nogalamycin from DNA: comparison with other anthracycline antibiotics.

M. Waring, K. Fox, C. Brassett, 1985, Biochimica et biophysica acta.

Kinetics of the interaction between echinomycin and deoxyribonucleic acid.

M. Waring, L. P. Wakelin, K. Fox, 1981, Biochemistry.

INTERACTION BETWEEN SYNTHETIC ANALOGUES OF QUINOXALINE ANTIBIOTICS AND NUCLEIC ACIDS: ROLE OF THE DISULPHIDE CROSS‐BRIDGE AND d‐AMINO ACID CENTRES IN DES‐N‐TETRAMETHYL‐TRIOSTIN A

M. Waring, P. Chakravarty, R. K. Olsen, 1980, British journal of pharmacology.

A facile synthesis of 2-substituted N-tert-butoxycarbonyl-N-methyl-1,3-propanediamines, key intermediates for the preparation of triplex DNA-specific intercalators

L. Strekowski,, K. Fox, Y. Gulevich, 1995 .

Solid-Phase Synthesis of Duocarmycin Analogues and the Effect of C-Terminal Substitution on Biological Activity.

M. O'Connell, H. Sheldrake, K. Fox, 2015, The Journal of organic chemistry.

DNase I footprinting.

K. Fox, Antonia S. Cardew, 2010, Methods in molecular biology.

Interaction of Hoechst 33258 and echinomycin with nucleosomal DNA fragments containing isolated ligand binding sites.

K. Leslie, K. Fox, 2002, Biochemistry.

A Cyclic Peptide Inhibitor of HIF-1 Heterodimerization That Inhibits Hypoxia Signaling in Cancer Cells

Suzanne A. Eccles, Keith R. Fox, Ali Tavassoli, 2013, Journal of the American Chemical Society.

Targeting DNA with triplexes.

K R Fox, K. Fox, Keith R. Fox, 2000, Current medicinal chemistry.

Site and sequence specificity of the daunomycin-DNA interaction.

M. Waring, J. Chaires, J. Herrera, 1987, Biochemistry.

Preferred binding sites for [N-MeCYs(3), N-MeCys(7)]TANDEM determined using a universal footprinting substrate.

K. Fox, M. Lavesa, 2001, Analytical biochemistry.

High-resolution footprinting studies of drug-DNA complexes using chemical and enzymatic probes.

M. Waring, K. Fox, 2001, Methods in enzymology.

Secondary binding sites for triplex-forming oligonucleotides containing bulges, loops, and mismatches in the third strand

D. Gowers, E. Flashman, K. Fox, 2000 .

DNase I footprinting of triple helix formation at polypurine tracts by acridine-linked oligopyrimidines: stringency, structural changes and interaction with minor groove binding ligands.

T. Stonehouse, K. Fox, 1994, Biochimica et biophysica acta.

Diethyl pyrocarbonate can detect a modified DNA structure induced by the binding of quinoxaline antibiotics.

M. Waring, M. J. Mclean, J. Portugal, 1988, Nucleic acids research.

Diethylpyrocarbonate and permanganate provide evidence for an unusual DNA conformation induced by binding of the antitumour antibiotics bleomycin and phleomycin.

G. Grigg, K. Fox, 1988, Nucleic acids research.

Nucleotide sequence binding preferences of nogalamycin investigated by DNase I footprinting.

M. Waring, K. Fox, 1986, Biochemistry.

Synthesis and Biological Evaluation of a Novel C8-Pyrrolobenzodiazepine (PBD) Adenosine Conjugate. A Study on the Role of the PBD Ring in the Biological Activity of PBD-Conjugates

G. Wells, S. Bhakta, K. Fox, 2020, Molecules.

Synthesis of directly linked diazine isosteres of pyrrole-polyamide that photochemically cleave DNA.

C. Ong, K. Fox, Meng-Chi Liu, 2012, Organic & biomolecular chemistry.

DNA binding of a short lexitropsin.

Blair F. Johnston, S. Mackay, J. Parkinson, 2004, Bioorganic & medicinal chemistry letters.

Minor groove binding ligands alter the rotational positioning of DNA fragments on nucleosome core particles.

K. Fox, P. Brown, 1996, Journal of molecular biology.

Towards mixed sequence recognition by triple helix formation.

D. Gowers, K R Fox, K. Fox, 1999, Nucleic acids research.

A molecular anchor for stabilizing triple-helical DNA.

S. Neidle, T. C. Jenkins, K. Fox, 1995, Proceedings of the National Academy of Sciences of the United States of America.

DNA sequence-selective C8-linked pyrrolobenzodiazepine–heterocyclic polyamide conjugates show anti-tubercular-specific activities

S. Bhakta, Timothy D McHugh, D. Evangelopoulos, 2016, The Journal of Antibiotics.

Synthesis, anti-mycobacterial activity and DNA sequence-selectivity of a library of biaryl-motifs containing polyamides.

S. Bhakta, J. Guzman, Arundhati Maitra, 2015, Bioorganic & medicinal chemistry.

Amide bond direction modulates G-quadruplex recognition and telomerase inhibition by 2,6 and 2,7 bis-substituted anthracenedione derivatives.

S. Moro, G. Parkinson, S. Neidle, 2008, Bioorganic & medicinal chemistry.

Stabilization of DNA triple helices by a series of mono- and disubstituted amidoanthraquinones.

S. Neidle, J. Trent, A. Reszka, 1999, European journal of biochemistry.

Preferred binding sites for the bifunctional intercalator TANDEM determined using DNA fragments that contain every symmetrical hexanucleotide sequence.

Andrew J. Hampshire, K. Fox, 2008, Analytical biochemistry.

Evidence of different binding sites for nogalamycin in DNA revealed by association kinetics.

M. Waring, K. Fox, 1984, Biochimica et biophysica acta.

Cleavage of fragments containing DNA mismatches by enzymic and chemical probes.

T. Brown, K. Fox, James Brown, 2003, The Biochemical journal.

Synthesis of a novel bis-amino-modified thymidine monomer for use in DNA triplex stabilisation

T. Brown, M. Sollogoub, K. Fox, 2000 .

DNA triple helix formation at target sites containing several pyrimidine interruptions: stabilization by protonated cytosine or 5-(1-propargylamino)dU.

T. Brown, D. Gowers, K. Fox, 1999, Biochemistry.

Alternate-strand DNA triple-helix formation using short acridine-linked oligonucleotides.

K. Fox, E. Washbrook, 1994, The Biochemical journal.

An extra dimension in nucleic acid sequence recognition

T. Brown, K. Fox, 2005, Quarterly Reviews of Biophysics.

High throughput measurement of duplex, triplex and quadruplex melting curves using molecular beacons and a LightCycler.

Tom Brown, T. Brown, M. Sollogoub, 2002, Nucleic acids research.

Triple helix formation at (AT)n adjacent to an oligopurine tract.

D. Gowers, K. Fox, 1998, Nucleic acids research.

2′-O-Dimethylaminoethoxyuridine and 5-Dimethylaminopropargyl Deoxyuridine for at Base Pair Recognition in Triple Helices

T. Brown, K. Fox, Guomei Peng, 2007, Nucleosides, Nucleotides & Nucleic Acids.

Selectivity and affinity of triplex-forming oligonucleotides containing 2'-aminoethoxy-5-(3-aminoprop-1-ynyl)uridine for recognizing AT base pairs in duplex DNA.

David A Rusling, T. Brown, Vicki E. C. Powers, 2004, Nucleic acids research.

Synthesis of a Novel Bis-amino-modified Thymidine Monomer for Use in DNA Triplex Stabilization.

T. Brown, M. Sollogoub, K. Fox, 2001 .

Synthesis of Anthraquinone Oligonucleotides for Triplex Stabilization

T. Brown, K. Fox, Guomei Peng, 2007, Nucleosides, Nucleotides & Nucleic Acids.

DNA triple helix formation at oligopurine sites containing multiple contiguous pyrimidines.

D. Gowers, K. Fox, 1997, Nucleic acids research.

Comparison of antiparallel A.AT and T.AT triplets within an alternate strand DNA triple helix.

K. Fox, E. Washbrook, 1994, Nucleic acids research.

Extension of DNA triple helix formation to a neighbouring (AT) n site

K. Fox, Simon P. Chandler, 1995, FEBS Letters.

A novel series of DNA triple helix-binding ligands.

A. Tsotinis, T. C. Jenkins, K. Fox, 1996, Biochemical and biophysical research communications.

2′-Substituted 2-amino-3-methylpyridine ribonucleosides in triplex-forming oligonucleotides: triplex stability is determined by chemical environment

T. Brown, N. Gale, M. Light, 2011 .

Specificity of antiparallel DNA triple helix formation.

S. Chandler, K. Fox, 1996, Biochemistry.

Triple-helix formation at different positions on nucleosomal DNA.

K. Fox, P. Brown, C. Madden, 1998, Biochemistry.

Bleomycin-DNA Interactions

K. Fox, K. Nightingale, 1994 .

Triplex-directed covalent cross-linking of a DNA nanostructure.

David A Rusling, T. Brown, I. Nandhakumar, 2012, Chemical communications.

DNA sequence preferences for an intercalating porphyrin compound revealed by footprinting.

M. Waring, S. Neidle, K. Ford, 1987, Nucleic acids research.

Triple helix formation at A8XA8·T8YT8

K. Fox, Simon P. Chandler, 1993, FEBS letters.

Interaction of mithramycin with DNA fragments complexed with nucleosome core particles: comparison with distamycin and echinomycin.

K. Fox, B. M. Cons, 1993, Biochemistry.

Wrapping of genomic polydA.polydT tracts around nucleosome core particles.

K. Fox, 1992, Nucleic acids research.

DNA Structural Changes Induced by Intermolecular Triple Helix Formation

David A Rusling, T. Brown, K. Fox, 2020, ACS omega.

Kinetic evidence for redistribution of actinomycin molecules between potential DNA-binding sites.

M. Waring, K. Fox, Keith R. Fox, 1984, European journal of biochemistry.

Influence of loop size on the stability of intramolecular DNA quadruplexes.

Keith R Fox, K. Fox, Antonina Risitano, 2004, Nucleic acids research.

Interaction of berenil with the tyrT DNA sequence studied by footprinting and molecular modelling. Implications for the design of sequence-specific DNA recognition agents.

S Neidle, S. Neidle, C. Laughton, 1990, Nucleic acids research.

A Mutant of Uracil DNA Glycosylase That Distinguishes between Cytosine and 5-Methylcytosine

T. Brown, K. Fox, S. Kimber, 2014, PloS one.

Editorial: CRISPR in Nucleic Acids Research

B. Stoddard, K. Fox, 2016, Nucleic acids research.

Quadruplex melting.

P. A. Rachwal, K. Fox, 2007, Methods.

Intramolecular DNA quadruplexes with different arrangements of short and long loops

P. A. Rachwal, T. Brown, K. Fox, 2007, Nucleic acids research.

Sequence effects of single base loops in intramolecular quadruplex DNA

Tom Brown, P. A. Rachwal, T. Brown, 2007, FEBS letters.

Effect of G-tract length on the topology and stability of intramolecular DNA quadruplexes.

P. A. Rachwal, T. Brown, K. Fox, 2007, Biochemistry.

Stability of intramolecular DNA quadruplexes: comparison with DNA duplexes.

Keith R Fox, K. Fox, Antonina Risitano, 2003, Biochemistry.

Triplex-directed recognition of a DNA nanostructure assembled by crossover strand exchange.

David A Rusling, T. Brown, I. Nandhakumar, 2012, ACS nano.

Recognition of GT mismatches by Vsr mismatch endonuclease

Tom Brown, Keith R. Fox, Sarah L. Allinson, 2000, Nucleic Acids Res..

Aminoacyl-anthraquinone conjugates as telomerase inhibitors: synthesis, biophysical and biological evaluation.

S. Neidle, M. Palumbo, G. Zagotto, 2008, Journal of medicinal chemistry.

A simplified and easy‐to‐use HIP HOP assay provides insights into chalcone antifungal mechanisms of action

B. Panaretou, A. Maxwell, T. Prescott, 2022, FEBS letters.

The stability of intramolecular DNA quadruplexes with extended loops forming inter- and intra-loop duplexes.

K. Fox, A. Risitano, 2003, Organic & biomolecular chemistry.

Editorial: NAR Surveys the Past, Present and Future of Restriction Endonucleases

B. Stoddard, W. Dynan, K. Fox, 2013, Nucleic acids research.

The electrophoretic mobility of DNA three‐way junctions is affected by the sequence of overhanging single‐stranded ends

R. Assenberg, K. Fox, René Assenberg, 2001, Electrophoresis.

Kinetic stability of intermolecular DNA quadruplexes.

Keith R Fox, K. Fox, Elena E Merkina, 2005, Biophysical journal.

The effect of sequence context on the activity of cytosine DNA glycosylases.

T. Brown, K. Fox, S. Kimber, 2015, Molecular bioSystems.

Sequence-dependent folding of DNA three-way junctions.

R. Assenberg, K. Fox, A. Weston, 2002, Nucleic acids research.

Binding of quinoline analogues of echinomycin to deoxyribonucleic acid. Role of the chromophores.

M. Waring, D. Goodwin, D. Gauvreau, 1980, The Biochemical journal.

FOOTPRINTING STUDIES OF THE INTERACTION OF QUINOMYCIN ANTIBIOTIC UK63052 WITH DNA: COMPARISON WITH ECHINOMYCIN

M. Waring, K. Fox, 2006 .

Footprinting studies of the interaction of quinomycin antibiotic UK63052 with DNA: comparison with echinomycin.

K. Fox, 1990, The Journal of antibiotics.

DNA sequence recognition by a novel series of minor groove-binding ligands.

Y. Yan, B. Gong, K. Fox, 1999, Anti-cancer drug design.

Light-activated cleavage of DNA by cobalt-bleomycin.

K. Fox, K. Nightingale, 1994, European journal of biochemistry.

Functionalizing Designer DNA Crystals with a Triple-Helical Veneer

Arun Richard Chandrasekaran, Chengde Mao, Tom Brown, 2014, Angewandte Chemie.

DNA sequence preferences for the anti‐cancer drug mitoxanthrone and related anthraquinones revealed by DNase I footprinting

M. Waring, S. Neidle, K. Fox, 1986, FEBS letters.

Structural Requirements for DNA Intercalation and their Relevance to Drug Design

M. Waring, K. Fox, S. Haylock, 1984 .

Sequence selective binding of ditrisarubicin B to DNA: comparison with daunomycin

K. Fox, S. Kunimoto, 1989, FEBS Letters.

DNA-sequence binding preference of the GC-selective ligand mithramycin. Deoxyribonuclease-I/deoxyribonuclease-II and hydroxy-radical footprinting at CCCG, CCGC, CGGC, GCCC and GGGG flanked by (AT)n and An.Tn.

K. Fox, J. Marks, M. Carpenter, 1993, European journal of biochemistry.

Stability of the different arms of a DNA tetrahedron and its interaction with a minor groove ligand.

David A Rusling, T. Brown, K. Fox, 2019, Biophysical chemistry.

Studies of the interaction of a meta-hydroxy analogue of hoechst 33258 with DNA by melting temperature, footprinting and high-resolution 1H NMR spectroscopy

K. Douglas, J. Parkinson, J. Barber, 1992 .

BIROn - Birkbeck Institutional Research Online DNA sequence-selective C8-linked

S. Bhakta, Timothy D McHugh, D. Evangelopoulos, 2021 .

DNA structure influences sequence specific cleavage by bleomycin.

K. Fox, K. Nightingale, 1993, Nucleic acids research.

DNA sequence-selective C 8-linked pyrrolobenzodiazepine ( PBD )-heterocyclic polyamide 1 conjugates show anti-tubercular specific activities 2

S. Bhakta, Timothy D McHugh, D. Evangelopoulos, 2017 .

Footprinting studies on the effect of echinomycin on the structure of a bent DNA fragment.

K. Fox, E. Kentebe, 1990, The Biochemical journal.

The Novel DNA Binding Mechanism of Ridinilazole, a Precision Clostridiodes difficile Antibiotic

K. Garey, T. Avis, S. Reich, 2023, Antimicrobial agents and chemotherapy.

DNA triple-helix formation on nucleosome core particles. Effect of length of the oligopurine tract.

K. Fox, P. Brown, 1999, European journal of biochemistry.

DNA sequence-selective G-A cross-linking ADC payloads for use in solid tumour therapies

P. Jackson, K. Fox, D. Thurston, 2022, Communications Biology.

The effect of HhaI methylation on DNA local structure.

K. Fox, 1986, The Biochemical journal.

Footprinting studies of DNA-sequence recognition by nogalamycin.

K. Fox, Z. Alam, 1992, European journal of biochemistry.

Editorial: Nucleic Acids Research and Nucleic Acid Therapeutics

B. Stoddard, A. Khvorova, W. Dynan, 2018, Nucleic acids research.

Chapter 1:DNA Recognition by Parallel Triplex Formation

David A Rusling, T. Brown, K. Fox, 2018 .

Synthesis and properties of triplex-forming oligonucleotides containing 2'-O-(2-methoxyethyl)-5-(3-aminoprop-1-ynyl)-uridine.

Nuria Vergara-Irigaray, T. Brown, L. Holden-Dye, 2010, Bioorganic & medicinal chemistry.

The use of micrococcal nuclease as a probe for drug-binding sites on DNA.

M. Waring, K. Fox, 1987, Biochimica et biophysica acta.

DNA binding, solubility, and partitioning characteristics of extended lexitropsins.

A. Pitt, M. Scobie, R. Waigh, 2000, Journal of medicinal chemistry.

Investigations into the sequence-selective binding of mithramycin and related ligands to DNA.

K. Fox, N. Howarth, 1985, Nucleic acids research.

Triplex staples: DNA double-strand cross-linking at internal and terminal sites using psoralen-containing triplex-forming oligonucleotides.

T. Brown, Vicki E. C. Powers, K. Fox, 2006, Bioconjugate chemistry.

Sequence-specific recognition of DNA nanostructures.

David A Rusling, K. Fox, 2014, Methods.

Potent Triple Helix Stabilization by 5′,3′‐Modified Triplex‐Forming Oligonucleotides

T. Brown, K. Fox, Nouha Ben Gaied, 2009, Chembiochem : a European journal of chemical biology.

DNA sequence dependent binding modes of 4',6-diamidino-2-phenylindole (DAPI).

R. L. Jones, L. Strekowski,, W. Wilson, 1990, Biochemistry.

Cg Base Pair Recognition Within Dna Triple Helices Using N -Methyl-3 H -Pyrrolo[2,3- d ]Pyrimidin-2(7 H )-One Nucleoside Analogues

T. Brown, K. Fox, N. Srinivasan, 2007, Nucleosides, nucleotides & nucleic acids.

Towards the Targeted Modulation of Gene Expression by Modified Triplex-Forming Oligonucleotides

David A Rusling, T. Brown, K. Fox, 2008 .

Sequence-specific binding of luzopeptin to DNA.

M. Waring, J. Portugal, K. Fox, 1988, Nucleic acids research.