R. Cupples

发表

Molecular characterization of ALK, a receptor tyrosine kinase expressed specifically in the nervous system

T. Arakawa, S. Mori, Tadashi Yamamoto, 1997, Oncogene.

Discovery of 2,4-bis-arylamino-1,3-pyrimidines as insulin-like growth factor-1 receptor (IGF-1R) inhibitors.

David P. Carney, P. Gallant, M. Morrison, 2011, Bioorganic & medicinal chemistry letters.

Discovery of a potent, orally active 11beta-hydroxysteroid dehydrogenase type 1 inhibitor for clinical study: identification of (S)-2-((1S,2S,4R)-bicyclo[2.2.1]heptan-2-ylamino)-5-isopropyl-5-methylthiazol-4(5H)-one (AMG 221).

Jiandong Zhang, R. Syed, R. Hungate, 2010, Journal of medicinal chemistry.

Discovery and Structure-Guided Optimization of Diarylmethanesulfonamide Disrupters of Glucokinase-Glucokinase Regulatory Protein (GK-GKRP) Binding: Strategic Use of a N → S (nN → σ*S-X) Interaction for Conformational Constraint.

Kristin L. Andrews, Jiandong Zhang, S. Chmait, 2015, Journal of medicinal chemistry.

Further studies with the 2-amino-1,3-thiazol-4(5H)-one class of 11beta-hydroxysteroid dehydrogenase type 1 inhibitors: reducing pregnane X receptor activity and exploring activity in a monkey pharmacodynamic model.

Jiandong Zhang, R. Hungate, M. Véniant, 2008, Journal of medicinal chemistry.

Isolation, characterization, and expression of a cDNA encoding N-acetylglucosaminyltransferase V.

D. Wen, J. Weinstein, J. Browne, 1993, The Journal of biological chemistry.

Structural and functional aspects of the multiplicity of Neu differentiation factors

V. L. Jacobsen, D. Karunagaran, S. Suggs, 1994 .

Structural and Functional Aspects of the Multiplicity of Neu

Luo, Lu, Sylvia, 2022 .

Small molecule disruptors of the glucokinase-glucokinase regulatory protein interaction: 4. Exploration of a novel binding pocket.

S. Chmait, M. Bartberger, S. Jordan, 2014, Journal of medicinal chemistry.

Small molecule disruptors of the glucokinase-glucokinase regulatory protein interaction: 2. Leveraging structure-based drug design to identify analogues with improved pharmacokinetic profiles.

R. Kunz, Jiandong Zhang, S. Chmait, 2014, Journal of medicinal chemistry.

Human group-specific component (Gc) is a member of the albumin family.

S. Naylor, F. Yang, B. Bowman, 1985, Proceedings of the National Academy of Sciences of the United States of America.

Evolutionary and structural relationships among the group-specific component, albumin and alpha-fetoprotein.

R. McAnelly, F. Yang, B. Bowman, 1985, Nucleic acids research.

Structural and functional aspects of the multiplicity of Neu differentiation factors.

V. L. Jacobsen, D. Karunagaran, S. Suggs, 1994, Molecular and cellular biology.

Structural Characterization and Pharmacodynamic Effects of an Orally Active 11β‐Hydroxysteroid Dehydrogenase Type 1 Inhibitor

Zhulun Wang, Haoda Xu, Xiaoshan Min, 2007, Chemical biology & drug design.

The discovery of 2-anilinothiazolones as 11beta-HSD1 inhibitors.

Jiandong Zhang, R. Hungate, Meredith Williams, 2007, Bioorganic & medicinal chemistry letters.

Human ceruloplasmin. Tissue-specific expression of transcripts produced by alternative splicing.

W. Friedrichs, M. Bonifácio, W. Horton, 1990, The Journal of biological chemistry.

Neu differentiation factor: A transmembrane glycoprotein containing an EGF domain and an immunoglobulin homology unit

R. Koski, Y. Yarden, E. Peles, 1992, Cell.

Small Molecule Disruptors of the Glucokinase-Glucokinase Regulatory Protein Interaction: 5. A Novel Aryl Sulfone Series, Optimization Through Conformational Analysis.

S. Chmait, M. Bartberger, S. Jordan, 2015, Journal of medicinal chemistry.

2-(S)-phenethylaminothiazolones as potent, orally efficacious inhibitors of 11beta-hydroxysteriod dehydrogenase type 1.

R. Hungate, M. Véniant, Minghan Wang, 2007, Journal of medicinal chemistry.

Primary structure and functional expression of rat and human stem cell factor DNAs

K. Zsebo, J. Wypych, S. Suggs, 1990, Cell.

Small molecule disruptors of the glucokinase-glucokinase regulatory protein interaction: 3. Structure-activity relationships within the aryl carbinol region of the N-arylsulfonamido-N'-arylpiperazine series.

R. Kunz, S. Chmait, M. Bartberger, 2014, Journal of medicinal chemistry.

GDNF–Induced Activation of the Ret Protein Tyrosine Kinase Is Mediated by GDNFR-α, a Novel Receptor for GDNF

J. Louis, G. M. Fox, Yi Luo, 1996, Cell.

Small molecule disruptors of the glucokinase-glucokinase regulatory protein interaction: 1. Discovery of a novel tool compound for in vivo proof-of-concept.

R. Wahl, Jiandong Zhang, S. Chmait, 2014, Journal of medicinal chemistry.

Antidiabetic effects of glucokinase regulatory protein small-molecule disruptors

R. Wahl, Jiandong Zhang, S. Chmait, 2013, Nature.

Cloning and Characterization of a Specific Receptor for Mouse Oncostatin M

R. Lindberg, A. Welcher, R. Cupples, 1998, Molecular and Cellular Biology.

Yu Receptor for Mouse Oncostatin M Cloning and Characterization of a Specific

R. Lindberg, A. Welcher, R. Cupples, 1998 .

Human alpha 2-HS-glycoprotein/bovine fetuin homologue in mice: identification and developmental regulation of the gene.

W. Friedrichs, J. Bergeron, F. Yang, 1992, Biochimica et biophysica acta.

Cloning of cDNAs encoding human TIMP-3, a novel member of the tissue inhibitor of metalloproteinase family.

R. Koski, V. L. Jacobsen, R. Cupples, 1994, Gene.

Structural and functional aspects of the multiplicity of Neu differentiation factors

V. L. Jacobsen, D. Karunagaran, S. Suggs, 1994, Molecular and cellular biology.