Dayong Shi

发表

Highly E-Selective Synthesis of α-Fluoro-β-arylalkenyl Sulfones from gem-Difluoroalkenes with Sodium Sulfinates.

Xiangqian Li, Yuxiu Li, Xiaowei Li, 2021, The Journal of organic chemistry.

Recent progress of the development of dipeptidyl peptidase-4 inhibitors for the treatment of type 2 diabetes mellitus.

Xiangqian Li, B. Jiang, Dayong Shi, 2018, European journal of medicinal chemistry.

Antidiabetic activity in vitro and in vivo of BDB, a selective inhibitor of protein tyrosine phosphatase 1B, from Rhodomela confervoides

Meiling Zheng, Xiangqian Li, B. Jiang, 2020, British Journal of Pharmacology.

The Fluoro-Thiazolylhydrazone Compound TSC-3C Inhibits Triple Negative Breast Cancer (TNBC) Cell Line Activity by Promoting Apoptosis, Regulating the MAPK Pathway and Inducing Mitochondrial Dysfunction

Dayong Shi, Shuju Guo, Jiajia Zhang, 2020, International journal of molecular sciences.

BOS-93, a novel bromophenol derivative, induces apoptosis and autophagy in human A549 lung cancer cells via PI3K/Akt/mTOR and MAPK signaling pathway

B. Jiang, Dayong Shi, Jiao Luo, 2019, Experimental and therapeutic medicine.

Highly Selective Protein Tyrosine Phosphatase Inhibitor, 2,2',3,3'-Tetrabromo-4,4',5,5'-tetrahydroxydiphenylmethane, Ameliorates Type 2 Diabetes Mellitus in BKS db Mice.

C. Li, Xiangqian Li, Dayong Shi, 2019, Molecular pharmaceutics.

Selectivity, cell permeability and oral availability studies of novel bromophenol derivative HPN as protein tyrosine phosphatase 1B inhibitor

Xiangqian Li, B. Jiang, Dayong Shi, 2017, British journal of pharmacology.

Discovery of Natural Dimeric Naphthopyrones as Potential Cytotoxic Agents through ROS-Mediated Apoptotic Pathway

Dayong Shi, Chuanlong Guo, Shuju Guo, 2019, Marine drugs.

Total synthesis of bis-(2,3-dibromo-4,5-dihydroxyphenyl)-methane as potent PTP1B inhibitor

Lijun Han, Hua Su, Dayong Shi, 2008 .

Natural and semisynthetic protein tyrosine phosphatase 1B (PTP1B) inhibitors as anti-diabetic agents

B. Jiang, Dayong Shi, Li-Jun Wang, 2015 .

Marine Bromophenol Derivative 3,4-Dibromo-5-(2-bromo-3,4-dihydroxy-6-isopropoxymethyl benzyl)benzene-1,2-diol Protects Hepatocytes from Lipid-Induced Cell Damage and Insulin Resistance via PTP1B Inhibition

Xiangqian Li, B. Jiang, Dayong Shi, 2015, Marine drugs.

CYC31, A Natural Bromophenol PTP1B Inhibitor, Activates Insulin Signaling and Improves Long Chain-Fatty Acid Oxidation in C2C12 Myotubes

B. Jiang, Dayong Shi, Jiao Luo, 2020, Marine drugs.

Design, synthesis and biological evaluation of novel pyrimidinedione derivatives as DPP-4 inhibitors.

C. Li, Xiangqian Li, B. Jiang, 2018, Bioorganic & medicinal chemistry letters.

A Unified Approach for Divergent Synthesis of Heterocycles via TMSOTf‐Catalyzed Formal [3+2] Cycloaddition of Electron‐Rich Alkynes

Xiangqian Li, Dayong Shi, Ping-Fan Chen, 2021, Advanced Synthesis & Catalysis.

Design, Synthesis, and Biological Evaluation of Bromophenol Derivatives as Protein Tyrosine Phosphatase 1B Inhibitors

B. Jiang, Dayong Shi, Shuju Guo, 2012, Archiv der Pharmazie.

Bromophenols as inhibitors of protein tyrosine phosphatase 1B with antidiabetic properties.

Hua Su, B. Jiang, Dayong Shi, 2012, Bioorganic & medicinal chemistry letters.

Synthesis and protein tyrosine phosphatase 1B inhibition activities of two new synthetic bromophenols and their methoxy derivatives

Dayong Shi, Zhiqiang Hu, Yongchao Cui, 2011 .

Synthesis of three bromophenols from red algae as PTP1B inhibitors

Lijun Han, Ting Li, Dayong Shi, 2011 .

Visible-light-promoted E-selective synthesis of α-fluoro-β-arylalkenyl sulfides via the deoxygenation/isomerization process.

Xiangqian Li, Yuxiu Li, Xiaowei Li, 2021, Chemical communications.

Ligand- and Additive-Free 2-Position-Selective Trifluoromethylation of Heteroarenes Under Ambient Conditions

Xiangqian Li, Xiaowei Li, Dayong Shi, 2019, Front. Chem..

Halogenated Compounds from Corals: Chemical Diversity and Biological Activities.

Yuanyuan Zhang, Junhong Liu, Dayong Shi, 2018, Mini reviews in medicinal chemistry.

Visible‐Light‐Promoted Oxy‐difluoroalkylation of Aryl Alkynes for the Synthesis of β ‐Fluoroenones and α ‐Difluoroalkyl Ketones

Xiangqian Li, Dayong Shi, Zhong Zhang, 2021 .

BPN, a marine-derived PTP1B inhibitor, activates insulin signaling and improves insulin resistance in C2C12 myotubes.

Dayong Shi, Jiao Luo, Renshuai Zhang, 2018, International journal of biological macromolecules.

Chalcone-analogue fluorescent probes for detecting thiophenols in seawater samples.

Junting Fan, Dayong Shi, Chuanlong Guo, 2019, Talanta.

Design and Synthesis of a Fluorescent Probe with a Large Stokes Shift for Detecting Thiophenols and Its Application in Water Samples and Living Cells

Dayong Shi, Chuanlong Guo, Shuju Guo, 2019, Molecules.

An UHPLC-TOF-MS method for quantifying novel brominated anticancer compound bromophenol-thiosemicarbazone hybrid and its application to in vivo pharmacokinetic study

Dayong Shi, Chuanlong Guo, Lijun Wang, 2020, Journal of Analytical Science and Technology.

Zinc-doped copper oxide nanocomposites reverse temozolomide resistance in glioblastoma by inhibiting AKT and ERK1/2.

Xiukun Lin, A. Gedanken, Dayong Shi, 2018, Nanomedicine.

Inhibitor binding sites in the protein tyrosine phosphatase SHP-2.

C. Meng, Zhengquan Gao, Xiangqian Li, 2020, Mini reviews in medicinal chemistry.

Bromophenol curcumin analog BCA-5 exerts an antiangiogenic effect through the HIF-1&agr;/VEGF/Akt signaling pathway in human umbilical vein endothelial cells

B. Jiang, Dayong Shi, Lijun Wang, 2018, Anti-cancer drugs.

Bromophenol derivatives from algae, novel inhibitors of PTP1B as potential agents for treatment of T2DM

Lijun Han, Feng Xu, Dayong Shi, 2008 .

Inhibition of bromophenols against PTP1B and anti-hyperglycemic effect of Rhodomela confervoides extract in diabetic rats

Lijun Han, Dayong Shi, Juan He, 2008 .

Discovery of Novel Bromophenol-Thiosemicarbazone Hybrids as Potent Selective Inhibitors of Poly(ADP-ribose) Polymerase-1 (PARP-1) for Use in Cancer.

Xiangqian Li, B. Jiang, Dayong Shi, 2019, Journal of medicinal chemistry.

Marine Bromophenol Bis (2,3-Dibromo-4,5-dihydroxy-phenyl)-methane Inhibits the Proliferation, Migration, and Invasion of Hepatocellular Carcinoma Cells via Modulating β1-Integrin/FAK Signaling

Jian Li, B. Jiang, Dayong Shi, 2015, Marine drugs.

Anti-Angiogenic Properties of BDDPM, a Bromophenol from Marine Red Alga Rhodomela confervoides, with Multi Receptor Tyrosine Kinase Inhibition Effects

Xiangqian Li, B. Jiang, Dayong Shi, 2015, International journal of molecular sciences.

Cu(II)-Catalyzed Oxidative Trifluoromethylation of Indoles with KF as the Base

Xiaowei Li, Dayong Shi, Lina Ma, 2019, Catalysts.

Iron-catalyzed alkynylation of tertiary aliphatic amines with 1-iodoalkynes to synthesize propargylamines

Xiaowei Li, Dayong Shi, Lina Ma, 2018 .

Visible light–initiated radical 1,3-difunctionalization of β,γ-unsaturated ketones

Xiangqian Li, Chenyang Zhao, Dayong Shi, 2022, Science advances.

BTH-8, a novel poly (ADP-ribose) polymerase-1 (PARP-1) inhibitor, causes DNA double-strand breaks and exhibits anticancer activities in vitro and in vivo.

Xiaochen Wu, Dayong Shi, Xiaochen A. Wu, 2020, International journal of biological macromolecules.

AcOH-mediated aerobic oxidative synthesis of 2-thioalkylbenzothiazoles via a three-component reaction

Xiangqian Li, Yuxiu Li, Xiaowei Li, 2020, Tetrahedron Letters.

A New Furanone Isolated from a Marine-Derived Actinomycete M159

Xiancui Li, Hua Su, Dayong Shi, 2015, Chemistry of Natural Compounds.

Nickel-Catalyzed Stereoselective Cascade C–F Functionalizations of gem-Difluoroalkenes

Xiangqian Li, Hongyun Qin, Yuxiu Li, 2023, ACS Catalysis.

Design, synthesis and biological evaluation of uncharged catechol derivatives as selective inhibitors of PTP1B.

Xiangqian Li, B. Jiang, Dayong Shi, 2017, European journal of medicinal chemistry.

Nickel-Catalyzed Arylation of C(sp3)-O Bonds in Allylic Alkyl Ethers with Organoboron Compounds.

Xiangqian Li, Yuxiu Li, Xiaowei Li, 2021, Organic letters.

Design, Synthesis and Biological Evaluation of Novel Bromophenol Derivatives Incorporating Indolin-2-One Moiety as Potential Anticancer Agents

Xiangqian Li, Meng Yang, B. Jiang, 2015, Marine drugs.

Sesquiterpenes from the red alga Laurencia tristicha.

Lijun Han, Dayong Shi, Shuai Li, 2005, Journal of natural products.

Steroids from green alga Chaetomorpha basiretorsa Setchell

Lijun Han, Dayong Shi, Jiangong Shi, 2008 .

A new ketosteroid from red alga Acanthophora spicifera

Dayong Shi, Shuju Guo, Xiaoli Fan, 2011 .

Chemical constituents of the red alga Laurencia tristicha

Lijun Han, Dayong Shi, Shuai Li, 2007, Journal of Asian natural products research.

Baicalein-loaded silk fibroin peptide nanofibers protect against cisplatin-induced acute kidney injury: fabrication, characterization and mechanism.

Xiaochen Wu, Xianghui Qi, Dayong Shi, 2022, International journal of pharmaceutics.

Fucoidan-ferulic acid nanoparticles alleviate cisplatin-induced acute kidney injury by inhibiting the cGAS-STING pathway.

Xiaochen Wu, Fanye Wang, Dayong Shi, 2022, International journal of biological macromolecules.

Rational Multitargeted Drug Design Strategy from the Perspective of a Medicinal Chemist.

S. Li, F. Liu, Xiangqian Li, 2021, Journal of medicinal chemistry.

Discovery of novel bromophenol 3,4-dibromo-5-(2-bromo-3,4-dihydroxy-6-(isobutoxymethyl)benzyl)benzene-1,2-diol as protein tyrosine phosphatase 1B inhibitor and its anti-diabetic properties in C57BL/KsJ-db/db mice.

Chaohong Guo, B. Jiang, Dayong Shi, 2013, European journal of medicinal chemistry.

Small molecules as potent protein tyrosine phosphatase 1B (PTP1B) inhibitors documented in patents from 2009 to 2013.

B. Jiang, Dayong Shi, Li-Jun Wang, 2015, Mini reviews in medicinal chemistry.

The chemical constituents from red alga Gymnogongrus flabelliformis Harv.

Lijun Han, Hua Su, Dayong Shi, 2008 .

Recent advances in transition-metal-catalyzed incorporation of fluorine-containing groups

Xiangqian Li, Xiaowei Li, Dayong Shi, 2019, Beilstein journal of organic chemistry.

Application of Fluorine in Drug Design During 2010-2015 Years: A Mini-Review.

Xiangqian Li, B. Jiang, Dayong Shi, 2017, Mini-Reviews in Medical Chemistry.

A novel fluorinated thiosemicarbazone derivative- 2-(3,4-difluorobenzylidene) hydrazinecarbothioamide induces apoptosis in human A549 lung cancer cells via ROS-mediated mitochondria-dependent pathway.

Xiangqian Li, B. Jiang, Dayong Shi, 2017, Biochemical and biophysical research communications.

A review of the components of brown seaweeds as potential candidates in cancer therapy

E. Hussain, G. Butt, B. Jiang, 2016 .

Cardamonin induces apoptosis by suppressing STAT3 signaling pathway in glioblastoma stem cells

B. Jiang, Xiukun Lin, Jia Liu, 2015, Tumor Biology.

Structural and Bioactive Studies of Halogenated Constituents from Sponges.

Dayong Shi, Chao Li, 2020, Current medicinal chemistry.

A Novel Bromophenol Derivative BOS-102 Induces Cell Cycle Arrest and Apoptosis in Human A549 Lung Cancer Cells via ROS-Mediated PI3K/Akt and the MAPK Signaling Pathway

Xiangqian Li, B. Jiang, Dayong Shi, 2018, Marine drugs.

Sesquiterpenes from the Marine Red Alga Laurencia saitoi

Lijun Han, Xiaobing Zhu, L. Deng, 2009 .

16S rRNA Sequencing and Metagenomics Study of Gut Microbiota: Implications of BDB on Type 2 Diabetes Mellitus

Xiangqian Li, Dayong Shi, Jiao Luo, 2020, Marine drugs.

[Studies on chemical constituents of Laurencia saitoi].

Lijun Han, Xiaobing Zhu, Hua Su, 2009, Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica.

[Studies on chemical constituents of Laurencia tristicha ( II )].

Lijun Han, Dayong Shi, Jiangong Shi, 2007, Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica.

Two new bromoindoles from red alga Laurencia similis

Lijun Han, L. Deng, Hua Su, 2009 .

Design of antitumor agents containing carbohydrate based on GLUT1, and evaluation of antiproliferative activity.

B. Jiang, Dayong Shi, Renshuai Zhang, 2017, Bioorganic & medicinal chemistry letters.

The antitumor effect of bromophenol derivatives in vitro and Leathesia nana extract in vivo

Hua Su, Dayong Shi, Shuju Guo, 2009 .

Myricetin-Loaded Nanomicelles Protect against Cisplatin-Induced Acute Kidney Injury by Inhibiting the DNA Damage-cGAS-STING Signaling Pathway.

Xiaochen Wu, Xianghui Qi, Dayong Shi, 2022, Molecular pharmaceutics.

The design strategy of selective PTP1B inhibitors over TCPTP.

Xiangqian Li, Dayong Shi, XiangQian Li, 2016, Bioorganic & medicinal chemistry.

HPN, a Synthetic Analogue of Bromophenol from Red Alga Rhodomela confervoides: Synthesis and Anti-Diabetic Effects in C57BL/KsJ-db/db Mice

Luyong Zhang, Chaohong Guo, B. Jiang, 2013, Marine drugs.

Inhibition of PTP1B blocks pancreatic cancer progression by targeting the PKM2/AMPK/mTOC1 pathway

Huaizhi Wang, Xiangqian Li, B. Jiang, 2019, Cell Death & Disease.

Phytochemical and chemotaxonomic study on Leathesia nana (Chordariaceae)

Xiang Li, Dayong Shi, Shuju Guo, 2018, Biochemical Systematics and Ecology.

Pterostilbene-Loaded Soluplus/Poloxamer 188 Mixed Micelles for Protection against Acetaminophen-Induced Acute Liver Injury.

Y. Liu, Xiaochen Wu, Mei Zhang, 2023, Molecular pharmaceutics.

Silk fibroin peptide self-assembled nanofibers delivered naringenin to alleviate cisplatin-induced acute kidney injury by inhibiting mtDNA-cGAS-STING pathway.

Xiaochen Wu, Dayong Shi, Chuan-Yong Guo, 2023, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.

Discovery of Novel Bromophenol Hybrids as Potential Anticancer Agents through the Ros-Mediated Apoptotic Pathway: Design, Synthesis and Biological Evaluation

Xiangqian Li, B. Jiang, Dayong Shi, 2017, Marine Drugs.

Design, synthesis and biological evaluation of bromophenol-thiazolylhydrazone hybrids inhibiting the interaction of translation initiation factors eIF4E/eIF4G as multifunctional agents for cancer treatment.

C. Li, Xiangqian Li, B. Jiang, 2019, European journal of medicinal chemistry.

Synthesis and biological evaluation of novel fluorinated anticancer agents incorporating the indolin-2-one moiety

Xiangqian Li, B. Jiang, Dayong Shi, 2015 .

[PTP1B inhibitory activities of bromophenol derivatives from algae].

Lijun Han, Hua Su, Dayong Shi, 2008, Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica.

Toward a treatment of diabesity: In vitro and in vivo evaluation of uncharged bromophenol derivatives as a new series of PTP1B inhibitors.

C. Li, Xiangqian Li, B. Jiang, 2019, European journal of medicinal chemistry.

Discovery and evaluation of the hybrid of bromophenol and saccharide as potent and selective protein tyrosine phosphatase 1B inhibitors.

Xiangqian Li, B. Jiang, Dayong Shi, 2017, European journal of medicinal chemistry.

CYC27 Synthetic Derivative of Bromophenol from Red Alga Rhodomela confervoides: Anti-Diabetic Effects of Sensitizing Insulin Signaling Pathways and Modulating RNA Splicing-Associated RBPs

B. Jiang, Dayong Shi, Jiao Luo, 2019, Marine drugs.

Design of antitumor agents containing carbohydrate based on GLUT1, and evaluation of antiproliferative activity.

B. Jiang, Dayong Shi, Renshuai Zhang, 2017, Bioorganic & medicinal chemistry letters.