J. Farand

发表

Discovery of Potent and Selective MTH1 Inhibitors for Oncology: Enabling Rapid Target (In)Validation.

S. Viatchenko‐Karpinski, J. Sudhamsu, Xiaowu Chen, 2019, ACS medicinal chemistry letters.

Sequence confirmation of modified oligonucleotides using chemical degradation, electrospray ionization, time-of-flight, and tandem mass spectrometry.

J. Farand, M. Beverly, 2008, Analytical chemistry.

De novo sequence determination of modified oligonucleotides.

F. Gosselin, J. Farand, 2009, Analytical chemistry.

Characterization of a KDM5 Small Molecule Inhibitor with Antiviral Activity against Hepatitis B Virus

Gregg A. Czerwieniec, Helen Yu, T. Appleby, 2022, bioRxiv.

Selectivity switch between FAK and Pyk2: Macrocyclization of FAK inhibitors improves Pyk2 potency.

J. Chandrasekhar, G. Phillips, R. Mourey, 2016, Bioorganic & medicinal chemistry letters.

Characterization of a KDM5 small molecule inhibitor with antiviral activity against hepatitis B virus

Gregg A. Czerwieniec, Helen Yu, T. Appleby, 2022, bioRxiv.

Naphthalene/quinoline amides and sulfonylureas as potent and selective antagonists of the EP4 receptor.

P. Clark, Steve Rowland, D. Denis, 2011, Bioorganic & medicinal chemistry letters.

Progress toward the total synthesis of (±)-havellockate.

J. Farand, Rachel L. Beingessner, L. Barriault, 2010, The Journal of organic chemistry.

Structure-activity relationships and pharmacokinetic parameters of quinoline acylsulfonamides as potent and selective antagonists of the EP(4) receptor.

P. Clark, Steve Rowland, D. Denis, 2008, Bioorganic & medicinal chemistry letters.

The discovery of 4-{1-[({2,5-dimethyl-4-[4-(trifluoromethyl)benzyl]-3-thienyl}carbonyl)amino]cyclopropyl}benzoic acid (MK-2894), a potent and selective prostaglandin E2 subtype 4 receptor antagonist.

P. Clark, Steve Rowland, D. Denis, 2010, Journal of medicinal chemistry.

In vivo pharmacodynamics of GS-5801, a liver targeted prodrug of a lysine demethylase 5 inhibitor with antiviral activity against hepatitis B virus

W. Delaney, B. Feierbach, C. Snyder, 2017 .

Improving the in vivo therapeutic index of siRNA polymer conjugates through increasing pH responsiveness.

L. Sepp-Lorenzino, I. Davies, B. Howell, 2014, Bioconjugate chemistry.