E. Murakami

G. Kajiyama, H. Imagawa, H. Okanobu, 2008, Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver.

Abatacept treatment for patients with severe acute hepatitis caused by hepatitis B virus infection—Pilot study

M. Imamura, K. Chayama, D. Miki, 2020, Journal of viral hepatitis.

A novel TK-NOG based humanized mouse model for the study of HBV and HCV infections.

M. Imamura, N. Hiraga, K. Chayama, 2013, Biochemical and biophysical research communications.

Non‐invasive liver fibrosis score calculated by combination of virtual touch tissue quantification and serum liver functional tests in chronic hepatitis C patients

M. Imamura, N. Hiraga, K. Chayama, 2014, Hepatology research : the official journal of the Japan Society of Hepatology.

A case with life-threatening secondary sclerosing cholangitis caused by nivolumab

M. Imamura, K. Chayama, N. Hattori, 2020, Clinical Journal of Gastroenterology.

Evidence for Intersubunit Communication during Acetyl-CoA Cleavage by the Multienzyme CO Dehydrogenase/Acetyl-CoA Synthase Complex from Methanosarcina thermophila

S. Ragsdale, E. Murakami, 2000, The Journal of Biological Chemistry.

Bifunctional inhibition of HIV-1 reverse transcriptase: a first step in designing a bifunctional triphosphate.

W. Hinz, K. Anderson, D. Austin, 2013, Bioorganic & medicinal chemistry letters.

Inhibition of Hepatitis C Virus Replicon RNA Synthesis by PSI-352938, a Cyclic Phosphate Prodrug of β-d-2′-Deoxy-2′-α-Fluoro-2′-β-C-Methylguanosine

M. Otto, C. Espiritu, A. Lam, 2011, Antimicrobial Agents and Chemotherapy.

Inhibition of Hepatitis C Virus Replicon RNA Synthesis by PSI-352938, a Cyclic Phosphate Prodrug of (cid:1) - D -2 (cid:2) -Deoxy-2 (cid:2) - (cid:3) -Fluoro-2 (cid:2) - (cid:1) - C -Methylguanosine (cid:1) †

M. Otto, C. Espiritu, A. Lam, 2011 .

Evaluation of the in vitro anti-HBV activity of clevudine in combination with other nucleoside/ nucleotide inhibitors

T. Tolstykh, Haiying Bao, E. Murakami, 2010, Antiviral therapy.

The presence of vessels encapsulating tumor clusters is associated with an immunosuppressive tumor microenvironment in hepatocellular carcinoma

M. Imamura, K. Chayama, K. Arihiro, 2022, International journal of cancer.

PSI-7851, a Pronucleotide of (cid:1) - D -2 (cid:2) -Deoxy-2 (cid:2) -Fluoro-2 (cid:2) - C -Methyluridine Monophosphate, Is a Potent and Pan-Genotype Inhibitor of Hepatitis C Virus Replication (cid:1)

M. Otto, D. Smee, C. Espiritu, 2010 .

K. Awai, M. Imamura, K. Chayama, 2021, BMC Gastroenterology.

Construction of an anti-hepatitis B virus preS1 antibody and usefulness of preS1 measurement for chronic hepatitis B patients

M. Imamura, K. Chayama, Shinji Tanaka, 2021, Journal of Infection.

The effect of the skin–liver capsule distance on the accuracy of ultrasound diagnosis for liver steatosis and fibrosis

M. Imamura, D. Miki, H. Aikata, 2022, Journal of Medical Ultrasonics.

Multicentric hepatocarcinogenesis at 6 and 13 years after sustained viral response to hepatitis C virus

M. Imamura, N. Hiraga, K. Chayama, 2012, Clinical Journal of Gastroenterology.

Adenosine deaminase-like protein 1 (ADAL1): characterization and substrate specificity in the hydrolysis of N(6)- or O(6)-substituted purine or 2-aminopurine nucleoside monophosphates.

M. Sofia, R. Mosley, Haiying Bao, 2011, Journal of medicinal chemistry.

Interaction of 2′-deoxyguanosine Triphosphate Analogue Inhibitors of HIV Reverse Transcriptase with Human Mitochondrial DNA Polymerase γ

K. Anderson, R. Schinazi, C. K. Chu, 2007, Antiviral chemistry & chemotherapy.

Mechanism of Anti-Human Immunodeﬁciency Virus Activity of (cid:2) - D -6-Cyclopropylamino-2 (cid:3) ,3 (cid:3) -Didehydro-2 (cid:3) ,3 (cid:3) -Dideoxyguanosine

K. Anderson, R. Schinazi, C. K. Chu, 2005 .

Evaluation of atezolizumab plus bevacizumab combination therapy for hepatocellular carcinoma using contrast-enhanced ultrasonography

M. Imamura, D. Miki, H. Aikata, 2022, Journal of Medical Ultrasonics.

Advanced hepatocellular carcinoma with response to lenvatinib after atezolizumab plus bevacizumab

M. Imamura, H. Ohdan, H. Aikata, 2021, Medicine.

Three Children Treated with Direct-acting Antivirals for Chronic Hepatitis C Virus Genotype 1b Infection

M. Imamura, K. Chayama, H. Aikata, 2019, Internal medicine.

Mechanism of Activation of PSI-7851 and Its Diastereoisomer PSI-7977

M. Otto, C. Espiritu, A. Lam, 2010, The Journal of Biological Chemistry.

Hepatitis B infection derived from a donor and de novo autoimmune hepatitis subsequent to pegylated-interferon treatment for recurrent hepatitis C after living-liver transplantation: A case report

M. Imamura, K. Chayama, H. Aikata, 2014 .

Discovery of a 2'-fluoro-2'-C-methyl C-nucleotide HCV polymerase inhibitor and a phosphoramidate prodrug with favorable properties.

Huiling Yang, T. Appleby, M. Fenaux, 2017, Bioorganic & medicinal chemistry letters.

Mechanism of action of a novel viral mutagenic covert nucleotide: molecular interactions with HIV-1 reverse transcriptase and host cell DNA polymerases.

K. Anderson, A. Basavapathruni, E. Murakami, 2005, Antiviral research.

Investigating the effects of stereochemistry on incorporation and removal of 5-fluorocytidine analogs by mitochondrial DNA polymerase gamma: comparison of D- and L-D4FC-TP.

K. Anderson, R. Schinazi, A. Ray, 2004, Antiviral research.

Characterization of Novel Reverse Transcriptase and Other RNA-associated Catalytic Activities by Human DNA Polymerase γ

K. Anderson, Kenneth A. Johnson, Joy Y. Feng, 2003, Journal of Biological Chemistry.

Activity and the metabolic activation pathway of the potent and selective hepatitis C virus pronucleotide inhibitor PSI-353661.

M. Otto, C. Espiritu, A. Lam, 2011, Antiviral research.

Effect of tenofovir disoproxil fumarate on drug-resistant HBV clones.

M. Imamura, N. Hiraga, K. Chayama, 2016, The Journal of infection.

Implications of Efficient Hepatic Delivery by Tenofovir Alafenamide (GS-7340) for Hepatitis B Virus Therapy

A. Ray, Yeojin Park, D. Babusis, 2015, Antimicrobial Agents and Chemotherapy.

Species differences in liver accumulation and metabolism of nucleotide prodrug sofosbuvir.

A. Ray, Yeojin Park, D. Babusis, 2020, Drug Metabolism and Pharmacokinetics.

The Association between Serum Cytokine and Chemokine Levels and Antiviral Response by Entecavir Treatment in Chronic Hepatitis B Patients

M. Imamura, K. Chayama, D. Miki, 2018, Antiviral therapy.

Reduction of hepatitis B surface antigen in sequential versus add-on pegylated interferon to nucleoside/nucleotide analogue therapy in HBe-antigen-negative chronic hepatitis B patients: A pilot study

M. Imamura, K. Chayama, D. Miki, 2018, Antiviral therapy.

Serum HBV RNA and HBeAg are useful markers for the safe discontinuation of nucleotide analogue treatments in chronic hepatitis B patients

M. Imamura, N. Hiraga, K. Chayama, 2013, Journal of Gastroenterology.

Remdesivir potently inhibits SARS-CoV-2 in human lung cells and chimeric SARS-CoV expressing the SARS-CoV-2 RNA polymerase in mice

Xiaotao Lu, Alexandra Schäfer, Ralph S. Baric, 2020, bioRxiv.

Clinical study of the pressure dressing therapy for parotid salivary fistulas and sialoceles

Seiji Nakamura, M. Oka, M. Shinohara, 1984 .

Characterization of the Intramolecular Electron Transfer Pathway from 2-Hydroxyphenazine to the Heterodisulfide Reductase fromMethanosarcina thermophila *

S. Ragsdale, U. Deppenmeier, E. Murakami, 2001, The Journal of Biological Chemistry.

Isolated cardiac metastases of hepatocellular carcinoma after resection: a case report

M. Imamura, K. Chayama, T. Kimura, 2019, Clinical Journal of Gastroenterology.

The mechanism of action of beta-D-2'-deoxy-2'-fluoro-2'-C-methylcytidine involves a second metabolic pathway leading to beta-D-2'-deoxy-2'-fluoro-2'-C-methyluridine 5'-triphosphate, a potent inhibitor of the hepatitis C virus RNA-dependent RNA polymerase.

M. Otto, Haiying Bao, E. Murakami, 2008, Antimicrobial agents and chemotherapy.

Clevudine is Efficiently Phosphorylated to the Active Triphosphate form in Primary Human Hepatocytes

E. Murakami, C. Niu, P. Furman, 2008, Antiviral therapy.

Use of 2'-spirocyclic ethers in HCV nucleoside design.

C. Espiritu, A. Lam, M. Sofia, 2014, Journal of medicinal chemistry.

Probing the molecular mechanisms of AZT drug resistance mediated by HIV-1 reverse transcriptase using a transient kinetic analysis.

K. Anderson, R. Schinazi, C. K. Chu, 2003, Biochemistry.

Noncompetitive Inhibition of Hepatitis B Virus Reverse Transcriptase Protein Priming and DNA Synthesis by the Nucleoside Analog Clevudine

Scott A. Jones, W. Delaney, Jianming Hu, 2013, Antimicrobial Agents and Chemotherapy.

Mechanism of Anti-Human Immunodeficiency Virus Activity of β-d-6-Cyclopropylamino-2′,3′-Didehydro-2′,3′-Dideoxyguanosine

K. Anderson, H. McClure, R. Schinazi, 2005, Antimicrobial Agents and Chemotherapy.

Probing the Mechanistic Consequences of 5-Fluorine Substitution on Cytidine Nucleotide Analogue Incorporation by HIV-1 Reverse Transcriptase

K. Anderson, R. Schinazi, C. K. Chu, 2003, Antiviral chemistry & chemotherapy.

Synthesis and anti-HCV activity of 3',4'-oxetane nucleosides.

M. Otto, M. Sofia, B. Ross, 2010, Bioorganic & medicinal chemistry letters.

Interactions of enantiomers of 2',3'-didehydro-2',3'-dideoxy-fluorocytidine with wild type and M184V mutant HIV-1 reverse transcriptase.

K. Anderson, R. Schinazi, A. Ray, 2002, Antiviral research.

Structural basis for RNA replication by the hepatitis C virus polymerase

M. Mcgrath, T. Appleby, S. Swaminathan, 2015, Science.

A 2′-Deoxy-2′-Fluoro-2′-C-Methyl Uridine Cyclopentyl Carbocyclic Analog and Its Phosphoramidate Prodrug as Inhibitors of HCV NS5B Polymerase

C. Espiritu, M. Sofia, Jian Liu, 2012, Nucleosides, nucleotides & nucleic acids.

β-D-2'-α-F-2'-β-C-Methyl-6-O-substituted 3',5'-cyclic phosphate nucleotide prodrugs as inhibitors of hepatitis C virus replication: a structure-activity relationship study.

M. Otto, C. Espiritu, A. Lam, 2012, Bioorganic & medicinal chemistry letters.

Structure of Hepatitis C Virus Polymerase in Complex with Primer-Template RNA

M. Otto, A. Lam, M. Sofia, 2012, Journal of Virology.

[590] INHIBITION OF HCV REPLICATION BY PSI-6130: MECHANISM OF BIOCHEMICAL ACTIVATION AND INHIBITION

M. Otto, J. Symons, Haiying Bao, 2007 .

Endoplasmic reticulum-mediated induction of interleukin-8 occurs by hepatitis B virus infection and contributes to suppression of interferon responsiveness in human hepatocytes.

M. Imamura, N. Hiraga, K. Chayama, 2018, Virology.

Comparison of intracellular responses between HBV genotype A and C infection in human hepatocyte chimeric mice

M. Imamura, N. Hiraga, K. Chayama, 2019, Journal of Gastroenterology.

Ribavirin induces hepatitis C virus genome mutations in chronic hepatitis patients who failed to respond to prior daclatasvir plus asunaprevir therapy

M. Imamura, K. Chayama, D. Miki, 2020, Journal of medical virology.

Emergence of resistant variants detected by ultra‐deep sequencing after asunaprevir and daclatasvir combination therapy in patients infected with hepatitis C virus genotype 1

H Abe, M. Imamura, N. Hiraga, 2015, Journal of viral hepatitis.

Long term persistence of NS5A inhibitor‐resistant hepatitis C virus in patients who failed daclatasvir and asunaprevir therapy

M. Imamura, N. Hiraga, K. Chayama, 2015, Journal of medical virology.

Metabolic Activation of the Anti-Hepatitis C Virus Nucleotide Prodrug PSI-352938

M. Otto, A. Lam, M. Sofia, 2012, Antimicrobial Agents and Chemotherapy.

Molecular and Structural Basis for the Roles of Hepatitis C Virus Polymerase NS5B Amino Acids 15, 223, and 321 in Viral Replication and Drug Resistance

M. Otto, A. Lam, M. Sofia, 2014, Antimicrobial Agents and Chemotherapy.

Identification and monitoring of mutations in circulating cell-free tumor DNA in hepatocellular carcinoma treated with lenvatinib

M. Imamura, K. Chayama, D. Miki, 2021, Journal of Experimental & Clinical Cancer Research.

Purification and properties of the heme- and iron-sulfur-containing heterodisulfide reductase from Methanosarcina thermophila.

J. Brewer, S. Ragsdale, E. Murakami, 1998, Biochemistry.

Key Metabolic Enzymes Involved in Remdesivir Activation in Human Lung Cells

Xuping Xie, P. Shi, J. Bilello, 2021, Antimicrobial agents and chemotherapy.

The effects of bisphosphonate zoledronic acid in hepatocellular carcinoma, depending on mevalonate pathway

M. Imamura, N. Hiraga, K. Chayama, 2015, Journal of gastroenterology and hepatology.

A case of successful repeated lusutrombopag administration for thrombocytopenia in a patient with cirrhosis requiring multiple invasive procedures

M. Imamura, K. Chayama, H. Aikata, 2021, Kanzo.

Treatment outcomes after splenectomy with gastric devascularization or balloon-occluded retrograde transvenous obliteration for gastric varices: a propensity score-weighted analysis from a single institution

K. Awai, K. Chayama, H. Ohdan, 2020, Journal of Gastroenterology.

Comparison of the Clinical Outcome of Ramucirumab for Unresectable Hepatocellular Carcinoma with That of Prior Tyrosine Kinase Inhibitor Therapy

M. Imamura, K. Chayama, H. Kohno, 2021, Oncology.

Hepatic Arterial Infusion Chemotherapy Combined with Radiation Therapy for Advanced Hepatocellular Carcinoma with Tumor Thrombosis of the Main Trunk or Bilobar of the Portal Vein

K. Awai, M. Imamura, K. Chayama, 2021, Liver Cancer.

Combination therapies with NS5A, NS3 and NS5B inhibitors on different genotypes of hepatitis C virus in human hepatocyte chimeric mice

M. Imamura, N. Hiraga, K. Chayama, 2013, Gut.

Real-world efficacy of glecaprevir plus pibrentasvir for chronic hepatitis C patient with previous direct-acting antiviral therapy failures

M. Imamura, K. Chayama, D. Miki, 2018, Journal of Gastroenterology.

Effectiveness of Repeated Stereotactic Body Radiation Therapy for Hepatocellular Carcinoma—Consideration of the Locations of Target Lesions

M. Imamura, Y. Nagata, S. Oka, 2023, Cancers.

Correlation between Early Tumor Marker Response and Imaging Response in Patients with Advanced Hepatocellular Carcinoma Treated with Lenvatinib

M. Imamura, K. Chayama, H. Aikata, 2019, Oncology.

Early experience of seven hepatocellular carcinoma cases treated with regorafenib

M. Imamura, K. Chayama, H. Aikata, 2018, Clinical case reports.

Clinical outcomes of sorafenib treatment failure for advanced hepatocellular carcinoma and candidates for regorafenib treatment in real‐world practice

M. Imamura, K. Chayama, H. Aikata, 2018, Hepatology research : the official journal of the Japan Society of Hepatology.

Circulating cytokines and angiogenic factors based signature associated with the relative dose intensity during treatment in patients with advanced hepatocellular carcinoma receiving lenvatinib

M. Imamura, K. Chayama, D. Miki, 2020, Therapeutic advances in medical oncology.

Analysis of Survival and Response to Lenvatinib in Unresectable Hepatocellular Carcinoma

M. Imamura, H. Kohno, H. Aikata, 2022, Cancers.

Reply from the authors

M. Imamura, K. Chayama, H. Aikata, 2012, Hepatology Research.

Hepatic arterial infusion chemotherapy using 5‐fluorouracil and systemic interferon‐α for advanced hepatocellular carcinoma in combination with or without three‐dimensional conformal radiotherapy to venous tumor thrombosis in hepatic vein or inferior vena cava

K. Awai, K. Chayama, T. Kimura, 2012, Hepatology research : the official journal of the Japan Society of Hepatology.

Novel drug resistance-associated substitutions against pibrentasvir emerged in genotype 1b hepatitis C virus-infected human hepatocyte transplanted mice.

M. Imamura, K. Chayama, M. Hijikata, 2021, Biochemical and biophysical research communications.

Efficacy of glecaprevir and pibrentasvir treatment for genotype 1b hepatitis C virus drug resistance-associated variants in humanized mice.

M. Imamura, K. Chayama, M. Hijikata, 2019, The Journal of general virology.

Ultradeep Sequencing Study of Chronic Hepatitis C Virus Genotype 1 Infection in Patients Treated with Daclatasvir, Peginterferon, and Ribavirin

M. Imamura, N. Hiraga, K. Chayama, 2014, Antimicrobial Agents and Chemotherapy.

Impact of viral eradication by direct‐acting antivirals on the risk of hepatocellular carcinoma development, prognosis, and portal hypertension in hepatitis C virus‐related compensated cirrhosis patients

M. Imamura, K. Chayama, D. Miki, 2020, Hepatology research : the official journal of the Japan Society of Hepatology.

Comparison of hepatic arterial infusion chemotherapy between 5‐fluorouracil‐based continuous infusion chemotherapy and low‐dose cisplatin monotherapy for advanced hepatocellular carcinoma

K. Awai, M. Imamura, K. Chayama, 2018, Hepatology research : the official journal of the Japan Society of Hepatology.

Comparison of Outcome of Hepatic Arterial Infusion Chemotherapy Combined with Radiotherapy and Sorafenib for Advanced Hepatocellular Carcinoma Patients with Major Portal Vein Tumor Thrombosis

M. Imamura, K. Chayama, T. Kimura, 2018, Oncology.

Utility of controlled attenuation parameter measurement for assessing liver steatosis in Japanese patients with chronic liver diseases

M. Imamura, N. Hiraga, K. Chayama, 2013, Hepatology research : the official journal of the Japan Society of Hepatology.

Advanced liver fibrosis effects on the response to sofosbuvir‐based antiviral therapies for chronic hepatitis C

M. Imamura, K. Chayama, D. Miki, 2018, Journal of medical virology.

Real‐world efficacy of sofosbuvir plus velpatasvir therapy for patients with hepatitis C virus‐related decompensated cirrhosis

M. Imamura, K. Chayama, D. Miki, 2020, Hepatology research : the official journal of the Japan Society of Hepatology.

Management of refractory ascites attenuates muscle mass reduction and improves survival in patients with decompensated cirrhosis

M. Imamura, K. Chayama, H. Aikata, 2019, Journal of Gastroenterology.

Skeletal Muscle Loss during Tyrosine Kinase Inhibitor Treatment for Advanced Hepatocellular Carcinoma Patients

M. Imamura, K. Chayama, H. Aikata, 2019, Liver Cancer.

Comparison of clinical outcome of hepatic arterial infusion chemotherapy and sorafenib for advanced hepatocellular carcinoma according to macrovascular invasion and transcatheter arterial chemoembolization refractory status

M. Imamura, K. Chayama, H. Kohno, 2018, Journal of gastroenterology and hepatology.

Interferon lambda 4 polymorphism affects on outcome of telaprevir, pegylated interferon and ribavirin combination therapy for chronic hepatitis C

M. Imamura, K. Chayama, H. Aikata, 2014, Hepatology research : the official journal of the Japan Society of Hepatology.

Molecular signature predictive of long-term liver fibrosis progression to inform anti-fibrotic drug development

G. Klintmalm, S. Friedman, J. Marrero, 2021, Gastroenterology.

Complete response to pembrolizumab in advanced hepatocellular carcinoma with microsatellite instability

M. Imamura, K. Chayama, H. Aikata, 2020, Clinical Journal of Gastroenterology.

Successful retreatment with 12 weeks of glecaprevir and pibrentasvir for a genotype 2a HCV-infected hemodialysis patient who failed to respond to 8 weeks of prior glecaprevir and pibrentasvir therapy

M. Imamura, K. Chayama, H. Aikata, 2019, Clinical Journal of Gastroenterology.

Hepatic venous pressure gradient after balloon-occluded retrograde transvenous obliteration and liver stiffness measurement predict the prognosis of patients with gastric varices

K. Awai, M. Imamura, S. Oka, 2022, BMC gastroenterology.

Human microRNA hsa‐miR‐1231 suppresses hepatitis B virus replication by targeting core mRNA

N. Hiraga, D. Miki, T. Kohno, 2014, Journal of viral hepatitis.

Clinical outcomes of stereotactic body radiotherapy for elderly patients with hepatocellular carcinoma

M. Imamura, K. Chayama, T. Kimura, 2018, Hepatology research : the official journal of the Japan Society of Hepatology.

Pruritus in patients with chronic liver disease and serum autotaxin levels in patients with primary biliary cholangitis

M. Imamura, K. Chayama, Mio Tanaka, 2019, BMC Gastroenterology.

A case of acute liver failure with echovirus infection diagnosed by a multi-virus real-time PCR system

M. Imamura, K. Chayama, T. Wakita, 2021, IDCases.

Serum PreS1 and HBsAg ratio reflects liver fibrosis and predicts the development of hepatocellular carcinoma in chronic hepatitis B patients

M. Imamura, K. Chayama, D. Miki, 2021, Journal of viral hepatitis.

Acute liver injury in a non-alcoholic fatty liver disease patient with chloroform exposure: a case report

M. Imamura, K. Arihiro, S. Oka, 2023, Clinical Journal of Gastroenterology.

[Significant regression of a cavernous hepatic hemangioma to a sclerosed hemangioma over 12 years: a case study].

M. Imamura, K. Chayama, K. Arihiro, 2011, Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology.

Tumor Fibroblast Growth Factor Receptor 4 Level Predicts the Efficacy of Lenvatinib in Patients With Advanced Hepatocellular Carcinoma

M. Imamura, K. Chayama, H. Nakagawa, 2020, Clinical and translational gastroenterology.

Comparison of Outcome of Hepatic Arterial Infusion Chemotherapy and Sorafenib in Patients with Hepatocellular Carcinoma Refractory to Transcatheter Arterial Chemoembolization.

M. Imamura, K. Chayama, H. Kohno, 2016, Anticancer research.

In vitro analysis of hepatic stellate cell activation influenced by transmembrane 6 superfamily 2 polymorphism

M. Imamura, K. Chayama, D. Miki, 2020, Molecular medicine reports.

Blood immune cells from people with HIV on antiviral regimens that contain tenofovir alafenamide (TAF) and tenofovir disoproxil fumarate (TDF) have differential metabolic signatures.

A. Petcherski, O. Shirihai, T. Kelesidis, 2023, Metabolism: clinical and experimental.

Hepatic arterial infusion chemotherapy followed by sorafenib in patients with advanced hepatocellular carcinoma (HICS 55): an open label, non-comparative, phase II trial

K. Awai, M. Imamura, K. Chayama, 2018, BMC Cancer.

Preoperative PET-CT is useful for predicting recurrent extrahepatic metastasis of hepatocellular carcinoma after resection.

K. Awai, M. Imamura, K. Chayama, 2020, European journal of radiology.

Organic Anion-Transporting Polypeptide Genes Are Not Induced by the Pregnane X Receptor Activator Rifampin: Studies in Hepatocytes In Vitro and in Monkeys In Vivo

R. Subramanian, Y. Lai, E. Murakami, 2019, Drug Metabolism and Disposition.

Hepatic arterial infusion chemotherapy followed by sorafenib in patients with advanced hepatocellular carcinoma (HICS 55): an open label, non-comparative, phase II trial

K. Awai, M. Imamura, K. Chayama, 2018, BMC Cancer.

Serum interleukin-6 level predicts the prognosis for patients with alcohol-related acute-on-chronic liver failure

M. Imamura, H. Ohdan, S. Oka, 2023, Hepatology International.

Liver fibrosis assessments using FibroScan, virtual-touch tissue quantification, the FIB-4 index, and mac-2 binding protein glycosylation isomer levels compared with pathological findings of liver resection specimens in patients with hepatitis C infection

M. Imamura, K. Chayama, M. Yokozaki, 2020, BMC Gastroenterology.

Liver brosis assessments using FibroScan, Virtual-Touch tissue quanti cation, the FIB-4 index, and Mac-2 binding protein glycosylation isomer levels compared with pathological ndings of liver resection specimens in patients with hepatitis C infection

K. Chayama, M. Yokozaki, A. Hiramatsu, 2020 .

Impact and usefulness of the transition to the new MAFLD classification for non-B, non-C HCC: a retrospective cohort study

M. Imamura, S. Oka, H. Aikata, 2023, BMC Gastroenterology.

Evaluation of Response to Atezolizumab Plus Bevacizumab in Patients with Advanced Hepatocellular Carcinoma Using the Combination of Response Evaluation Criteria in Solid Tumors and Alpha-Fetoprotein

M. Imamura, S. Oka, D. Miki, 2023, Cancers.

Correlation between serum pro‐inflammatory cytokine levels and the prognosis of the patients with acute liver failure

M. Imamura, H. Ohdan, S. Oka, 2023, Journal of gastroenterology and hepatology.

Usefulness of combining gadolinium-ethoxybenzyl-diethylenetriamine pentaacetic acid-enhanced magnetic resonance imaging and contrast-enhanced ultrasound for diagnosing the macroscopic classification of small hepatocellular carcinoma

M. Imamura, K. Chayama, H. Aikata, 2015, European Radiology.

Differences in characteristics of glucose intolerance between patients with NAFLD and chronic hepatitis C as determined by CGMS

T. Saibara, K. Chayama, T. Kawaguchi, 2017, Scientific Reports.

HBV upregulates TRAIL-R3 expression in hepatocytes for escaping both cell apoptosis and suppression of their replication by TRAIL.

M. Imamura, K. Chayama, T. Fujita, 2022, Journal of Infectious Diseases.

Successful Lenvatinib Re-challenge following Atezolizumab Plus Bevacizumab Combination Therapy Failure for Unresectable Hepatocellular Carcinoma

M. Imamura, H. Aikata, E. Murakami, 2022, Internal medicine.

Percutaneous transvenous shunt occlusion for portosystemic encephalopathy due to lenvatinib administration to a patient with hepatocellular carcinoma and portosystemic shunt

K. Awai, M. Imamura, K. Chayama, 2019, Clinical journal of gastroenterology.

Association of Hepatobiliary Phase of Gadoxetic-Acid-Enhanced MRI Imaging with Immune Microenvironment and Response to Atezolizumab Plus Bevacizumab Treatment

K. Awai, M. Imamura, K. Chayama, 2023, Cancers.

Risk Factors for Early Onset of Proteinuria in Patients Receiving Atezolizumab Plus Bevacizumab for Unresectable Hepatocellular Carcinoma

M. Imamura, H. Aikata, E. Murakami, 2022, Liver Cancer.

The Analysis of Muscle Volume Measured by Bioelectrical Impedance in Patients with Hepatocellular Carcinoma Treated with First-Line Atezolizumab plus Bevacizumab Combination Therapy or First-Line Lenvatinib

M. Imamura, S. Oka, D. Miki, 2023, Oncology.

Sodium-glucose cotransporter-2 inhibitors improve FibroScan-aspartate aminotransferase scores in patients with nonalcoholic fatty liver disease complicated by type 2 diabetes

M. Imamura, S. Oka, D. Miki, 2023, European journal of gastroenterology & hepatology.

Comparison of Outcome of Hepatic Arterial Infusion Chemotherapy Combined with Radiotherapy and Sorafenib for Advanced Hepatocellular Carcinoma Patients with Major Portal Vein Tumor Thrombosis

M. Imamura, K. Chayama, T. Kimura, 2018, Oncology.

Human microRNA hsa‐miR‐1231 suppresses hepatitis B virus replication by targeting core mRNA

M. Imamura, N. Hiraga, K. Chayama, 2014, Journal of viral hepatitis.

Structure of Hepatitis C Virus Polymerase in Complex with Primer-Template RNA

M. Otto, A. Lam, M. Sofia, 2012, Journal of Virology.

Lenvatinib activates anti-tumor immunity by suppressing immunoinhibitory infiltrates in the tumor microenvironment of advanced hepatocellular carcinoma

M. Imamura, K. Chayama, D. Miki, 2023, Communications medicine.

Efficacy and safety of atezolizumab plus bevacizumab in patients with portal hypertension for unresectable hepatocellular carcinoma

D. Miki, E. Murakami, T. Kawaoka, 2024, Cancer medicine.

Therapeutic Efficacy and Safety of Lenvatinib after Atezolizumab Plus Bevacizumab for Unresectable Hepatocellular Carcinoma

D. Miki, S. Takaki, N. Mori, 2023, Cancers.

Deep learning and digital pathology powers prediction of HCC development in steatotic liver disease.

K. Chayama, M. Taniai, Yuya Seko, 2024, Hepatology.

Integrator complex subunit 6 promotes hepatocellular steatosis via β-catenin-PPARγ axis

Y. Otani, E. Murakami, Keishi Kanno, 2024, Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids.

A case of complete response to radiotherapy combined with durvalumab and tremelimumab in a patient with unknown primary hepatocellular carcinoma arising in the lumbar spine.

D. Miki, E. Murakami, T. Kawaoka, 2024, Clinical journal of gastroenterology.