M. Lauber

发表

Tuning selectivity in cation-exchange chromatography applied for monoclonal antibody separations, part 2: Evaluation of recent stationary phases.

D. Guillarme, A. Beck, S. Fekete, 2019, Journal of pharmaceutical and biomedical analysis.

Enhanced Detection of Low-Abundance Host Cell Protein Impurities in High-Purity Monoclonal Antibodies Down to 1 ppm Using Ion Mobility Mass Spectrometry Coupled with Multidimensional Liquid Chromatography.

Weibin Chen, A. Chakraborty, M. Lauber, 2015, Analytical chemistry.

Mapping IgG Subunit Glycoforms Using HILIC and a Wide-Pore Amide Stationary Phase

M. Lauber, Stephan M. Koza, S. Koza, 2015 .

Unique Fragmentation of Singly Charged DEST Cross-Linked Peptides

J. Reilly, Yi He, M. Lauber, 2012, Journal of The American Society for Mass Spectrometry.

Empirical correction of non-linear pH gradients and a tool for application to protein ion exchange chromatography.

D. Guillarme, S. Fekete, Amarande Murisier, 2021, Journal of chromatography. A.

Coupling non-denaturing chromatography to mass spectrometry for the characterization of monoclonal antibodies and related products.

J. Veuthey, D. Guillarme, A. Beck, 2020, Journal of pharmaceutical and biomedical analysis.

Impact of the column on effluent pH in cation exchange pH gradient chromatography, a practical study.

D. Guillarme, A. Beck, S. Fekete, 2020, Journal of chromatography. A.

Optimizing LC-MS Separations of mAbs using a BioResolve SCX mAb Column and IonHance CX- MS pH Concentrates Optimizing LC-MS Separations of mAbs using a BioResolve SCX mAb Column and IonHance CX-MS pH Concentrates

M. Lauber, Andrew Schmudlach, Samantha Ippoliti, 2020 .

Aptamer-based immunoaffinity LC-MS using an ultra-short column for rapid attomole level quantitation of intact mAbs.

D. Guillarme, S. Fekete, Amarande Murisier, 2021, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

Orthogonal Middle-up Approaches for Characterization of the Glycan Heterogeneity of Etanercept by Hydrophilic Interaction Chromatography Coupled to High-Resolution Mass Spectrometry.

D. Guillarme, D. Stoll, V. D’Atri, 2018, Analytical chemistry.

The impact of low adsorption surfaces for the analysis of DNA and RNA oligonucleotides.

D. Guillarme, V. D’Atri, Kelly Zhang, 2022, Journal of chromatography. A.

Size Exclusion and Ion Exchange Chromatographic Hardware Modified with a Hydrophilic Hybrid Surface.

S. Fekete, M. DeLano, K. Wyndham, 2022, Analytical chemistry.

Investigating the secondary interactions of packing materials for size-exclusion chromatography of therapeutic proteins.

S. Fekete, N. Lawrence, M. Lauber, 2022, Journal of chromatography. A.

Hydrophilic Interaction Chromatography Hyphenated with Mass Spectrometry: A Powerful Analytical Tool for the Comparison of Originator and Biosimilar Therapeutic Monoclonal Antibodies at the Middle-up Level of Analysis.

D. Guillarme, V. D’Atri, A. Beck, 2017, Analytical chemistry.

HILIC Glycopeptide Mapping with a Wide-Pore Amide Stationary Phase

M. Lauber, S. Koza, 2016 .

Assessing the impact of nonspecific binding on oligonucleotide bioanalysis.

B. Koshel, M. Gilar, M. Lauber, 2021, Bioanalysis.

Low Adsorption UPLC Systems and Columns Based on MaxPeak High Performance Surfaces: The ACQUITY Premier Solution

P. Rainville, M. DeLano, C. Boissel, 2021 .

Developing High Resolution HILIC Separations of Intact Glycosylated Proteins Using a Wide-Pore Amide-Bonded Stationary Phase

M. Lauber, P. Iraneta, B. A. Alden, 2015 .

RAPID PREPARATION OF RELEASED N-GLYCANS FOR HILIC ANALYSIS USING A NOVEL FLUORESCENCE AND MS-ACTIVE LABELING REAGENT

D. Brousmiche, C. Taron, K. Fountain, 2015 .

Ultra-short ion-exchange columns for fast charge variants analysis of therapeutic proteins.

D. Guillarme, A. Beck, S. Fekete, 2021, Journal of chromatography. A.

Characterizing various monoclonal antibodies with milder reversed phase chromatography conditions.

D. Guillarme, Balázs Bobály, V. D’Atri, 2018, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

Characterization of an antibody-drug conjugate by hydrophilic interaction chromatography coupled to mass spectrometry.

D. Guillarme, D. Stoll, V. D’Atri, 2018, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

Practical considerations on the particle size and permeability of ion-exchange columns applied to biopharmaceutical separations.

D. Guillarme, S. Fekete, Amarande Murisier, 2019, Journal of chromatography. A.

Online IEX-MS of mAb Charge Variants Using a BioResolve SCX mAb Column, IonHance CX-MS pH Concentrates, and BioAccord System : Waters

M. Lauber, Andrew Schmudlach, Samantha Ippoliti, 2019 .

High sensitivity LC-MS profiling of antibody-drug conjugates with difluoroacetic acid ion pairing

C. Legido-Quigley, M. Lauber, J. Nguyen, 2019, mAbs.

Robustness and repeatability of GlycoWorks RapiFluor-MS IgG N-glycan profiling in a long-term high-throughput glycomic study.

Alicia M Bielik, G. Lauc, C. Taron, 2021, Glycobiology.

Microflow size exclusion chromatography to preserve micromolar affinity complexes and achieve subunit separations for native state mass spectrometry.

M. Lauber, H. Shion, X. Liu, 2022, Journal of chromatography. A.

Capillary liquid chromatography coupled with mass spectrometry for analysis of nanogram protein quantities on a wide-pore superficially porous particle column in top-down proteomics.

J. Camadro, M. Lauber, G. Chevreux, 2022, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

Purification and properties of DNA polymerases from chick embryo.

G. Brun, F. Rougeon, M. Lauber, 1974, European journal of biochemistry.

In vitro and in vivo chemical labeling of ribosomal proteins: a quantitative comparison.

J. Reilly, Ethan G. Jaffee, M. Lauber, 2012, Analytical chemistry.

Dynamics of Ribosomal Protein S1 on a Bacterial Ribosome with Cross-Linking and Mass Spectrometry

Juri Rappsilber, James P. Reilly, J. Rappsilber, 2012, Molecular & Cellular Proteomics.

Structural analysis of a prokaryotic ribosome using a novel amidinating cross-linker and mass spectrometry.

J. Reilly, M. Lauber, 2011, Journal of proteome research.

Reducing metal-ion mediated adsorption of acidic peptides in RPLC-based assays using hybrid silica chromatographic surfaces.

Weibin Chen, Y. Yu, R. Birdsall, 2021, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

Negative gradient slope methods to improve the separation of closely eluting proteins.

D. Guillarme, S. Fekete, Amarande Murisier, 2020, Journal of chromatography. A.

B. subtilis ribosomal proteins: structural homology and post-translational modifications.

J. Reilly, M. Lauber, W. Running, 2009, Journal of proteome research.

Rapid Preparation of Released N-Glycans for HILIC Analysis Using a Labeling Reagent that Facilitates Sensitive Fluorescence and ESI-MS Detection.

Y. Yu, D. Brousmiche, C. Taron, 2015, Analytical chemistry.

Comprehensive Characterization of the N and O-Linked Glycosylation of a Recombinant Human EPO

Waters, Erin E. Chambers, M. Lauber, 2016 .

Characterization of EPO N-Glycans using RapiFluor-MS and HILIC Profiling : Waters

Erin E. Chambers, R. Bharadwaj, M. Lauber, 2015 .

Using Hybrid Organic-Inorganic Surface Technology to Mitigate Analyte Interactions with Metal Surfaces in UHPLC.

M. Gilar, T. H. Walter, C. Boissel, 2021, Analytical chemistry.

Development of optimized drug-like small molecule inhibitors of the SARS-CoV-2 3CL protease for treatment of COVID-19

Seo Jung Hong, B. Stockwell, P. Rajbhandari, 2022, Nature Communications.

Improved Identification and Quantification of Host Cell Proteins (HCPs) in Biotherapeutics Using Liquid Chromatography-Mass Spectrometry

Weibin Chen, K. Fountain, M. Stapels, 2015 .

Assay for Identification and Quantification of Host Cell Protein Impurities in High-Purity Monoclonal Antibodies Down to 1 ppm: An Inter-Laboratory Study : Waters

Weibin Chen, M. Lauber, B. Williams, 2015 .

Utility of a high coverage phenyl-bonding and wide-pore superficially porous particle for the analysis of monoclonal antibodies and related products.

D. Guillarme, Balázs Bobály, A. Beck, 2018, Journal of chromatography. A.

Challenges and emerging trends in liquid chromatography-based analyses of mRNA pharmaceuticals

G. Isaac, S. Fekete, R. Birdsall, 2022, Journal of pharmaceutical and biomedical analysis.

Ultra-Fast Middle-Up Reversed Phase Liquid Chromatography Analysis of Complex Bispecific Antibodies Obtained in Less Than One Minute

D. Guillarme, Vincent Larraillet, V. D’Atri, 2022, Pharmaceutics.

Use of Ultra-short Columns for Therapeutic Protein Separations, Part 2: Designing the Optimal Column Dimension for Reversed-Phase Liquid Chromatography.

J. Veuthey, D. Guillarme, A. Beck, 2020, Analytical chemistry.

Influence of water-extractable organic matter from Opalinus Clay on the sorption and speciation of Ni(II), Eu(III) and Th(IV)

B. Baeyens, M. Lauber, M. Glaus, 2005 .

Theoretical Study on Solute Migration and Band Broadening Occurring in Pressure-Enhanced Liquid Chromatography

S. Fekete, M. Lauber, 2023, Journal of Chromatography A.

High-resolution peptide mapping separations with MS-friendly mobile phases and charge-surface-modified C18.

K. Fountain, M. Lauber, P. Iraneta, 2013, Analytical chemistry.

Potential of hydrophilic interaction chromatography for the analytical characterization of protein biopharmaceuticals.

J. Veuthey, A. Periat, D. Guillarme, 2016, Journal of chromatography. A.

Optimizing test approaches for the detection of exposed metal surfaces within a chromatographic flow path.

M. Lauber, E. Hoyes, J. Simeone, 2022, Journal of chromatography. A.

Chromatographic strategies for the analytical characterization of adeno-associated virus vector-based gene therapy products

D. Guillarme, Raphael Ruppert, V. D’Atri, 2023, TrAC Trends in Analytical Chemistry.

Direct coupling of size exclusion chromatography and mass spectrometry for the characterization of complex monoclonal antibody products

D. Guillarme, V. D’Atri, S. Fekete, 2022, Journal of separation science.

Use of Ultrashort Columns for Therapeutic Protein Separations. Part 1: Theoretical Considerations and Proof of Concept.

J. Veuthey, D. Guillarme, Balázs Bobály, 2020, Analytical chemistry.

Expediting the chromatographic analysis of COVID-19 antibody therapeutics with ultra-short columns, retention modeling and automated method development

D. Guillarme, S. Fekete, M. Lauber, 2022, Journal of Pharmaceutical and Biomedical Analysis.

A generic method for intact and subunit level characterization of mAb charge variants by native mass spectrometry.

M. Lauber, N. Bihoreau, G. Chevreux, 2019, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

Charge-Variant Analysis of Antibody-Drug Conjugates with Cation-Exchange Chromatography

M. Lauber, Hua Yang, Qi Wang, 2019 .

Quantitative N-Glycan Profiling of Therapeutic Monoclonal Antibodies Performed by Middle-Up Level HILIC-HRMS Analysis

D. Guillarme, K. Sandra, V. D’Atri, 2021, Pharmaceutics.

Pressure-Enhanced Liquid Chromatography, a Proof of Concept: Tuning Selectivity with Pressure Changes and Gradients

S. Fekete, M. Lauber, Michael O. Fogwill, 2022, Analytical chemistry.

High sensitivity acidic N-glycan profiling with MS-enhancing derivatization and mixed mode chromatography.

M. Lauber, Xiaoxiao Liu, Qi Wang, 2022, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

Towards a simple on-line coupling of ion exchange chromatography and native mass spectrometry for the detailed characterization of monoclonal antibodies.

D. Guillarme, J. Bourquin, V. D’Atri, 2021, Journal of chromatography. A.

Ratiometric pulse-chase amidination mass spectrometry as a probe of biomolecular complex formation.

D. Giedroc, J. Reilly, M. Lauber, 2011, Analytical chemistry.

Designing a New Particle Technology for Reversed-Phase Separations of Proteins

M. Lauber, D. Walsh, G. Izzo, 2018 .

Separation of Plasmid DNA Topological Forms, Messenger RNA, and Lipid Nanoparticle Aggregates Using an Ultrawide Pore Size Exclusion Chromatography Column

S. Fekete, Kelly Zhang, M. Lauber, 2023, Analytical chemistry.

Size exclusion chromatography of biopharmaceutical products: From current practices for proteins to emerging trends for viral vectors, nucleic acids and lipid nanoparticles.

D. Guillarme, V. D’Atri, S. Fekete, 2024, Journal of chromatography. A.

Considering the selectivity of pore size gradient size exclusion chromatography columns.

S. Fekete, M. Lauber, Mingcheng Xu, 2024, Journal of chromatography. A.

Fast and efficient size exclusion chromatography of adeno associated viral vectors with 2.5 micrometer particle low adsorption columns.

S. Fekete, M. Lauber, Lavelay Kizekai, 2023, Journal of chromatography. A.

Insights on further improving fast size exclusion chromatography separations of biopharmaceuticals using 2.1 millimetre column diameters.

S. Fekete, M. Lauber, 2023, Journal of chromatography. A.