J. Dotor

发表

P144, a Transforming Growth Factor beta inhibitor peptide, generates antitumoral effects and modifies SMAD7 and SKI levels in human glioblastoma cell lines.

B. Meléndez, J. Rey, P. Hau, 2016, Cancer letters.

In Vitro and In Vivo Down-Regulation of Regulatory T Cell Activity with a Peptide Inhibitor of TGF-β11

J. Prieto, S. V. van Deventer, J. Lasarte, 2008, The Journal of Immunology.

Induction of monocyte chemoattractant protein-1 and interleukin-10 by TGFbeta1 in melanoma enhances tumor infiltration and immunosuppression.

J. Riezu-Boj, P. Sarobe, Fernando Aranda, 2011, Cancer research.

Topical application of a peptide inhibitor of transforming growth factor-beta1 ameliorates bleomycin-induced skin fibrosis.

Jesús Prieto, Javier Dotor, J. Prieto, 2005, The Journal of investigative dermatology.

Blocking TGF-β1 protects the peritoneal membrane from dialysate-induced damage.

R. Selgas, F. Rodríguez-Pascual, A. Aguilera, 2011, Journal of the American Society of Nephrology : JASN.

Inhibitor of TGF-Regulatory T Cell Activity with a Peptide In Vitro and In Vivo Down-Regulation of Borrás

J. Prieto, S. V. Deventer, J. Lasarte, 2008 .

Soluble factors derived from tumor mammary cell lines induce a stromal mammary adipose reversion in human and mice adipose cells. Possible role of TGF-β1 and TNF-α

J. Guerrero, J. Dotor, N. Tobar, 2009, Breast Cancer Research and Treatment.

TGFbeta1 antagonistic peptides inhibit TGFbeta1-dependent angiogenesis.

A. Albini, A. Cantelmo, S. Serratì, 2009, Biochemical pharmacology.

Co-migration of colon cancer cells and CAFs induced by TGFβ1 enhances liver metastasis

M. Redrado, A. Calvo, I. Manrique, 2015, Cell and Tissue Research.

Carcinoma‐associated fibroblasts derive from mesothelial cells via mesothelial‐to‐mesenchymal transition in peritoneal metastasis

K. Stamatakis, J. Jimenez-Heffernan, C. Cabañas, 2013, The Journal of pathology.

In vitro cell response on CP-Ti surfaces functionalized with TGF-β1 inhibitory peptides

C. Aparicio, P. Galindo-Moreno, F. Gil, 2018, Journal of Materials Science: Materials in Medicine.

Enhancing immunogenicity of a CTL epitope from carcinoembryonic antigen by selective amino acid replacements.

J. Prieto, E. Huarte, J. Lasarte, 2002, Clinical cancer research : an official journal of the American Association for Cancer Research.

Role of TGF‐β and PGE2 in T cell responses during Plasmodium yoelii infection

Ana Rodriguez, J. Dotor, F. Borrás-Cuesta, 2007 .

In Vitro and In Vivo Down-Regulation of Regulatory T Cell Activity with a Peptide Inhibitor of TGF- 1

J. Lasarte, J. Riezu-Boj, P. Sarobe, 2008 .

Identification of peptide inhibitors of transforming growth factor beta 1 using a phage-displayed peptide library.

J. Prieto, J. Lasarte, J. Riezu-Boj, 2007, Cytokine.

Combined targeting of TGF-β1 and integrin β3 impairs lymph node metastasis in a mouse model of non-small-cell lung cancer

P. Altevogt, R. Peláez, Xabier Morales, 2014, Molecular Cancer.

A role for endoglin as a suppressor of malignancy during mouse skin carcinogenesis.

J. Fernández-Piqueras, Javier Santos, M. Quintanilla, 2007, Cancer research.

S-adenosylmethionine regulates cytoplasmic HuR via AMP-activated kinase.

Shelly C. Lu, M. Vázquez‐Chantada, L. A. Martínez-Cruz, 2006, Gastroenterology.

Density and duration of pneumococcal carriage is maintained by transforming growth factor β1 and T regulatory cells.

W. Coward, A. Kadioglu, S. Gordon, 2014, American journal of respiratory and critical care medicine.

Surface immobilization and bioactivity of TGF-β1 inhibitor peptides for bone implant applications.

D. Rodriguez, C. Aparicio, F. Gil, 2016, Journal of biomedical materials research. Part B, Applied biomaterials.

A pathogenetic role for endothelin-1 in peritoneal dialysis-associated fibrosis.

F. Rodríguez-Pascual, M. J. López-Armada, J. Dotor, 2015, Journal of the American Society of Nephrology : JASN.

Modulation of regulatory T‐cell activity in combination with interleukin‐12 increases hepatic tolerogenicity in woodchucks with chronic hepatitis B

J. Prieto, G. González-Aseguinolaza, Á. Vales, 2012, Hepatology.

Novel pharmacologic strategies to protect the liver from ischemia-reperfusion injury.

J. Prieto, M. Ávila, C. Berasain, 2008, Recent patents on cardiovascular drug discovery.

Mesothelial‐to‐mesenchymal transition in the pathogenesis of post‐surgical peritoneal adhesions

J. Jimenez-Heffernan, Paloma Martin, M. Coronado, 2016, The Journal of pathology.

Transforming growth factor beta (TGF-β) activity in immuno-oncology studies.

Marianna Di Scala, Fernando Aranda, G. Gallo-Oller, 2020, Methods in enzymology.

Effect of P144® (Anti-TGF-β) in an “In Vivo” Human Hypertrophic Scar Model in Nude Mice

B. Hontanilla, S. Qiu, J. Dotor, 2015, PloS one.

A new background subtraction method for Western blot densitometry band quantification through image analysis software.

Raquel Ordoñez, Gabriel Gallo-Oller, Javier Dotor, 2018, Journal of immunological methods.

GDF5 Regulates TGFß-Dependent Angiogenesis in Breast Carcinoma MCF-7 Cells: In Vitro and In Vivo Control by Anti-TGFß Peptides

Javier Dotor, Eugenio Torre, L. Magnelli, 2012, PloS one.

Induction of potent and long-lasting CD4 and CD8 T-cell responses against hepatitis C virus by immunization with viral antigens plus poly(I:C) and anti-CD40.

J. Prieto, J. Lasarte, J. Esteban, 2007, Antiviral research.

Combined immunization with adjuvant molecules poly(I:C) and anti-CD40 plus a tumor antigen has potent prophylactic and therapeutic antitumor effects

J. Prieto, J. Lasarte, A. Zabaleta, 2007, Cancer Immunology, Immunotherapy.

A novel lung cancer signature mediates metastatic bone colonization by a dual mechanism.

Javier De Las Rivas, Javier Dotor, Diego Luis-Ravelo, 2008, Cancer research.

Co-migration of colon cancer cells and CAFs induced by TGFβ1 enhances liver metastasis

M. Redrado, A. Calvo, I. Manrique, 2015, Cell and Tissue Research.

P144 a Transforming Growth Factor Beta Inhibitor Peptide, Generates Antifibrogenic Effects in a Radiotherapy Induced Fibrosis Model

M. San-Julián, J. Dotor, S. Cruz-Morande, 2022, Current oncology.

Improved Chondrogenic Capacity of Collagen Hydrogel-Expanded Chondrocytes: In Vitro and in Vivo Analyses.

Javier Dotor, J. Dotor, Julio Duart, 2014, The Journal of bone and joint surgery. American volume.

Peptide inhibitors of transforming growth factor‐β enhance the efficacy of antitumor immunotherapy

J. Prieto, P. Berraondo, J. Lasarte, 2009, International journal of cancer.

Blockade of TGF-β 1 Signalling Inhibits Cardiac NADPH Oxidase Overactivity in Hypertensive Rats

Arantxa González, J. Díez, G. Zalba, 2012, Oxidative medicine and cellular longevity.

A synthetic peptide from transforming growth factor beta type III receptor inhibits liver fibrogenesis in rats with carbon tetrachloride liver injury.

J. Prieto, P. Greenwel, I. Castilla-Cortázar, 2003, Cytokine.

Therapeutic effect of a peptide inhibitor of TGF-β on pulmonary fibrosis.

J. Lasarte, J. Riezu-Boj, P. Sarobe, 2011, Cytokine.

Topical Application of TGF-β1 Peptide Inhibitors for the Therapy of Skin Fibrosis

J. Pablos, J. Dotor, 2008 .

Harnessing High Density Lipoproteins to Block Transforming Growth Factor Beta and to Inhibit the Growth of Liver Tumor Metastases

J. Prieto, P. Berraondo, V. Umansky, 2014, PloS one.

The role of Alk-1 and Alk-5 in the mechanosensing of chondrocytes

J. Dotor, P. Sanz-Ramos, Í. Izal-Azcárate, 2014, Cellular & Molecular Biology Letters.

CD4+/CD25+ Regulatory Cells Inhibit Activation of Tumor-Primed CD4+ T Cells with IFN-γ-Dependent Antiangiogenic Activity, as well as Long-Lasting Tumor Immunity Elicited by Peptide Vaccination 1

J. Prieto, I. Melero, J. Lasarte, 2003, The Journal of Immunology.

Effect of the Inhibitor Peptide of the Transforming Growth Factor β (p144®) in a New Silicone Pericapsular Fibrotic Model in Pigs

B. Hontanilla, J. Dotor, Andrea San-Martín, 2010, Aesthetic Plastic Surgery.

Transforming growth factor (TGF)‐β signalling is increased in rheumatoid synovium but TGF‐β blockade does not modify experimental arthritis

J. Pablos, G. Criado, B. Santiago, 2013, Clinical and experimental immunology.

Transforming Growth Factor-Beta Inhibition Reduces Progression of Early Choroidal Neovascularization Lesions in Rats: P17 and P144 Peptides

A. García-Layana, J. Zarranz-Ventura, Á. Salinas-Alamán, 2013, PloS one.

and in Vivo Analyses Improved Chondrogenic Capacity of Collagen Hydrogel-Expanded Chondrocytes: In Vitro

Joshua T. Morgan, P. Janmey, P. Russell, 2015 .

Quantitative method for in vitro matrigel invasiveness measurement through image analysis software

Gabriel Gallo-Oller, Juan A. Rey, Javier Dotor, 2014, Molecular Biology Reports.

A synthetic peptide from transforming growth factor-beta1 type III receptor prevents myocardial fibrosis in spontaneously hypertensive rats.

J. Lasarte, Arantxa González, P. Sarobe, 2008, Cardiovascular research.

Quantitative method for in vitro matrigel invasiveness measurement through image analysis software

J. Rey, J. Castresana, G. Gallo-Oller, 2014, Molecular Biology Reports.

Transforming growth factor-β inhibition decreases diode laser-induced choroidal neovascularization development in rats: P17 and P144 peptides.

A. García-Layana, J. Zarranz-Ventura, Á. Salinas-Alamán, 2011, Investigative ophthalmology & visual science.

Systemic sclerosis endothelial cells recruit and activate dermal fibroblasts by induction of a connective tissue growth factor (CCN2)/transforming growth factor β-dependent mesenchymal-to-mesenchymal transition.

E. Giannoni, L. Magnelli, S. Bombardieri, 2013, Arthritis and rheumatism.

Role of TGF-beta and PGE2 in T cell responses during Plasmodium yoelii infection.

J. Dotor, F. Borrás-Cuesta, C. Ocaña-Morgner, 2007, European Journal of Immunology.

A synthetic peptide from transforming growth factor-β₁ type III receptor inhibits NADPH oxidase and prevents oxidative stress in the kidney of spontaneously hypertensive rats.

Arantxa González, G. Zalba, B. Lopez, 2013, Antioxidants & redox signaling.

TGFbeta1 antagonistic peptides inhibit TGFbeta1-dependent angiogenesis.

A. Albini, A. Cantelmo, S. Serratì, 2009, Biochemical pharmacology.

A synthetic peptide from transforming growth factor beta type III receptor inhibits liver fibrogenesis in rats with carbon tetrachloride liver injury.

P. Greenwel, I. Castilla-Cortázar, J. Lasarte, 2003, Cytokine.

The role of Alk-1 and Alk-5 in the mechanosensing of chondrocytes

J. Dotor, P. Sanz-Ramos, Í. Izal-Azcárate, 2014, Cellular & Molecular Biology Letters.