Yan Y. Zhang

发表

Synthesis and biological evaluation of 4-(pyridin-4-oxy)-3-(3,3-difluorocyclobutyl)-pyrazole derivatives as novel potent transforming growth factor-β type 1 receptor inhibitors.

Xue Li, Liwen Zhao, Guofeng Xu, 2020, European journal of medicinal chemistry.

Design, synthesis, crystal structure, insecticidal activity, molecular docking, and QSAR studies of novel N3-substituted imidacloprid derivatives.

Dan Wu, Hai‐tao Yu, Yan Y. Zhang, 2014, Journal of agricultural and food chemistry.

An Efficient and Scalable Synthesis of (2R,αS)-3,4-Dihydro-2-[3-(1,1,2,2-tetrafluoroethoxy)phenyl]-5-[3-(trifluoromethoxy)-phenyl]-α-(trifluoromethyl)-1(2H)-quinolineethanol: A Potent CETP Inhibitor

Songfeng Lu, G. Kuo, W. Murray, 2010 .

A novel orally active microtubule destabilizing agent S-40 targets the colchicine-binding site and shows potent antitumor activity.

T. Du, Qinghua Wang, Xiaoguang Chen, 2020, Cancer letters.

Synthesis and biological characterization of L-N(6)-(1-iminoethyl)lysine 5-tetrazole-amide, a prodrug of a selective iNOS inhibitor.

M. Currie, W. M. Moore, G. Jerome, 2002, Journal of medicinal chemistry.

Conformationally restricted 1,5-diarylpyrazoles are selective COX-2 inhibitors

C. Koboldt, J. Talley, S. Bertenshaw, 1996 .

Discovery of a novel photoswitchable PI3K inhibitor toward optically-controlled anticancer activity.

T. Du, Yan Y. Zhang, M. Ji, 2022, Bioorganic & medicinal chemistry.

Synthesis and structure-activity relationships of pyrazine-pyridine biheteroaryls as novel, potent, and selective vascular endothelial growth factor receptor-2 inhibitors.

S. Emanuel, R. H. Gruninger, Angel R. Fuentes-Pesquera, 2005, Journal of medicinal chemistry.

1,2‐Diarylimidazoles as Potent, Cyclooxygenase‐2 Selective, and Orally Active Antiinflammatory Agents.

C. Koboldt, K. Seibert, P. Isakson, 2010 .

Synthesis, biological activities and structure-activity relationships for new avermectin analogues.

Jian Zhang, Hai‐tao Yu, Yan Y. Zhang, 2016, European journal of medicinal chemistry.

Synthesis and identification of [1,3,5]triazine-pyridine biheteroaryl as a novel series of potent cyclin-dependent kinase inhibitors.

Xin Chen, Yan Zhang, S. Emanuel, 2005, Journal of medicinal chemistry.

Synthesis, Biological Activities, and Quantitative Structure–Activity Relationship (QSAR) Study of Novel Camptothecin Analogues

Dan Wu, Wei Wei, Yan Y. Zhang, 2015, Molecules.

3,4-diarylpyrazoles: Potent and selective inhibitors of cyclooxygenase-2

C. Koboldt, K. Seibert, P. Isakson, 1997 .

Discovery of 4-Methyl Quinazoline Based PI3K Inhibitors for the Potential Treatment of Idiopathic Pulmonary Fibrosis.

T. Du, Xiaoguang Chen, Yan Li, 2019, Journal of Medicinal Chemistry.

Discovery of new thieno[2,3-d]pyrimidine and thiazolo[5,4-d]pyrimidine derivatives as orally active phosphoinositide 3-kinase inhibitors.

Xiaoguang Chen, Yan Li, L. Sheng, 2020, Bioorganic & medicinal chemistry.

Design, Synthesis, and Biological Evaluation of 4-Methyl Quinazoline Derivatives as Anticancer Agents Simultaneously Targeting Phosphoinositide 3-Kinases and Histone Deacetylases.

Xiaoguang Chen, Yan Li, L. Sheng, 2019, Journal of medicinal chemistry.

Synthesis and Biological Evaluation of 4-(pyridine-4-oxy)-3-(tetrahydro-2H-pyran-4-yl)-pyrazole Derivatives as Novel, Potent of ALK5 Receptor Inhibitors.

Yan Y. Zhang, Hai Wang, Zhuangzhuang Yu, 2022, Bioorganic & medicinal chemistry letters.

Identification of Novel Thiazolo[5,4-b]Pyridine Derivatives as Potent Phosphoinositide 3-Kinase Inhibitors

Yan Y. Zhang, Yi Dong, Kehui Zhang, 2020, Molecules.

SD0006: A Potent, Selective and Orally Available Inhibitor of p38 Kinase

R. Kurumbail, G. Anderson, J. Monahan, 2009, Pharmacology.

Chemical synthesis, microbial transformation and biological evaluation of tetrahydroprotoberberines as dopamine D1/D2 receptor ligands.

Laiyu Sun, Yan Y. Zhang, Chao Chen, 2019, Bioorganic & medicinal chemistry.

Evaluation of COX-1/COX-2 selectivity and potency of a new class of COX-2 inhibitors.

J. Gierse, K. Seibert, J. Masferrer, 2008, European journal of pharmacology.

Valdecoxib: Assessment of Cyclooxygenase-2 Potency and Selectivity

J. Gierse, C. Koboldt, K. Seibert, 2005, Journal of Pharmacology and Experimental Therapeutics.

Design, synthesis and biological evaluation of novel FXIa inhibitors with 2-phenyl-1H-imidazole-5-carboxamide moiety as P1 fragment.

Yan-hua Mou, Jun Gao, Yan Y. Zhang, 2021, European journal of medicinal chemistry.

Discovery and Biological Evaluation of a Series of Pyrrolo[2,3-b]pyrazines as Novel FGFR Inhibitors

Tongchao Liu, B. Xiong, Hongchun Liu, 2017, Molecules.

Synthesis and identification of [1,2,4]thiadiazole derivatives as a new series of potent and orally active dual agonists of peroxisome proliferator-activated receptors alpha and delta.

A. Gibbs, M. Reuman, R. Russell, 2007, Journal of medicinal chemistry.

Design, Synthesis, and Biological Evaluation of a Novel Photocaged PI3K Inhibitor toward Precise Cancer Treatment.

Xiaoguang Chen, Yan Y. Zhang, M. Ji, 2021, Journal of medicinal chemistry.

Synthesis and biological evaluation of celastrol derivatives as potential anti-glioma agents by activating RIP1/RIP3/MLKL pathway to induce necroptosis.

Yan-hua Mou, Yan Y. Zhang, Shaojie Wang, 2021, European journal of medicinal chemistry.

Valdecoxib: assessment of cyclooxygenase-2 potency and selectivity.

J. Gierse, C. Koboldt, K. Seibert, 2005, Journal of Pharmacology and Experimental Therapeutics.

3,4-Diarylthiophenes Are Selective COX-2 Inhibitors.

C. Koboldt, A. W. Veenhuizen, W. Perkins, 1996 .