P. Umbarkar

发表

Cardiomyocyte SMAD4-Dependent TGF-β Signaling is Essential to Maintain Adult Heart Homeostasis

T. Force, C. Galindo, V. Verma, 2019, JACC. Basic to translational science.

Mechanistic Insights of Empagliflozin-Mediated Cardiac Benefits: Nearing the Starting Line

P. Umbarkar, M. Gupte, H. Lal, 2017, Cardiovascular Drugs and Therapy.

Repurposing Nintedanib for Pathological Cardiac Remodeling and Dysfunction.

P. Sethu, Sultan Tousif, P. Umbarkar, 2021, Pharmacological research.

Repurposing Nintedanib for Pathological Cardiac Remodeling and Dysfunction

P. Sethu, Sultan Tousif, P. Umbarkar, 2020, bioRxiv.

Title: Repurposing Nintedanib for Pathological Cardiac Remodeling and Dysfunction First author’s surname: Umbarkar Short title: Nintedanib Prevents Adverse Myocardial Fibrosis Authors:

P. Umbarkar, A. Singh, H. Lal, 2020 .

Isoform-Specific Role of GSK-3 in High Fat Diet Induced Obesity and Glucose Intolerance

Sultan Tousif, P. Umbarkar, M. Gupte, 2022, Cells.

Deletion of Cardiomyocyte Glycogen Synthase Kinase-3 Beta (GSK-3β) Improves Systemic Glucose Tolerance with Maintained Heart Function in Established Obesity

P. Umbarkar, A. Singh, M. Gupte, 2020, Cells.

Cardiac fibroblast GSK-3α mediates adverse myocardial fibrosis via IL-11 and ERK pathway

Sultan Tousif, P. Umbarkar, A. Singh, 2021, bioRxiv.

Targeting 5-HT2B Receptor Signaling Prevents Border Zone Expansion and Improves Microstructural Remodeling after Myocardial Infarction.

A. Mahadevan-Jansen, A. Hatzopoulos, M. Bersi, 2021, Circulation.

The BDNF rs6265 Polymorphism is a Modifier of Cardiomyocyte Contractility and Dilated Cardiomyopathy

Joseph T. Roland, M. Buchowski, A. Hatzopoulos, 2020, International journal of molecular sciences.

Fibroblast GSK-3α Promotes Fibrosis via RAF-MEK-ERK Pathway in the Injured Heart

J. Woodgett, Sultan Tousif, M. Tallquist, 2022, Circulation research.

Entanglement of GSK-3β, β-catenin and TGF-β1 signaling network to regulate myocardial fibrosis.

T. Force, P. Umbarkar, A. Singh, 2017, Journal of molecular and cellular cardiology.

Monoamine oxidase-A is an important source of oxidative stress and promotes cardiac dysfunction, apoptosis, and fibrosis in diabetic cardiomyopathy.

S. Bodhankar, P. Umbarkar, S. Sitasawad, 2015, Free radical biology & medicine.

Mechanisms of Fibroblast Activation and Myocardial Fibrosis: Lessons Learned from FB-Specific Conditional Mouse Models

Sultan Tousif, P. Umbarkar, H. Lal, 2021, Cells.

Cardiotoxicity of the BCR-ABL1 tyrosine kinase inhibitors: Emphasis on ponatinib.

Sultan Tousif, P. Umbarkar, A. Singh, 2020, International journal of cardiology.

Ponatinib-induced cardiotoxicity: delineating the signalling mechanisms and potential rescue strategies

T. Force, C. Galindo, P. Umbarkar, 2019, Cardiovascular research.

Ponatinib Drives Cardiotoxicity by S100A8/A9-NLRP3-IL-1β Mediated Inflammation

S. Prabhu, C. Galindo, Sultan Tousif, 2023, Circulation research.

A Pharmacovigilance Study of Hydroxychloroquine Cardiac Safety Profile: Potential Implication in COVID-19 Mitigation

Sultan Tousif, P. Umbarkar, A. Singh, 2020, Journal of clinical medicine.

GSK-3 at the heart of cardiometabolic diseases: Isoform-specific targeting is critical to therapeutic benefit.

Sultan Tousif, P. Umbarkar, H. Lal, 2023, Biochimica et biophysica acta. Molecular basis of disease.

Inhibition of GSK-3 to induce cardiomyocyte proliferation: a recipe for in situ cardiac regeneration

T. Force, P. Umbarkar, A. Singh, 2018, Cardiovascular research.

Cardiomyocyte-specific deletion of GSK-3β leads to cardiac dysfunction in a diet induced obesity model.

T. Force, P. Umbarkar, A. Singh, 2018, International journal of cardiology.

Cardiac fibroblast GSK-3α aggravates ischemic cardiac injury by promoting fibrosis, inflammation, and impairing angiogenesis

Sultan Tousif, P. Umbarkar, Qinkun Zhang, 2023, Basic Research in Cardiology.

Sustained Increases in Cardiomyocyte Protein O‐Linked β‐N‐Acetylglucosamine Levels Lead to Cardiac Hypertrophy and Reduced Mitochondrial Function Without Systolic Contractile Impairment

Chae-Myeong Ha, Jianhua Zhang, J. Chatham, 2023, Journal of the American Heart Association.

Mitochondrial Peroxiredoxin-3 protects against hyperglycemia induced myocardial damage in Diabetic cardiomyopathy.

P. Umbarkar, S. Sitasawad, Sarojini Singh, 2016, Free radical biology & medicine.