J. Wilkins

发表

Population Pharmacokinetic Analysis of Bintrafusp Alfa in Different Cancer Types

Y. Vugmeyster, Akash Khandelwal, P. Girard, 2019, Advances in Therapy.

Variability in the population pharmacokinetics of pyrazinamide in South African tuberculosis patients

H. McIlleron, Peter J. Smith, U. Simonsson, 2006, European Journal of Clinical Pharmacology.

Safety, Tolerability, and Pharmacokinetics of Ribavirin in Hepatitis C Virus-Infected Patients with Various Degrees of Renal Impairment

J. Grippo, K. Nieforth, P. Martin, 2013, Antimicrobial Agents and Chemotherapy.

Population Pharmacokinetics and Pharmacodynamics of Paclitaxel and Carboplatin in Ovarian Cancer Patients: A Study by the European Organization for Research and Treatment of Cancer-Pharmacology and Molecular Mechanisms Group and New Drug Development Group

H. Hollema, A. Boddy, D. Richel, 2007, Clinical Cancer Research.

Variability in the population pharmacokinetics of isoniazid in South African tuberculosis patients.

H. McIlleron, Peter J. Smith, U. Simonsson, 2011, British journal of clinical pharmacology.

Modeling Disease Progression in Acute Stroke Using Clinical Assessment Scales

F. Jonsson, M. Karlsson, K. Karlsson, 2010, The AAPS Journal.

Pharmacokinetics and Exposure-Efficacy Relationships of Omalizumab in Patients with Nasal Polyps.

T. Omachi, R. Schoemaker, Angelica L. Quartino, 2021, Pulmonary pharmacology & therapeutics.

Selection of the Recommended Phase 2 Dose for Bintrafusp Alfa, a Bifunctional Fusion Protein Targeting TGF‐β and PD‐L1

Y. Vugmeyster, Akash Khandelwal, I. Dussault, 2020, Clinical pharmacology and therapeutics.

Performance of the SAEM and FOCEI Algorithms in the Open‐Source, Nonlinear Mixed Effect Modeling Tool nlmixr

Mirjam N Trame, T. Post, R. Schoemaker, 2019, CPT: Pharmacometrics & Systems Pharmacology.

Systemic pharmacokinetics of indacaterol, an inhaled once-daily long-acting beta2-agonist, in different ethnic populations.

R. Woessner, Soichiro Matsushima, K. Sekiguchi, 2012, International journal of clinical pharmacology and therapeutics.

Translation of liver stage activity of M5717, a Plasmodium elongation factor 2 inhibitor: from bench to bedside

Akash Khandelwal, P. Alves, Ö. Yalkinoglu, 2022, Malaria journal.

Population Pharmacokinetics of Ipatasertib and Its Metabolite in Cancer Patients

R. Sane, N. Kotani, J. Wade, 2021, Journal of clinical pharmacology.

Characterization of exposure–response relationships of ipatasertib in patients with metastatic castration-resistant prostate cancer in the IPATential150 study

R. Sane, N. Kotani, J. Wade, 2022, Cancer Chemotherapy and Pharmacology.

Model-informed approach for risk management of bleeding toxicities for bintrafusp alfa, a bifunctional fusion protein targeting TGF-β and PD-L1

K. Venkatakrishnan, Y. Vugmeyster, Akash Khandelwal, 2022, Cancer Chemotherapy and Pharmacology.

Selection of the recommended phase 2 dose (RP2D) for M7824 (MSB0011359C), a bifunctional fusion protein targeting TGF-β and PD-L1.

Y. Vugmeyster, Akash Khandelwal, J. Gulley, 2018 .

Open innovation: Towards sharing of data, models and workflows

Mats O. Karlsson, Justin J. Wilkins, Klaus Romero, 2017, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

Population Pharmacokinetics of Rifampin in Pulmonary Tuberculosis Patients, Including a Semimechanistic Model To Describe Variable Absorption

Mats O. Karlsson, Radojka M. Savic, Goonaseelan Pillai, 2008, Antimicrobial Agents and Chemotherapy.

A drug and disease model for lixisenatide, a GLP‐1 receptor agonist in type 2 diabetes

J. Wilkins, C. Laveille, M. Dubar, 2014, Journal of clinical pharmacology.

Population Pharmacokinetics of Ethambutol in South African Tuberculosis Patients

Siv Jönsson, Mats O. Karlsson, Ulrika S. H. Simonsson, 2011, Antimicrobial Agents and Chemotherapy.

Single-dose pharmacokinetics and tolerability of oral delta-9- tetrahydrocannabinol in patients with amyotrophic lateral sclerosis.

M. Joerger, Markus Weber, J. Wilkins, 2012, Drug metabolism letters.

Pharmacometrics in tuberculosis: progress and opportunities.

H. McIlleron, U. Simonsson, E. Svensson, 2022, International journal of antimicrobial agents.

Changing Body Weight–Based Dosing to a Flat Dose for Avelumab in Metastatic Merkel Cell and Advanced Urothelial Carcinoma

Akash Khandelwal, P. Girard, J. Wade, 2019, Clinical pharmacology and therapeutics.

Population Pharmacokinetics and Pharmacodynamics of the Calcimimetic Etelcalcetide in Chronic Kidney Disease and Secondary Hyperparathyroidism Receiving Hemodialysis

JP Gibbs, J. Wilkins, A. Narayanan, 2016, CPT: pharmacometrics & systems pharmacology.

Nonlinear Mixed‐Effects Model Development and Simulation Using nlmixr and Related R Open‐Source Packages

Wenping Wang, Yuan Xiong, Mirjam N Trame, 2019, CPT: pharmacometrics & systems pharmacology.

NONMEMory: A run management tool for NONMEM

Justin J. Wilkins, J. Wilkins, 2005, Comput. Methods Programs Biomed..

The guard changes

J. Wilkins, 2020, Journal of Pharmacokinetics and Pharmacodynamics.

Consecutive-dose pharmacokinetics of rifapentine in patients diagnosed with pulmonary tuberculosis.

H. McIlleron, G Langdon, J J Wilkins, 2004, The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease.

Tools for Nonlinear Mixed-Effect Model Building and Diagnostics

Andrew C. Hooker, Mats O. Karlsson, E. Niclas Jonsson, 2014 .

Time‐Varying Clearance and Impact of Disease State on the Pharmacokinetics of Avelumab in Merkel Cell Carcinoma and Urothelial Carcinoma

Y. Vugmeyster, Akash Khandelwal, P. Girard, 2019, CPT: pharmacometrics & systems pharmacology.

An economic comparison of chloroquine and sulfadoxine-pyrimethamine as first-line treatment for malaria in South Africa: development of a model for estimating recurrent direct costs.

K. Barnes, J. Wilkins, P. Folb, 2002, Transactions of the Royal Society of Tropical Medicine and Hygiene.

Translation of liver stage activity of M5717, a Plasmodium elongation factor 2 inhibitor: from bench to bedside

Akash Khandelwal, P. Alves, Ö. Yalkinoglu, 2022, Malaria journal.

Effects of morphine and tramadol on somatic and visceral sensory function and gastrointestinal motility after abdominal surgery.

C. Wilder-Smith, L. Hill, J. Wilkins, 1999, Anesthesiology.

Evaluation of the nonparametric estimation method in nonmem VI: application to real data

Mats O. Karlsson, Radojka M. Savic, Justin J. Wilkins, 2009, Journal of Pharmacokinetics and Pharmacodynamics.

Causal chemoprophylactic activity of cabamiquine against Plasmodium falciparum in a controlled human malaria infection: a randomised, double-blind, placebo-controlled study in the Netherlands.

D. Fidock, Akash Khandelwal, Satish K. Dhingra, 2023, Lancet. Infectious Diseases (Print).

Training the next generation of pharmacometric modelers: a multisector perspective.

P. Bonate, B. Corrigan, M. Neely, 2023, Journal of pharmacokinetics and pharmacodynamics.

Population Pharmacokinetics of Rifapentine and Its Primary Desacetyl Metabolite in South African Tuberculosis Patients

L. Mcfadyen, H. McIlleron, Peter J. Smith, 2005, Antimicrobial Agents and Chemotherapy.