Jiaan Shao

发表

Enhanced anticancer activity by the combination of vinpocetine and sorafenib via PI3K/AKT/GSK-3β signaling axis in hepatocellular carcinoma cells

Hua-qing Liu, Chong Zhang, S. Dong, 2021, Anti-cancer drugs.

Transition-metal-free and facile synthesis of 3-alkynylpyrrole-2, 4-dicarboxylates from methylene isocyanides and propiolaldehyde

Jiankang Zhang, Jiaan Shao, Huajian Zhu, 2021, New Journal of Chemistry.

Metabolism guided optimization of peptidomimetics as non-covalent proteasome inhibitors for cancer treatment.

Yu-bo Zhou, Jia Li, Qian Yu, 2022, European journal of medicinal chemistry.

Design, synthesis and biological evaluation of novel tumor hypoxia-activated EGFR tyrosine kinase inhibitors.

Zongfu Pan, Jiankang Zhang, Jiaan Shao, 2022, Bioorganic chemistry.

Sequential [3+2] annulation reaction of prop-2-ynylsulfonium salts and hydrazonyl chlorides: synthesis of pyrazoles containing functional motifs.

Shourong Liu, Jiankang Zhang, Jiaan Shao, 2021, Chemical communications.

The reaction of prop-2-ynylsulfonium salts and sulfonyl-protected β-amino ketones to epoxide-fused 2-methylenepyrrolidines and S-containing pyrroles.

Jiankang Zhang, Jiaan Shao, Huajian Zhu, 2021, Chemical communications.

(2 + 1 + 1 + 1)-Annulation Reactions of Aryldiazonium Tetrafluoroborates with Sulfur Ylides to Polysubstituted Pyrazoles.

Jiankang Zhang, Jiaan Shao, Huajian Zhu, 2021, The Journal of organic chemistry.

Proteasome, a Promising Therapeutic Target for Multiple Diseases Beyond Cancer

Jiankang Zhang, Jiaan Shao, Rangxiao Zhuang, 2020, Drug design, development and therapy.

A natural anthraquinone derivative shikonin synergizes with AZD9291 against wtEGFR NSCLC cells through reactive oxygen species-mediated endoplasmic reticulum stress.

Chong Zhang, N. Lin, Zuo-yan Zhang, 2020, Phytomedicine : international journal of phytotherapy and phytopharmacology.

Recent advances and future perspectives of noncompetitive proteasome inhibitors.

Qian Yu, Jiaan Shao, Rangxiao Zhuang, 2023, Bioorganic chemistry.

Exploration of novel four-membered-heterocycle constructed peptidyl proteasome inhibitors with improved metabolic stability for cancer treatment.

G. Wei, Jia Li, Li-xin Gao, 2023, Bioorganic chemistry.

Immunoproteasome-selective inhibitors: future of autoimmune diseases?

Jiaan Shao, Rangxiao Zhuang, Ruoyu He, 2020, Future medicinal chemistry.

Exploration of novel dihydroquinoxalinone derivatives as EGFRL858R/T790M tyrosine kinase inhibitors for the treatment of non-small-cell lung cancer.

Zongfu Pan, Shourong Liu, Jiaan Shao, 2023, Bioorganic chemistry.

Discovery of novel hypoxia-activated, nitroimidazole constructed multi-target kinase inhibitors on the basis of AZD9291 for the treatment of human lung cancer.

Jiaan Shao, W. Cheng, Huajian Zhu, 2023, Bioorganic & Medicinal Chemistry.

Proteasome activation: A novel strategy for targeting undruggable intrinsically disordered proteins.

Jiaan Shao, Rangxiao Zhuang, Yu Cao, 2024, Bioorganic chemistry.