N. Asakawa

发表

Antitumor activity of a novel oral signal transducer and activator of transcription 3 inhibitor YHO‐1701

A. Asai, N. Ogo, F. Nishisaka, 2020, Cancer Science.

Synthesis and structure–activity relationship of a novel, non-hydroxamate series of TNF-α converting enzyme inhibitors

A. Tebben, B. W. King, M. Covington, 2007 .

Streptomycin alleviates irinotecan-induced delayed-onset diarrhea in rats by a mechanism other than inhibition of β-glucuronidase activity in intestinal lumen

I. Kato, K. Uchida, T. Yokokura, 2010, Cancer Chemotherapy and Pharmacology.

Characteristic amino acid distribution around segments unique to allergens.

R. Teshima, S. Mitaku, N. Sakiyama, 2010, Journal of biochemistry.

Secondary structure breakers and hairpin structures in myoglobin and hemoglobin

T. Tsuji, K. Imai, S. Mitaku, 2005 .

Novel Acrylonitrile Derivatives, YHO-13177 and YHO-13351, Reverse BCRP/ABCG2-Mediated Drug Resistance In Vitro and In Vivo

Y. Sugimoto, H. Hatano, R. Yamazaki, 2011, Molecular Cancer Therapeutics.

Preclinical Development Novel Acrylonitrile Derivatives , YHO-13177 and YHO-13351 , Reverse BCRP / ABCG 2-Mediated Drug Resistance In Vitro and In Vivo

Y. Sugimoto, H. Hatano, R. Yamazaki, 2011 .

Alpha,Beta-cyclic-beta-benzamido hydroxamic acids: Novel oxaspiro[4.4]nonane templates for the discovery of potent, selective, orally bioavailable inhibitors of tumor necrosis factor-alpha converting enzyme (TACE).

J. Trzăskos, W. Marshall, K. Vaddi, 2008, Bioorganic & medicinal chemistry letters.

2,4-Disubstituted piperidines as selective CC chemokine receptor 3 (CCR3) antagonists: synthesis and selectivity.

G. Trainor, M. Covington, C. Decicco, 2006, Bioorganic & medicinal chemistry letters.

Combretastatin A4 disodium phosphate-induced myocardial injury

Toshihide Kobayashi, M. Kuwahara, K. Uchida, 2016, Journal of toxicologic pathology.

4-Chlorocolchicine derivatives bearing a thiourea side chain at the C-7 position as potent anticancer agents

M. Ono, T. Sugimoto, T. Sasai, 2014 .

Discovery of low nanomolar non-hydroxamate inhibitors of tumor necrosis factor-alpha converting enzyme (TACE).

Soong-Hoon Kim, W. Pitts, M. Covington, 2007, Bioorganic & medicinal chemistry letters.

α,β-Cyclic-β-benzamido hydroxamic acids: Novel templates for the design, synthesis, and evaluation of selective inhibitors of TNF-α converting enzyme (TACE)

David D. Christ, K. Vaddi, M. Covington, 2008 .

An Asymmetric Synthesis of the Vitamin E Core by Pd Catalyzed Discrimination of Enantiotopic Alkene Faces

B. Trost, N. Asakawa, 1999 .

One-carbon ring-expansion of 2-substituted cyclohexanones via lithium- and magnesium β-oxido carbenoid rearrangement: a new synthesis of 2,7-disubstituted and 2,2,7-trisubstituted cycloheptanones

N. Asakawa, T. Satoh, Shu Tanaka, 2006 .

New method for generation of β-oxido carbenoid via ligand exchange reaction of sulfoxides: A versatile procedure for one-carbon homologation of carbonyl compounds

N. Asakawa, K. Yamakawa, T. Satoh, 1994 .

Synthesis and biological evaluation of 4-chlorocolchicine derivatives as potent anticancer agents with broad effective dosage ranges

M. Ono, T. Sugimoto, T. Sasai, 2012 .

Use of 1,1'-Binaphthalene-8,8'-diol as a Chiral Auxiliary for Asymmetric Michael Addition. Application to the Syntheses of Turmeronol A and B.

K. Fuji, Kiyoshi Tanaka, Masato Yoshida, 1999 .

Use of 8,8′-dihydroxy-1,1′-binaphthalene as a chiral auxiliary for asymmetric Diels-Alder cycloadditions

K. Fuji, Kiyoshi Tanaka, M. Nuruzzaman, 1997 .

1,1′-Binaphthalene-8,8′-diol as an efficient chiral controller: Highly enantioselective synthesis of optically active ketones

K. Fuji, Kiyoshi Tanaka, N. Asakawa, 1996 .

Intramolecular palladium-catalyzed allylic alkylation: enantio- and diastereoselective synthesis of [2.2.2] bicycles.

B. Trost, N. Asakawa, K. L. Sacchi, 2002, Organic letters.

Potent, exceptionally selective, orally bioavailable inhibitors of TNF-alpha Converting Enzyme (TACE): novel 2-substituted-1H-benzo[d]imidazol-1-yl)methyl)benzamide P1' substituents.

J. Trzăskos, K. Vaddi, M. Covington, 2008, Bioorganic & medicinal chemistry letters.

Kinetic study on the inhibition of acetylcholinesterase by 1-benzyl-4-[(5,6-dimethoxy-1-indanon)-2-yl]methylpiperidine hydrochloride (E2020).

T. Sato, N. Asakawa, S. Nochi, 1995, Biological & pharmaceutical bulletin.

Release behavior of poly(lactic acid-co-glycolic acid) implants containing phosphorothioate oligodeoxynucleotide.

T. Kato, M. Ishida, N. Asakawa, 1997, Biological & pharmaceutical bulletin.

SOSUI-GramN: high performance prediction for sub-cellular localization of proteins in Gram-negative bacteria

T. Tsuji, K. Imai, S. Mitaku, 2008, Bioinformation.

Characterization of cholyl-adenylate in rat liver microsomes by liquid chromatography/electrospray ionization-mass spectrometry.

M. Nagata, J. Goto, H. Oiwa, 1999, Analytical biochemistry.

Synthetic cationic amphiphile for liposome-mediated DNA transfection with less cytotoxicity.

T. Kato, N. Asakawa, K. Iwamoto, 1996, Biological & pharmaceutical bulletin.

Antitumor activity of a novel oral signal transducer and activator of transcription 3 inhibitor YHO‐1701

A. Asai, N. Ogo, F. Nishisaka, 2020, Cancer science.

AutoGPA: An Automated 3D-QSAR Method Based on Pharmacophore Alignment and Grid Potential Analysis

Seiichi Kobayashi, Junichi Goto, Noriaki Hirayama, 2012, International journal of medicinal chemistry.