Wufu Zhu

Pengwu Zheng, Wufu Zhu, Zhihui Zhou, 2019, Proceedings of the 2019 International Conference on Education Innovation and Economic Management (ICEIEM 2019).

Putative identification of components in Zengye Decoction and their effects on glucose consumption and lipogenesis in insulin-induced insulin-resistant HepG2 cells.

Xu Zhang, Z. Lan, Wufu Zhu, 2018, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

Design, synthesis, antiproliferative activity and docking studies of quinazoline derivatives bearing oxazole or imidazole as potential EGFR inhibitors

Shan Xu, Hehua Xiong, Pengwu Zheng, 2018 .

Biomineralized Cascade Enzyme-Encapsulated ZIF-8 Nanoparticles Combined with Antisense Oligonucleotides for Drug-Resistant Bacteria Treatment.

Pengwu Zheng, Wufu Zhu, Yijun Liu, 2022, ACS applied materials & interfaces.

Bioactivatable reductive cleavage of azobenzene for controlling functional dumbbell oligodeoxynucleotides.

Yujian He, Wufu Zhu, Ya Wu, 2019, Bioorganic chemistry.

Synthesis and Biological Evaluation of Novel 6‐Hydrazinyl‐2,4‐bismorpholino pyrimidine and 1,3,5‐Triazine Derivatives as Potential Antitumor Agents

P. Gong, Wufu Zhu, Yanfang Zhao, 2012, Archiv der Pharmazie.

Design, Synthesis, and Biological Evaluation of Novel Thienopyrimidine Derivatives as PI3Kα Inhibitors

Yuanying Fang, Pengwu Zheng, Wufu Zhu, 2019, Molecules.

Design, synthesis and pharmacological evaluation of 2-arylurea-1,3,5-triazine derivative (XIN-9): A novel potent dual PI3K/mTOR inhibitor for cancer therapy.

Linxiao Wang, Shan Xu, Pengwu Zheng, 2022, Bioorganic chemistry.

An updated patent review of small-molecule c-Met kinase inhibitors (2018-present)

Wufu Zhu, Qingshan Pan, Zixuan Rao, 2021, Expert opinion on therapeutic patents.

Design, synthesis, and antitumor evaluation of quinoline‐imidazole derivatives

Lujie Cao, Shan Xu, Xiuying Chen, 2018, Archiv der Pharmazie.

Design, synthesis, biological evaluation and docking studies of novel 2-substituted-4-morpholino-7,8-dihydro-5H-thiopyrano[4,3-d]pyrimidine derivatives as dual PI3Kα/mTOR inhibitors.

Chen Chen, Linxiao Wang, Shan Xu, 2016, European journal of medicinal chemistry.

Pyrrole‐based EGFR inhibitors for the treatment of NCSLC: Binding modes and SARs investigations

Wufu Zhu, Jie He, Feiyi Yang, 2022, Chemical biology & drug design.

Ligustrazine modulates renal cysteine biosynthesis in rats exposed to cadmium.

Xu Zhang, Z. Lan, Wufu Zhu, 2017, Environmental toxicology and pharmacology.

Research Progress of Small Molecule VEGFR/c-Met Inhibitors as Anticancer Agents (2016–Present)

Pengwu Zheng, Wufu Zhu, Qian Zhang, 2020, Molecules.

Design, synthesis and biological evaluation of substituted 2-(thiophen-2-yl)-1,3,5-triazine derivatives as potential dual PI3Kα/mTOR inhibitors.

Qingqing Jin, Shan Xu, Pengwu Zheng, 2019, Bioorganic chemistry.

Discovery of novel pyrrolopyrimidine/pyrazolopyrimidine derivatives bearing 1,2,3‐triazole moiety as c‐Met kinase inhibitors

Linxiao Wang, Xiaobo Liu, Qidong Tang, 2018, Chemical biology & drug design.

Discovery of novel pyrrolo-pyridine/pyrimidine derivatives bearing pyridazinone moiety as c-Met kinase inhibitors.

L. Wang, Shan Xu, Xiaobo Liu, 2017, European journal of medicinal chemistry.

Design, synthesis and biological evaluation of novel 4-anlinoquinazoline derivatives as EGFR inhibitors with the potential to inhibit the gefitinib-resistant nonsmall cell lung cancers

Hong Zhang, Shan Xu, Pengwu Zheng, 2018, Journal of enzyme inhibition and medicinal chemistry.

Synthesis and antiproliferative activity of 6,7-disubstituted-4-phenoxyquinoline derivatives bearing the 1,8-naphthyridin-2-one moiety.

P. Gong, Linxiao Wang, Hehua Xiong, 2018, European journal of medicinal chemistry.

Design, synthesis and evaluation of anti-proliferative activity of 2-aryl-4-aminoquinazoline derivatives as EGFR inhibitors.

Shan Xu, Pengwu Zheng, Wufu Zhu, 2021, Bioorganic chemistry.

Design, synthesis, anticancer activity and docking studies of novel 4-morpholino-7,8-dihydro-5H-thiopyrano[4,3-d]pyrimidine derivatives as mTOR inhibitors.

Shan Xu, Pengwu Zheng, Wufu Zhu, 2014, Bioorganic & medicinal chemistry.

Design,synthesis and biological evaluation of new rhodacyanine analogues as potential antitumor agents

X. Zhai, P. Gong, Wufu Zhu, 2012 .

Discovery of Triazolo-pyridazine/-pyrimidine Derivatives Bearing Aromatic (Heterocycle)-Coupled Azole Units as Class II c-Met Inhibitors

Wenhui Gan, Shan Xu, Xiaobo Liu, 2020, ACS omega.

Discovery of novel pyrrolo[2,3-b]pyridine derivatives bearing 1,2,3-triazole moiety as c-Met kinase inhibitors.

P. Gong, Linxiao Wang, Qidong Tang, 2016, Bioorganic & medicinal chemistry letters.

Design and synthesis of novel pyrimido[5,4-d]pyrimidine derivatives as GPR119 agonist for treatment of type 2 diabetes.

Yi Jin, Yuanying Fang, Wufu Zhu, 2018, Bioorganic & medicinal chemistry.

Discovery of novel 6,7-disubstituted-4-phenoxyquinoline derivatives bearing 5-(aminomethylene)pyrimidine-2,4,6-trione moiety as c-Met kinase inhibitors.

M. Cheng, P. Gong, Qidong Tang, 2014, Bioorganic & medicinal chemistry.

Design, synthesis and antitumor activity of Novel Sorafenib derivatives bearing pyrazole scaffold.

Min Wang, Shan Xu, Pengwu Zheng, 2017, Bioorganic & medicinal chemistry.

Design, synthesis and antitumor activity of novel artemisinin derivatives using hybrid approach.

X. Zhai, Wufu Zhu, Yanfang Zhao, 2011, Chemical & pharmaceutical bulletin.

Multifunctional MIL-101 Nanoparticles with Fenton-like Reactions to Co-deliver LL-37 Peptide and Vancomycin for Targeted NIR Imaging and Drug-resistant Bacteria Treatment

Y. Zhang, Tianyue Zhou, Shan Xu, 2022, Chemical Engineering Journal.

(E)-3-(dimethylamino)-1-(1H-indol-3-yl)prop-2-en-1-one

Wensheng Zou, Wufu Zhu, Shuang Jia, 2018 .

XS-2, a novel potent dual PI3K/mTOR inhibitor, exhibits high in vitro and in vivo anti-breast cancer activity and low toxicity with the potential to inhibit the invasion and migration of triple-negative breast cancer.

Zhiyan Jiang, Q. Guo, Daiying Zuo, 2022, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.

Design, Synthesis, and Biological Evaluation of [1,2,4]triazolo[4,3-a] Pyrazine Derivatives as Novel Dual c-Met/VEGFR-2 Inhibitors

Xiaobo Liu, Pengwu Zheng, Wufu Zhu, 2022, Frontiers in Chemistry.

Synthesis and Anticancer Activity Of One Novel Thiopyrano[4,3-D]Pyrimidine Derivative Bearing A Indole-hydrazone

Chen Chen, Shan Xu, Pengwu Zheng, 2015 .

Synthesis and Biological Evaluation of Novel 8-Morpholinoimidazo[1,2-a]pyrazine Derivatives Bearing Phenylpyridine/Phenylpyrimidine-Carboxamides

Chen Chen, Yong Zhou, Shan Xu, 2017, Molecules.

Design, synthesis and docking studies of novel thienopyrimidine derivatives bearing chromone moiety as mTOR/PI3Kα inhibitors.

Chen Chen, Shan Xu, Pengwu Zheng, 2015, European journal of medicinal chemistry.

Design, Synthesis and Anticancer Activity of 4-Morpholinothieno[3,2-D]-Pyrimidine Derivatives Bearing Chromone Moiety

Pengwu Zheng, Wufu Zhu, Chunjiang Wu, 2014, CIT 2014.

Epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors for the treatment of non-small cell lung cancer: a patent review (2014-present)

Shan Xu, Pengwu Zheng, Wufu Zhu, 2020, Expert opinion on therapeutic patents.

Design, synthesis and 3D-QSAR analysis of novel thiopyranopyrimidine derivatives as potential antitumor agents inhibiting A549 and Hela cancer cells.

Z. Lan, Shan Xu, Pengwu Zheng, 2019, European journal of medicinal chemistry.

Design, Synthesis, and Antitumor Activity of Olmutinib Derivatives Containing Acrylamide Moiety

Shan Xu, Pengwu Zheng, Wufu Zhu, 2021, Molecules.

Discovery of thiapyran-pyrimidine derivatives as potential EGFR inhibitors.

Shan Xu, Pengwu Zheng, Wufu Zhu, 2020, Bioorganic & medicinal chemistry.

Design, synthesis and antitumor activity of novel thiophene-pyrimidine derivatives as EGFR inhibitors overcoming T790M and L858R/T790M mutations.

Liying Yu, Shan Xu, Pengwu Zheng, 2020, European journal of medicinal chemistry.

Design, Synthesis and Biological Evaluation of 4-Phenoxy- Pyridine/Pyrimidine Derivatives as Dual VEGFR-2/c-Met Inhibitors

Pengwu Zheng, Wufu Zhu, Qian Zhang, 2022, New Journal of Chemistry.

Hydroxypropyl-β-cyclodextrin functionalized calcium carbonate microparticles as a potential carrier for enhancing oral delivery of water-insoluble drugs

Liqun Jiang, Wufu Zhu, Yanzhuo Zhang, 2015, International journal of nanomedicine.

Synthesis and Evaluation of Mesoporous Carbon/Lipid Bilayer Nanocomposites for Improved Oral Delivery of the Poorly Water-Soluble Drug, Nimodipine

Qinfu Zhao, Wufu Zhu, Yanzhuo Zhang, 2015, Pharmaceutical Research.

Design, synthesis and 3D-QSAR analysis of novel 2-hydrazinyl-4-morpholinothieno[3,2-d]pyrimidine derivatives as potential antitumor agents.

X. Zhai, Hongyu Zhou, Di Wu, 2012, European journal of medicinal chemistry.

Synthesis and cytotoxic activity of novel 2,6-disubstituted-4-mor-pholinothieno[3,2-d]pyrimidines as potent anti-tumor agents

X. Zhai, P. Gong, Wufu Zhu, 2012 .

Synthesis and bioevaluation and doking study of 1H-pyrrolo[2,3-b]pyridine derivatives bearing aromatic hydrazone moiety as c-Met inhibitors.

Shan Xu, Xiaobo Liu, Pengwu Zheng, 2017, European journal of medicinal chemistry.

Synthesis, and docking studies of phenylpyrimidine-carboxamide derivatives bearing 1H-pyrrolo[2,3-b]pyridine moiety as c-Met inhibitors.

Shan Xu, Qidong Tang, Pengwu Zheng, 2016, Bioorganic & medicinal chemistry.

Design, synthesis, and docking studies of phenylpicolinamide derivatives bearing 1H-pyrrolo[2,3-b]pyridine moiety as c-Met inhibitors.

Ping Gong, Min Wang, P. Gong, 2016, Bioorganic & medicinal chemistry.

Synthesis of One Novel Thieno[2,3-D]Pyrimidine Derivative Bearing a Sulfonylurea Moiety

C. Chen, Shan Xu, Pengwu Zheng, 2014 .

Design, Synthesis, and Biological Evaluation of Sorafenib Analogs Bearing a Sulfonylurea Unit as Novel VEGFR2 Kinase Inhibitors

Shan Xu, Pengwu Zheng, Wufu Zhu, 2014, CIT 2014.

Synthesis and bioevaluation of thienopyrimidines bearing a pyrazoline unit as selective PI3Kα inhibitors

Zixin Luo, Shan Xu, Wufu Zhu, 2019, RSC Advances.

Synthesis and bioevaluation study of novel N-methylpicolinamide and thienopyrimidine derivatives as selectivity c-Met kinase inhibitors.

Linxiao Wang, Shan Xu, Xiaobo Liu, 2018, Bioorganic & medicinal chemistry.

Synthesis and Structure–Activity Relationships of 4-Morpholino-7,8-Dihydro-5H-Thiopyrano[4,3-d]pyrimidine Derivatives Bearing Pyrazoline Scaffold

Shan Xu, Pengwu Zheng, Wufu Zhu, 2017, Molecules.

Design, synthesis and biological evaluation of AZD9291 derivatives as selective and potent EGFRL858R/T790M inhibitors.

Yanzhuo Zhang, Z. Lan, Shan Xu, 2019, European journal of medicinal chemistry.

Synthesis of 4-(2-(Piperazin-1-Yl)-7,8-Dihydro-5H-Thiopyrano[4,3-d]Pyrimidin-4-yl)Morpholine and 4-Morpholino-2-(Piperazin-1-Yl)- 7,8-Dihydro-5H-Thiopyrano[4,3-d]Pyrimidine 6,6-Dioxide

Shan Xu, Pengwu Zheng, Wufu Zhu, 2014 .

Design, synthesis and anticancer activity of 4-morpholinothieno[3,2-d]pyrimidine derivatives bearing arylmethylene hydrazine moiety.

X. Zhai, P. Gong, Wufu Zhu, 2012, Chemical & pharmaceutical bulletin.

Synthesis and Evaluation of Mesoporous Carbon/Lipid Bilayer Nanocomposites for Improved Oral Delivery of the Poorly Water-Soluble Drug, Nimodipine

Qinfu Zhao, Wufu Zhu, Yanzhuo Zhang, 2015, Pharmaceutical Research.

NIR responsive composite nanomaterials with in-situ deposition of cascaded nanozymes for multiple synergistic therapy of bacterial infection in diabetic mice

Qi Guo, Xuan Zhang, Shan Xu, 2023, Chemical Engineering Journal.

Design, synthesis and biological evaluation of 4-(4-aminophenoxy)picolinamide derivatives as potential antitumor agents.

Meng Liu, Dongxue Fu, Linxiao Wang, 2023, European journal of medicinal chemistry.

Design, Synthesis and Biological Evaluation of Novel Phenylsulfonylurea Derivatives as PI3K/mTOR Dual Inhibitors

Shan Xu, Wufu Zhu, Wei Li, 2018, Molecules.

Synthesis and antiproliferative activity of pyrrolo[2,3-b]pyridine derivatives bearing the 1,8-naphthyridin-2-one moiety.

Min Wang, P. Gong, Linxiao Wang, 2018, European journal of medicinal chemistry.

Design, synthesis and activity of novel sorafenib analogues bearing chalcone unit.

Chunjiang Wu, Min Wang, Shan Xu, 2016, Bioorganic & medicinal chemistry letters.

Thiazole-based analogues as potential antibacterial agents against methicillin-resistant Staphylococcus aureus (MRSA) and their SAR elucidation.

Qidong Tang, Wufu Zhu, Zhouling Xie, 2023, European journal of medicinal chemistry.

Design, Synthesis and Antitumor Activity of Quinazoline Derivatives Bearing 2,3-Dihydro-indole or 1,2,3,4-Tetrahydroquinoline

Hong Zhang, Xiuying Chen, Pengwu Zheng, 2019, Letters in Drug Design & Discovery.

Synthesis of N-4-(4-chloro-3-trifluoromethyl-phenyl)-7-methoxy- Quinazoline - 4, 6- diamine

C. Chen, Shan Xu, Wufu Zhu, 2016 .

Discovery of [1,2,4]triazolo[4,3-a]pyrazine derivatives bearing a 4-oxo-pyridazinone moiety as potential c-Met kinase inhibitors

Shan Xu, Xiaobo Liu, Hehua Xiong, 2020, New Journal of Chemistry.

Synthesis and bioevaluation and doking study of 1H-pyrrolo[2,3-b]pyridine derivatives bearing aromatic hydrazone moiety as c-Met inhibitors.

Shan Xu, Xiaobo Liu, Pengwu Zheng, 2017, European journal of medicinal chemistry.

Synthesis, activity and docking studies of phenylpyrimidine-carboxamide Sorafenib derivatives.

Xiaobo Liu, Pengwu Zheng, Wufu Zhu, 2016, Bioorganic & medicinal chemistry.

Discovery of novel potent PI3K/mTOR dual‐target inhibitors based on scaffold hopping: Design, synthesis, and antiproliferative activity

Shan Xu, Qidong Tang, Wufu Zhu, 2023, Archiv der Pharmazie.

Novel quinazoline-based dual EGFR/c-Met inhibitors overcoming drug resistance for the treatment of NSCLC: Design, synthesis and anti-tumor activity.

Pengwu Zheng, Wufu Zhu, Han Zhang, 2023, Bioorganic chemistry.

Design, synthesis, and docking studies of quinazoline analogues bearing aryl semicarbazone scaffolds as potent EGFR inhibitors.

Jiaqian Han, Z. Lan, Shan Xu, 2017, Bioorganic & medicinal chemistry.

Pyrrole-containing hybrids as potential anticancer agents: An insight into current developments and structure-activity relationships.

Wufu Zhu, Zhihui Zhou, Han Zhang, 2024, European journal of medicinal chemistry.

Space-confined nanozyme with cascade reaction based on PCN-224 for synergistic bacterial infection treatment and NIR fluorescence imaging of wound bacterial infections

Linxiao Wang, Wufu Zhu, Qingshan Pan, 2024, Chemical Engineering Journal.

Light-responsive Au@Zn-TCPP nanozyme functionalized with cell-penetrating peptide and antisense oligonucleotide for sensing living bacteria and synergistic therapy of diabetic wounds

Wufu Zhu, Qingshan Pan, Yijun Liu, 2024, Chemical Engineering Journal.

Coordination-Driven Self-Assembly of Metal Ion-Antisense Oligonucleotide Nanohybrids for Chronic Bacterial Infection Therapy.

Wufu Zhu, Qingshan Pan, Rujue Peng, 2024, ACS applied materials & interfaces.

Synthesis and Biological Evaluation of Novel 4-Morpholino-7,8-dihydro-5H-thiopyrano[4,3-d]pyrimidine Derivatives Bearing Phenylpyridine/ Phenylpyrimidine-Carboxamides

Pengwu Zheng, Wufu Zhu, Wenhui Wang, 2016, Molecules.

Novel bioactive 2‐phenyl‐4‐aminopyrimidine derivatives as EGFRDel19/T790M/C797S inhibitors for the treatment of non‐small cell lung cancer

Wufu Zhu, Zhihui Zhou, Jie He, 2023, Archiv der Pharmazie.

A Novel Dual PI3K/mTOR Inhibitor, XIN-10, for the Treatment of Cancer

Wufu Zhu, Xin Sun, Shanshan Xu, 2023, International journal of molecular sciences.

T6496 targeting EGFR mediated by T790M or C797S mutant: machine learning, virtual screening and bioactivity evaluation study.

Linxiao Wang, Wufu Zhu, Y. Tu, 2024, Journal of biomolecular structure & dynamics.

T5S1607 identified as a antibacterial FtsZ inhibitor：Virtual screening combined with bioactivity evaluation for the drug discovery

Linxiao Wang, Qidong Tang, Wufu Zhu, 2023, Comput. Biol. Chem..

Editorial: Different cell death modes in cancer treatment

Wufu Zhu, T. Saleh, Jingwen Xu, 2023, Frontiers in pharmacology.

A patent review of small molecule CDK4/6 inhibitors in the treatment of cancer: 2020-present.

Wufu Zhu, Shidi Xu, Lei Duan, 2024, Expert opinion on therapeutic patents.

Fragment-Based Anti-inflammatory Agent Design and Target Identification: Discovery of AF-45 as an IRAK4 Inhibitor to Treat Ulcerative Colitis and Acute Lung Injury.

Wufu Zhu, Ying Zhou, Xiemin Wang, 2024, Journal of medicinal chemistry.