J. L. Aceña

发表

Fluorine in pharmaceutical industry: fluorine-containing drugs introduced to the market in the last decade (2001-2011).

Hong Liu, Jiang Wang, C. del Pozo, 2014, Chemical reviews.

A convenient approach to the aminocyclitol fragment of pancratistatin from 7-oxanorbornenes

J. L. Aceña, O. Arjona, F. Iradier, 1996 .

Sustainable Synthesis of Oximes, Hydrazones, and Thiosemicarbazones under Mild Organocatalyzed Reaction Conditions.

J. L. Aceña, J. L. García Ruano, Sara Morales, 2016, The Journal of organic chemistry.

Inexpensive chemical method for preparation of enantiomerically pure phenylalanine

I. Ojima, H. Moriwaki, V. Soloshonok, 2014, Amino Acids.

Asymmetric synthesis of α-amino acids via homologation of Ni(II) complexes of glycine Schiff bases; Part 1: alkyl halide alkylations

H. Moriwaki, V. Soloshonok, J. L. Aceña, 2013, Amino Acids.

A comprehensive examination of the self-disproportionation of enantiomers (SDE) of chiral amides via achiral, laboratory-routine, gravity-driven column chromatography

Yuya Suzuki, K. Klika, Jianlin Han, 2015 .

Recent Progress in the in situ Detrifluoroacetylative Generation of Fluoro Enolates and Their Reactions with Electrophiles

G. Röschenthaler, Haibo Mei, Jianlin Han, 2015 .

The self-disproportionation of the enantiomers (SDE) of methyl n-pentyl sulfoxide via achiral, gravity-driven column chromatography: a case study.

K. Klika, V. Soloshonok, J. Drabowicz, 2014, Organic & biomolecular chemistry.

Small‐Molecule Therapeutics for Ebola Virus (EBOV) Disease Treatment

Hong Liu, Jiang Wang, V. Soloshonok, 2016 .

Asymmetric Mannich reaction between (S)-N-(tert-butanesulfinyl)-3,3,3-trifluoroacetaldimine and malonic acid derivatives. Stereodivergent synthesis of (R)- and (S)-3-amino-4,4,4-trifluorobutanoic acids.

V. Soloshonok, Etsuko Tokunaga, N. Shibata, 2014, Organic & biomolecular chemistry.

FM19G11 reverses endothelial dysfunction in rat and human arteries through stimulation of the PI3K/Akt/eNOS pathway, independently of mTOR/HIF‐1α activation

L. Rodríguez-Mañas, E. López-Hernández, J. Sánchez-Puelles, 2015, British journal of pharmacology.

Introducing a new radical trifluoromethylation reagent.

Jianlin Han, V. Soloshonok, J. L. Aceña, 2015, Chemical communications.

A new strategy for the synthesis of fluorinated 3,4-dihydropyrimidinones

C. Pozo, J. L. Aceña, S. Fustero, 2009 .

A study of graphene-based Cu-catalysts. Cu(I) nanoplatelets for batch and continuous-flow applications.

G. Romanazzi, C. Carlucci, L. Degennaro, 2019, Chemistry, an Asian journal.

Tailor-Made α-Amino Acids in the Pharmaceutical Industry: Synthetic Approaches to (1R,2S)-1-Amino-2-vinylcyclopropane-1-carboxylic Acid (Vinyl-ACCA)

Hong Liu, V. Soloshonok, J. L. Aceña, 2016 .

Chemical kinetic resolution of unprotected β-substituted β-amino acids using recyclable chiral ligands.

Hong Liu, Shengbin Zhou, Jiang Wang, 2014, Angewandte Chemie.

Quantitative analysis of ES-285, an investigational marine anticancer drug, in human, mouse, rat, and dog plasma using coupled liquid chromatography and tandem mass spectrometry.

J. Schellens, H. Rosing, J. Beijnen, 2003, Journal of mass spectrometry : JMS.

Biochemical quantitation of the eIF5A hypusination in Arabidopsis thaliana uncovers ABA-dependent regulation

J. Carbonell, A. Granell, J. Rambla, 2014, Front. Plant Sci..

Asymmetric Synthesis of (2S,3S)-α-(1-Oxoisoindolin-3-yl)glycines under Low-Basicity "Kinetic" Control.

Hong Liu, Shengbin Zhou, Jiang Wang, 2015, The Journal of organic chemistry.

Chemical Dynamic Thermodynamic Resolution and S/R Interconversion of Unprotected Unnatural Tailor-made α-Amino Acids.

Hong Liu, Shengbin Zhou, Jiang Wang, 2015, The Journal of organic chemistry.

Asymmetric synthesis of fluorinated cyclic beta-amino acid derivatives through cross metathesis.

C. del Pozo, María Sánchez-Roselló, J. L. Aceña, 2006, Organic letters.

New fluorinated 1,3-vinylogous amidines as versatile intermediates: synthesis of fluorinated pyrimidin-2(1H)-ones

Benjamin H. Brodsky, María Sánchez-Roselló, J. L. Aceña, 2006 .

Advanced asymmetric synthesis of (1R,2S)-1-amino-2-vinylcyclopropanecarboxylic acid by alkylation/cyclization of newly designed axially chiral Ni(II) complex of glycine Schiff base

Hong Liu, Jiang Wang, H. Moriwaki, 2015, Amino Acids.

A general overview of the organocatalytic intramolecular aza-Michael reaction.

C. del Pozo, María Sánchez-Roselló, J. L. Aceña, 2014, Chemical Society reviews.

Next Generation of Fluorine-Containing Pharmaceuticals, Compounds Currently in Phase II-III Clinical Trials of Major Pharmaceutical Companies: New Structural Trends and Therapeutic Areas.

Wei Zhu, Hong Liu, Yu Zhou, 2016, Chemical reviews.

Stereoselective access to fluorinated and non-fluorinated quaternary piperidines: synthesis of pipecolic acid and iminosugar derivatives.

J. L. Aceña, S. Fustero, Javier Miró, 2012, Chemistry.

Recent advances in the trifluoromethylation methodology and new CF3-containing drugs

Hong Liu, Jiang Wang, V. Soloshonok, 2014 .

Organocatalytic anti‐Selective Mannich Reactions with Fluorinated Aldimines: Synthesis of anti‐γ‐Fluoroalkyl‐γ‐amino Alcohols

J. L. Aceña, S. Fustero, J. F. Sanz-Cervera, 2009 .

Cross-metathesis reactions as an efficient tool in the synthesis of fluorinated cyclic beta-amino acids.

C. del Pozo, María Sánchez-Roselló, J. L. Aceña, 2009, The Journal of organic chemistry.

Diastereoselective intramolecular additions of allyl- and propargylsilanes to iminium ions: synthesis of cyclic and bicyclic quaternary amino acids.

J. L. Aceña, S. Fustero, N. Mateu, 2010, Organic letters.

NH-type of chiral Ni(II) complexes of glycine Schiff base: design, structural evaluation, reactivity and synthetic applications.

C. Roussel, Jianlin Han, V. Soloshonok, 2014, Organic & biomolecular chemistry.

An Approach to 2,4-Substituted Pyrazolo[1,5-a]pyridines and Pyrazolo[1,5-a]azepines by Ring-Closing Metathesis

M. Maestro, J. L. Aceña, S. Fustero, 2013 .

Recent advances in the synthesis of fluorinated aminophosphonates and aminophosphonic acids

K. Turcheniuk, G. Röschenthaler, V. Soloshonok, 2013 .

Asymmetric Carbon–Carbon Bond Formation under Solventless Conditions in Ball Mills

Carsten Bolm, Vadim A. Soloshonok, C. Bolm, 2015 .

Asymmetric Synthesis of α‐Amino Acids under Operationally Convenient Conditions

Hong Liu, C. Bolm, V. Soloshonok, 2014 .

Recent advances in the synthesis of fluorinated aminophosphonates and aminophosphonic acids

K. Turcheniuk, G. Röschenthaler, V. Soloshonok, 2013 .

Unexpected One‐Pot Epoxy Sulfone—Enaminone Transformation. Synthesis of 5a‐Carba‐β‐mannopyranosylamine.

J. L. Aceña, O. Arjona, J. Plumet, 2010 .

Stereocontrolled Total Synthesis of (+)-Altohyrtin A/Spongistatin 1.

A. P. Hodgson, R. Oballa, K. Gibson, 2001, Angewandte Chemie.

Unexpected reactivity of graphene oxide with DBU and DMF

R. Sainz, A. Lamsabhi, J. L. Aceña, 2018 .

Fluorous TBAF: a convenient and selective reagent for fluoride-mediated deprotections.

J. L. Aceña, S. Fustero, J. F. Sanz-Cervera, 2009, The Journal of organic chemistry.

Synthesis of bis-α,α'-amino acids through diastereoselective bis-alkylations of chiral Ni(II)-complexes of glycine.

Hong Liu, Jiang Wang, H. Moriwaki, 2013, Organic & biomolecular chemistry.

Chiral N(H)‐tBu and N(H)‐Ad NiII Complexes of Glycine Schiff Bases: Deduction of a Mode of Kinetic Diastereoselectivity

M. Maestro, V. Soloshonok, J. L. Aceña, 2014 .

Synthesis and stereochemical assignments of diastereomeric Ni(II) complexes of glycine Schiff base with (R)-2-(N-{2-[N-alkyl-N-(1-phenylethyl)amino]acetyl}amino)benzophenone; a case of configurationally stable stereogenic nitrogen

I. Ojima, H. Moriwaki, V. Soloshonok, 2014, Beilstein journal of organic chemistry.

Alkylations of Chiral Nickel(II) Complexes of Glycine under Phase‐Transfer Conditions

V. Soloshonok, D. Houck, J. L. Aceña, 2012 .

Nitrogen-Containing OrganofluorineDerivatives: An Overview

María Sánchez-Roselló, J. L. Aceña, S. Fustero, 2009 .

Asymmetric synthesis of (1R,2S)-1-amino-2-vinylcyclopropanecarboxylic acid by sequential SN2–SN2′ dialkylation of (R)-N-(benzyl)proline-derived glycine Schiff base Ni(II) complex

Haibo Mei, H. Moriwaki, Jianlin Han, 2015 .

Design and synthesis of (S)- and (R)-α-(phenyl)ethylamine-derived NH-type ligands and their application for the chemical resolution of α-amino acids.

H. Moriwaki, V. Soloshonok, J. L. Aceña, 2014, Organic & biomolecular chemistry.

Asymmetric synthesis of α-amino acids via homologation of Ni(II) complexes of glycine Schiff bases. Part 3: Michael addition reactions and miscellaneous transformations

V. Soloshonok, J. L. Aceña, A. Sorochinsky, 2014, Amino Acids.

Synthesis of fluorine-containing α-amino acids in enantiomerically pure form via homologation of Ni(II) complexes of glycine and alanine Schiff bases

H. Moriwaki, V. Soloshonok, J. L. Aceña, 2013 .

Asymmetric synthesis of α-amino acids via homologation of Ni(II) complexes of glycine Schiff bases. Part 2: Aldol, Mannich addition reactions, deracemization and (S) to (R) interconversion of α-amino acids

H. Moriwaki, V. Soloshonok, J. L. Aceña, 2013, Amino Acids.

Chemical deracemization and (S) to (R) interconversion of some fluorine-containing α-amino acids

H. Moriwaki, V. Soloshonok, J. L. Aceña, 2013 .

Chemical approach for interconversion of (S)- and (R)-α-amino acids.

H. Moriwaki, V. Soloshonok, J. L. Aceña, 2013, Organic & biomolecular chemistry.

Design and synthesis of quasi-diastereomeric molecules with unchanging central, regenerating axial and switchable helical chirality via cleavage and formation of Ni(II)–O and Ni(II)–N coordination bonds

Jianlin Han, V. Soloshonok, J. L. Aceña, 2012, Beilstein journal of organic chemistry.

Synthesis of polysubstituted β-amino cyclohexane carboxylic acids via Diels–Alder reaction using Ni(II)-complex stabilized β-alanine derived dienes

Xiaomin Luo, Hualiang Jiang, Hong Liu, 2012, Amino Acids.

Cross-Metathesis Reactions as an Efficient Tool in the Synthesis of Fluorinated Cyclic β-Amino Acids.

María Sánchez-Roselló, C. Pozo, J. L. Aceña, 2009 .

Stereocontrolled Total Synthesis of (+)-Altohyrtin A/Spongistatin 1.

A. P. Hodgson, R. Oballa, K. Gibson, 2001, Angewandte Chemie.

Preparation of N -Sulfinyl Aldimines Using Pyrrolidine as Catalyst via Iminium Ion Activation

J. L. Aceña, Eduardo Rodrigo, Sara Morales, 2018, Organic Syntheses.

Recent Advances in the Asymmetric Synthesis of α-(Trifluoromethyl)-Containing α-Amino Acids

V. Soloshonok, J. L. Aceña, A. Sorochinsky, 2012 .

Studies in marine polypropionate synthesis: total synthesis of (-)-baconipyrone C.

I. Paterson, J. L. Aceña, A. Franklin, 2000, Organic letters.

Polypropionates from 7-oxanorbornene derivatives. A stereoselective and divergent synthesis of fragments with four contiguous chiral centers

J. L. Aceña, O. Arjona, J. Plumet, 1996 .

Chemical dynamic kinetic resolution and S/R interconversion of unprotected α-amino acids.

Hong Liu, H. Moriwaki, V. Soloshonok, 2014, Angewandte Chemie.

First Fluorous Synthesis of Fluorinated Uracils

C. Pozo, J. L. Aceña, S. Fustero, 2006 .

Role of the gem-difluoro moiety in the tandem ring-closing metathesis-olefin isomerization: regioselective preparation of unsaturated lactams.

C. del Pozo, María Sánchez-Roselló, J. L. Aceña, 2006, The Journal of organic chemistry.

A stereodivergent synthesis of (±)-cyclophellitol and (1R∗,6S∗)-cyclophellitol from the 7-oxabicyclo-[2.2.1]hept-5-ene-2-endo-carboxylic acid

J. L. Aceña, O. Arjona, J. Plumet, 1996 .

Total Syntheses of (+/-)-Cyclophellitol and (1R,6S)-Cyclophellitol.

J. L. Aceña, O. Arjona, J. Plumet, 1997, The Journal of organic chemistry.

A Stereodivergent Access to Naturally Occurring Aminocarba Sugars from (Phenylsulfonyl)-7-oxabicyclo[2.2.1]heptane Derivatives. Total Synthesis of Penta-N,O-Acetyl-(.+-.)-Validamine and Its C1 and C2 Stereoisomers

A. Viso, J. L. Aceña, O. Arjona, 1994 .

Strain-directed bridge cleavage of (phenylsulfonyl)-7-oxabicyclo[2.2.1]heptane derivatives: application to the total synthesis of carba-.alpha.-DL-glucopyranose

A. Viso, J. L. Aceña, O. Arjona, 1992 .

The stereocontrolled total synthesis of altohyrtin A/spongistatin 1: the southern hemisphere EF segment.

I. Paterson, M. J. Coster, J. L. Aceña, 2005, Organic & biomolecular chemistry.

Synthetic and biological applications of fluorous reagents as phase tags.

J. L. Aceña, S. Fustero, S. Catalán, 2012, Topics in current chemistry.

Recent Developments in the Synthesis of Fluorinated -Amino Acids

J. L. Aceña, S. Fustero, Antonio Simón-Fuentes, 2010 .

Carbonyl group coordination preferences in square-planar NiII and PdII complexes of pentadentate ligands by electron-withdrawing/donating substituents

H. Uekusa, K. Klika, Jianlin Han, 2015 .

Synthesis of Fluorinated β-AminoAcids

K. Mikami, V. Soloshonok, María Sánchez-Roselló, 2011 .

Self-disproportionation of enantiomers of non-racemic chiral amine derivatives through achiral chromatography

Vadim A. Soloshonok, Tsuyoshi Nakamura, V. Soloshonok, 2012 .

Total synthesis of (+)-7-deoxypancratistatin from furan.

J. L. Aceña, O. Arjona, M. León, 2000, Organic letters.

Asymmetric synthesis of α-amino acids via homologation of Ni(II) complexes of glycine Schiff bases; Part 1: alkyl halide alkylations

H. Moriwaki, V. Soloshonok, J. L. Aceña, 2013, Amino Acids.

A new and expeditious entry to 7-oxabicyclo[3.2.1]octan-8-ol and 2-oxabicyclo[3.3.1]nonan-9-ol skeletons via intramolecular Michael addition–SN2′ ring opening of 7-oxabicyclic sulfones

J. L. Aceña, O. Arjona, J. Plumet, 2000 .

Synthesis and biological evaluation of new bicyclic fluorinated uracils through ring-closing metathesis.

J. L. Aceña, S. Fustero, J. F. Sanz-Cervera, 2006, The Journal of organic chemistry.

The pHLIP system as a vehicle for microRNAs in the kidney

C. Fernández-Hernando, J. Vaquero, D. Rodríguez‐Puyol, 2020 .

The stereocontrolled total synthesis of altohyrtin A/spongistatin 1: fragment couplings, completion of the synthesis, analogue generation and biological evaluation.

I. Paterson, M. J. Coster, J. L. Aceña, 2005, Organic & biomolecular chemistry.

Synthesis and biological evaluation of spongistatin/altohyrtin analogues: E-ring dehydration and C46 side-chain truncation.

I. Paterson, M. J. Coster, J. L. Aceña, 2003, Chemical communications.

Asymmetric synthesis of α-amino acids via homologation of Ni(II) complexes of glycine Schiff bases. Part 3: Michael addition reactions and miscellaneous transformations

V. Soloshonok, J. L. Aceña, A. Sorochinsky, 2014, Amino Acids.

Tiratricol Neutralizes Bacterial Endotoxins and Reduces Lipopolysaccharide‐Induced TNF‐α Production in the Cell

E. Pérez-Payá, F. Albericio, J. L. Aceña, 2008, Chemical biology & drug design.

H. Moriwaki, V. Soloshonok, J. L. Aceña, 2013, Amino Acids.

Synthesis of (2S,3S)-β-(trifluoromethyl)-α,β-diamino acid by Mannich addition of glycine Schiff base Ni(II) complexes to N-tert-butylsulfinyl-3,3,3-trifluoroacetaldimine

G. Röschenthaler, H. Moriwaki, V. Soloshonok, 2015 .

Asymmetric synthesis of α-(1-oxoisoindolin-3-yl)glycine: synthetic and mechanistic challenges.

Hong Liu, Shengbin Zhou, Jiang Wang, 2015, Chemical communications.

Asymmetric Synthesis of α-Amino Acids via Homologation of Ni(II) Complexes of Glycine Schiff Bases. Part 1. Alkyl Halide Alkylations

H. Moriwaki, V. Soloshonok, J. L. Aceña, 2013 .

Unconventional preparation of racemic crystals of isopropyl 3,3,3-trifluoro-2-hydroxypropanoate and their unusual crystallographic structure: the ultimate preference for homochiral intermolecular interactions.

V. Soloshonok, José Luis Aceña, Vadim A Soloshonok, 2013, Chemical communications.

Optical purifications via self-disproportionation of enantiomers by achiral chromatography: case study of a series of α-CF3-containing secondary alcohols.

Alicja Wzorek, Taizo Ono, V. Soloshonok, 2013, Chirality.

Advanced asymmetric synthesis of (1R,2S)-1-amino-2-vinylcyclopropanecarboxylic acid by alkylation/cyclization of newly designed axially chiral Ni(II) complex of glycine Schiff base

Hong Liu, Jiang Wang, H. Moriwaki, 2016, Amino Acids.

Asymmetric Carbon—Carbon Bond Formation under Solventless Conditions in Ball Mills.

C. Bolm, V. Soloshonok, J. L. Aceña, 2015 .

Self-Disproportionation of Enantiomers of Chiral, Non-Racemic Fluoroorganic Compounds: Role of Fluorine as Enabling Element

Vadim A. Soloshonok, Alexander E. Sorochinsky, V. Soloshonok, 2012 .

Inexpensive chemical method for preparation of enantiomerically pure phenylalanine

I. Ojima, H. Moriwaki, V. Soloshonok, 2014, Amino Acids.

Next Generation of Fluorine-Containing Pharmaceuticals, Compounds Currently in Phase II-III Clinical Trials of Major Pharmaceutical Companies: New Structural Trends and Therapeutic Areas.

Hong Liu, Yu Zhou, Jiang Wang, 2016, Chemical Reviews.

Recent Advances in the Asymmetric Synthesis of α‐(Trifluoromethyl)‐Containing α‐Amino Acids

V. Soloshonok, J. L. Aceña, A. Sorochinsky, 2012 .

Fluorine in pharmaceutical industry: fluorine-containing drugs introduced to the market in the last decade (2001-2011).

Hong Liu, Jiang Wang, C. del Pozo, 2014, Chemical reviews.

A new strategy for the synthesis of fluorinated 3,4-dihydropyrimidinones

C. Pozo, J. L. Aceña, S. Fustero, 2009 .

I. Ojima, H. Moriwaki, V. Soloshonok, 2014, Beilstein journal of organic chemistry.

NH-type of chiral Ni(II) complexes of glycine Schiff base: design, structural evaluation, reactivity and synthetic applications.

C. Roussel, Jianlin Han, V. Soloshonok, 2014, Organic & biomolecular chemistry.

Chemical dynamic kinetic resolution and S/R interconversion of unprotected α-amino acids.

Hong Liu, H. Moriwaki, V. Soloshonok, 2014, Angewandte Chemie.

Chemical kinetic resolution of unprotected β-substituted β-amino acids using recyclable chiral ligands.

Hong Liu, Shengbin Zhou, Jiang Wang, 2014, Angewandte Chemie.

Assignment of absolute configuration on the basis of the conformational effects induced by chiral derivatizing agents: the 2-arylpyrrolidine case.

H. Broughton, Nuria Díaz, C. Pedregal, 2007, Organic letters.