Dongdong Li

发表

Synthesis, biological evaluation of novel 4,5-dihydro-2H-pyrazole 2-hydroxyphenyl derivatives as BRAF inhibitors.

Zhong-Chang Wang, Hai‐Liang Zhu, Yu-Shun Yang, 2012, Bioorganic & medicinal chemistry.

Design and synthesis of a novel series of N,4-diphenylpyrimidin-2-amine derivatives as potent and selective PI3Kγ inhibitors

Hai‐Liang Zhu, Huaiyu Yang, Dongdong Li, 2014 .

Design, synthesis, and initial evaluation of affinity-based small molecular probe for detection of WDR5.

Q. You, Zhengyu Jiang, Dongdong Li, 2018, Bioorganic chemistry.

A berberrubine-derived fluorescent probe for hydrazine and its practical application in water and food samples.

Dongdong Li, Ruo-Jun Man, Xiao-Wei Hu, 2021, Analytica chimica acta.

A turn-on fluorescent sensor for selective detection of hydrazine and its application in Arabidopsis thaliana.

Hai‐Liang Zhu, Yu-Shun Yang, Baozhong Wang, 2019, Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy.

Identification of novel B‐RafV600E inhibitors employing FBDD strategy

Zhong-Chang Wang, Peng-Fei Wang, Hai‐Liang Zhu, 2017, Biochemical pharmacology.

Novel Schiff‐Base‐Derived FabH Inhibitors with Dioxygenated Rings as Antibiotic Agents

Hai‐Liang Zhu, Jing Zhao, Dongdong Li, 2013, ChemMedChem.

Identification of novel JMJD2A inhibitor scaffold using shape and electrostatic similarity search combined with docking method and MM-GBSA approach

Fang Liu, Q. You, Dongdong Li, 2015 .

A novel indanone-derivated fluorescence sensor for Cysteine detection and biological imaging

Xiangyang Zhang, Yu-Shun Yang, Dongdong Li, 2020 .

Combined Molecular Docking, 3D‐QSAR, and Pharmacophore Model: Design of Novel Tubulin Polymerization Inhibitors by Binding to Colchicine‐binding Site

Ya-Juan Qin, Lin-Guo Zhao, Xin A. Zhang, 2015, Chemical biology & drug design.

Synthesis, Molecular Modeling and Biological Evaluation of 4-Alkoxyquinazoline Derivatives as Novel Inhibitors of VEGFR2.

Wenxue Sun, Dongdong Li, Ting-ting Zhao, 2016, Chemical & pharmaceutical bulletin.

Discovery of novel 1,3-diaryl pyrazolyl ester derivatives as COX-2 inhibitory candidates with anti-tumor effect

Yu-Shun Yang, Dongdong Li, Ruo-Jun Man, 2022, Journal of Molecular Structure.

A high selective colorimetric fluorescent probe for detection of silver ions in vitro and in vivo and its application on test strips.

Dongdong Li, Yong Qian, Huang Liu, 2022, Talanta.

Discovery of 6-substituted 4-anilinoquinazolines with dioxygenated rings as novel EGFR tyrosine kinase inhibitors.

Dongdong Li, Hai-bin Gong, Fei Fang, 2012, Bioorganic & medicinal chemistry letters.

Navigating into the chemical space between MGCD0103 and SAHA: novel histone deacetylase inhibitors as a promising lead

Xin A. Zhang, Pengcheng Lv, Dongdong Li, 2015 .

Novel 5-carboxy-8-HQ based histone demethylase JMJD2A inhibitors: introduction of an additional carboxyl group at the C-2 position of quinoline.

Q. You, J. Zhuang, Dongdong Li, 2015, European journal of medicinal chemistry.

Gold complexes of bis-indazole-derived N-Heterocyclic carbene: Synthesis, structural characterizations, and catalysis

Jing Chen, Yang Zhou, Tingting Xu, 2021 .

Design and synthesis of thiazole derivatives as potent FabH inhibitors with antibacterial activity.

Jing-Jun Dong, Dongdong Li, Fei Fang, 2014, European journal of medicinal chemistry.

Synthesis, molecular docking and evaluation of thiazolyl-pyrazoline derivatives as EGFR TK inhibitors and potential anticancer agents.

Qing-Shan Li, Zhu-Ping Xiao, Pengcheng Lv, 2011, Bioorganic & medicinal chemistry letters.

Novel 1,3,4-oxadiazole thioether derivatives targeting thymidylate synthase as dual anticancer/antimicrobial agents.

W. Zhong, Dongdong Li, Hai-bin Gong, 2013, Bioorganic & medicinal chemistry.

Discovery of 4,6-substituted-(diaphenylamino)quinazolines as potent c-Src inhibitors.

Dongdong Li, Fei Fang, Jian Sun, 2013, Organic & biomolecular chemistry.

Design, synthesis, biological evaluation, and molecular modeling study of 4-alkoxyquinazoline derivatives as potential VEGFR2 kinase inhibitors.

Dongdong Li, Fei Fang, Jian Sun, 2013, Organic & biomolecular chemistry.

Discovery of novel double pyrazole Schiff base derivatives as anti-tobacco mosaic virus (TMV) agents

Qing-Shan Li, Xianhai Lv, Zi-Li Ren, 2017 .

Synthesis, biological evaluation and molecular docking studies of pyrazole derivatives coupling with a thiourea moiety as novel CDKs inhibitors.

Xianhai Lv, Yong-Hua Yang, Yan-Ting Wang, 2013, European journal of medicinal chemistry.

Synthesis and antitumor activity of 1,2,4-triazoles having 1,4-benzodioxan fragment as a novel class of potent methionine aminopeptidase type II inhibitors.

Yankun Hou, Jing Zhao, Pengcheng Lv, 2011, Bioorganic & medicinal chemistry.

Synthesis and antifungal activity of nicotinamide derivatives as succinate dehydrogenase inhibitors.

Y. Ye, Jian-xin Wang, Yu Xiao, 2014, Journal of agricultural and food chemistry.

Design and synthesis of 4,6-substituted-(diaphenylamino)quinazolines as potent EGFR inhibitors with antitumor activity.

Dongdong Li, Xiang-Yong Lu, Huan-qiu Li, 2012, Bioorganic & medicinal chemistry.

Exploiting novel rotors with auxochromic dynamic motors for monitoring lysosomal viscosity

J. Gu, Yu-Shun Yang, Pengcheng Lv, 2020 .

Synthesis and antioxidant activity of novel Mannich base of 1,3,4-oxadiazole derivatives possessing 1,4-benzodioxan.

Haitian Ma, Y. Ye, Yu Xiao, 2013, Bioorganic & medicinal chemistry.

N-monosubstituted thiosemicarbazide as novel Ure inhibitors: synthesis, biological evaluation and molecular docking.

H. Ouyang, Weiwei Ni, Zhu-Ping Xiao, 2020, Future medicinal chemistry.

Discovery, design and synthesis of 6H-anthra[1,9-cd]isoxazol-6-one scaffold as G9a inhibitor through a combination of shape-based virtual screening and structure-based molecular modification.

Dong-Dong Li, Xiao-Li Xu, Wei-Lin Chen, 2016, Bioorganic & medicinal chemistry.

Design, synthesis and insecticidal activities of N-(4-cyano-1-phenyl-1H-pyrazol-5-yl)-1,3-diphenyl-1H-pyrazole-4-carboxamide derivatives

Xianhai Lv, Jinjing Xiao, Zi-Li Ren, 2015 .

Design, synthesis, and evaluation of substituted 6-amide-4-anilinoquinazoline derivatives as c-Src inhibitors

Dongdong Li, Hai-bin Gong, Fei Fang, 2013 .

Optimization of Substituted 6-Salicyl-4-Anilinoquinazoline Derivatives as Dual EGFR/HER2 Tyrosine Kinase Inhibitors

Ya-Juan Qin, Dongdong Li, Hai-bin Gong, 2013, PloS one.

Targeting protein-protein interaction between MLL1 and reciprocal proteins for leukemia therapy.

Q. You, Dongdong Li, Wei-lin Chen, 2018, Bioorganic & medicinal chemistry.

Structure-based design of ester compounds to inhibit MLL complex catalytic activity by targeting mixed lineage leukemia 1 (MLL1)-WDR5 interaction.

Q. You, Yi-Yue Xie, Dongdong Li, 2016, Bioorganic & medicinal chemistry.

Discovery of DDO-2213 as a Potent and Orally Bioavailable Inhibitor of the WDR5-Mixed Lineage Leukemia 1 Protein-Protein Interaction for the Treatment of MLL Fusion Leukemia.

Q. You, Zhengyu Jiang, Dongdong Li, 2021, Journal of medicinal chemistry.

Proton pump inhibitors selectively suppress MLL rearranged leukemia cells via disrupting MLL1-WDR5 protein-protein interaction.

Q. You, Zhengyu Jiang, Dongdong Li, 2019, European journal of medicinal chemistry.

The combination of 4-anilinoquinazoline and cinnamic acid: a novel mode of binding to the epidermal growth factor receptor tyrosine kinase.

Yankun Hou, Y. Ye, Pengcheng Lv, 2011, Bioorganic & medicinal chemistry.

Novel Tetrahydropyrido[4,3-d]pyrimidines as Potent Inhibitors of Chaperone Heat Shock Protein 90.

Lei Wang, Q. You, Dongdong Li, 2016, Journal of medicinal chemistry.

Discovery of pyrazole‐carbohydrazide with indole moiety as tubulin polymerization inhibitors and anti‐tumor candidates

Dongdong Li, Ruo-Jun Man, Meng-Ke Wu, 2022, Drug development research.

High-affinity small molecular blockers of mixed lineage leukemia 1 (MLL1)-WDR5 interaction inhibit MLL1 complex H3K4 methyltransferase activity.

Q. You, Zhengyu Jiang, Yi-Yue Xie, 2016, European journal of medicinal chemistry.

Structure-based design and synthesis of small molecular inhibitors disturbing the interaction of MLL1-WDR5.

Lei Wang, Q. You, Yi-Yue Xie, 2016, European journal of medicinal chemistry.

(E)-4-Chlorobenzyl 3-(3-nitrobenzylidene)dithiocarbazate

Yin Luo, Dongdong Li, Huan-qiu Li, 2009, Acta crystallographica. Section E, Structure reports online.

A fluorescent sensor for selective detection of hypochlorite and its application in Arabidopsis thaliana.

Baozhong Wang, Dongdong Li, Hailiang Zhu, 2020, Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy.

G9a - An Appealing Antineoplastic Target.

Q. You, Dongdong Li, Wei-lin Chen, 2017, Current cancer drug targets.

Discovery of a potent MLL1 and WDR5 protein-protein interaction inhibitor with in vivo antitumor activity.

Q. You, Zhengyu Jiang, Dongdong Li, 2021, European journal of medicinal chemistry.

Design, synthesis, biological evaluation, and molecular modeling study of 4-alkoxyquinazoline derivatives as potential VEGFR2 kinase inhibitors.

Dongdong Li, Fei Fang, Jian Sun, 2013, Organic & biomolecular chemistry.