J. Blevitt

发表

A highly selective, orally bioavailable, vascular endothelial growth factor receptor-2 tyrosine kinase inhibitor has potent activity in vitro and in vivo

Angel R. Fuentes-Pesquera, P. Connolly, Shenlin Huang, 2009, Angiogenesis.

Oxysterols are agonist ligands of RORγt and drive Th17 cell differentiation

A. Bittner, Jiejun Wu, T. Rao, 2014, Proceedings of the National Academy of Sciences.

Structural Basis of Small-Molecule Aggregate Induced Inhibition of a Protein-Protein Interaction.

Taraneh Mirzadegan, Michael D Hack, Alec D Lebsack, 2017, Journal of medicinal chemistry.

Dual binding site inhibitors of B-RAF kinase.

Jianmei Wei, L. Karlsson, J. Edwards, 2008, Bioorganic & medicinal chemistry letters.

A novel B-RAF inhibitor blocks interleukin-8 (IL-8) synthesis in human melanoma xenografts, revealing IL-8 as a potential pharmacodynamic biomarker

Jianmei Wei, L. Karlsson, J. Edwards, 2008, Molecular Cancer Therapeutics.

A Single Amino Acid Difference between Mouse and Human 5-Lipoxygenase Activating Protein (FLAP) Explains the Speciation and Differential Pharmacology of Novel FLAP Inhibitors*

M. Milla, T. Mirzadegan, M. Hack, 2016, The Journal of Biological Chemistry.

Coupling to Gq Signaling Is Required for Cardioprotection by an Alpha-1A-Adrenergic Receptor Agonist.

A. Baker, P. Simpson, M. Milla, 2018, Circulation research.

A highly efficient, high-throughput lipidomics platform for the quantitative detection of eicosanoids in human whole blood.

P. Dorrestein, Jiejun Wu, M. Milla, 2013, Analytical biochemistry.

Azabenzthiazole inhibitors of leukotriene A₄ hydrolase.

John J. M. Wiener, Cheryl A. Grice, A. Fourie, 2012, Bioorganic & medicinal chemistry letters.

A Fluorescence-Based High Throughput Screen for the Transporter Associated with Antigen Processing

M. Jackson, P. A. Peterson, C. Glass, 1999, Journal of biomolecular screening.

Checkpoint kinase inhibitors: SAR and radioprotective properties of a series of 2-arylbenzimidazoles.

L. Karlsson, A. Brunmark, Liming Huang, 2005, Journal of medicinal chemistry.

A cell adhesion peptide that supports tissue interactions on inert materials

M. Pierschbacher, K. Dickerson, J. Blevitt, 1993 .

[26] Therapeutic application of matrix biology

J. Tschopp, M. Pierschbacher, C. Mazur, 1994 .

The alpha‐helical rod domain of human lamins A and C contains a chromatin binding site.

K. Hasel, L. Gerace, H. Taniura, 1993, The EMBO journal.

p 55 CDC 25 is a nuclear protein required for the initiation of mitosis in human cells ( cell cycle / CDC 2 / CDC 25 / mitotic inducer )

K. Sadhu, P. Russell, J. Millar, 2022 .

2-Aryl benzimidazoles featuring alkyl-linked pendant alcohols and amines as inhibitors of checkpoint kinase Chk2.

L. Karlsson, M. Hack, A. Brunmark, 2007, Bioorganic & medicinal chemistry letters.

p55CDC25 is a nuclear protein required for the initiation of mitosis in human cells.

K. Sadhu, P. Russell, J. Millar, 1991, Proceedings of the National Academy of Sciences of the United States of America.

Cloning and pharmacological characterization of a fourth histamine receptor (H(4)) expressed in bone marrow.

Nicholas J. Carruthers, J. Pyati, T. Lovenberg, 2001, Molecular pharmacology.

Phosphoinositide 3-kinase gamma (PI3Kgamma) inhibitors for the treatment of inflammation and autoimmune disease.

Jennifer D. Venable, R. Thurmond, W. Fung-Leung, 2010, Recent patents on inflammation & allergy drug discovery.

Phosphoinositide 3-Kinase Gamma (PI3Kγ) Inhibitors for the Treatment of Inflammation and Autoimmune Disease

Jennifer D. Venable, R. Thurmond, W. Fung-Leung, 2010 .

RORγt and RORα signature genes in human Th17 cells

Tinghua Cao, Shanrong Zhao, W. Fung-Leung, 2017, PloS one.

High-throughput phenotypic screen identifies a new family of potent anti-amoebic compounds

R. Abagyan, Conall Sauvey, J. Blevitt, 2021, bioRxiv.

Structural analysis of the p62 complex, an assembly of O-linked glycoproteins that localizes near the central gated channel of the nuclear pore complex.

S. Müller, U. Aebi, B. Paschal, 1995, Molecular biology of the cell.

O-linked glycoproteins of the nuclear pore complex interact with a cytosolic factor required for nuclear protein import

L. Gerace, J. Blevitt, R. Sterne‐Marr, 1992, The Journal of cell biology.

Phenotyping drug polypharmacology via eicosanoid profiling of blood[S]

P. Dorrestein, Jiejun Wu, T. Rao, 2015, Journal of Lipid Research.

Identification of benzofuran central cores for the inhibition of leukotriene A(4) hydrolase.

Cheryl A. Grice, L. Karlsson, A. Fourie, 2013, Bioorganic & medicinal chemistry letters.

Polypharmacology of Small-Molecule Modulators of the 5-Lipoxygenase Activating Protein (FLAP) Observed via a High-throughput Lipidomics Platform

C. Dvorak, Jiejun Wu, M. Milla, 2016, Journal of biomolecular screening.

Accelerated healing of cardiovascular textiles promoted by an RGD peptide.

H Harasaki, M. Helmus, H. Harasaki, 1995, The Journal of heart valve disease.

Novel non-benzimidazole chk2 kinase inhibitors.

A. Brunmark, Liming Huang, J. Blevitt, 2006, Bioorganic & medicinal chemistry letters.

Polypharmacology of Small-Molecule Modulators of the 5-Lipoxygenase Activating Protein (FLAP) Observed via a High-throughput Lipidomics Platform

C. Dvorak, Jiejun Wu, M. Milla, 2016, Journal of biomolecular screening.