Nicholas Pagano

发表

The crystal structure of BRAF in complex with an organoruthenium inhibitor reveals a mechanism for inhibition of an active form of BRAF kinase.

Peng Xie, Ronen Marmorstein, Eric Meggers, 2009, Biochemistry.

Exploring Chemical Space with Organometallics: Ruthenium Complexes as Protein Kinase Inhibitors

G. E. Atilla‐Gokcumen, Douglas S. Williams, H. Bregman, 2007 .

An Automated Process for a Sequential Heterocycle/Multicomponent Reaction: Multistep Continuous Flow Synthesis of 5-(Thiazol-2-yl)-3,4-Dihydropyrimidin-2(1H)-ones

N. Cosford, A. Herath, Nicholas Pagano, 2011, Journal of Flow Chemistry.

Crystal Structure of the PIM2 Kinase in Complex with an Organoruthenium Inhibitor

S. Knapp, F. von Delft, J. Debreczeni, 2009, PloS one.

Exploring Chemical Space with Organometallics: Ruthenium Complexes as Protein Kinase Inhibitors

Seann P. Mulcahy, G. E. Atilla‐Gokcumen, Douglas S. Williams, 2007 .

Extremely Tight Binding of a Ruthenium Complex to Glycogen Synthase Kinase 3

S. Knapp, G. E. Atilla‐Gokcumen, E. Meggers, 2008, Chembiochem : a European journal of chemical biology.

Toward the development of a potent and selective organoruthenium mammalian sterile 20 kinase inhibitor.

S. Diamond, P. Gimotty, E. Meggers, 2009, Journal of medicinal chemistry.

Metal-mediated base pairing within the simplified nucleic acid GNA.

E. Meggers, Nicholas Pagano, Lilu Zhang, 2009, Organic and biomolecular chemistry.

GSK3β inhibition blocks melanoma cell/host interactions by downregulating N-cadherin expression and decreasing FAK phosphorylation

M. Herlyn, K. Smalley, E. Meggers, 2012, The Journal of investigative dermatology.

Organometallic Compounds with Biological Activity: A Very Selective and Highly Potent Cellular Inhibitor for Glycogen Synthase Kinase 3

G. E. Atilla‐Gokcumen, Douglas S. Williams, H. Bregman, 2006, Chembiochem : a European journal of chemical biology.

An integrated chemical biology approach reveals the mechanism of action of HIV replication inhibitors.

Nicholas D. P. Cosford, Li Yang, Peter Teriete, 2017, Bioorganic & medicinal chemistry.

Ruthenium half-sandwich complexes as protein kinase inhibitors: derivatization of the pyridocarbazole pharmacophore ligand.

R. Webster, Douglas S. Williams, H. Bregman, 2007, Organic & biomolecular chemistry.

Use of design of experiments to optimize high-throughput semipreparative LC and LC/MS methods.

J. Ellingboe, D. Cole, Nicholas Pagano, 2004, Journal of combinatorial chemistry.

From imide to lactam metallo-pyridocarbazoles: distinct scaffolds for the design of selective protein kinase inhibitors.

S. Diamond, H. Bregman, E. Meggers, 2009, Journal of Organic Chemistry.

Synthesis and anticancer activity of ruthenium half-sandwich complexes comprising combined metal centrochirality and planar chirality

E. Meggers, M. Sherlock, Nicholas Pagano, 2014 .

From imide to lactam metallo-pyridocarbazoles: distinct scaffolds for the design of selective protein kinase inhibitors.

S. Diamond, H. Bregman, E. Meggers, 2009, The Journal of organic chemistry.