Sandra Lightle

发表

Structural evidence for substrate‐induced synergism and half‐sites reactivity in biotin carboxylase

Grover L Waldrop, Igor Mochalkin, Chunhong Yan, 2008, Protein science : a publication of the Protein Society.

Comparative functional characterization of canine IgG subclasses.

A. Gonzales, J. Shelly, Yaqi Zhu, 2014, Veterinary immunology and immunopathology.

Crystal structure of LpxC from Pseudomonas aeruginosa complexed with the potent BB‐78485 inhibitor

I. Mochalkin, J. Knafels, Sandra Lightle, 2008, Protein science : a publication of the Protein Society.

Discovery of potent selective bioavailable phosphodiesterase 2 (PDE2) inhibitors active in an osteoarthritis pain model. Part II: optimization studies and demonstration of in vivo efficacy.

J. Pandit, C. Whitehead, Cindy Spessard, 2013, Bioorganic & medicinal chemistry letters.

Structure of a small‐molecule inhibitor complexed with GlmU from Haemophilus influenzae reveals an allosteric binding site

D. Bornemeier, I. Mochalkin, Sandra Lightle, 2008, Protein science : a publication of the Protein Society.

Characterization of substrate binding and catalysis in the potential antibacterial target N‐acetylglucosamine‐1‐phosphate uridyltransferase (GlmU)

N. Chirgadze, J. Ohren, Cindy Spessard, 2007, Protein science : a publication of the Protein Society.

Mutations within a human IgG2 antibody form distinct and homogeneous disulfide isomers but do not affect Fc gamma receptor or C1q binding

T. Oliphant, Sandra Lightle, J. Zobel, 2010, Protein science : a publication of the Protein Society.

Discovery of antibacterial biotin carboxylase inhibitors by virtual screening and fragment-based approaches.

Venkataraman Thanabal, J Richard Miller, Igor Mochalkin, 2009, ACS chemical biology.

Structure based design of an in vivo active hydroxamic acid inhibitor of P. aeruginosa LpxC.

J. Warmus, J. Bronstein, S. Murphy, 2012, Bioorganic & medicinal chemistry letters.

Discovery of potent, selective, bioavailable phosphodiesterase 2 (PDE2) inhibitors active in an osteoarthritis pain model, part I: transformation of selective pyrazolodiazepinone phosphodiesterase 4 (PDE4) inhibitors into selective PDE2 inhibitors.

Howard Miller, J. Pandit, C. Whitehead, 2013, Bioorganic & medicinal chemistry letters.

Expression, purification, characterization and crystallization of non- and phosphorylated states of JAK2 and JAK3 kinase domain.

A. Tomasselli, J. F. Schindler, J. Chrencik, 2010, Protein expression and purification.

The structure of the carboxyltransferase component of acetyl-coA carboxylase reveals a zinc-binding motif unique to the bacterial enzyme.

Grover L Waldrop, B. Finzel, G. Waldrop, 2006, Biochemistry.