P. Miller

发表

Optimization of the Urea Linker of Triazolopyridazine MMV665917 Results in a New Anticryptosporidial Lead with Improved Potency and Predicted hERG Safety Margin.

D. Griggs, J. E. Teixeira, C. Huston, 2021, Journal of medicinal chemistry.

Clinical and microbiologic efficacy of the piperazine-based drug lead MMV665917 in the dairy calf cryptosporidiosis model

D. Griggs, C. Huston, M. J. Meyers, 2018, PLoS neglected tropical diseases.

Identification of a potent benzoxaborole drug candidate for treating cryptosporidiosis

J. Gut, C. Huston, J. Plattner, 2019, Nature Communications.

A Novel Piperazine-Based Drug Lead for Cryptosporidiosis from the Medicines for Malaria Venture Open-Access Malaria Box

C. Huston, M. J. Meyers, J. Zambriski, 2018, Antimicrobial Agents and Chemotherapy.

Bicyclic azetidines kill the diarrheal pathogen Cryptosporidium in mice by inhibiting parasite phenylalanyl-tRNA synthetase

S. Schreiber, A. Wernimont, B. Melillo, 2020, Science Translational Medicine.

Lysyl-tRNA synthetase as a drug target in malaria and cryptosporidiosis

Juan A. Bueren-Calabuig, Andrei V. Pisliakov, David W. Gray, 2019, Proceedings of the National Academy of Sciences.

A suite of phenotypic assays to ensure pipeline diversity when prioritizing drug-like Cryptosporidium growth inhibitors

C. Huston, M. Love, C. McNamara, 2019, Nature Communications.

Spontaneous Selection of Cryptosporidium Drug Resistance in a Calf Model of Infection

D. Griggs, F. Buckner, C. Verlinde, 2021, Antimicrobial Agents and Chemotherapy.

Identification of a potent benzoxaborole drug candidate for treating cryptosporidiosis

J. Gut, C. Huston, J. Plattner, 2019, Nature Communications.

A suite of phenotypic assays to ensure pipeline diversity when prioritizing drug-like Cryptosporidium growth inhibitors

C. Huston, M. Love, C. McNamara, 2019, Nature Communications.

Knockdown of Five Genes Encoding Uncharacterized Proteins Inhibits Entamoeba histolytica Phagocytosis of Dead Host Cells

C. Huston, P. Miller, Adam Sateriale, 2016, Infection and Immunity.

Feed-Forward Regulation of Phagocytosis by Entamoeba histolytica

C. Huston, P. Miller, Liam Donnelly, 2012, Infection and Immunity.

, Peter by Entamoeba histolytica Feed-Forward Regulation of Phagocytosis

P. Miller, Liam Donnelly, Adam Sateriale, 2012 .

Entamoeba histolytica Cell Surface Calreticulin Binds Human C1q and Functions in Amebic Phagocytosis of Host Cells

C. Huston, P. Miller, J. Teixeira, 2012, Infection and Immunity.

Structure-Activity Relationship Studies of the Aryl Acetamide Triazolopyridazines against Cryptosporidium Reveals Remarkable Role of Fluorine.

D. Griggs, C. Huston, Edmund Oboh, 2023, Journal of medicinal chemistry.

Entamoeba histolytica Cell Surface Calreticulin Binds Human C1q and Functions in Amebic Phagocytosis of Host Cells

C. Huston, P. Miller, J. Teixeira, 2012, Infection and Immunity.

Identification of potent and orally efficacious phosphodiesterase inhibitors in sCryptosporidium parvum-infected immunocompromised mice

C. Huston, E. Stebbins, P. Miller, 2023, bioRxiv.