Guicheng Zhang

发表

The highly potent and selective dipeptidyl peptidase IV inhibitors bearing a thienopyrimidine scaffold effectively treat type 2 diabetes.

Hongjian Xu, R. Dai, Wenhui Hu, 2011, European journal of medicinal chemistry.

Rapid generation of a novel DPP-4 inhibitor with long-acting properties: SAR study and PK/PD evaluation.

Hongjian Xu, Wenhui Hu, Guifa Zhong, 2017, European journal of medicinal chemistry.

Determination of a novel dipeptidyl peptidase IV inhibitor in monkey plasma by HPLC-MS/MS and its application in a pharmacokinetics study.

R. Dai, Jifeng Deng, Guicheng Zhang, 2016, Journal of pharmaceutical and biomedical analysis.

Highly potent dipeptidyl peptidase IV inhibitors derived from Alogliptin through pharmacophore hybridization and lead optimization.

Hongjian Xu, Zheng-chao Tu, Wenhui Hu, 2013, European journal of medicinal chemistry.

Organocatalytic Enantioselective Aza‐Michael Reaction of Benzotriazole to β,β‐Disubstituted Nitroalkenes

Guicheng Zhang, Junling Zhao, Qinxin Lou, 2015 .

Design and synthesis of pinane oxime derivatives as novel anti-influenza agents.

Wenhui Hu, Guicheng Zhang, Jianghong Dong, 2020, Bioorganic chemistry.

A practical synthesis of trifluorophenyl R-amino acid: The key precursor for the new anti-diabetic drug sitagliptin

Guicheng Zhang, Hong-rui Song, Wenhui Hu, 2009 .

Discovery of potent dipeptidyl peptidase IV inhibitors through pharmacophore hybridization and hit-to-lead optimization.

Hongjian Xu, Zheng-chao Tu, Wenhui Hu, 2013, Bioorganic & medicinal chemistry.

Novel pyrrolopyrimidine analogues as potent dipeptidyl peptidase IV inhibitors based on pharmacokinetic property-driven optimization.

Hongjian Xu, Zheng-chao Tu, Wenhui Hu, 2012, European journal of medicinal chemistry.