S. Belanger

发表

Arylacetamide κ opioid receptor agonists with reduced cytochrome P450 2D6 inhibitory activity

R. Dolle, J. Cassel, R. Susnow, 2005 .

Further studies of tyrosine surrogates in opioid receptor peptide ligands.

T. Graczyk, R. Dolle, R. Dehaven, 2007, Bioorganic & medicinal chemistry letters.

Spirocyclic delta opioid receptor agonists for the treatment of pain: discovery of N,N-diethyl-3-hydroxy-4-(spiro[chromene-2,4'-piperidine]-4-yl) benzamide (ADL5747).

T. Graczyk, Michael Koblish, R. Dolle, 2009, Journal of medicinal chemistry.

Novel malonamide derivatives as potent κ opioid receptor agonists

T. Graczyk, Michael Koblish, R. Dolle, 2007 .

Azepinone as a conformational constraint in the design of κ-opioid receptor agonists

Michael Koblish, R. Dolle, J. Cassel, 2004 .

Novel phenylamino acetamide derivatives as potent and selective κ opioid receptor agonists

Michael Koblish, R. Dolle, J. Cassel, 2006 .

Novel phenylamino acetamide derivatives as potent and selective kappa opioid receptor agonists.

Michael Koblish, R. Dolle, J. Cassel, 2006, Bioorganic & medicinal chemistry letters.

(4-Carboxamido)phenylalanine is a surrogate for tyrosine in opioid receptor peptide ligands.

T. Graczyk, R. Dolle, J. Cassel, 2004, Bioorganic & medicinal chemistry letters.

Potent, orally bioavailable delta opioid receptor agonists for the treatment of pain: discovery of N,N-diethyl-4-(5-hydroxyspiro[chromene-2,4'-piperidine]-4-yl)benzamide (ADL5859).

T. Graczyk, Michael Koblish, R. Dolle, 2008, Journal of medicinal chemistry.

Novel trans-3,4-dimethyl-4-(3-hydroxyphenyl)piperidines as mu opioid receptor antagonists with improved opioid receptor selectivity profiles.

R. Dolle, J. Cassel, B. Le Bourdonnec, 2008, Bioorganic & medicinal chemistry letters.

Synthesis and structure-activity relationships of a new series of 2alpha-substituted trans-4,5-dimethyl-4-(3-hydroxyphenyl)piperidine as mu-selective opioid antagonists.

T. Graczyk, R. Dolle, B. Le Bourdonnec, 2006, Bioorganic & medicinal chemistry letters.

trans-3,4-dimethyl-4-(3-carboxamidophenyl)piperidines: a novel class of micro-selective opioid antagonists.

R. Dolle, J. Cassel, B. Le Bourdonnec, 2003, Bioorganic & medicinal chemistry letters.

Elucidation of the bioactive conformation of the N-substituted trans-3,4-dimethyl-4-(3-hydroxyphenyl)piperidine class of mu-opioid receptor antagonists.

T. Graczyk, T. Herbertz, R. Dolle, 2006, Journal of medicinal chemistry.

Potent and highly selective kappa opioid receptor agonists incorporating chroman- and 2,3-dihydrobenzofuran-based constraints.

T. Graczyk, Michael Koblish, R. Dolle, 2005, Bioorganic & medicinal chemistry letters.