L. Colwell

发表

Potent and selective proline derived dipeptidyl peptidase IV inhibitors.

N. Thornberry, B. Leiting, Sanjeev Kumar, 2004, Bioorganic & medicinal chemistry letters.

4-Amino cyclohexylglycine analogues as potent dipeptidyl peptidase IV inhibitors.

Aleksandr Petrov, N. Thornberry, B. Leiting, 2004, Bioorganic & medicinal chemistry letters.

Design, synthesis, and structure-activity relationship of podocarpic acid amides as liver X receptor agonists for potential treatment of atherosclerosis.

J. Menke, Neelam Sharma, Charlotte Burton, 2005, Bioorganic & medicinal chemistry letters.

Photodegradation of avermectin B1a thin films on glass

W. Feely, B. Arison, L. Colwell, 1991 .

Control of rat tail skin temperature regulation by estrogen receptor-beta selective ligand.

H. Wilkinson, G. Rodan, D. Towler, 2009, Maturitas.

Substituted oxazole benzenesulfonamides as potent human beta3 adrenergic receptor agonists.

C. Strader, D. Macintyre, M. Forrest, 2000, Bioorganic & medicinal chemistry letters.

Discovery of an orally bioavailable alkyl oxadiazole beta3 adrenergic receptor agonist.

R. Miller, C. Strader, D. Macintyre, 2000, Bioorganic & medicinal chemistry letters.

L-770,644: a potent and selective human beta3 adrenergic receptor agonist with improved oral bioavailability.

R. Miller, C. Strader, D. Macintyre, 1999, Bioorganic & medicinal chemistry letters.

Discovery of a potent, orally bioavailable beta(3) adrenergic receptor agonist, (R)-N-[4-[2-[[2-hydroxy-2-(3-pyridinyl)ethyl]amino]ethyl]phenyl]-4-[4 -[4-(trifluoromethyl)phenyl]thiazol-2-yl]benzenesulfonamide.

R. Miller, D. Macintyre, M. Forrest, 2000, Journal of medicinal chemistry.

Human beta3-adrenergic receptor agonists containing 1,2,3-triazole-substituted benzenesulfonamides.

D. Macintyre, M. Forrest, M. Fisher, 2000, Bioorganic & medicinal chemistry letters.

Estrogen receptor ligands. Part 10: Chromanes: old scaffolds for new SERAMs.

H. Wilkinson, D. Kimmel, L. Freedman, 2005, Bioorganic & medicinal chemistry letters.

Selective PPARgamma modulators with improved pharmacological profiles.

Margaret S. Wu, J. Berger, D. Moller, 2005, Bioorganic & medicinal chemistry letters.

Benzoyl 2-methyl indoles as selective PPARgamma modulators.

J. Berger, D. Moller, T. Doebber, 2005, Bioorganic & medicinal chemistry letters.

ENZYMATICSYNTHESIS AND IMMUNOSUPPRESSIVEACTIVITY OF NOVEL DESMETHYLATEDIMMUNOMYCINS(ASCOMYCINS)t

Ali, S., L. Colwell, 2006 .

Enzymatic synthesis and immunosuppressive activity of novel desmethylated immunomycins (ascomycins).

F. Dumont, B. Arison, L. Colwell, 1993, The Journal of antibiotics.

The preparation of zaragozic acid A analogues by directed biosynthesis.

R. Monaghan, R. White, J. Macconnell, 1994, The Journal of antibiotics.

Evaluation of endo- and exo-aryl-substitutions and central scaffold modifications on diphenyl substituted alkanes as 5-lipoxygenase activating protein inhibitors.

Jilly F. Evans, L. Chu, F. Ujjainwalla, 2012, Bioorganic & medicinal chemistry letters.

Nocathiacin analogs: Synthesis and antibacterial activity of novel water-soluble amides.

P. Meinke, J. Barrett, L. Colwell, 2009, Bioorganic & medicinal chemistry letters.

Structure-activity relationship of heterobase-modified 2'-C-methyl ribonucleosides as inhibitors of hepatitis C virus RNA replication.

P. D. Cook, J. Tomassini, M. Maccoss, 2004, Journal of medicinal chemistry.

Platensimycin is a selective FabF inhibitor with potent antibiotic properties

Jun Wang, Olga Genilloud, Sang Ho Lee, 2006, Nature.

A 7-Deaza-Adenosine Analog Is a Potent and Selective Inhibitor of Hepatitis C Virus Replication with Excellent Pharmacokinetic Properties

Giovanni Migliaccio, D. Hazuda, J. Tomassini, 2004, Antimicrobial Agents and Chemotherapy.

Potent, orally absorbed glucagon receptor antagonists.

M. Maccoss, C. Hacker, S. D. de Laszlo, 1999, Bioorganic & medicinal chemistry letters.

Triazolo-tetrahydrofluorenones as selective estrogen receptor beta agonists.

S. Nilsson, A. Thorsell, L. Colwell, 2006, Bioorganic & medicinal chemistry letters.

Characterization of Resistance to Non-obligate Chain-terminating Ribonucleoside Analogs That Inhibit Hepatitis C Virus Replication in Vitro*

D. Hazuda, R. Cortese, J. Tomassini, 2003, Journal of Biological Chemistry.

Estrogen receptor beta-subtype selective tetrahydrofluorenones: use of a fused pyrazole as a phenol bioisostere.

S. Nilsson, A. Thorsell, L. Colwell, 2006, Bioorganic & medicinal chemistry letters.

Synthesis and SAR of benzyl and phenoxymethylene oxadiazole benzenesulfonamides as selective beta3 adrenergic receptor agonist antiobesity agents.

C. Strader, D. Macintyre, M. Forrest, 2000, Bioorganic & medicinal chemistry letters.

Autooxidation of simvastatin

A. W. Douglas, R. Reamer, L. Colwell, 1993 .

3-Pyridylethanolamines: potent and selective human beta 3 adrenergic receptor agonists.

C. Strader, D. Macintyre, M. Forrest, 1998, Bioorganic & medicinal chemistry letters.

Benzoyl 2-methyl indoles as selective PPARγ modulators

Joel P. Berger, J. Berger, D. Moller, 2005 .

Highly functionalized 7-azaindoles as selective PPAR gamma modulators.

Margaret S. Wu, J. Berger, T. Doebber, 2008, Bioorganic & medicinal chemistry letters.

Selective PPARγ modulators with improved pharmacological profiles

Margaret S. Wu, J. Berger, D. Moller, 2005 .

Estrogen receptor ligands. Part 4: The SAR of the syn-dihydrobenzoxathiin SERAMs.

J. Schaeffer, L. Colwell, S. Rohrer, 2004, Bioorganic & medicinal chemistry letters.

Human beta3 adrenergic receptor agonists containing imidazolidinone and imidazolone benzenesulfonamides.

C. Strader, D. Macintyre, M. Forrest, 1999, Bioorganic & medicinal chemistry letters.

In Vivo Efficacy of Relebactam (MK-7655) in Combination with Imipenem-Cilastatin in Murine Infection Models

M. Motyl, Jin Wu, Andrew M. Galgoci, 2018, Antimicrobial Agents and Chemotherapy.

Substituted piperazines as novel dipeptidyl peptidase IV inhibitors.

N. Thornberry, B. Leiting, Huaibing He, 2004, Bioorganic & medicinal chemistry letters.

Discovery of (2R)-2-(3-{3-[(4-Methoxyphenyl)carbonyl]-2-methyl-6-(trifluoromethoxy)-1H-indol-1-yl}phenoxy)butanoic acid (MK-0533): a novel selective peroxisome proliferator-activated receptor gamma modulator for the treatment of type 2 diabetes mellitus with a reduced potential to increase plasma an

Margaret S. Wu, Harold B Wood, Yejun Tan, 2009, Journal of medicinal chemistry.

HIV-1 protease inhibitory activity of L-694,746, a novel metabolite of L-689,502.

P. Darke, G. Garrity, B. Arison, 1991, Biochemical and biophysical research communications.

Potent and selective proline derived dipeptidyl peptidase IV inhibitors.

N. Thornberry, B. Leiting, Sanjeev Kumar, 2004, Bioorganic & Medicinal Chemistry Letters.