C. Seyler

发表

Anesthetic drug midazolam inhibits cardiac human ether-à-go-go-related gene channels: mode of action

H. Katus, Dierk Thomas, E. Zitron, 2015, Drug design, development and therapy.

Acute and subacute effects of the selective serotonin–noradrenaline reuptake inhibitor duloxetine on cardiac hERG channels

E. Zitron, E. Scholz, H. Katus, 2013, Naunyn-Schmiedeberg's Archives of Pharmacology.

Carvedilol targets human K2P3.1 (TASK1) K+ leak channels

H. Katus, Ann-Kathrin Rahm, E. Ficker, 2011, British journal of pharmacology.

Central role of PKCα in isoenzyme-selective regulation of cardiac transient outward current Ito and Kv4.3 channels.

M. Völkers, H. Katus, Dierk Thomas, 2011, Journal of molecular and cellular cardiology.

Inhibition of inwardly rectifying Kir2.x channels by the novel anti-cancer agent gambogic acid depends on both pore block and PIP2 interference

H. Katus, Dierk Thomas, E. Zitron, 2017, Naunyn-Schmiedeberg's Archives of Pharmacology.

Data privacy management and data quality monitoring in the German Centre for Cardiovascular Research's multicentre TranslatiOnal Registry for CardiomyopatHies (DZHK‐TORCH)

Hugo A. Katus, Wolfgang Hoffmann, Thomas Bahls, 2017, ESC heart failure.

TranslatiOnal Registry for CardiomyopatHies (TORCH) – rationale and first results

W. Hoffmann, H. Katus, B. Meder, 2017, ESC heart failure.

Inhibition of cardiac Kir2.1-2.3 channels by beta3 adrenoreceptor antagonist SR 59230A.

H. Katus, Dierk Thomas, E. Zitron, 2012, Biochemical and biophysical research communications.

Selective noradrenaline reuptake inhibitor atomoxetine directly blocks hERG currents

W. Rottbauer, G. Seemann, H. Katus, 2009, British journal of pharmacology.

Augmentation of myocardial If dysregulates calcium homeostasis and causes adverse cardiac remodeling

A. Draguhn, C. Bruehl, R. Fink, 2019, Nature Communications.

Therapeutic targeting of two-pore-domain potassium (K(2P)) channels in the cardiovascular system.

H. Katus, Dierk Thomas, C. Schmidt, 2016, Clinical science.

Modulation of K2P2.1 and K2P10.1 K+ channel sensitivity to carvedilol by alternative mRNA translation initiation

H. Katus, P. Schweizer, D. Thomas, 2014, British journal of pharmacology.

Inhibition of cardiac two-pore-domain K+ (K2P) channels by the antiarrhythmic drug vernakalant--comparison with flecainide.

H. Katus, Dierk Thomas, P. Schweizer, 2014, European journal of pharmacology.

Vernakalant activates human cardiac K(2P)17.1 background K(+) channels.

H. Katus, Dierk Thomas, E. Zitron, 2014, Biochemical and biophysical research communications.

Inhibition of cardiac Kv1.5 potassium current by the anesthetic midazolam: mode of action

H. Katus, Dierk Thomas, E. Zitron, 2014, Drug design, development and therapy.

The symptom complex of familial sinus node dysfunction and myocardial noncompaction is associated with mutations in the HCN4 channel.

A. Draguhn, C. Bruehl, J. Haas, 2014, Journal of the American College of Cardiology.

Dual Mechanism for Inhibition of Inwardly Rectifying Kir2.x Channels by Quinidine Involving Direct Pore Block and PIP2-interference

H. Katus, Dierk Thomas, E. Zitron, 2017, The Journal of Pharmacology and Experimental Therapeutics.

Inhibition of cardiac Kv1.5 and Kv4.3 potassium channels by the class Ia anti-arrhythmic ajmaline: mode of action

H. Katus, E. Zitron, E. Scholz, 2013, Naunyn-Schmiedeberg's Archives of Pharmacology.

Provocation of an autoimmune response to cardiac voltage-gated sodium channel NaV1.5 induces cardiac conduction defects in rats.

M. Karck, H. Katus, E. Giannitsis, 2013, Journal of the American College of Cardiology.

Isoenzyme-specific regulation of cardiac Kv1.5/Kvβ1.2 ion channel complex by protein kinase C: central role of PKCβII

H. Katus, Dierk Thomas, E. Zitron, 2014, Naunyn-Schmiedeberg's Archives of Pharmacology.

Anti-KCNQ1 K⁺ channel autoantibodies increase IKs current and are associated with QT interval shortening in dilated cardiomyopathy.

H. Katus, Dierk Thomas, C. Schmidt, 2013, Cardiovascular research.

Class III antiarrhythmic drug dronedarone inhibits cardiac inwardly rectifying Kir2.1 channels through binding at residue E224

H. Katus, Dierk Thomas, E. Zitron, 2014, Naunyn-Schmiedeberg's Archives of Pharmacology.

I Ks current and are associated with QT interval shortening in dilated cardiomyopathy

H. Katus, Dierk Thomas, C. Schmidt, 2013 .

Inhibition of cardiac Kv1.5 and Kv4.3 potassium channels by the class Ia anti-arrhythmic ajmaline: mode of action

H. Katus, E. Zitron, E. Scholz, 2013, Naunyn-Schmiedeberg's Archives of Pharmacology.

miR-19b Regulates Ventricular Action Potential Duration in Zebrafish

A. Benz, H. Katus, E. Zitron, 2016, Scientific Reports.

TASK1 (K2P3.1) K+ channel inhibition by endothelin‐1 is mediated through Rho kinase‐dependent phosphorylation

J. Gierten, E. Zitron, H. Katus, 2012, British journal of pharmacology.

Inhibition of Histone Deacetylases Induces K+ Channel Remodeling and Action Potential Prolongation in HL-1 Atrial Cardiomyocytes

H. Katus, Dierk Thomas, P. Lugenbiel, 2018, Cellular Physiology and Biochemistry.

Efficacy, High Procedural Safety And Rapid Optimization Of Cryoballoon Atrial Fibrillation Ablation In The Hands Of A New Operator.

H. Katus, Dierk Thomas, P. Lugenbiel, 2016, Journal of atrial fibrillation.

TREK-1 (K2P2.1) K+ channels are suppressed in patients with atrial fibrillation and heart failure and provide therapeutic targets for rhythm control

C. Bruehl, M. Karck, H. Katus, 2016, Basic Research in Cardiology.

Acute and subacute effects of the selective serotonin–noradrenaline reuptake inhibitor duloxetine on cardiac hERG channels

E. Zitron, E. Scholz, H. Katus, 2013, Naunyn-Schmiedeberg's Archives of Pharmacology.

Biophysical properties of zebrafish ether-à-go-go related gene potassium channels.

Daniel Scherer, Hugo A Katus, Edgar Zitron, 2009, Biochemical and biophysical research communications.

Subtype-specific differentiation of cardiac pacemaker cell clusters from human induced pluripotent stem cells

J. Utikal, A. Draguhn, H. Katus, 2017, Stem Cell Research & Therapy.

Genetic suppression of atrial fibrillation using a dominant-negative ether-a-go-go-related gene mutant.

H. Katus, Dierk Thomas, A. Bauer, 2012, Heart rhythm.

Role of plasma membrane-associated AKAPs for the regulation of cardiac IK1 current by protein kinase A

H. Katus, J. Backs, Dierk Thomas, 2017, Naunyn-Schmiedeberg's Archives of Pharmacology.

Inhibition of Cardiac Kir Current (IK1) by Protein Kinase C Critically Depends on PKCβ and Kir2.2

M. Andrassy, M. Völkers, H. Katus, 2016, PloS one.

Subtype-specific differentiation of cardiac pacemaker cell clusters from human induced pluripotent stem cells

J. Utikal, A. Draguhn, H. Katus, 2017, Stem Cell Research & Therapy.

Retinal Arterio-Venule-Ratio (AVR) in the cardiovascular risk management of hypertension

Hugo A. Katus, Daniel Scherer, Eberhard P. Scholz, 2013 .

Anti-KCNQ1 K⁺ channel autoantibodies increase IKs current and are associated with QT interval shortening in dilated cardiomyopathy.

H. Katus, Dierk Thomas, C. Schmidt, 2013, Cardiovascular research.

Isoenzyme-specific regulation of cardiac Kv1.5/Kvβ1.2 ion channel complex by protein kinase C: central role of PKCβII

H. Katus, Dierk Thomas, E. Zitron, 2014, Naunyn-Schmiedeberg's Archives of Pharmacology.

Title: Dual Mechanism for Inhibition of Inwardly Rectifying Kir2.x Channels by Quinidine Involving Direct Pore Block and Pip 2 -interference Jpet #238287 4 Block and an Impaired Channel Stabilization via Interference with Pip 2

Germany, H. Katus, Dierk Thomas, 2022 .