Y. Nagisa

发表

Synthesis, structure-activity relationship, and pharmacological studies of novel melanin-concentrating hormone receptor 1 antagonists 3-aminomethylquinolines: reducing human ether-a-go-go-related gene (hERG) associated liabilities.

J. Kunitomo, Masaharu Nakayama, Koki Kato, 2012, Journal of medicinal chemistry.

Melanin-concentrating hormone receptor 1 antagonists. Synthesis and structure-activity relationships of novel 3-(aminomethyl)quinolines.

Koki Kato, Y. Nakano, Toshio Tanaka, 2012, Journal of medicinal chemistry.

Amine-free melanin-concentrating hormone receptor 1 antagonists: Novel 1-(1H-benzimidazol-6-yl)pyridin-2(1H)-one derivatives and design to avoid CYP3A4 time-dependent inhibition.

Masaharu Nakayama, S. Okuda, Masashi Takahashi, 2016, Bioorganic & medicinal chemistry.

Changes in glycated haemoglobin levels in diabetic rats measured with an automatic affinity HPLC

Koki Kato, Kaoru Watanabe, Y. Nagisa, 2003, Clinical and experimental pharmacology & physiology.

A novel and selective melanin‐concentrating hormone receptor 1 antagonist ameliorates obesity and hepatic steatosis in diet‐induced obese rodent models

Masaharu Nakayama, A. Ando, S. Okuda, 2017, European journal of pharmacology.

Amine-free melanin-concentrating hormone receptor 1 antagonists: Novel non-basic 1-(2H-indazole-5-yl)pyridin-2(1H)-one derivatives and mitigation of mutagenicity in Ames test.

Masaharu Nakayama, S. Okuda, Masashi Takahashi, 2016, Bioorganic & medicinal chemistry.

A Selective Bombesin Receptor Subtype 3 Agonist Promotes Weight Loss in Male Diet-Induced–Obese Rats With Circadian Rhythm Change

M. Maruyama, Y. Habata, S. Okuda, 2017, Endocrinology.

Bombesin receptor subtype‐3‐expressing neurons regulate energy homeostasis through a novel neuronal pathway in the hypothalamus

M. Maruyama, Y. Habata, N. Amano, 2017, Brain and behavior.

Melanin-Concentrating Hormone Receptor 1 Antagonists Lacking an Aliphatic Amine: Synthesis and Structure-Activity Relationships of Novel 1-(Imidazo[1,2-a]pyridin-6-yl)pyridin-2(1H)-one Derivatives.

Masaharu Nakayama, Masashi Takahashi, H. Hirabayashi, 2016, Journal of medicinal chemistry.

Melanin-concentrating hormone receptor 1 antagonists: synthesis, structure-activity relationship, docking studies, and biological evaluation of 2,3,4,5-tetrahydro-1H-3-benzazepine derivatives.

Koki Kato, Y. Nakano, M. Tawada, 2011, Bioorganic & medicinal chemistry.

Discovery, synthesis, and structure-activity relationship of 6-aminomethyl-7,8-dihydronaphthalenes as human melanin-concentrating hormone receptor 1 antagonists.

Koki Kato, Y. Nakano, S. Endo, 2011, Bioorganic & Medicinal Chemistry.

Beneficial effects of TDN-345, a novel Ca2+ antagonist, on ischemic brain injury and cerebral glucose metabolism in experimental animal models with cerebrovascular lesions

Y. Nagai, Y. Nagisa, T. Nakayama, 1997, Brain Research.

The angiotensin II receptor antagonist candesartan cilexetil (TCV-116) ameliorates retinal disorders in rats

Y. Nagisa, S. Nakagawa, A. Shintani, 2001, Diabetologia.

脳卒中易発症系高血圧自然発症ラット(SHRSP)における脳血管障害に伴う神経症状および組織学的変化に対するイデベノンと塩酸マニジピンの併用効果

A. Nagaoka, H. Kandori, Y. Nagisa, 1995 .

Melanin-Concentrating Hormone Receptor 1 Antagonists Lacking an Aliphatic Amine: Synthesis and Structure-Activity Relationships of Novel 1-(Imidazo[1,2-a]pyridin-6-yl)pyridin-2(1H)-one Derivatives.

Masaharu Nakayama, Masashi Takahashi, H. Hirabayashi, 2016, Journal of Medicinal Chemistry.

Melanin-concentrating hormone receptor 1 antagonists: synthesis, structure-activity relationship, docking studies, and biological evaluation of 2,3,4,5-tetrahydro-1H-3-benzazepine derivatives.

Koki Kato, Y. Nakano, M. Tawada, 2011, Bioorganic & Medicinal Chemistry.

[Beneficial effects of the combination of idebenone and manidipine 2HCl on neurological deficits and histological changes following cerebrovascular lesions in stroke-prone spontaneously hypertensive rats].

Y. Nagisa, K. Hamajo, T. Imamoto, 1995, Nihon yakurigaku zasshi. Folia pharmacologica Japonica.