C. B. Jeppesen

发表

Ureas with histamine H3-antagonist receptor activity--a new scaffold discovered by lead-hopping from cinnamic acid amides.

K. Rimvall, J. Lau, C. B. Jeppesen, 2006, Bioorganic & medicinal chemistry letters.

Structure-based Design of a Low Molecular Weight, Nonphosphorus, Nonpeptide, and Highly Selective Inhibitor of Protein-tyrosine Phosphatase 1B*

Ole Hvilsted Olsen, Sven Branner, O. Olsen, 2000, The Journal of Biological Chemistry.

Small-molecule agonists for the glucagon-like peptide 1 receptor

Jeppe Sturis, Jarek Kostrowicki, Carsten Behrens, 2007, Proceedings of the National Academy of Sciences.

Differential structural properties of GLP-1 and exendin-4 determine their relative affinity for the GLP-1 receptor N-terminal extracellular domain.

R. Rudolph, S. M. Knudsen, K. Madsen, 2007, Biochemistry.

Demonstration of a common DPhe7 to DNal(2’)7 peptide ligand antagonist switch for the melanocortin-3 and melanocortin-4 receptors identifies systematic mischaracterization of the pharmacological properties of melanocortin peptides

P. Grieco, R. Cone, K. Conde-Frieboes, 2022, bioRxiv.

Demonstration of a Common DPhe7 to DNal(2′)7 Peptide Ligand Antagonist Switch for Melanocortin-3 and Melanocortin-4 Receptors Identifies the Systematic Mischaracterization of the Pharmacological Properties of Melanocortin Peptides

P. Grieco, R. Cone, K. Conde-Frieboes, 2022, Journal of medicinal chemistry.

Recombinant Adiponectin Does Not Lower Plasma Glucose in Animal Models of Type 2 Diabetes

T. N. Krogh, J. Brandt, B. Rolin, 2012, PloS one.

Changes in Glucose and Fat Metabolism in Response to the Administration of a Hepato-Preferential Insulin Analog

D. Edgerton, A. Cherrington, M. Scott, 2014, Diabetes.

Open flow microperfusion: pharmacokinetics of human insulin and insulin detemir in the interstitial fluid of subcutaneous adipose tissue

T. Pieber, F. Sinner, E. Nishimura, 2015, Diabetes, obesity & metabolism.

The effect of fatty diacid acylation of human PYY3-36 on Y2 receptor potency and half-life in minipigs

Jørgen Olsen, Rasmus Jorgensen, S. Østergaard, 2021, Scientific Reports.

Elucidating the Mechanism of Absorption of Fast-Acting Insulin Aspart: The Role of Niacinamide

J. Sturis, H. H. Refsgaard, U. Ribel, 2019, Pharmaceutical Research.

Human glucagon receptor antagonists with thiazole cores. A novel series with superior pharmacokinetic properties.

C. Behrens, L. B. Knudsen, E. Nishimura, 2009, Journal of medicinal chemistry.

Novel glucagon receptor antagonists with improved selectivity over the glucose-dependent insulinotropic polypeptide receptor.

C. Behrens, L. B. Knudsen, E. Nishimura, 2008, Journal of medicinal chemistry.

Identification and synthesis of a novel selective partial PPARdelta agonist with full efficacy on lipid metabolism in vitro and in vivo.

M. Havranek, J. Fleckner, J. Daugaard, 2007, Journal of medicinal chemistry.

Antagonistic targeting of the histamine H3 receptor decreases caloric intake in higher mammalian species.

S. Hastrup, B. Hansen, K. Rimvall, 2007, Biochemical pharmacology.

Structure-Based Design of Protein Tyrosine Phosphatase Inhibitors

L. Iversen, H. Andersen, C. B. Jeppesen, 2005 .

Glycosylation of an N-terminal extension prolongs the half-life and increases the in vivo activity of follicle stimulating hormone.

B. van den Hazel, T. Halkier, K. V. Andersen, 2003, The Journal of clinical endocrinology and metabolism.

Design of a partial PPARδ agonist

M. Havranek, I. Pettersson, P. Sauerberg, 2007 .

Novel selective PPARdelta agonists: optimization of activity by modification of alkynylallylic moiety.

M. Havranek, I. Pettersson, P. Kratina, 2007, Bioorganic & medicinal chemistry letters.

Molecular Engineering of Insulin Icodec, the First Acylated Insulin Analog for Once-Weekly Administration in Humans.

H. H. Refsgaard, T. Porsgaard, E. Nishimura, 2021, Journal of medicinal chemistry.

2-(Oxalylamino)-Benzoic Acid Is a General, Competitive Inhibitor of Protein-tyrosine Phosphatases*

L. Iversen, H. Andersen, C. B. Jeppesen, 2000, The Journal of Biological Chemistry.

Insulin binding to the analytical antibody sandwich pair OXI‐005 and HUI‐018: Epitope mapping and binding properties

E. Johansson, Xiaoai Wu, Bingke Yu, 2020, Protein science : a publication of the Protein Society.

Comparison of a luminescent oxygen channeling immunoassay and an ELISA for detecting insulin aspart in human serum.

Ole Skyggebjerg, S. B. Petersen, O. Skyggebjerg, 2010, Journal of pharmaceutical and biomedical analysis.

Engineering of Orally Available, Ultralong-Acting Insulin Analogues: Discovery of OI338 and OI320.

H. H. Refsgaard, M. Münzel, L. Hovgaard, 2020, Journal of medicinal chemistry.

Development of Cagrilintide, a Long-Acting Amylin Analogue.

S. Fulle, T. Kruse, J. L. Hansen, 2021, Journal of medicinal chemistry.

In vitro prediction of in vivo pseudo-allergenic response via MRGPRX2

B. Wulff, K. Conde-Frieboes, N. P. Knudsen, 2021, Journal of immunotoxicology.

Synthesis of 2‐amino‐4h‐thiazolo[5,4‐b]indole and characterization of its colored conversion products with protein tyrosine phosphatase inhibitory activity

C. Olsen, H. Andersen, N. Møller, 2001 .

Inhibitors of Protein Kinases and Protein Phosphates Contributors

L. Meijer, D. Fabbro, M. Yacoub, 2005 .