M. Wallace

发表

Use of Dibutyl[14C]formamide as a Formylating Reagent in the Vilsmeier–Haack Reaction and Synthesis of a 14C‐Labeled Novel Phosphodiesterase‐4 (PDE‐4) Inhibitor

D. Dean, D. Melillo, M. Braun, 2005 .

Activation of phospholipase C in rabbit brain membranes by carbachol in the presence of GTP gamma S; effects of biological detergents.

M. Wallace, H. R. Carter, J. Fain, 1990, Biochimica et biophysica acta.

Metabolites of caspofungin acetate, a potent antifungal agent, in human plasma and urine.

T. Baillie, X. Xu, D. Dean, 2000, Drug metabolism and disposition: the biological fate of chemicals.

Regulation of Ca2+-Mg2+-ATPase activity in hepatocyte plasma membranes by vasopressin and phenylephrine.

S. H. Lin, M. Wallace, J. Fain, 1983, Endocrinology.

A Small Molecule α4β1/α4β7 Antagonist Differentiates between the Low-Affinity States of α4β1 and α4β7: Characterization of Divalent Cation Dependence

S. D. de Laszlo, P. Detmers, C. Raab, 2003, Journal of Pharmacology and Experimental Therapeutics.

IN VITRO METABOLISM OF MK-0767 [(±)-5-[(2,4-DIOXOTHIAZOLIDIN-5-YL)METHYL]-2-METHOXY-N-[[(4-TRIFLUOROMETHYL) PHENYL]METHYL]BENZAMIDE], A PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR α/γ AGONIST. I. ROLE OF CYTOCHROME P450, METHYLTRANSFERASES, FLAVIN MONOOXYGENASES, AND ESTERASES

David Q. Liu, D. Dean, C. Hop, 2004, Drug Metabolism And Disposition.

Chemoselective methionine bioconjugation: site-selective fluorine-18 labeling of proteins and peptides.

A. Allentoff, Richard Y.-C. Huang, D. Donnelly, 2020, Bioconjugate chemistry.

Adnectin–drug conjugates for Glypican-3-specific delivery of a cytotoxic payload to tumors

Martin C. Wright, J. Bryson, V. Lafont, 2018, Protein engineering, design & selection : PEDS.

Metabolic effects of β, α1, and α2 adrenoceptor activation on brown adipocytes isolated from the perirenal adipose tissue of fetal lambs

M. Wallace, J. Fain, I. Mills, 1984 .

Alpha 1-adrenergic stimulation of phosphatidylinositol turnover and respiration of brown fat cells.

N. Mohell, M. Wallace, J. Fain, 1984, Molecular pharmacology.

Efficient utilization of [14C]carbon dioxide as a phosgene equivalent for labeled synthesis

D. Dean, D. Melillo, M. Wallace, 1997 .

Relationship Between Vasopressin Activation of Rat Hepatocyte Glycogen Phosphorylase, Inhibition of \(C{{a}^{{{{2}^{ + }}}}} - M{{g}^{{{{2}^{ + }}}}}\) and Phosphoinositide Breakdown

Sue-Hwa Lin, M. Wallace, J. Fain, 1985 .

The synthesis of carbon-14 labeled pravastatin

D. Dean, D. Melillo, R. F. White, 1993 .

Concerted CMP‐Dependent [3H]Inositol Labeling of Phosphoinositides and Agonist Activation of Phospholipase C in Rat Brain Cortical Membranes

E. Claro, M. Wallace, J. Fain, 1992, Journal of neurochemistry.

IN VITRO AND IN VIVO METABOLISM OF A POTENT AND SELECTIVE INTEGRIN (cid:1) v (cid:2) 3 ANTAGONIST IN RATS, DOGS, AND MONKEYS

J. Yergey, R. Subramanian, M. Braun, 2004 .

A novel radioligand for glycine transporter 1: characterization and use in autoradiographic and in vivo brain occupancy studies.

C. Lindsley, J. O'brien, M. Wallace, 2008, Nuclear medicine and biology.

Guanosine 5'-O-thiotriphosphate stimulates phospholipase C activity in plasma membranes of rat hepatocytes.

M. Wallace, J. Fain, 1985, The Journal of biological chemistry.

Pharmacological characterization and radioligand binding properties of a high-affinity, nonpeptide, bradykinin B1 receptor antagonist.

M. Bock, R. Freidinger, R. Chang, 2004, European journal of pharmacology.

Altered phosphoinositide-specific phospholipase C and adenylyl cyclase in brain cortical membranes of cats with GM1 and GM2 gangliosidosis.

H. J. Baker, T. Patel, E. Claro, 1991, Brain research. Molecular brain research.

Pharmacokinetics and disposition of the oxytocin receptor antagonist L-368,899 in rats and dogs.

R. Miller, W. Feeney, M. Wallace, 1997, Drug metabolism and disposition: the biological fate of chemicals.

Norepinephrine‐induced loss of phosphatidylinositol from isolated rat liver plasma membrane

J. Poggioli, M. Wallace, F. Giraud, 1983, FEBS letters.

Analysis of hormone-induced changes of phosphoinositide metabolism in rat liver.

M. Wallace, J. Fain, 1985, Methods in enzymology.

Effects of Alzheimer's disease-related beta amyloid protein fragments on enzymes metabolizing phosphoinositides in brain.

M. Wallace, 1994, Biochimica et biophysica acta.

Transmembrane signaling through phospholipase C in human cortical membranes

E. Claro, M. Wallace, 1993, Neurochemical Research.

The synthesis of HIV reverse transcriptase inhibitors [14C]L‐697,661, [14C]L‐697,639, [14C]L‐702,007

D. Dean, D. Melillo, M. Wallace, 1996 .

Highly Diastereoselective Alkylation of Chiral Amide Enolates: New Routes to Hydroxyethylene Dipeptide Isostere Inhibitors of HIV-1 Protease.

J. Vacca, R. Volante, R. Reamer, 1992 .

Highly diastereoselective alkylations of chiral amide enolates: new routes to hydroxyethylene dipeptide isostere inhibitors of HIV-1 protease

J. Vacca, R. Volante, R. Reamer, 1992 .

Silicon-directed Nazarov cyclizations. 8. Stereoelectronic control of torquoselectivity

S. Denmark, C. Walker, M. Wallace, 1990 .

Synthesis of an adenine N-3 substituted CBI adduct by alkylation of adenine with a 1-iodomethylindoline seco-CBI precursor

A. Allentoff, M. Wallace, S. Bonacorsi, 2018, Tetrahedron.

Synthesis of [35S]aryl sulfonyl chlorides from [35S]elemental sulfur

C. Raab, D. Dean, D. Melillo, 2005 .

Direct Carbon Isotope Exchange through Decarboxylative Carboxylation.

A. Allentoff, Cian Kingston, P. Baran, 2018, Journal of the American Chemical Society.

[14C]Dimethyltitanocene and [14C]Methyl(methyltrimethylsilyl) titanocene–Reagents for the [14C]olefination of carbonyl compounds: synthesis of [14C]Aprepitant

D. Dean, D. Melillo, M. Wallace, 2009 .

Conditioned media from cultured cystic fibrosis fibroblasts inhibits Na/K ATPase activity.

A. von Euler, M. Wallace, 1985, Life sciences.

Ivermectin and nodulisporic acid receptors in Drosophila melanogaster contain both gamma-aminobutyric acid-gated Rdl and glutamate-gated GluCl alpha chloride channel subunits.

D. Cully, D. Dean, V. Warren, 2002, Biochemistry.

Modulation of the phospholipase C activity in rat brain cortical membranes by simultaneous activation of distinct monoaminergic and cholinergic muscarinic receptors.

J. Sallés, M. Wallace, J. Fain, 1993, Brain research. Molecular brain research.

IN VITRO AND IN VIVO METABOLISM OF A POTENT AND SELECTIVE INTEGRIN v 3 ANTAGONIST IN RATS , DOGS , AND MONKEYS

J. Yergey, R. Subramanian, M. Braun, 2004 .

Carbachol in the presence of guanosine 5'-O-(3-thiotriphosphate) stimulates the breakdown of exogenous phosphatidylinositol 4,5-bisphosphate, phosphatidylinositol 4-phosphate, and phosphatidylinositol by rat brain membranes.

E. Claro, M. Wallace, J. Fain, 1989, The Journal of biological chemistry.

Evidence for involvement of guanine nucleotide‐binding regulatory proteins in the activation of phospholipases by hormones

R. Wojcikiewicz, M. Wallace, J. Fain, 1988, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Discovery of Branebrutinib (BMS-986195): A Strategy for Identifying a Highly Potent and Selective Covalent Inhibitor Providing Rapid in Vivo Inactivation of Bruton's Tyrosine Kinase (BTK).

Michael A. Galella, K. McIntyre, J. Macor, 2019, Journal of medicinal chemistry.

Purification and characterization of PLC-beta m, a muscarinic cholinergic regulated phospholipase C from rabbit brain membrane.

M. Wallace, H. R. Carter, J. Fain, 1990, Biochimica et biophysica acta.

Applications of LC‐ARC™ stop‐flow radiochemical detection

D. Melillo, Steven J. Staskiewicz, J. Ho, 2007 .

Development of an efficient and selective radioligand for bradykinin B1 receptor occupancy studies.

M. Bock, R. Freidinger, R. Chang, 2004, Bioorganic & Medicinal Chemistry Letters.

Identification and characterization of a selective radioligand for melanin-concentrating hormone 1-receptor (MCH1R).

H. Iwaasa, H. Matsushita, D. Dean, 2009, Bioorganic & medicinal chemistry letters.

Dual effect of fluoride on phosphoinositide metabolism in rat brain cortex. Stimulation of phospholipase C and inhibition of polyphosphoinositide synthesis.

E. Claro, M. Wallace, J. Fain, 1990, Biochemical Journal.

Phosphoinositide-specific phospholipase C activation in brain cortical membranes.

E. Claro, M. Wallace, H. R. Carter, 1991, Methods in enzymology.

Differential effects of alkylating agents on the multiple muscarinic receptor subtypes linked to activation of phospholipase C by carbachol in rat brain cortical membranes.

J. Sallés, M. Wallace, J. Fain, 1993, The Journal of pharmacology and experimental therapeutics.

Alpha‐Adrenergic Stimulation of Phosphatidylinositol Synthesis in Human Platelets as an Alpha‐2 Effect Secondary to Platelet Aggregation

K. Agarwal, M. Wallace, J. Fain, 1982, Journal of cellular biochemistry.

Effects of the wasp venom peptide, mastoparan, on a phosphoinositide-specific phospholipase C purified from rabbit brain membranes.

M. Wallace, H. R. Carter, 1989, Biochimica et biophysica acta.

A novel role for dopamine: inhibition of muscarinic cholinergic-stimulated phosphoinositide hydrolysis in rat brain cortical membranes

E. Claro, M. Wallace, 1990, Neuroscience Letters.

Guanine nucleotide and pyrophosphate activate exogenous phosphatidylinositol 4,5-bisphosphate hydrolysis in rat liver plasma membranes.

D. Bojanic, R. Wojcikiewicz, M. Wallace, 1987, Biochemical and biophysical research communications.

A small molecule alpha4beta1/alpha4beta7 antagonist differentiates between the low-affinity states of alpha4beta1 and alpha4beta7: characterization of divalent cation dependence.

S. D. de Laszlo, P. Detmers, C. Raab, 2003, The Journal of pharmacology and experimental therapeutics.

EVALUATION OF MICRODOSING STRATEGIES FOR STUDIES IN PRECLINICAL DRUG DEVELOPMENT: DEMONSTRATION OF LINEAR PHARMACOKINETICS IN DOGS OF A NUCLEOSIDE ANALOG OVER A 50-FOLD DOSE RANGE

M. P. Baker, T. Baillie, J. Vogel, 2004, Drug Metabolism and Disposition.

Absorption, Metabolism, and Excretion of [14C]MK-0767 (2-Methoxy-5-(2,4-dioxo-5-thiazolidinyl)-N-[[4-(trifluoromethyl)phenyl] methyl]benzamide) in Humans

D. Dean, K. Lasseter, R. Franklin, 2006, Drug Metabolism and Disposition.

Mechanistic studies on the metabolic scission of thiazolidinedione derivatives to acyclic thiols.

T. Baillie, R. Franklin, M. Wallace, 2005, Chemical research in toxicology.

III. Hormonal regulation of phosphatidylinositol breakdown

Sue-Hwa Lin, M. Wallace, J. Fain, 1983 .

Direct stimulation of phosphatidylinositol degradation by addition of vasopressin to purified rat liver plasma membranes.

P. Randazzo, M. Wallace, J. Fain, 1982, Endocrinology.

[6] - Regulation of Phosphoinositide Metabolism in Membranes Prepared from Human Brain Cortex

M. Wallace, 1993 .

Hormonal Regulation of Phosphoinositide Metabolism in Rat Hepatocytes

Sue-Hwa Lin, M. Wallace, J. Fain, 1985 .

In vitro and in vivo metabolism of a potent and selective integrin alpha v beta 3 antagonist in rats, dogs, and monkeys.

J. Yergey, R. Subramanian, M. Braun, 2004, Drug metabolism and disposition: the biological fate of chemicals.

Comparison of serotoninergic to muscarinic cholinergic stimulation of phosphoinositide-specific phospholipase C in rat brain cortical membranes.

E. Claro, M. Wallace, 1990, The Journal of pharmacology and experimental therapeutics.

Synergistic activation of rat hepatocyte glycogen phosphorylase by A23187 and phorbol ester.

M. Wallace, J. Fain, I. Litosch, 1984, Biochemical and biophysical research communications.