S. Poulsen

发表

Natural products that inhibit carbonic anhydrase.

Rohan A. Davis, S. Poulsen, R. Davis, 2014, Sub-cellular biochemistry.

Design, synthesis, and biological evaluation of novel carbohydrate-based sulfamates as carbonic anhydrase inhibitors.

C. Supuran, A. Innocenti, D. Vullo, 2011, Journal of medicinal chemistry.

Sulfonamide linked neoglycoconjugates--a new class of inhibitors for cancer-associated carbonic anhydrases.

C. Supuran, A. Innocenti, D. Vullo, 2010, Journal of medicinal chemistry.

Carbonic anhydrase inhibitors developed through 'click tailing'.

C. Supuran, Marie Lopez, S. Poulsen, 2010, Current pharmaceutical design.

Promiscuity of carbonic anhydrase II. Unexpected ester hydrolysis of carbohydrate-based sulfamate inhibitors.

C. Supuran, A. Innocenti, Conan K. Wang, 2011, Journal of the American Chemical Society.

Fragment Screening by Native State Mass Spectrometry

S. Poulsen, 2014 .

Native State Mass Spectrometry, Surface Plasmon Resonance, and X-ray Crystallography Correlate Strongly as a Fragment Screening Combination.

T. Peat, B. Ren, O. Dolezal, 2016, Journal of medicinal chemistry.

Screening the Medicines for Malaria Venture Pathogen Box across Multiple Pathogens Reclassifies Starting Points for Open-Source Drug Discovery

V. Avery, B. Sleebs, Sandra Duffy, 2017, Antimicrobial Agents and Chemotherapy.

Synthesis and Evaluation of Antimalarial Properties of Novel 4‐Aminoquinoline Hybrid Compounds

K. Andrews, G. Fisher, S. Poulsen, 2014, Chemical biology & drug design.

Synthesis of Novel Saccharin Derivatives

S. Poulsen, Gregory M. Rankin, 2017, Molecules.

Synthesis and in Vivo Biological Evaluation of (68)Ga-Labeled Carbonic Anhydrase IX Targeting Small Molecules for Positron Emission Tomography.

P. Lambin, L. Dubois, C. Supuran, 2016, Journal of medicinal chemistry.

Anti-mycobacterial activity of a bis-sulfonamide.

Brendan L Wilkinson, A. Wright, T. Houston, 2007, Bioorganic & medicinal chemistry letters.

Microwave-accelerated cross-metathesis reactions of N-allyl amino acid substrates

S. Poulsen, L. Bornaghi, 2005 .

Mapping Selective Inhibition of the Cancer-Related Carbonic Anhydrase IX Using Structure-Activity Relationships of Glucosyl-Based Sulfamates.

C. Supuran, D. Vullo, R. McKenna, 2015, Journal of medicinal chemistry.

Structural Insights into Carbonic Anhydrase IX Isoform Specificity of Carbohydrate-Based Sulfamates

C. Supuran, D. Vullo, B. Mahon, 2014, Journal of medicinal chemistry.

Agents described in the Molecular Imaging and Contrast Agent Database for imaging carbonic anhydrase IX expression

S. Poulsen, D. Sneddon, 2014, Journal of enzyme inhibition and medicinal chemistry.

Labeling of Cellular DNA with a Cyclosal Phosphotriester Pronucleotide Analog of 5‐ethynyl‐2′‐deoxyuridine

A. Mackay-Sim, S. Poulsen, D. Zencak, 2015, Chemical biology & drug design.

A prodrug approach toward cancer-related carbonic anhydrase inhibition.

C. Supuran, D. Vullo, S. Charman, 2013, Journal of medicinal chemistry.

Synthesis of acylated glycoconjugates as templates to investigate in vitro biopharmaceutical properties.

David M. Shackleford, S. Charman, Marie Lopez, 2013, Bioorganic & medicinal chemistry letters.

N-Allyl-N-(2-nitrobenzenesulfonyl)-L-phenylalanine methyl ester

P. Healy, S. Poulsen, Cassandra L Noack, 2003 .

Investigation of pyrimidine nucleoside analogues as chemical probes to assess compound effects on the proliferation of Trypanosoma cruzi intracellular parasites

V. Avery, S. Poulsen, M. Sykes, 2020, PLoS neglected tropical diseases.

Characterisation of Photoaffinity‐Based Chemical Probes by Fluorescence Imaging and Native‐State Mass Spectrometry

P. Chrysanthopoulos, S. Poulsen, K. Tonissen, 2017, Chembiochem : a European journal of chemical biology.

Recent developments of small molecule chemical probes for fluorescence-based detection of human carbonic anhydrase II and IX

S. Poulsen, K. Tonissen, Kanae Teruya, 2016 .

Natural product coumarins that inhibit human carbonic anhydrases.

C. Supuran, D. Vullo, Rohan A. Davis, 2013, Bioorganic & medicinal chemistry.

Design and synthesis of thiourea compounds that inhibit transmembrane anchored carbonic anhydrases.

Brendan L Wilkinson, C. Supuran, A. Innocenti, 2012, Bioorganic & medicinal chemistry.

Synthesis of glycoconjugate carbonic anhydrase inhibitors by ruthenium-catalysed azide-alkyne 1,3-dipolar cycloaddition.

C. Supuran, A. Maresca, S. Poulsen, 2011, Bioorganic & medicinal chemistry letters.

Novel organometallic cationic ruthenium(II) pentamethylcyclopentadienyl benzenesulfonamide complexes targeted to inhibit carbonic anhydrase

C. Supuran, A. Innocenti, D. Vullo, 2009, JBIC Journal of Biological Inorganic Chemistry.

Inhibition of carbonic anhydrase isozymes with benzene sulfonamides incorporating thio, sulfinyl and sulfonyl glycoside moieties.

C. Supuran, A. Innocenti, D. Vullo, 2009, Bioorganic & medicinal chemistry letters.

Source Drug Discovery with the Malaria Box Compound Collection for Neglected Diseases and Beyond Citation

Alessandro, Serge, Tyler B. Hughes, 2016 .

Electrospray ionisation Fourier-transform ion cyclotron resonance mass spectrometry of dynamic combinatorial libraries.

P. Gates, G. R. Cousins, S. Poulsen, 2000, Rapid communications in mass spectrometry : RCM.

Synthetic utility of glycosyl triazoles in carbohydrate chemistry

Brendan L Wilkinson, T. Houston, S. Poulsen, 2006 .

Development of ethynyl-2'-deoxyuridine chemical probes for cell proliferation.

C. Lovitt, V. Avery, S. Poulsen, 2016, Bioorganic & medicinal chemistry.

Synthesis and structure-activity relationships of novel benzene sulfonamides with potent binding affinity for bovine carbonic anhydrase II.

P. Healy, S. Poulsen, L. Bornaghi, 2005, Bioorganic & medicinal chemistry letters.

Synthesis, structure and bioactivity of primary sulfamate-containing natural products.

C. Supuran, T. Peat, Silvia Bua, 2018, Bioorganic & medicinal chemistry letters.

Natural Product Primary Sulfonamides and Primary Sulfamates.

S. Poulsen, P. Mujumdar, 2015, Journal of natural products.

Carbonic Anhydrase XII Inhibitors Overcome Temozolomide Resistance in Glioblastoma.

C. Supuran, J. Kopecka, C. Riganti, 2019, Journal of medicinal chemistry.

P-glycoprotein-mediated chemoresistance is reversed by carbonic anhydrase XII inhibitors

J. Kopecka, C. Riganti, S. Poulsen, 2016, Oncotarget.

Pharmacological inhibition of carbonic anhydrase XII interferes with cell proliferation and induces cell apoptosis in T-cell lymphomas.

Thijs J. Hagenbeek, C. Supuran, V. Imbert, 2013, Cancer letters.

Natural Product Polyamines That Inhibit Human Carbonic Anhydrases

C. Supuran, D. Vullo, Rohan A. Davis, 2014, BioMed research international.

Pyrazolo[3,4-d]pyrimidines: C4, C6 substitution leads to adenosine A1 receptor selectivity

S. Poulsen, R. J. Quin, 1996 .

An Unusual Natural Product Primary Sulfonamide: Synthesis, Carbonic Anhydrase Inhibition, and Protein X-ray Structures of Psammaplin C.

C. Supuran, T. Peat, D. Vullo, 2016, Journal of medicinal chemistry.

Inhibition of carbonic anhydrase isozymes I, II and IX with benzenesulfonamides containing an organometallic moiety.

C. Supuran, A. Innocenti, D. Vullo, 2007, Bioorganic & medicinal chemistry letters.

Therapeutic applications of glycosidic carbonic anhydrase inhibitors

C. Supuran, J. Winum, S. Poulsen, 2009, Medicinal research reviews.

Antimalarial activity of compounds comprising a primary benzene sulfonamide fragment.

Marie Lopez, K. Andrews, G. Fisher, 2013, Bioorganic & medicinal chemistry letters.

Open Source Drug Discovery with the Malaria Box Compound Collection for Neglected Diseases and Beyond

Manuel Llinás, George Papadatos, Sundari Suresh, 2016, PLoS pathogens.

Synthesis and structure-activity relationship of pyrazolo[3,4-d]pyrimidines: potent and selective adenosine A1 receptor antagonists.

R. Quinn, S. Poulsen, 1996, Journal of medicinal chemistry.

Microwave-accelerated Fischer glycosylation

S. Poulsen, L. Bornaghi, 2005 .

Carbonic anhydrase inhibitors: inhibition of isozymes I, II, and IX with triazole-linked O-glycosides of benzene sulfonamides.

Brendan L Wilkinson, C. Supuran, A. Innocenti, 2007, Journal of medicinal chemistry.

Targeting hypoxic tumor cell viability with carbohydrate-based carbonic anhydrase IX and XII inhibitors.

C. Supuran, J. Pouysségur, Marie Lopez, 2011, Journal of medicinal chemistry.

Inhibition of carbonic anhydrases with glycosyltriazole benzene sulfonamides.

Brendan L Wilkinson, C. Supuran, A. Innocenti, 2008, Journal of medicinal chemistry.

Non-zinc mediated inhibition of carbonic anhydrases: coumarins are a new class of suicide inhibitors.

Ronald J. Quinn, Claudiu T. Supuran, Andrea Scozzafava, 2009, Journal of the American Chemical Society.

Synthesis of sulfonamide-bridged glycomimetics.

Sally-Ann Poulsen, H. Driguez, Marie Lopez, 2011, The Journal of organic chemistry.

Bifunctional copper(II) chelators from the coupling of the encapsulating ligand 1-methyl-8-amino-3,13,16-trithia-6,10,19-triazabicyclo[6.6.6]icosane (AMN3S3sar) with carboxylic acids; applications of the coupling agent DMT-MM

L. Gahan, Hui Hui Lee, S. Poulsen, 2015 .

Sulfonamide inhibition studies of the η-class carbonic anhydrase from the malaria pathogen Plasmodium falciparum.

C. Supuran, D. Vullo, C. Capasso, 2015, Bioorganic & medicinal chemistry.

Coumarins that inhibit carbonic anhydrase

S. Poulsen, 2014 .

Dynamic combinatorial libraries of pseudo-peptide hydrazone macrocycles

Jeremy K. M. Sanders, Sally-Ann Poulsen, Graham R. L. Cousins, 1999 .

Molecular evolution: dynamic combinatorial libraries, autocatalytic networks and the quest for molecular function.

G. R. Cousins, S. Poulsen, G R Cousins, 2000, Current opinion in chemical biology.

Synthesis of cyclic oligomers of a modified sugar amino acid utilising dynamic combinatorial chemistry

Brendan L Wilkinson, M. Kiefel, S. Poulsen, 2004 .

Direct screening of a dynamic combinatorial library using mass spectrometry

Sally-Ann Poulsen, S. Poulsen, 2006, Journal of the American Society for Mass Spectrometry.

Methyl 2,3,4-tri-O-acetyl-1-azido-1-deoxy-β-d-glucopyranuronate at room temperature

Brendan L Wilkinson, P. Healy, T. Houston, 2005 .

Natural product-based phenols as novel probes for mycobacterial and fungal carbonic anhydrases.

C. Supuran, A. Innocenti, D. Vullo, 2011, Journal of medicinal chemistry.

Carbonic anhydrase inhibitors. Identification of selective inhibitors of the human mitochondrial isozymes VA and VB over the cytosolic isozymes I and II from a natural product-based phenolic library.

C. Supuran, A. Innocenti, Rohan A. Davis, 2010, Bioorganic & medicinal chemistry.

Screening a natural product-based combinatorial library using FTICR mass spectrometry.

Rohan A Davis, Sally-Ann Poulsen, Rohan A. Davis, 2006, Bioorganic & medicinal chemistry.

Identification of a New Zinc Binding Chemotype by Fragment Screening.

T. Peat, B. Ren, O. Dolezal, 2017, Journal of medicinal chemistry.

Synthesis of N-Propargyl Iminosugar Scaffolds for Compound Library Generation using Click Chemistry

Brendan L Wilkinson, P. Healy, Marie Lopez, 2010 .

A novel class of carbonic anhydrase inhibitors: glycoconjugate benzene sulfonamides prepared by "click-tailing".

Brendan L Wilkinson, C. Supuran, A. Innocenti, 2006, Journal of medicinal chemistry.

Fragment-based drug discovery of carbonic anhydrase II inhibitors by dynamic combinatorial chemistry utilizing alkene cross metathesis.

Sally-Ann Poulsen, Laurent F Bornaghi, S. Poulsen, 2006, Bioorganic & medicinal chemistry.

Phosphate Chemical Probes Designed for Location Specific Inhibition of Intracellular Carbonic Anhydrases.

C. Supuran, D. Vullo, S. Poulsen, 2015, Journal of medicinal chemistry.

Stereoselective Synthesis of Highly Functionalized Arabinosyl Nucleosides through Application of an N-Nitro Protecting Group.

S. Poulsen, L. Bornaghi, D. Hilko, 2018, The Journal of organic chemistry.

Synthesis of 5‐Alkynyl Substituted 2ʹ‐Arabinosyl 2ʹ‐Halogenated Uridine Nucleosides

S. Poulsen, L. Bornaghi, D. Hilko, 2019, Current protocols in nucleic acid chemistry.

Adenosine receptors: new opportunities for future drugs.

R. Quinn, S. Poulsen, Ronald J. Quinn, 1998, Bioorganic & medicinal chemistry.

Saccharin: a lead compound for structure-based drug design of carbonic anhydrase IX inhibitors.

C. Supuran, B. Mahon, R. McKenna, 2015, Bioorganic & medicinal chemistry.

Discovery of a new family of carbonic anhydrases in the malaria pathogen Plasmodium falciparum--the η-carbonic anhydrases.

C. Supuran, D. Vullo, C. Capasso, 2014, Bioorganic & medicinal chemistry letters.

Cyclic secondary sulfonamides: unusually good inhibitors of cancer-related carbonic anhydrase enzymes.

C. Supuran, T. Peat, D. Vullo, 2014, Journal of medicinal chemistry.

Carbonic anhydrase inhibition as a cancer therapy: a review of patent literature, 2007 – 2009

S. Poulsen, 2010, Expert opinion on therapeutic patents.

S-glycosyl primary sulfonamides--a new structural class for selective inhibition of cancer-associated carbonic anhydrases.

C. Supuran, A. Innocenti, D. Vullo, 2009, Journal of medicinal chemistry.

Synthesis of S-glycosyl primary sulfonamides.

Marie Lopez, S. Poulsen, L. Bornaghi, 2009, The Journal of organic chemistry.

Carbonic anhydrase inhibitors with dual-tail moieties to match the hydrophobic and hydrophilic halves of the carbonic anhydrase active site.

C. Supuran, T. Peat, D. Vullo, 2015, Journal of medicinal chemistry.

Carbonic anhydrase XII inhibition overcomes P-glycoprotein-mediated drug resistance: a potential new combination therapy in cancer

S. Poulsen, K. Tonissen, 2021, Cancer drug resistance.

Carbonic Anhydrase XII Inhibitors Overcome P-Glycoprotein–Mediated Resistance to Temozolomide in Glioblastoma

D. Schiffer, J. Kopecka, C. Riganti, 2018, Molecular Cancer Therapeutics.

Metallocene-based inhibitors of cancer-associated carbonic anhydrase enzymes IX and XII.

C. Supuran, D. Vullo, S. Charman, 2012, Journal of medicinal chemistry.

Isoform-selective inhibitory profile of 2-imidazoline-substituted benzene sulfonamides against a panel of human carbonic anhydrases

C. Supuran, M. Tanc, S. Kalinin, 2016, Journal of enzyme inhibition and medicinal chemistry.

Inhibition of membrane-associated carbonic anhydrase isozymes IX, XII and XIV with a library of glycoconjugate benzenesulfonamides.

Brendan L Wilkinson, C. Supuran, A. Innocenti, 2007, Bioorganic & medicinal chemistry letters.

Protein crystal structures with ferrocene and ruthenocene-based enzyme inhibitors.

A. Hofmann, S. Poulsen, A. J. Salmon, 2012, Chemical communications.

An overview of Australia's compound management facility: the Queensland Compound Library.

Moana M. Simpson, S. Poulsen, 2014, ACS chemical biology.

Solution structures in aqueous SDS micelles of two amyloid beta peptides of A beta(1-28) mutated at the alpha-secretase cleavage site (K16E, K16F).

D. Craik, D. Fairlie, A. A. Watson, 2000, Journal of structural biology.

(η5-Pentamethylcyclopentadienyl)(η6-p-toluenesulfonamide)ruthenium(II) tetraphenylborate

P. Healy, S. Poulsen, M. Williams, 2008, Acta crystallographica. Section E, Structure reports online.

The Glitazone Class of Drugs as Carbonic Anhydrase Inhibitors—A Spin-Off Discovery from Fragment Screening

C. Supuran, T. Peat, T. Nebl, 2021, Molecules.

Investigating the antiplasmodial activity of primary sulfonamide compounds identified in open source malaria data

C. Supuran, C. Capasso, K. Andrews, 2017, International journal for parasitology. Drugs and drug resistance.

The Key Glycolytic Enzyme Phosphofructokinase Is Involved in Resistance to Antiplasmodial Glycosides

E. Winzeler, K. Saliba, M. McConville, 2020, mBio.

Fragment-based screening by X-ray crystallography, MS and isothermal titration calorimetry to identify PNMT (phenylethanolamine N-methyltransferase) inhibitors.

Hoan Vu, Sally-Ann Poulsen, Thomas E Prisinzano, 2010, The Biochemical journal.

Oxazole-Benzenesulfonamide Derivatives Inhibit HIV-1 Reverse Transcriptase Interaction with Cellular eEF1A and Reduce Viral Replication

D. Fairlie, D. Harrich, Jonathan M. Harris, 2019, Journal of Virology.

Thymidine kinase-independent click chemistry DNADetect™ probes for DNA proliferation assessment in malaria parasites

K. Andrews, G. Fisher, S. Poulsen, 2023, bioRxiv.