R. Sutliff

发表

The PPARgamma ligand, rosiglitazone, reduces vascular oxidative stress and NADPH oxidase expression in diabetic mice.

P. Thulé, C. Hart, Jinah Hwang, 2007, Vascular pharmacology.

Is peroxisome proliferator-activated receptor gamma (PPARγ) a therapeutic target for the treatment of pulmonary hypertension?

C. Hart, D. Green, R. Sutliff, 2011, Pulmonary circulation.

PPARγ as a potential therapeutic target in pulmonary hypertension

B. Kang, C. Hart, R. Sutliff, 2010, Therapeutic advances in respiratory disease.

Rosiglitazone attenuates chronic hypoxia-induced pulmonary hypertension in a mouse model.

C. Hart, D. Kleinhenz, R. Sutliff, 2010, American journal of respiratory cell and molecular biology.

PPARgamma as a potential therapeutic target in pulmonary hypertension

B. Kang, R. Sutliff, 2022 .

Insufficient nitric oxide bioavailability: a hypothesis to explain adverse effects of red blood cell transfusion

John D Roback, Arshed Quyyumi, A. Quyyumi, 2011, Transfusion.

Phospholamban regulation of bladder contractility: evidence from gene‐altered mouse models

E. Kranias, R. Paul, R. Sutliff, 2001, The Journal of physiology.

Decreased blood pressure and vascular smooth muscle tone in mice lacking basolateral Na(+)-K(+)-2Cl(-) cotransporter.

J. Lorenz, G. Shull, R. Paul, 2002, American journal of physiology. Heart and circulatory physiology.

Printed in U.S.A. Copyright © 1999 by The Endocrine Society Reduced Blood Pressure and Increased Sensitivity of the Vasculature to Parathyroid Hormone-Related Protein (PTHrP) in Transgenic Mice Overexpressing the PTH/ PTHrP Receptor in Vascular Smooth Mus

T. Clemens, J. Fagin, J. Lorenz, 2022 .

Regulation of the spontaneous contractile activity of the portal vein by the sarcoplasmic reticulum: evidence from the phospholamban gene-ablated mouse.

E. Kranias, L. Conforti, R. Paul, 2004, Vascular pharmacology.

Role of bradykinin in angiotensin-converting enzyme knockout mice.

K. Bernstein, R. Sutliff, S. Fuchs, 2003, American journal of physiology. Heart and circulatory physiology.

PPARγ attenuates hypoxia-induced hypertrophic transcriptional pathways in the heart

B. Kang, J. Calvert, R. Sutliff, 2017, Pulmonary circulation.

PPAR gamma attenuates hypoxia-induced hypertrophic transcriptional pathways in the heart

B. Kang, J. Calvert, C. Hart, 2022 .

Polymerase Delta Interacting Protein 2 Sustains Vascular Structure and Function

W. R. Taylor, K. Griendling, A. Amanso, 2013, Arteriosclerosis, thrombosis, and vascular biology.

HIV-1, reactive oxygen species, and vascular complications.

R. Sutliff, K. M. Porter, 2012, Free radical biology & medicine.

Peroxisome Proliferator‐Activated Receptor &ggr; Regulates the V‐Ets Avian Erythroblastosis Virus E26 Oncogene Homolog 1/microRNA‐27a Axis to Reduce Endothelin‐1 and Endothelial Dysfunction in the Sickle Cell Mouse Lung

B. Kang, T. Murphy, C. Hart, 2017, American journal of respiratory cell and molecular biology.

Lovastatin attenuates hypertension induced by renal tubule‐specific knockout of ATP‐binding cassette transporter A1, by inhibiting epithelial sodium channels

Zhi‐Ren Zhang, Ming‐Ming Wu, R. Sutliff, 2019, British journal of pharmacology.

Contractile Force Is Enhanced in Aortas from Pendrin Null Mice Due to Stimulation of Angiotensin II-Dependent Signaling

R. Bonsall, L. Walker, J. Verlander, 2014, PloS one.

Pendrin modulates ENaC function by changing luminal HCO3-.

A. Weinstein, D. Eaton, S. Wall, 2010, Journal of the American Society of Nephrology : JASN.

Reduced ENaC protein abundance contributes to the lower blood pressure observed in pendrin-null mice.

E. Green, J. Verlander, W. Beierwaltes, 2007, American journal of physiology. Renal physiology.

Candesartan treatment preserves learning and working memory in female TgF344-AD rats

N. Seyfried, I. Hajjar, E. Dammer, 2022, bioRxiv.

STZ-diabetic rats vascular function and improves adipocytokine profile in Hepatic insulin gene therapy prevents deterioration of

D. Olson, D. Kleinhenz, Adam G. Campbell, 2016 .

Hepatic insulin gene therapy prevents deterioration of vascular function and improves adipocytokine profile in STZ-diabetic rats.

P. Thulé, C. Hart, D. Olson, 2006, American journal of physiology. Endocrinology and metabolism.

Chronic Hypoxia Promotes Pulmonary Artery Endothelial Cell Proliferation through H2O2-Induced 5-Lipoxygenase

B. Kang, T. Murphy, C. Hart, 2014, PloS one.

Human immunodeficiency virus-1 transgene expression increases pulmonary vascular resistance and exacerbates hypoxia-induced pulmonary hypertension development

S. Elms, D. Guidot, R. Sutliff, 2013, Pulmonary circulation.

Peroxisome Proliferator-Activated Receptor γ and microRNA 98 in Hypoxia-Induced Endothelin-1 Signaling.

B. Kang, T. Murphy, C. Hart, 2016, American journal of respiratory cell and molecular biology.

Disruption of endothelial peroxisome proliferator-activated receptor-gamma reduces vascular nitric oxide production.

J. Ritzenthaler, C. Hart, D. Archer, 2009, American journal of physiology. Heart and circulatory physiology.

Tat 101-Mediated Enhancement of Brain Pericyte Migration Involves Platelet-Derived Growth Factor Subunit B Homodimer: Implications for Human Immunodeficiency Virus-Associated Neurocognitive Disorders

Honghong Yao, S. Buch, F. Niu, 2014, The Journal of Neuroscience.

Angiotensin II-induced hypertension in mice caused an increase in insulin secretion.

K. Bernstein, R. Sutliff, T. Doan, 2005, Vascular pharmacology.

Probing the Intracellular Delivery of Nanoparticles into Hard-to-Transfect Cells.

Steven R. Emory, Junya Chen, Wanchuan Ding, 2022, ACS nano.

HIV-1 transgene expression in rats causes oxidant stress and alveolar epithelial barrier dysfunction

Dean P. Jones, Michael Koval, D. Guidot, 2009, AIDS Research and Therapy.

Targeted Ablation of Plasma Membrane Ca2+-ATPase (PMCA) 1 and 4 Indicates a Major Housekeeping Function for PMCA1 and a Critical Role in Hyperactivated Sperm Motility and Male Fertility for PMCA4*

T. Doetschman, V. Prasad, G. Shull, 2004, Journal of Biological Chemistry.

Blood pressure regulates the activity and function of the Na-K-2Cl cotransporter in vascular smooth muscle.

W. C. O'Neill, F. Gordon, R. Sutliff, 2004, American journal of physiology. Heart and circulatory physiology.

Disruption of endothelial peroxisome proliferator-1 activated receptor gamma ( PPAR γ ) reduces vascular 2 nitric oxide production

D. Archer, D. Kleinhenz, R. Sutliff, 2009 .

Redox Biology of Peroxisome Proliferator-Activated Receptor-γ in Pulmonary Hypertension.

C. Hart, R. Sutliff, V. Tseng, 2019, Antioxidants & redox signaling.

Smooth Muscle-Targeted Overexpression of Peroxisome Proliferator Activated Receptor-γ Disrupts Vascular Wall Structure and Function

T. Murphy, C. Hart, R. Gleason, 2015, PloS one.

Smooth Muscle-Targeted Overexpression of Peroxisome Proliferator Activated Receptor-γ Disrupts Vascular Wall Structure and Function

T. Murphy, C. Hart, R. Gleason, 2015, PloS one.

HIV X4 Variants Increase Arachidonate 5-Lipoxygenase in the Pulmonary Microenvironment and are associated with Pulmonary Arterial Hypertension

B. Kang, K. Pruitt, S. Flores, 2020, Scientific Reports.

New insights into mechanisms regulating pulmonary adventitial fibroblast proliferation

R. Sutliff, 2017, Acta physiologica.

PPAR&ggr; Regulates Mitochondrial Structure and Function and Human Pulmonary Artery Smooth Muscle Cell Proliferation

B. Kang, T. Murphy, Gloria Torres, 2017, American journal of respiratory cell and molecular biology.

PPAR gamma Regulates Mitochondrial Structure and Function and Human Pulmonary Artery Smooth Muscle Cell Proliferation

B. Kang, T. Murphy, Gloria Torres, 2022 .

3’UTR shortening of HAS2 promotes hyaluronan hyper-synthesis and bioenergetic dysfunction in pulmonary hypertension

E. Wagner, B. Kang, R. Thandavarayan, 2022, Matrix biology : journal of the International Society for Matrix Biology.

Targeting mitochondrial reactive oxygen species to modulate hypoxia-induced pulmonary hypertension.

B. Kang, T. Murphy, R. Sutliff, 2015, Free radical biology & medicine.

Endothelial Cell Peroxisome Proliferator–Activated Receptor γ Reduces Endotoxemic Pulmonary Inflammation and Injury

C. Hart, Raju C Reddy, R. Sutliff, 2012, The Journal of Immunology.

Phospholamban is present in endothelial cells and modulates endothelium-dependent relaxation. Evidence from phospholamban gene-ablated mice.

E. Kranias, R. Paul, J. Hoying, 1999, Circulation research.

Hypoxia Mediates Mutual Repression between microRNA-27a and PPARγ in the Pulmonary Vasculature

B. Kang, C. Hart, J. West, 2013, PloS one.

Hypoxia Mediates Mutual Repression between microRNA-27a and PPAR gamma in the Pulmonary Vasculature

B. Kang, D. Green, C., 2022 .

Chronic ethanol ingestion increases superoxide production and NADPH oxidase expression in the lung.

R. Clempus, C. Hart, D. Campbell, 2006, American journal of respiratory cell and molecular biology.

Smooth muscle-targeted overexpression of insulin-like growth factor I results in enhanced vascular contractility.

J. Fagin, J. Lorenz, R. Paul, 2001, Endocrinology.

Endothelial Dysfunction, Arterial Stiffening, and Intima-Media Thickening in Large Arteries from HIV-1 Transgenic Mice

M. Platt, R. Gleason, R. Sutliff, 2012, Annals of Biomedical Engineering.

Low‐dose oral cadmium increases airway reactivity and lung neuronal gene expression in mice

Dean P. Jones, D. Barr, Y. Go, 2016, Physiological reports.

HIV‐1 Induced Pulmonary Oxidative and Nitrosative Stress: Exacerbated Response to Endotoxin Administration in an HIV‐1 Transgenic Mouse Model

Dean P. Jones, P. Cheng, R. Sutliff, 2006, American journal of physiology. Lung cellular and molecular physiology.

Hypoxia inhibits expression and function of mitochondrial thioredoxin 2 to promote pulmonary hypertension.

B. Kang, Y. Go, C. Hart, 2017, American journal of physiology. Lung cellular and molecular physiology.

Anti‐inflammatory and analgesic activity of the bradykinin antagonist, icatibant (Hoe 140), against an extract from Porphyromonas gingivalis

F. Lembeck, R. Sutliff, T. Griesbacher, 1994, British journal of pharmacology.

Chronic ethanol ingestion increases aortic endothelial nitric oxide synthase expression and nitric oxide production in the rat.

S. Dikalov, C. Hart, D. Guidot, 2007, Alcoholism, clinical and experimental research.

PPARγ/ETV2 Axis Regulates Endothelial-to-Mesenchymal Transition in Pulmonary Hypertension

W. Lam, R. Benza, B. Kang, 2022, bioRxiv.

The Nox4 inhibitor GKT137831 attenuates hypoxia-induced pulmonary vascular cell proliferation.

B. Kang, T. Murphy, C. Hart, 2012, American journal of respiratory cell and molecular biology.

Vasorelaxant properties of parathyroid hormone-related protein in the mouse: evidence for endothelium involvement independent of nitric oxide formation.

T. Clemens, M. Miller, C. Weber, 1999, Endocrinology.

Red blood cells stored for increasing periods produce progressive impairments in nitric oxide–mediated vasodilation

James L. Newman, D. Lefer, J. Roback, 2013, Transfusion.

Targeted overexpression of parathyroid hormone-related protein (PTHrP) to vascular smooth muscle in transgenic mice lowers blood pressure and alters vascular contractility.

T. Clemens, D. Witte, J. Fagin, 1999, Endocrinology.

Effect of the Na-K-2Cl cotransporter NKCC1 on systemic blood pressure and smooth muscle tone.

W. C. O'Neill, S. Wall, C. Garland, 2007, American journal of physiology. Heart and circulatory physiology.

Proline-Rich Tyrosine Kinase 2 Downregulates Peroxisome Proliferator–Activated Receptor Gamma to Promote Hypoxia-Induced Pulmonary Artery Smooth Muscle Cell Proliferation

B. Kang, C. Hart, R. Sutliff, 2016, Pulmonary circulation.

PPARγ depletion stimulates Nox4 expression and human pulmonary artery smooth muscle cell proliferation

B. Kang, T. Murphy, C. Hart, 2015 .

Pulmonary Inflammation and Injury Reduces Endotoxemic g Activated Receptor - Endothelial Cell Peroxisome Proliferator

C. Hart, Raju C Reddy, R. Sutliff, 2012 .

Peroxisome proliferator-activated receptor gamma depletion stimulates Nox4 expression and human pulmonary artery smooth muscle cell proliferation.

B. Kang, T. Murphy, C. Hart, 2015, Free radical biology & medicine.

Azidothymidine (AZT) leads to arterial stiffening and intima-media thickening in mice.

M. Platt, R. Gleason, R. Sutliff, 2013, Journal of biomechanics.

The Role of Intercalated Cell Nedd4-2 in BP Regulation, Ion Transport, and Transporter Expression.

Xiaonan H. Wang, R. Chambrey, Masayoshi Nanami, 2018, Journal of the American Society of Nephrology : JASN.

Cocaine Increases Mortality and Cardiac Mass in a Murine Transgenic Model of Acquired Immune Deficiency Syndrome

B. Hoit, Rodney B Russ, W. Lewis, 2003, Laboratory Investigation.

Cardiovascular hypertrophy and increased vascular contractile responsiveness following repeated cocaine administration in rabbits.

J. Roberts, M. Johnson, H. Gurdal, 1996, Life sciences.

Pro-Atherogenic Shear Stress and HIV Proteins Synergistically Upregulate Cathepsin K in Endothelial Cells

M. Platt, R. Gleason, R. Sutliff, 2014, Annals of Biomedical Engineering.

Hypoxia-Induced Alterations In MicroRNA-21 And -17-92 In Pulmonary Vascular Cells: Regulation By PPARg

B. Kang, C. Hart, D. Green, 2012, ATS 2012.

Nucleoside reverse transcriptase inhibitors impair endothelium-dependent relaxation by increasing superoxide.

D. Weiss, S. Dikalov, Rodney B Russ, 2002, American journal of physiology. Heart and circulatory physiology.

GDNF rescues hyperglycemia-induced diabetic enteric neuropathy through activation of the PI3K/Akt pathway.

S. Srinivasan, M. Anitha, S. Mwangi, 2006, The Journal of clinical investigation.

Diastolic dysfunction is associated with cardiac fibrosis in the senescence-accelerated mouse.

D. Sorescu, S. Dudley, R. Sutliff, 2011, American journal of physiology. Heart and circulatory physiology.

Use of senescence-accelerated mouse model in bleomycin-induced lung injury suggests that bone marrow-derived cells can alter the outcome of lung injury in aged mice.

Valerie Mac, M. Rojas, K. Brigham, 2009, The journals of gerontology. Series A, Biological sciences and medical sciences.

Long-Term Exposure to AZT, but not d4T, Increases Endothelial Cell Oxidative Stress and Mitochondrial Dysfunction

Dean P. Jones, R. Schinazi, S. Dikalov, 2009, Cardiovascular Toxicology.

Defective Endothelium-dependent Relaxation of Vascular Smooth Muscle and Endothelial Cell Ca2+ Signaling in Mice Lacking Sarco(endo)plasmic Reticulum Ca2+-ATPase Isoform 3*

T. Doetschman, J. Lorenz, G. Shull, 1997, The Journal of Biological Chemistry.

Fibroblast growth factor 2 control of vascular tone

S. Pawlowski, M. Yin, G. Boivin, 1998, Nature Medicine.

MicroRNA-155 Modulates Macrophages’ Response to Non-Tuberculous Mycobacteria through COX-2/PGE2 Signaling

F. E. Lee, R. Sadikot, B. Bedi, 2021, Pathogens.

Macrophage Signaling Pathways in Pulmonary Nontuberculous Mycobacteria Infections.

R. Sadikot, R. Sutliff, Z. Prasla, 2020, American journal of respiratory cell and molecular biology.

Polycomb group protein CBX7 represses cardiomyocyte proliferation via modulation of the TARDBP/Rbm38 axis

J. Calvert, Y. Yoon, A. Husain, 2021, bioRxiv.

Vascular oxidative stress and nitric oxide depletion in HIV-1 transgenic rats are reversed by glutathione restoration.

Dean P. Jones, S. Dikalov, C. Hart, 2008, American journal of physiology. Heart and circulatory physiology.

Cardiovascular effects of acute and chronic cocaine administration in pregnant and nonpregnant rabbits.

J. Roberts, M. Johnson, D. Snyder, 1999, Toxicology and applied pharmacology.

High-performance metabolic profiling of plasma from seven mammalian species for simultaneous environmental chemical surveillance and bioeffect monitoring.

Dean P. Jones, Dean P Jones, Kichun Lee, 2012, Toxicology.

Mice Lacking Endothelial ACE: Normal Blood Pressure With Elevated Angiotensin II

M. Capecchi, P. Corvol, K. Bernstein, 2003, Hypertension.

The Roles of HIV-1 Proteins and Antiretroviral Drug Therapy in HIV-1-Associated Endothelial Dysfunction

R. Sutliff, Erik R. Kline, 2008, Journal of Investigative Medicine.

An In Vivo Murine Model of Low-Magnitude Oscillatory Wall Shear Stress to Address the Molecular Mechanisms of Mechanotransduction—Brief Report

Don P Giddens, John N Oshinski, Robert E Guldberg, 2010, Arteriosclerosis, thrombosis, and vascular biology.

Lack of angiotensin II-facilitated erythropoiesis causes anemia in angiotensin-converting enzyme-deficient mice.

M. Capecchi, E. Ezan, P. Corvol, 2000, The Journal of clinical investigation.

Effect of medial calcification on vascular function in uremia.

W. C. O'Neill, K. Lomashvili, R. Sutliff, 2011, American journal of physiology. Renal physiology.

Low-Dose Cadmium Causes Metabolic and Genetic Dysregulation Associated With Fatty Liver Disease in Mice.

Dean P. Jones, B. Fowler, F. Anania, 2015, Toxicological sciences : an official journal of the Society of Toxicology.

The cofilin phosphatase slingshot homolog 1 restrains angiotensin II-induced vascular hypertrophy and fibrosis in vivo

D. Weiss, B. Lassègue, A. San Martin, 2018, Laboratory Investigation.

The Role of Peroxisome Proliferator-Activated Receptors in Pulmonary Vascular Disease

J. Roman, C. Hart, R. Sutliff, 2007, PPAR research.

The role of NADPH oxidase in chronic intermittent hypoxia-induced pulmonary hypertension in mice.

C. Hart, D. Kleinhenz, H. L. Rupnow, 2009, American journal of respiratory cell and molecular biology.

Hypoxia-induced alterations in the lung ubiquitin proteasome system during pulmonary hypertension pathogenesis

Jing Ma, C. Hart, Jingru Zhao, 2018, Pulmonary circulation.

upregulation in hyperglycemia-activated endothelial cells

Xianghuai Lu, R. Sutliff, C. Michael, 2016 .

Rosiglitazone attenuates NF-κB-mediated Nox4 upregulation in hyperglycemia-activated endothelial cells.

Xianghuai Lu, C. Hart, R. Sutliff, 2012, American journal of physiology. Cell physiology.

PPARγ increases HUWE1 to attenuate NF-κB/p65 and sickle cell disease with pulmonary hypertension.

R. Benza, B. Kang, C. Hart, 2021, Blood advances.

MicroRNA-98 reduces nerve growth factor expression in nicotine-induced airway remodeling

B. Kang, T. Nyunoya, C. Hart, 2020, The Journal of Biological Chemistry.

Combined Antiretroviral Therapy Causes Cardiomyopathy and Elevates Plasma Lactate in Transgenic AIDS Mice

William Lewis, A. Samarel, B. Hoit, 2001, Laboratory Investigation.

[Ca2+]ihomeostasis and cyclic nucleotide relaxation in aorta of phospholamban-deficient mice.

E. Kranias, R. Paul, S. Shimizu, 1999, American journal of physiology. Heart and circulatory physiology.

[Ca 2 1 ] i homeostasis and cyclic nucleotide relaxation in aorta of phospholamban-deﬁcient mice

E. Kranias, R. Paul, S. Shimizu, 1999 .

Is myosin phosphatase regulated in vivo by inhibitor‐1? Evidence from inhibitor‐1 knockout mice

Andrew N. Carr, P. Greengard, P. Allen, 2001, The Journal of physiology.

Smooth Muscle Studies Using Gene-Altered Mouse Models: A Users’ Guide

R. Paul, R. Sutliff, 2001 .

Increased Transglutaminase 2 Expression and Activity in Rodent Models of Obesity/Metabolic Syndrome and Aging

A. Leite-Moreira, B. Fanburg, I. Falcão-Pires, 2020, Frontiers in Physiology.

Myoglobinemia, Peripheral Arterial Disease, and Patient Mortality

W. Jordan, L. Brewster, P. Koutakis, 2023, Journal of the American College of Surgeons.

Polycomb Group Protein CBX7 Represses Cardiomyocyte Proliferation Through Modulation of the TARDBP/RBM38 Axis

Y. Yoon, J. Calvert, A. Husain, 2023, Circulation.

Pendrin localizes to the adrenal medulla and modulates catecholamine release.

S. Sen, A. Osunkoya, P. Plotsky, 2015, American journal of physiology. Endocrinology and metabolism.

Targeted myocardial transgenic expression of HIV Tat causes cardiomyopathy and mitochondrial damage.

A. Samarel, B. Hoit, B. Day, 2002, American journal of physiology. Heart and circulatory physiology.

PPARγ Activation Reduces Hypoxia-induced Endothelin-1 Expression through Upregulation of miR-98.

B. Kang, T. Murphy, R. Sutliff, 2015 .

Reduced blood pressure and increased sensitivity of the vasculature to parathyroid hormone-related protein (PTHrP) in transgenic mice overexpressing the PTH/PTHrP receptor in vascular smooth muscle.

T. Clemens, J. Fagin, T. Nakayama, 1999, Endocrinology.

Targeted overexpression of parathyroid hormone-related protein (PTHrP) to vascular smooth muscle in transgenic mice lowers blood pressure and alters vascular contractility.

T. Clemens, J. Fagin, T. Nakayama, 1999, Endocrinology.

Tat 101-Mediated Enhancement of Brain Pericyte Migration Involves Platelet-Derived Growth Factor Subunit B Homodimer: Implications for Human Immunodeficiency Virus-Associated Neurocognitive Disorders

Honghong Yao, S. Buch, F. Niu, 2014, The Journal of Neuroscience.

HIV‐1 Tat increases hydrogen peroxide and 5‐lipoxygenase in pulmonary artery endothelial cells

R. Sutliff, W. Tyor, K. M. Porter, 2011 .

Evidence From Phospholamban Gene-Ablated Mice Phospholamban Is Present in Endothelial Cells and Modulates Endothelium-Dependent

J. Hoying, R. Sutliff, Vivek J. Kadambi, 1999 .

Redox Biology of Peroxisome Proliferator-Activated Receptor- c in Pulmonary Hypertension c , pulmonary hypertension, hypoxia, oxidative stress, antioxidants, thiazolidinedione

R. Sutliff, C. M. Hart, Victor Tseng, 2019 .

Pendrin localizes to the adrenal medulla and modulates catecholamine release.

S. Sen, A. Osunkoya, P. Plotsky, 2015, American journal of physiology. Endocrinology and metabolism.

High-performance metabolic profiling of plasma from seven mammalian species for simultaneous environmental chemical surveillance and bioeffect monitoring.

Dean P. Jones, Frederick H. Strobel, K. Mansfield, 2012, Toxicology.