C. Dobkin

发表

Rapid fragile X carrier screening and prenatal diagnosis using a nonradioactive PCR test.

W. Brown, A. Jeziorowska, S. Brooks, 1994, JAMA.

Gamma delta beta-thalassemia due to a de novo mutation deleting the 5' beta-globin gene activation-region hypersensitive sites.

B. Alter, C. Dobkin, M. Driscoll, 1989, Proceedings of the National Academy of Sciences of the United States of America.

The Role of Template Structure in the Recognition Mechanism of Qβ Replicase

F. Kramer, D. Mills, S. Spiegelman, 1977 .

Hypothesis regarding the nature of the fragile X mutation

W. Brown, S. Sherman, C. Dobkin, 1987, Human Genetics.

Pulsed-field gradient-gel studies around the fragile site.

W. Brown, C. Dobkin, 1988, American journal of medical genetics.

A PvuII RFLP detected in the human prion protein (PrP) gene.

H. Wiśniewski, N. Robakis, C. Dobkin, 1987, Nucleic acids research.

In situ nick translation of the fragile X region.

W. Brown, S. Nolin, E. Jenkins, 1988, American journal of medical genetics.

3-Hydroxyacyl-CoA and Alcohol Dehydrogenase Activities of Mitochondrial Type 10 17β-Hydroxysteroid Dehydrogenase in Neurodegeneration Study

Song-Yu Yang, C. Dobkin, Xue‐Ying He, 2022, Journal of Alzheimer's disease : JAD.

Reply to “FRAXAC2 instability”

W. Brown, C. Dobkin, N. Zhong, 1994, Nature Genetics.

Cloning the ends of size selected Sfi I fragments.

S. Nolin, C. Dobkin, 1991, American journal of medical genetics.

Fragile X screening by quantification of FMRP in dried blood spots by a Luminex immunoassay.

W. Brown, G. Lafauci, S. Nolin, 2013, The Journal of molecular diagnostics : JMD.

A novel cysteine sulfinic Acid decarboxylase knock-out mouse: comparison between newborn and weanling mice.

E. Park, G. Schuller-Levis, Seung-Yong Park, 2015, Advances in experimental medicine and biology.

A Genotype-Phenotype Study of High-Resolution FMR1 Nucleic Acid and Protein Analyses in Fragile X Patients with Neurobehavioral Assessments

W. Brown, W. Kaufmann, E. Mahone, 2020, Brain sciences.

Modification of cytidines in a Q beta replicase template: analysis of conformation and localization of lethal nucleotide substitutions.

F. Kramer, D. Mills, P. E. Cole, 1980, Biochemistry.

RNA replication: required intermediates and the dissociation of template, product, and Q beta replicase.

F. Kramer, D. Mills, S. Spiegelman, 1979, Biochemistry.

Reduced mRNA for G3BP in fragile X cells: evidence of FMR1 gene regulation.

D. Nelson, W. Brown, C. Dobkin, 1999, American journal of medical genetics.

Identification of Fragile X Syndrome Specific Molecular Markers in Human Fibroblasts: A Useful Model to Test the Efficacy of Therapeutic Drugs

E. Klann, C. B. Smith, Kristen Moulton, 2014, Human mutation.

Human type I cytokeratin genes are a compact cluster.

P. Bosco, J. Cassiman, R. Leube, 1997, Cytogenetics and cell genetics.

The Fragile X Syndrome a

W. Brown, I. Cohen, G. Fisch, 1986, Australian family physician.

Does the HSD17B10 gene escape from X-inactivation?

Song-Yu Yang, Song-Yu Yang, Xue-Ying He, 2011, European Journal of Human Genetics.

RNA primer used in synthesis of anticomplementary DNA by reverse transcriptase of avian myeloblastosis virus.

J. C. Myers, S. Spiegelman, C. Dobkin, 1980, Proceedings of the National Academy of Sciences of the United States of America.

Prenatal fragile X detection using cytoplasmic and nuclear-specific monoclonal antibodies.

W. Brown, S. Nolin, K. Kim, 1999, American journal of medical genetics.

Mosaicism in fragile X affected males.

W. Brown, S. Nolin, G. Houck, 1994, American journal of medical genetics.

Mosaicism for the FMR1 gene influences adaptive skills development in fragile X-affected males.

W. Brown, I. Cohen, S. Nolin, 1996, American journal of medical genetics.

Terminal deletions of the long arm of chromosome X that include the FMR1 gene in female patients: A case series

Naomi Yachelevich, S. Nolin, S. Brooks, 2011, American journal of medical genetics. Part A.

Reversibility of IVS 2 missplicing in a mutant human beta-globin gene.

A. Bank, C. Dobkin, 1985, The Journal of biological chemistry.

Premutation female carriers of fragile X syndrome: a pilot study on brain anatomy and metabolism.

P. Pietrini, C. Grady, B. Horwitz, 1999, Journal of the American Academy of Child and Adolescent Psychiatry.

Fragile X protein in newborn dried blood spots

W. Brown, G. Lafauci, M. Field, 2014, BMC Medical Genetics.

Erythroleukemia (K562) cells contain a functional beta-globin gene

A. Bank, C. Dobkin, M. Donovan‐Peluso, 1984, Molecular and cellular biology.

Polymorphism of FXR1 showing lack of association with autism.

W. Brown, P. Limprasert, C. Dobkin, 1997, American journal of medical genetics.

Abnormal Globin Gene Structure and Expression in β‐Thalassemia

A. Bank, C. Dobkin, M. Donovan‐Peluso, 1985 .

Expression of human gamma-globin genes in human erythroleukemia (K562) cells.

A. Bank, C. Dobkin, S. Acuto, 1987, The Journal of biological chemistry.

Beta-thalassemia syndromes.

A. Bank, C. Dobkin, 1987, Birth defects original article series.

Prenatal diagnosis of fragile X syndrome

K. Davies, W. Brown, F. Rousseau, 1991, The Lancet.

Nucleotide sequence of microvariant RNA: another small replicating molecule.

F. Kramer, D. Mills, C. Dobkin, 1975, Proceedings of the National Academy of Sciences of the United States of America.

A high frequency NcoI RFLP detected in the Alzheimer amyloid peptide gene.

H. Wiśniewski, N. Robakis, W. Brown, 1988, Nucleic acids research.

A survey of FRAXE allele sizes in three populations.

W. Brown, M. Ryynänen, C. Pang, 1996, American journal of medical genetics.

Regulated expression of amplified human beta globin genes.

A. Bank, C. Dobkin, D. Rund, 1987, Blood.

Development of a Novel Cysteine Sulfinic Acid Decarboxylase Knockout Mouse: Dietary Taurine Reduces Neonatal Mortality

Seung Yong Park, E. Park, G. Schuller-Levis, 2014, Journal of amino acids.

Three regions upstream from the cap site are required for efficient and accurate transcription of the rabbit β-globin gene in mouse 3T6 cells

J. Reiser, M. Cochran, C. Weissmann, 1983, Cell.

Linkage in fragile X families of three distal flanking markers: ST14, DX13, and F8.

W. Brown, E. Jenkins, C. Dobkin, 1991, American journal of medical genetics.

Linkage analysis of the fragile X syndrome using a new DNA marker U6.2 defining locus DXS304.

P. Bosco, W. Brown, U. Pettersson, 1991, American journal of medical genetics.

IL-6 is increased in the cerebellum of autistic brain and alters neural cell adhesion, migration and synaptic formation

A. Sheikh, W. Brown, M. Malik, 2011, Journal of Neuroinflammation.

Regulation of human globin gene expression.

A. Bank, C. Dobkin, M. Donovan‐Peluso, 1985, Progress in clinical and biological research.

Fmr1 knockout mouse has a distinctive strain-specific learning impairment

W. Brown, Carl Dobkin, C. Dobkin, 2000, Neuroscience.

Five nucleotide changes in the large intervening sequence of a β globin gene in a β + thalassemia patient

R. Pergolizzi, A. Bank, C. Dobkin, 1982 .

The Therapeutic effect of Memantine through the Stimulation of Synapse Formation and Dendritic Spine Maturation in Autism and Fragile X Syndrome

A. Sheikh, W. Brown, M. Malik, 2012, PloS one.

Decreased GABAA receptor expression in the seizure-prone fragile X mouse

W. Brown, C. Dobkin, A. El Idrissi, 2005, Neuroscience Letters.

Transcription start sites and epigenetic analysis of the HSD17B10 proximal promoter

W. Brown, Song-Yu Yang, C. Dobkin, 2013, BMC Biochemistry.

17β-Hydroxysteroid dehydrogenases and neurosteroid metabolism in the central nervous system

Song-Yu Yang, C. Dobkin, Xue‐Ying He, 2019, Molecular and Cellular Endocrinology.

Terminal adenylation in the synthesis of RNA by Q beta replicase.

F. Kramer, D. Mills, C. Dobkin, 1983, The Journal of biological chemistry.

Neuroendocrine alterations in the fragile X mouse.

W. Brown, W. L'amoreaux, C. Dobkin, 2012, Results and problems in cell differentiation.

Molecular characterization of a DNA probe, U6.2, located close to the fragile X locus.

W. Brown, U. Pettersson, R. Pergolizzi, 1991, American journal of medical genetics.

Fragile X analysis of 1112 prenatal samples from 1991 to 2010

W. Brown, S. Nolin, Nicole Ersalesi, 2011, Prenatal diagnosis.

Expansions and contractions of the FMR1 CGG repeat in 5,508 transmissions of normal, intermediate, and premutation alleles

A. Vianna-Morgante, M. Milá, S. Nolin, 2019, American journal of medical genetics. Part A.

Fragile X full mutation expansions are inhibited by one or more AGG interruptions in premutation carriers

W. Brown, Sachin Sah, S. Nolin, 2014, Genetics in Medicine.

Tissue differences in fragile X mosaics: mosaicism in blood cells may differ greatly from skin.

W. Brown, M. Bialer, I. Cohen, 1996, American journal of medical genetics.

Multipoint linkage of 9 anonymous probes to HPRT, factor 9, and fragile X.

W. Brown, W. Ye, E. Jenkins, 1988, American journal of medical genetics.

RFLP FOR LINKAGE ANALYSIS OF FRAGILE X SYNDROME

W. Brown, C. Dobkin, EdmundC. Jenkins, 1987, The Lancet.

Fragile X prenatal analyses show full mutation females at high risk for mosaic Turner syndrome: Fragile X leads to chromosome loss

S. Nolin, Gabriela Radu, W. Brown, 2009, American journal of medical genetics. Part A.

Reverse mutations in the fragile X syndrome.

W. Brown, S. Nolin, E. Jenkins, 1994, American journal of medical genetics.

Mode of inheritance influences behavioral expression and molecular control of cognitive deficits in female carriers of the fragile X syndrome.

W. Brown, J. Halperin, I. Cohen, 1992, American journal of medical genetics.

Cytogenetically negative, linkage positive "fragile X" syndrome.

W. Brown, I. Cohen, E. Jenkins, 1991, American journal of medical genetics.

Cognitive and molecular aspects of fragile X.

W. Brown, J. Halperin, V. Hinton, 1995, Journal of clinical and experimental neuropsychology.

Abnormal splice in a mutant human beta-globin gene not at the site of a mutation.

R. Pergolizzi, A Bank, A. Bank, 1983, Proceedings of the National Academy of Sciences of the United States of America.

MODIFICATION OF THE RABBIT CHROMOSOMAL β-GLOBIN GENE BY RESTRUCTURING AND SITE-DIRECTED MUTAGENESIS

P. Abrescia, E. Mullen, C. Weissmann, 1981 .

Expression of a cloned Lepore globin gene.

A. Bank, J. Clyne, C. Dobkin, 1986, Blood.

FMR1 CGG-repeat instability in single sperm and lymphocytes of fragile-X premutation males.

W. Brown, S. Nolin, G. Houck, 1999, American journal of human genetics.

Fragile X founder effects and new mutations in Finland.

W. Brown, M. Ryynänen, S. Nolin, 1996, American journal of medical genetics.

Rapid Fragile X Carrier Screening and Prenatal Diagnosis Using a Nonradioactive PCR Test

W. Brown, A. Jeziorowska, S. Brooks, 1993 .

Polymerase chain reaction analysis of fragile X mutations

S. Erster, R. Pergolizzi, E. Jenkins, 1992, Human Genetics.

Detection of fragile X non-penetrant males by DNA marker analysis.

W. Brown, E. Jenkins, C. Dobkin, 1991, American journal of medical genetics.

PFGE of human DNA: 5-azacytidine improves restriction.

C. Dobkin, W. Brown, C. Ferrando, 1987, Nucleic acids research.

A Do-it-Yourself Protocol for Making Desired Mutant Proteins

C. Dobkin, Xue‐Ying He, song‐yu yang, 2017 .

Fragile X screening program in New York State.

W. Brown, S. Nolin, E. Jenkins, 1991, American journal of medical genetics.

DNA sequences regulating human β globin gene expression

A. Bank, C. Dobkin, K. Kosche, 1985 .

Fragile X founder chromosome effects: linkage disequilibrium or microsatellite heterogeneity?

W. Brown, C. Dobkin, N. Zhong, 1994, American journal of medical genetics.

Distribution of FMR-1 and associated microsatellite alleles in a normal Chinese population.

W. Brown, G. Houck, C. Dobkin, 1994, American journal of medical genetics.

A complex mutable polymorphism located within the fragile X gene

W. Brown, C. Dobkin, N. Zhong, 1993, Nature Genetics.

Roles of 17β-hydroxysteroid dehydrogenase type 10 in neurodegenerative disorders

Song-Yu Yang, David Miller, C. Isaacs, 2014, The Journal of Steroid Biochemistry and Molecular Biology.

Tissue and developmental regulation of fragile X mental retardation 1 exon 12 and 15 isoforms

G. Lafauci, W. Xie, R. Denman, 2009, Neurobiology of Disease.

Template-determined, variable rate of RNA chain elongation

Fred Russell Kramer, Donald R. Mills, F. Kramer, 1978, Cell.

Fragile X gene instability: anchoring AGGs and linked microsatellites.

W. Brown, Wei-Hsien Yang, W. Yang, 1995, American journal of human genetics.

Prenatal diagnosis and carrier screening for fragile X by PCR.

W. Brown, S. Nolin, E. Jenkins, 1996, American journal of medical genetics.

Fragile X AGG analysis provides new risk predictions for 45–69 repeat alleles

W. Brown, R. Shroff, F. Tassone, 2013, American journal of medical genetics. Part A.

Reply to Duncan: Fragile X leads to X chromosome loss: Comments from a cytogeneticist

S. Nolin, C. Dobkin, W. Brown, 2010 .

Fragile X "gray zone" alleles: AGG patterns, expansion risks, and associated haplotypes.

W. Brown, C. Dobkin, N. Zhong, 1996, American journal of medical genetics.

Reduced mRNA for G3BP in fragile X cells: Evidence of FMR1 gene regulation

D. Nelson, W. Brown, C. Dobkin, 1999 .

Accelerated prenatal diagnosis of fragile X syndrome by polymerase chain reaction restriction fragment detection.

W. Brown, S. Nolin, E. Jenkins, 1999, American journal of medical genetics.

Infantile Neurodegeneration results from Mutants of 17β‐Hydroxysteroid Dehydrogenase Type 10 rather than Aβ‐Binding Alcohol Dehydrogenase

Song-Yu Yang, C. Dobkin, Xue‐Ying He, 2022, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

A 5-methylcytosine hotspot responsible for the prevalent HSD17B10 mutation.

W. Brown, Song-Yu Yang, C. Dobkin, 2013, Gene.

Mental Retardation and Isoleucine Metabolism

W. Brown, Song-Yu Yang, C. Isaacs, 2015 .

A glycine to serine polymorphism in the C-propeptide of the human type II procollagen.

H. Vissing, M. D’Alessio, F. Ramirez, 1990, Nucleic acids research.

Molecular Analysis of Fragile X Syndrome

S. Nolin, C. Dobkin, W. Brown, 2003, Current protocols in human genetics.

Fragile X full mutation alleles composed of few alleles: Implications for CGG repeat expansion

S. Nolin, G. Houck, C. Dobkin, 2008, American journal of medical genetics. Part A.

Polymerase chain reaction detection of the Dde I polymorphism in the factor 9 gene for fragile X linkage analysis.

C. Dobkin, M. Driscoll, C. Ferrando, 1991, American journal of medical genetics.

Molecular carrier testing for the fragile X syndrome: Issues for genetic counselors

W. Brown, S. Nolin, S. Brooks, 1994, Journal of Genetic Counseling.

Fragile X screening by quantification of FMRP in dried blood spots by a Luminex immunoassay.

G. Lafauci, S. Nolin, T. Adayev, 2013, The Journal of molecular diagnostics : JMD.

Prenatal diagnosis and carrier screening for fragile X by PCR.

G. Houck, C. Dobkin, Anne C. Glicksman, 1996, American journal of medical genetics.

New York State screening program for fragile X syndrome: a progress report.

S. Nolin, E. Jenkins, C. Dobkin, 1992, American journal of medical genetics.