D. Gin

发表

Enantioselective Total Synthesis of Ecteinascidin 743

E. Corey, R. Kania, E. J. Corey, 1996 .

Natural and synthetic saponin adjuvant QS-21 for vaccines against cancer

P. Livingston, D. Gin, J. Gardner, 2011, Expert review of vaccines.

Chemical glycosylation in the synthesis of glycoconjugate antitumour vaccines

D. Gin, Danica P. Galonić, 2007, Nature.

Quillaja saponin variants with central glycosidic linkage modifications exhibit distinct conformations and adjuvant activities

Derek S. Tan, J. Jiménez-Barbero, William E Walkowicz, 2016, Chemical science.

Design, synthesis, and immunologic evaluation of vaccine adjuvant conjugates based on QS-21 and tucaresol.

Derek S. Tan, P. Livingston, D. Gin, 2014, Bioorganic & medicinal chemistry.

Synthesis and preclinical evaluation of QS-21 variants leading to simplified vaccine adjuvants and mechanistic probes.

M. Adams, P. Livingston, D. Gin, 2012, Journal of the American Chemical Society.

A high-throughput scintillation proximity-based assay for human DNA ligase IV.

A. Tomkinson, D. Scheinberg, David Shum, 2012, Assay and drug development technologies.

Synthesis of readily modifiable cyclodextrin analogues via cyclodimerization of an alkynyl-azido trisaccharide.

D. Gin, Mary S. Gin, Kyle D. Bodine, 2004, Journal of the American Chemical Society.

Synthesis of antiproliferative Cephalotaxus esters and their evaluation against several human hematopoietic and solid tumor cell lines: uncovering differential susceptibilities to multidrug resistance.

C. Antczak, Matthew T. Epperson, David Shum, 2008, Chemistry.

A New C(1)-Auxiliary for Anomeric Stereocontrol in the Synthesis of α-Sialyl Glycosides

D. Gin, J. Haberman, 2001 .

Stereoselective synthesis of 2-hydroxy-alpha-mannopyranosides from glucal donors.

D. Gin, J. Y. Kim, V. Di Bussolo, 2001, Organic letters.

Supplementary Information For: Cell-selective Labeling with Amino Acid Precursors for Proteomic Studies of Multicellular Environments Supplementary Figures 2

Martin L. Miller, Konstantinos J. Mavrakis, C. Sander, 2022 .

Saponin QS-21 adjuvants in cancer vaccines

P. Livingston, D. Gin, J. Gardner, 2011 .

Rapid assembly of the doubly-branched pentasaccharide domain of the immunoadjuvant jujuboside A via convergent B(C6F5)3-catalyzed glycosylation of sterically-hindered precursors.

Derek S. Tan, D. Gin, Rashad R. Karimov, 2017, Chemical communications.

Versatile strategy for the divergent synthesis of linear oligosaccharide domain variants of Quillaja saponin vaccine adjuvants.

Derek S. Tan, D. Gin, Alberto Fernández-Tejada, 2015, Chemical communications.

Development of a minimal saponin vaccine adjuvant based on QS-21

Derek S. Tan, Jason S. Lewis, N. Pillarsetty, 2014, Nature chemistry.

Asymmetric synthetic access to the hetisine alkaloids: total synthesis of (+)-nominine.

D. Gin, K. Peese, 2008, Chemistry.

Enhancing Immunogenicity of Cancer Vaccines: QS-21 as an Immune Adjuvant.

S. Slovin, D. Gin, 2011, Current drug therapy.

Design and synthesis of potent Quillaja saponin vaccine adjuvants.

M. Adams, P. Livingston, D. Gin, 2010, Journal of the American Chemical Society.

DEHYDRATIVE GLYCOSYLATION WITH 1-HYDROXY DONORS

D. Gin, 2002 .

Chemoselective Iterative Dehydrative Glycosylation.

Hien M. Nguyen, D. Gin, Jennifer L. Poole, 2001, Angewandte Chemie.

Development of Improved Vaccine Adjuvants Based on the Saponin Natural Product QS-21 through Chemical Synthesis

Derek S. Tan, D. Gin, Alberto Fernández-Tejada, 2016, Accounts of chemical research.

Synthesis of the trisaccharide portion of the immunologic adjuvant QS-21A via sulfonium-mediated oxidative and dehydrative glycosylation.

D. Gin, Y. J. Kim, 2001, Organic letters.

1,3,5-Trimethylbenzene(mesitylene) adducts with selected tin(II) compounds: the syntheses of Sn(SO3F)2•C9H12 and Sn(SbF6)2•2C9H12

F. Aubke, D. Gin, J. R. Sams, 1990 .

Total synthesis, relay synthesis, and structural confirmation of the C18-norditerpenoid alkaloid neofinaconitine.

Derek S. Tan, D. Gin, L. U. Nordstrøm, 2013, Journal of the American Chemical Society.

Annulation of thioimidates and vinyl carbodiimides to prepare 2-aminopyrimidines, competent nucleophiles for intramolecular alkyne hydroamination. Synthesis of (-)-crambidine.

N. Ide, D. Gin, S. Durón, 2010, Journal of the American Chemical Society.

Probing the mechanism of sulfoxide-catalyzed hemiacetal activation in dehydrative glycosylation.

D. Gin, T. Boebel, 2005, The Journal of organic chemistry.

Sulfoxide covalent catalysis: application to glycosidic bond formation.

D. Gin, T. Boebel, 2003, Angewandte Chemie.

Dehydrative Glycosylation with Activated Diphenyl Sulfonium Reagents. Scope, Mode of C(1)-Hemiacetal Activation, and Detection of Reactive Glycosyl Intermediates

D. Gin, Brian A. Garcia and, 2000 .

Direct Glycosylations with 1-Hydroxy Glycosyl Donors using Trifluoromethanesulfonic Anhydride and Diphenyl Sulfoxide

D. Gin, Jennifer L. Poole, B. Garcia, 1997 .

Direct Oxidative Glycosylations with Glycal Donors

D. Gin, V. D. Bussolo, Yong-jae Kim, 1998 .

Total Synthesis of (+)‐Pyrenolide D

Kenneth M. Engstrom, D. Gin, Mario R. Mendoza, 2001 .

C2-amidoglycosylation. Scope and mechanism of nitrogen transfer.

D. Gin, Jing Liu, 2002, Journal of the American Chemical Society.

Acetamidoglycosylation with Glycal Donors: A One‐Pot Glycosidic Coupling with Direct Installation of the Natural C(2)‐N‐Acetylamino Functionality

D. Gin, Jing Liu, V. D. Bussolo, 2000 .

C2-Acetamidomannosylation. Synthesis of 2-N-acetylamino-2-deoxy-α-d-mannopyranosides with glucal donors

D. Gin, Jing Liu, V. D. Bussolo, 2003 .

Ring-opening of aziridine-2-carboxamides with carbohydrate C1-O-nucleophiles. Stereoselective preparation of alpha- and beta-O-glycosyl serine conjugates.

D. Gin, Daniel A Ryan, 2008, Journal of the American Chemical Society.

Sulfide-mediated dehydrative glycosylation.

Hien M. Nguyen, H. M. Nguyen, D. Gin, 2001, Journal of the American Chemical Society.

Synthesis and structure verification of the vaccine adjuvant QS-7-Api. Synthetic access to homogeneous Quillaja saponaria immunostimulants.

M. Adams, K. Deng, D. Gin, 2008, Journal of the American Chemical Society.

A convergent enantioselective synthesis of the tetrahydroisoquinoline unit in the spiro ring of ecteinascidin 743

E. Corey, D. Gin, 1996 .

5-(Methylthio)tetrazoles as Versatile Synthons in the Stereoselective Synthesis of Polycyclic Pyrazolines via Photoinduced Intramolecular Nitrile Imine-Alkene 1,3-Dipolar Cycloaddition.

Derek S. Tan, D. Gin, D. Pla, 2014, Chemical science.

Application of an intramolecular dipolar cycloaddition to an asymmetric synthesis of the fully oxygenated tricyclic core of the stemofoline alkaloids.

Matthew T. Epperson, D. Gin, Ryan J. Carra, 2008, Tetrahedron.

Enantiospecific synthesis of the bridged pyrrolizidine core of asparagamine A: dipolar cycloadditions of azomethine ylides derived from the sulfonylation of vinylogous amides.

Matthew T. Epperson, D. Gin, 2002, Angewandte Chemie.

Total synthesis of (+)-batzelladine A and (-)-batzelladine D via [4 + 2]-annulation of vinyl carbodiimides with N-alkyl imines.

D. Gin, S. Durón, Kendall Day, 2006, Journal of the American Chemical Society.

Synthetic Studies of the Tunicamycin Antibiotics. Preparation of (+)-Tunicaminyluracil, (+)-Tunicamycin-V, and 5'-epi-Tunicamycin-V

D. Rogers, A. Myers, D. Gin, 1994 .

A convergent synthetic route to the tunicamycin antibiotics. Synthesis of (+)-tunicamycin V

D. Rogers, A. Myers, D. Gin, 1993 .

Silicon-mediated reductive coupling of aldehydes and allylic alcohols. A stereoselective synthesis of tunicaminyluracil

A. Myers, D. Gin, K. Widdowson, 1991 .

Strain-release rearrangement of N-vinyl-2-arylaziridines. Total synthesis of the anti-leukemia alkaloid (-)-deoxyharringtonine.

D. Gin, J. D. Eckelbarger, J. Wilmot, 2006, Journal of the American Chemical Society.

Synthetic access to the chlorocyclopentane cores of the proposed original and revised structures of palau'amine.

D. Gin, Michael S. Bultman, Jun Ma, 2008, Angewandte Chemie.

Diastereoselective [4+2] annulation of vinyl carbodiimides with N-alkyl imines. Asymmetric synthetic access to the batzelladine alkaloids.

D. Gin, S. Durón, M. Arnold, 2005, Journal of the American Chemical Society.

Synthesis and determination of absolute configuration of the bicyclic guanidine core of batzelladine A.

D. Gin, S. Durón, 2001, Organic letters.

Synthesis of the hexacyclic triterpene core of the jujuboside saponins via tandem Wolff rearrangement-intramolecular ketene hetero-Diels-Alder reaction.

Derek S. Tan, Derek S Tan, D. Gin, 2018, Tetrahedron.

Aziridine-2-carboxylic acid-containing peptides: application to solution- and solid-phase convergent site-selective peptide modification.

Nathan D. Ide, N. Ide, W. A. van der Donk, 2005, Journal of the American Chemical Society.

C2-acyloxyglycosylation with glycal donors.

D. Gin, Y. J. Kim, L. Shi, 2001, Journal of the American Chemical Society.

Direct Oxidative Glycosylations with Glycal Donors.

D. Gin, V. D. Bussolo, Yong-jae Kim, 1999 .

Highly convergent synthesis of C3- or C2-symmetric carbohydrate macrocycles.

D. Gin, Mary S. Gin, Kyle D. Bodine, 2005, Organic letters.

Digoxin and its derivatives suppress TH17 cell differentiation by antagonizing RORγt activity

Dan R. Littman, Maria Ciofani, Fabio R. Santori, 2011, Nature.

Oligosaccharide-peptide ligation of glycosyl thiolates with dehydropeptides: synthesis of S-linked mucin-related glycopeptide conjugates.

W. A. van der Donk, D. Gin, Danica P. Galonić, 2003, Chemistry.

Glycoside Synthesis from 1‐Oxygen Substituted Glycosyl Donors: Sections 3.1 and 3.2

R. Schmidt, D. Gin, Xiangming Zhu, 2008 .

Dehydrative Glycosylation with Activated Diphenyl Sulfonium Reagents. Scope, Mode of C(1)-Hemiacetal Activation, and Detection of Reactive Glycosyl Intermediates.

D. Gin, B. Garcia, 2000 .

Dehydrative sialylation with C2-hemiketal sialyl donors.

D. Gin, J. Haberman, 2003, Organic letters.

Preclinical evaluation of the synthetic adjuvant SQS-21 and its constituent isomeric saponins.

M. Adams, K. Deng, G. Ragupathi, 2010, Vaccine.

Site-selective conjugation of thiols with aziridine-2-carboxylic acid-containing peptides.

W. A. van der Donk, D. Gin, Danica P. Galonić, 2004, Journal of the American Chemical Society.

Synthesis of the potent immunostimulatory adjuvant QS-21A.

Pengfei Wang, D. Gin, Bridget D. Rohde, 2005, Journal of the American Chemical Society.

Synthesis of QS-21-xylose: establishment of the immunopotentiating activity of synthetic QS-21 adjuvant with a melanoma vaccine.

M. Adams, K. Deng, P. Livingston, 2008, Angewandte Chemie.

Semisynthesis of Analogues of the Saponin Immunoadjuvant QS-21.

Derek S. Tan, D. Gin, William E. Walkowicz, 2017, Methods in molecular biology.

Synthetic studies of complex immunostimulants from Quillaja saponaria: synthesis of the potent clinical immunoadjuvant QS-21Aapi.

Pengfei Wang, D. Gin, J. Derryberry, 2006, Journal of the American Chemical Society.

Cell-selective labeling with amino acid precursors for proteomic studies of multicellular environments

Martin L. Miller, Konstantinos J. Mavrakis, C. Sander, 2013, Nature Methods.

Non-Natural and Photo-Reactive Amino Acids as Biochemical Probes of Immune Function

D. Scheinberg, M. Gómez‐Nuñez, T. Dao, 2008, PloS one.

A novel high throughput 1536-well Notch1 γ -secretase AlphaLISA assay.

David Shum, B. Bhinder, Hakim Djaballah, 2013, Combinatorial chemistry & high throughput screening.

Highly convergent synthesis of C3- or C2-symmetric carbohydrate macrocycles.

D. Gin, Mary S. Gin, Kyle D. Bodine, 2005, Organic letters.

Efficient synthetic access to the hetisine C20-diterpenoid alkaloids. A concise synthesis of nominine via oxidoisoquinolinium-1,3-dipolar and dienamine-Diels-Alder cycloadditions.

D. Gin, K. Peese, 2006, Journal of the American Chemical Society.

Enantioselective approach to the hetisine alkaloids. Synthesis of the 3-methyl-1-aza-tricyclo[5.2.1.0(3,8)]decane core via intramolecular dipolar cycloaddition.

D. Gin, K. Peese, 2005, Organic letters.

Cell-selective labeling with amino acid precursors for proteomic studies of multicellular environments

Martin L. Miller, Konstantinos J. Mavrakis, C. Sander, 2013, Nature Methods.