J. Ruan

发表

Development and preclinical studies of broad-spectrum anti-HIV agent (3'R,4'R)-3-cyanomethyl-4-methyl-3',4'-di-O-(S)-camphanoyl-(+)-cis-khellactone (3-cyanomethyl-4-methyl-DCK).

Hong Lu, Shibo Jiang, Keduo Qian, 2008, Journal of medicinal chemistry.

Determination of 4-dimethylaminophenol concentrations in dog blood using LC-ESI/MS/MS combined with precolumn derivatization.

Xiaomei Zhuang, J. Ruan, M. Yuan, 2008, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

Simultaneous determination of thirteen flavonoids from Xiaobuxin-Tang extract using high-performance liquid chromatography coupled with electrospray ionization mass spectrometry.

L. Zang, Sujun Wang, G. Wang, 2015, Journal of pharmaceutical and biomedical analysis.

Simultaneous quantification of chlorogenic acid and caffeic acid in rat plasma after an intravenous administration of mailuoning injection using liquid chromatography/mass spectrometry.

J. Ruan, Jing Li, Z. Zhang, 2006, Rapid communications in mass spectrometry : RCM.

P-glycoprotein is responsible for the poor intestinal absorption and low toxicity of oral aconitine: in vitro, in situ, in vivo and in silico studies.

Liang Xu, Fei Liu, Cuiping Yang, 2013, Toxicology and applied pharmacology.

Transcellular transport of aconitine across human intestinal Caco-2 cells.

Fei Liu, Cuiping Yang, Zheng Li, 2013, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.

Pharmacological profiles of an anticholinergic agent, phencynonate hydrochloride, and its optical isomers

B. Zhong, J. Ruan, Ke-liang Liu, 2005, Acta Pharmacologica Sinica.

Gas Chromatographic–Mass Spectrometric Method for Quantitation of Trimethylsilyl Derivatives of Nerve Agent Degradation Products in Human Plasma, Using Strong Anion–Exchange Solid-Phase Extraction

Jianwei Xie, Jianwei Xie, J. Ruan, 2005 .

Metabolism of novel anti-HIV agent 3-cyanomethyl-4-methyl-DCK by human liver microsomes and recombinant CYP enzymes

Lan Xie, Xiaomei Zhuang, J. Ruan, 2011, Acta Pharmacologica Sinica.

Metabolic stability of human parathyroid hormone peptide hPTH (1–34) in rat tissue homogenates: kinetics and products of proteolytic degradation

M. Xue, Zhen-qing Zhang, J. Ruan, 2010, Amino Acids.

Degradation of salmon calcitonin in rat kidney and liver homogenates.

Zhen-qing Zhang, J. Ruan, Ke-liang Liu, 2008, Die Pharmazie.

Simultaneous determination of harpagoside and cinnamic acid in rat plasma by liquid chromatography electrospray ionization mass spectrometry and its application to pharmacokinetic studies.

Zhen-qing Zhang, J. Ruan, Yan-hong Zhao, 2008, Biomedical chromatography : BMC.

Anticonvulsant effects of phencynonate hydrochloride and other anticholinergic drugs in soman poisoning: neurochemical mechanisms.

Wen-xia Zhou, J. Ruan, Ke-liang Liu, 2005, Life sciences.

Structural elucidation of in vivo metabolites of penehyclidine in rats by the method of liquid chromatography-mass spectrometry, gas chromatography-mass spectrometry and isotope ion cluster.

Y. Liu, Xiao-rong Li, M. Xue, 2008, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

Comparative pharmacokinetics and distribution kinetics in brain of phencynonate enantiomers in rats.

Y. Liu, M. Xue, J. Ruan, 2008, International journal of pharmaceutics.

Liquid chromatography-tandem electrospray mass spectrometry method for determination of serial chiral novel anticholinergic compounds of phencynonate in rat plasma.

Jinglai Li, Sujun Wang, Zhen-qing Zhang, 2007, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

Effects of pretreatment with 8018 on the toxicokinetics of soman in rabbits and distribution in mice.

Wei-dong Yu, Zhen-qing Zhang, J. Ruan, 2003, Life sciences.

Liquid chromatography-tandem mass spectrometry method for determination of phencynonate in rat blood and urine.

M. Xue, Zhen-qing Zhang, J. Ruan, 2005, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

Comparative study on pharmacological effects of DM-phencynonate hydrochloride and its optical isomers

B. Zhong, J. Ruan, Ke-liang Liu, 2005, Acta Pharmacologica Sinica.

Structural elucidation of in vivo metabolites of phencynonate and its analogue thiencynonate in rats by HPLC-ESI-MSn.

Y. Liu, M. Xue, J. Ruan, 2010, Talanta.

Determination of penehyclidine by gas chromatographic-mass spectrometry and its application to pharmacokinetics in humans, rabbits and mice.

M. Xue, Zhen-qing Zhang, J. Ruan, 2006, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

Determination of thiencynonate by liquid chromatographic-mass spectrometry and its application to pharmacokinetics in rats.

Y. Liu, M. Xue, Zhen-qing Zhang, 2006, Journal of pharmaceutical and biomedical analysis.

[Anticonvulsant effect of phencynonate hydrochloride on maximal electroshock seizure and the metrazol seizure threshold test in mice].

Wen-xia Zhou, J. Ruan, Ke-liang Liu, 2005, Yao xue xue bao = Acta pharmaceutica Sinica.

[Identification of the metabolites of penehyclidine hydrochloride raceme in rats by LC-MS/MS and ion cluster].

M. Xue, Jifen Guo, Zhen-qing Zhang, 2002, Yao xue xue bao = Acta pharmaceutica Sinica.

Influence of portal vein and liver artery ligation on the toxicokinetics of soman in rabbits.

Zhen-qing Zhang, J. Ruan, Dongkyo Han, 2002, Toxicology letters.

Screening of traditional Chinese remedies for SARS treatment.

A. Liang, J. Ruan, Zhi-min Wang, 2003, Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica.

Pharmacokinetic properties of albiflorin and paeoniflorin after oral administration of pure compound, Radix Paeoniae alba extract and Danggui-Shaoyao-San extract to rats

M. Wang, L. Kang, He-shui Yu, 2011, Journal of Asian natural products research.

[Research progress of enhancing quantitative sensitivity by using LC-MS(n) with derivatization method in bio-matrices].

Zhen-qing Zhang, J. Ruan, Li-li Xu, 2011, Yao xue xue bao = Acta pharmaceutica Sinica.

Simultaneous determination of thienorphine and its active metabolite thienorphine glucuronide in rat plasma by liquid chromatography-tandem mass spectrometry and its application to pharmacokinetic studies.

Zhen-qing Zhang, J. Ruan, Z. Gong, 2007, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

Quantification of peramivir (a novel anti-influenza drug) in human plasma by hydrophilic interaction chromatography/tandem mass spectrometry.

Xinzhong Zhang, Zhen-qing Zhang, J. Ruan, 2009, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

Quantification of peramivir in dog plasma by liquid chromatography/tandem mass spectrometry employing precolumn derivatization.

Juan Wang, X. Li, Zhen-qing Zhang, 2014, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

Effects of pretreatment with verapamil on the toxicokinetics of soman in rabbits and distribution in mouse brain and diaphragm.

Wei-dong Yu, Zhen-qing Zhang, J. Ruan, 2003, Toxicology letters.

Influence of nimodipine on elimination of soman in rabbit blood and distribution of [3H]soman in mice.

Zhen-qing Zhang, J. Ruan, Jin-Tong Li, 2002, Acta pharmacologica Sinica.

Pharmacokinetic properties of albiflorin and paeoniflorin after oral administration of pure compound, Radix Paeoniae alba extract and Danggui-Shaoyao-San extract to rats

M. Wang, L. Kang, He-shui Yu, 2011, Journal of Asian natural products research.