Terrence R Burke

发表

Synthesis of a C-terminally biotinylated macrocyclic peptide mimetic exhibiting high Grb2 SH2 domain-binding affinity.

Dajun Yang, Robert J Fisher, Zhen-Dan Shi, 2005, Bioorganic & medicinal chemistry.

Phosphotyrosyl mimetics in the development of signal transduction inhibitors.

T. Burke, Terrence R Burke, Kyeong Lee, 2003, Accounts of chemical research.

Macrocyclization in the design of non-phosphorus-containing Grb2 SH2 domain-binding ligands.

Dajun Yang, Robert J Fisher, Zhen-Dan Shi, 2004, Journal of medicinal chemistry.

Metal-dependent inhibition of HIV-1 integrase.

Dirk Strumberg, Marc C Nicklaus, Yves Pommier, 2002, Journal of medicinal chemistry.

Macrocyclization in the design of Grb2 SH2 domain-binding ligands exhibiting high potency in whole-cell systems.

Dajun Yang, Manchao Zhang, Dajun Yang, 2003, Journal of medicinal chemistry.

Examination of phosphoryl-mimicking functionalities within a macrocyclic Grb2 SH2 domain-binding platform.

Robert J Fisher, Zhen-Dan Shi, Sang-Uk Kang, 2005, Journal of medicinal chemistry.

A novel macrocyclic tetrapeptide mimetic that exhibits low-picomolar Grb2 SH2 domain-binding affinity.

Dajun Yang, Robert J Fisher, Zhen-Dan Shi, 2003, Biochemical and biophysical research communications.

Structure activity of 3-aryl-1,3-diketo-containing compounds as HIV-1 integrase inhibitors.

Yun Tang, Yves Pommier, Nouri Neamati, 2002, Journal of medicinal chemistry.

Evaluation of macrocyclic Grb2 SH2 domain-binding peptide mimetics prepared by ring-closing metathesis of C-terminal allylglycines with an N-terminal beta-vinyl-substituted phosphotyrosyl mimetic.

Marc C Nicklaus, Shinya Oishi, Robert J Fisher, 2005, Bioorganic & medicinal chemistry.

Design and synthesis of 4-(alpha-hydroxymalonyl)phenylalanine as a new phosphotyrosyl mimetic and its use in growth factor receptor bound 2 src-homology 2 (Grb2 SH2) domain-binding peptides.

Dajun Yang, Robert J Fisher, Sang-Uk Kang, 2005, Journal of medicinal chemistry.

Metal-dependent inhibition of HIV-1 integrase by beta-diketo acids and resistance of the soluble double-mutant (F185K/C280S).

Marc C Nicklaus, Yves Pommier, Y. Pommier, 2003, Molecular pharmacology.

Discovery of a small-molecule HIV-1 integrase inhibitor-binding site.

Myriam Witvrouw, Christoph H Borchers, Laith Q Al-Mawsawi, 2006, Proceedings of the National Academy of Sciences of the United States of America.

Crystal structures of a high-affinity macrocyclic peptide mimetic in complex with the Grb2 SH2 domain.

Zhen-Dan Shi, T. Burke, D. Waugh, 2005, Journal of molecular biology.

Utilization of a Common Pathway for the Synthesis of High Affinity Macrocyclic Grb2 SH2 Domain‐Binding Peptide Mimetics That Differ in the Configuration at One Ring Junction

Marc C Nicklaus, Robert J Fisher, Zhen-Dan Shi, 2005, Chemistry & biodiversity.

Design and synthesis of conformationally constrained Grb2 SH2 domain binding peptides employing alpha-methylphenylalanyl based phosphotyrosyl mimetics.

Marc C Nicklaus, Shinya Oishi, Robert J Fisher, 2005, Journal of medicinal chemistry.