P. Henning

发表

Retinoid Receptors in Bone and Their Role in Bone Remodeling

U. Lerner, P. Henning, H. Conaway, 2015, Front. Endocrinol..

Vitamin a metabolism, action, and role in skeletal homeostasis.

U. Lerner, P. Henning, H. Conaway, 2013, Endocrine reviews.

NOTUM inhibition increases endocortical bone formation and bone strength

F. Mseeh, S. Movérare-Skrtic, C. Ohlsson, 2019, Bone Research.

Immunoglobulin G complexes without sialic acids enhance osteoclastogenesis but do not affect arthritis‐mediated bone loss

M. Lagerquist, U. Lerner, A. Westerlund, 2020, Scandinavian journal of immunology.

Osteoblast-derived NOTUM reduces cortical bone mass in mice and the NOTUM locus is associated with bone mineral density in humans

F. Rivadeneira, S. Movérare-Skrtic, C. Ohlsson, 2019, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Inducible Wnt16 inactivation: WNT16 regulates cortical bone thickness in adult mice

K. Sjögren, M. Lagerquist, S. Movérare-Skrtic, 2018, The Journal of endocrinology.

SNX10 gene mutation leading to osteopetrosis with dysfunctional osteoclasts

Therese G. Kellgren, A. Ameur, G. Hallmans, 2017, Scientific Reports.

The bone-sparing effects of estrogen and WNT16 are independent of each other

J. Gustafsson, K. Sjögren, M. Lagerquist, 2015, Proceedings of the National Academy of Sciences.

Activation of Shc1 Allows Oncostatin M to Induce RANKL and Osteoclast Formation More Effectively Than Leukemia Inhibitory Factor

U. Lerner, E. Persson, P. Henning, 2019, Front. Immunol..

Porcupine inhibitors impair trabecular and cortical bone mass and strength in mice

S. Movérare-Skrtic, C. Ohlsson, J. Tuukkanen, 2018, Journal of Endocrinology.

Retinoids Stimulate Periosteal Bone Resorption by Enhancing the Protein RANKL, a Response Inhibited by Monomeric Glucocorticoid Receptor*

O. Svensson, J. Tuckermann, U. Lerner, 2011, The Journal of Biological Chemistry.

Mendelian Randomization Analysis Reveals a Causal Influence of Circulating Sclerostin Levels on Bone Mineral Density and Fractures

E. Zeggini, S. Reppe, K. Gautvik, 2019, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Mendelian Randomization Analysis Reveals a Causal Influence of Circulating Sclerostin Levels on Bone Mineral Density and Fractures

E. Zeggini, S. Reppe, K. Gautvik, 2018, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Genome-wide mapping identifies beta-1,4-N-acetyl-galactosaminyl-transferase as a novel determinant of sclerostin levels and bone mineral density

E. Zeggini, S. Reppe, K. Gautvik, 2018, bioRxiv.

WNT16 overexpression partly protects against glucocorticoid-induced bone loss.

S. Movérare-Skrtic, M. Poutanen, C. Ohlsson, 2018, American journal of physiology. Endocrinology and metabolism.

Osteoblast-derived WNT16 represses osteoclastogenesis and prevents cortical bone fragility fractures

R. Baron, K. Sjögren, S. Movérare-Skrtic, 2014, Nature Medicine.

Estradiol and RSPO3 regulate vertebral trabecular bone mass independent of each other

S. Movérare-Skrtic, C. Ohlsson, J. Tuckermann, 2022, American journal of physiology. Endocrinology and metabolism.

Arginine site 264 in murine estrogen receptor alpha is dispensable for the regulation of the skeleton.

M. Lagerquist, S. Movérare-Skrtic, C. Ohlsson, 2020, American journal of physiology. Endocrinology and metabolism.

The role of membrane ERα signaling in bone and other major estrogen responsive tissues

J. Gustafsson, M. Lagerquist, S. Movérare-Skrtic, 2016, Scientific Reports.

Increased bone mass in a mouse model with low fat mass.

K. Sjögren, M. Lagerquist, C. Ohlsson, 2018, American journal of physiology. Endocrinology and metabolism.

Glucocorticoids employ the monomeric glucocorticoid receptor to potentiate vitamin D3 and parathyroid hormone–induced osteoclastogenesis

J. Tuckermann, U. Lerner, P. Henning, 2019, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Activation of dimeric glucocorticoid receptors in osteoclast progenitors potentiates RANKL induced mature osteoclast bone resorbing activity.

J. Tuckermann, U. Lerner, P. Henning, 2016, Bone.

Pasteurized Akkermansia muciniphila protects from fat mass gain but not from bone loss

W. D. de Vos, K. Sjögren, C. Ohlsson, 2020, American journal of physiology. Endocrinology and metabolism.

A tissue-specific role of membrane-initiated ERα signaling for the effects of SERMs

M. Lagerquist, S. Movérare-Skrtic, C. Ohlsson, 2022, The Journal of endocrinology.

Osteocyte- and late Osteoblast-derived NOTUM Reduces Cortical Bone Mass in Mice.

S. Movérare-Skrtic, C. Ohlsson, J. Tuukkanen, 2021, American journal of physiology. Endocrinology and metabolism.

WNT16 is Robustly Increased by Oncostatin M in Mouse Calvarial Osteoblasts and Acts as a Negative Feedback Regulator of Osteoclast Formation Induced by Oncostatin M

S. Movérare-Skrtic, C. Ohlsson, U. Lerner, 2021, Journal of inflammation research.

SUN-744 Phosphorylation Site S122 in Estrogen Receptor α Has a Tissue-Dependent Role in Female Mice

P. Chambon, M. Lagerquist, S. Movérare-Skrtic, 2020, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Membrane estrogen receptor α is essential for estrogen signaling in the male skeleton.

M. Lagerquist, S. Movérare-Skrtic, C. Ohlsson, 2018, The Journal of endocrinology.

Osteoclast progenitor cells present in significant amounts in mouse calvarial osteoblast isolations and osteoclastogenesis increased by BMP-2.

U. Lerner, C. Lindholm, P. Henning, 2013, Bone.

Activation of Liver X Receptor (LXR) Inhibits Receptor Activator of Nuclear Factor κB Ligand (RANKL)-induced Osteoclast Differentiation in an LXRβ-dependent Mechanism*

J. Gustafsson, U. Lerner, P. Henning, 2011, The Journal of Biological Chemistry.

Effects of retinoids on physiologic and inflammatory osteoclastogenesis in vitro

U. Lerner, A. Westerlund, P. Henning, 2018, Journal of leukocyte biology.

Reduction of Mature B Cells and Immunoglobulins Results in Increased Trabecular Bone

M. Lagerquist, C. Corciulo, P. Henning, 2022, JBMR plus.

TLR5, a novel mediator of innate immunity‐induced osteoclastogenesis and bone loss

U. Lerner, C. Lindholm, P. Henning, 2015, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Antibiotics with Interleukin-15 Inhibition Reduce Joint Inflammation and Bone Erosions but Not Cartilage Destruction in Staphylococcus aureus-Induced Arthritis

C. Ohlsson, I. McInnes, U. Lerner, 2018, Infection and Immunity.

Cysteine proteinase inhibitors regulate human and mouse osteoclastogenesis by interfering with RANK signaling

M. Abrahamson, U. Lerner, F. Kasprzykowski, 2013, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

The gut microbiota regulates bone mass in mice

V. Tremaroli, F. Bäckhed, K. Sjögren, 2012, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

RSPO3 is important for trabecular bone and fracture risk in mice and humans

T. Lehtimäki, J. Richards, S. Movérare-Skrtic, 2021, Nature Communications.

An ARHGAP25 variant links aberrant Rac1 function to early‐onset skeletal fragility

F. Rivadeneira, O. Mäkitie, C. Medina-Gomez, 2021, JBMR plus.

The androgen receptor is required for maintenance of bone mass in adult male mice

K. Sjögren, S. Movérare-Skrtic, C. Ohlsson, 2019, Molecular and Cellular Endocrinology.

The effects of estradiol are modulated in a tissue-specific manner in mice with inducible inactivation of ERα after sexual maturation.

J. Gustafsson, K. Sjögren, M. Lagerquist, 2020, American journal of physiology. Endocrinology and metabolism.

Comparisons between the effects of calcitonin receptor‐stimulating peptide and intermedin and other peptides in the calcitonin family on bone resorption and osteoclastogenesis

U. Lerner, P. Henning, S. Granholm, 2011, Journal of cellular biochemistry.

Osteoporosis and skeletal dysplasia caused by pathogenic variants in SGMS2

O. Mäkitie, J. Carey, P. Bayrak-Toydemir, 2019, JCI insight.

Stimulation of Osteoclast Formation by Oncostatin M and the Role of WNT16 as a Negative Feedback Regulator

U. Lerner, P. Henning, P. D. de Souza, 2022, International journal of molecular sciences.

Acute fat loss does not affect bone mass

K. Sjögren, M. Lagerquist, C. Ohlsson, 2021, Scientific Reports.

Porphyromonas gingivalis Stimulates Bone Resorption by Enhancing RANKL (Receptor Activator of NF-κB Ligand) through Activation of Toll-like Receptor 2 in Osteoblasts*

U. Lerner, C. Lindholm, P. Henning, 2015, The Journal of Biological Chemistry.

SNX10 gene mutation leading to osteopetrosis with dysfunctional osteoclasts

Therese G. Kellgren, A. Ameur, G. Hallmans, 2017, Scientific Reports.

Estrogen receptor-α is required for the osteogenic response to mechanical loading in a ligand-independent manner involving its activation function 1 but not 2

Claes Ohlsson, Pierre Chambon, L. Lanyon, 2013, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

ERα expression in T lymphocytes is dispensable for estrogenic effects in bone

J. Gustafsson, K. Sjögren, M. Lagerquist, 2018, The Journal of endocrinology.

B4GALNT3 regulates glycosylation of sclerostin and bone mass.

M. Lagerquist, S. Movérare-Skrtic, C. Ohlsson, 2023, EBioMedicine.

Phosphorylation of S122 in ERα is important for the skeletal response to estrogen treatment in male mice

K. Sjögren, M. Lagerquist, S. Movérare-Skrtic, 2022, Scientific Reports.

Vitamin A decreases the anabolic bone response to mechanical loading by suppressing bone formation

Furqan A. Shah, S. Windahl, U. Lerner, 2019, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Membrane estrogen receptor α signaling modulates the sensitivity to estradiol treatment in a dose- and tissue- dependent manner

M. Lagerquist, S. Movérare-Skrtic, C. Ohlsson, 2023, Scientific reports.

Bazedoxifene does not share estrogens effects on IgG sialylation

P. Henning, H. Carlsten, C. Engdahl, 2023, PloS one.