T. Cawston

发表

Human nasal cartilage responds to oncostatin M in combination with interleukin 1 or tumour necrosis factor α by the release of collagen fragments via collagenases

A. Hollander, S. Dickinson, A. Rowan, 2005, Annals of the rheumatic diseases.

Interleukin 13 blocks the release of collagen from bovine nasal cartilage treated with proinflammatory cytokines

A. Rowan, T. Cawston, C. Cleaver, 2001, Annals of the rheumatic diseases.

The role of oncostatin M in animal and human connective tissue collagen turnover and its localization within the rheumatoid joint.

M. Goldring, I. Clark, A. Rowan, 1998, Arthritis and rheumatism.

Oncostatin M in combination with tumor necrosis factor alpha induces cartilage damage and matrix metalloproteinase expression in vitro and in vivo.

A. Rowan, C. Richards, T. Cawston, 2003, Arthritis and rheumatism.

Development of a novel 2D proteomics approach for the identification of proteins secreted by primary chondrocytes after stimulation by IL-1 and oncostatin M.

R. Wait, J. Saklatvala, A. Rowan, 2006, Rheumatology.

Oncostatin M in combination with tumour necrosis factor α induces a chondrocyte membrane associated aggrecanase that is distinct from ADAMTS aggrecanase-1 or -2

A. Rowan, D. Young, N. Mckie, 2005, Annals of the rheumatic diseases.

The modulation of matrix metalloproteinase and ADAM gene expression in human chondrocytes by interleukin-1 and oncostatin M: a time-course study using real-time quantitative reverse transcription-polymerase chain reaction.

D. Edwards, I. Clark, A. Rowan, 2002, Arthritis and rheumatism.

Insulin-like growth factor 1 blocks collagen release and down regulates matrix metalloproteinase-1, -3, -8, and -13 mRNA expression in bovine nasal cartilage stimulated with oncostatin M in combination with interleukin 1 (cid:225)

A. Rowan, T. Cawston, W. Hui, 2022 .

Synergistic effects of glycoprotein 130 binding cytokines in combination with interleukin-1 on cartilage collagen breakdown.

J. Heath, A. Vernallis, A. Rowan, 2001, Arthritis and rheumatism.

Matrix metalloproteinases and TIMPs: properties and implications for the treatment of chronic obstructive pulmonary disease.

A. Rowan, T. Cawston, S. Elliott, 2001, Novartis Foundation symposium.

Retinoic acid combines with interleukin‐1 to promote the degradation of collagen from bovine nasal cartilage: Matrix metalloproteinases‐1 and ‐13 are involved in cartilage collagen breakdown

A. Rowan, T. Cawston, W. Shingleton, 2000, Journal of cellular biochemistry.

Modulation of the expression of matrix metalloproteinase and tissue inhibitors of metalloproteinases by TGF-beta1 and IGF-1 in primary human articular and bovine nasal chondrocytes stimulated with TNF-alpha.

A. Rowan, T. Cawston, T. Cawston, 2001, Cytokine.

Esculetin inhibits cartilage resorption induced by interleukin 1α in combination with oncostatin M

A. Rowan, T. Cawston, S. Elliott, 2001, Annals of the rheumatic diseases.

Interleukin 17 induces cartilage collagen breakdown: novel synergistic effects in combination with proinflammatory cytokines

A. Rowan, T. Cawston, T. Cawston, 2002, Annals of the rheumatic diseases.

Matrix metalloproteinase 10 promotion of collagenolysis via procollagenase activation: implications for cartilage degradation in arthritis.

A. Rowan, C. Richards, T. Cawston, 2006, Arthritis and rheumatism.

Inhibition of furin-like enzymes blocks interleukin-1alpha/oncostatin M-stimulated cartilage degradation.

A. Rowan, T. Cawston, S. Elliott, 2003, Arthritis and rheumatism.

96-Well plate assays for measuring collagenase activity using (3)H-acetylated collagen.

A. Rowan, T. Cawston, P. Life, 1999, Analytical biochemistry.

Transforming growth factor beta 1 and insulin-like growth factor 1 block collagen degradation induced by oncostatin M in combination with tumour necrosis factor alpha from bovine cartilage.

A. Rowan, T. Cawston, T. Cawston, 2003, Annals of the rheumatic diseases.

Synergistic induction of matrix metalloproteinase 1 by interleukin-1alpha and oncostatin M in human chondrocytes involves signal transducer and activator of transcription and activator protein 1 transcription factors via a novel mechanism.

J. Rutter, C. Brinckerhoff, A. Rowan, 2001, Arthritis and rheumatism.

The differential responses of human skin and synovial fibroblasts to stanozololin vitro: Production of prostaglandin E2 and matrix metalloproteinases

B. Hazleman, T. Cawston, J. K. Wright, 1992, Agents and Actions.

Transcriptional activity of the human tissue inhibitor of metalloproteinases 1 (TIMP-1) gene in fibroblasts involves elements in the promoter, exon 1 and intron 1.

T. Bech-Hansen, M. Bahr, D. Edwards, 1997, The Biochemical journal.

Interleukin-1 in combination with oncostatin M up-regulates multiple genes in chondrocytes: implications for cartilage destruction and repair.

A. Rowan, C. Richards, I. Wappler, 2006, Arthritis and rheumatism.

Retinoic acid and oncostatin M combine to promote cartilage degradation via matrix metalloproteinase-13 expression in bovine but not human chondrocytes.

X. Xu, A. Rowan, D. Jones, 2006, Rheumatology.

A Computer Simulation Approach to Assessing Therapeutic Intervention Points for the Prevention of Cytokine-Induced Cartilage Breakdown

A. Rowan, T. Cawston, CJ Proctor, 2014, Arthritis & rheumatology.

Evaluation of chondrocyte micromass culture for the study of cartilage degradation

T. Morgan, T. Cawston, X. Xu, 2005, Arthritis Research & Therapy.

Structure of full-length porcine synovial collagenase reveals a C-terminal domain containing a calcium-linked, four-bladed beta-propeller.

B. Hazleman, P. Brick, B. Hazleman, 1995, Structure.

Proteinases and inhibitors.

T. Cawston, T. Cawston, 1995, British medical bulletin.