P. Smith

发表

Dihydropyrancarboxamides related to zanamivir: a new series of inhibitors of influenza virus sialidases. 2. Crystallographic and molecular modeling study of complexes of 4-amino-4H-pyran-6-carboxamides and sialidase from influenza virus types A and B.

N R Taylor, P. Colman, A. Wonacott, 1998, Journal of medicinal chemistry.

Drug design against a shifting target: a structural basis for resistance to inhibitors in a variant of influenza virus neuraminidase.

Paul W Smith, P. Colman, J. Varghese, 1998, Structure.

702. Polypeptides. Part IV. The self-condensation of the esters of some peptides of glycine and proline

P. Smith, H. Rydon, 1956 .

New spiropiperidines as potent and selective non-peptide tachykinin NK2 receptor antagonists.

A. Mcelroy, N. Taylor, J. Pritchard, 1995, Journal of medicinal chemistry.

Sialidase as a target for inhibitors of influenza virus replication.

R. Bethell, P. Smith, 1997, Expert opinion on investigational drugs.

1,4-Dideoxy-1,4-imino-D-mannitol inhibits glycoprotein processing and mannosidase.

G. Fleet, M. Mitchell, A. Elbein, 1985, Archives of biochemistry and biophysics.

The enol content and acidity of cyclopentanone, cyclohexanone, and acetone in aqueous solution

R. Bell, P. Smith, 1966 .

13C and 1H n.m.r. studies of solid polyolefines

K. J. Packer, R. Harris, P. Smith, 1985 .

Dihydropyrancarboxamides related to zanamivir: a new series of inhibitors of influenza virus sialidases. 1. Discovery, synthesis, biological activity, and structure-activity relationships of 4-guanidino- and 4-amino-4H-pyran-6-carboxamides.

A Merritt, I. D. Starkey, A. Beresford, 1998, Journal of medicinal chemistry.

Synthesis of deoxymannojirimycin fagomine deoxynojirimycin 2-acetamido-1,5-imino-1,2,5-trideoxy-D-mannitol 2-acetamido-1,5-imino-1,2,5-trideoxy-D-glucitol 2S,3R,4R,5R-trihydroxypipecolic acid and 2S,3R,4R,5S-trihydroxypipecolic acid from methyl 3-O-benzyl-2,6-dideoxy-2,6-imino-α-D-mannofuranoside

P. Smith, G. Fleet, L. Fellows, 1987 .

Synthesis of tetrasubstituted bicyclo[3.2.1]octenes as potential inhibitors of influenza virus sialidase.

G. Hardy, R. Bethell, R. Upton, 1999, Bioorganic & medicinal chemistry letters.

Sialidase inhibitors related to zanamivir: synthesis and biological evaluation of 4H-pyran 6-ether and ketone.

R. Bethell, P. Smith, S. Sollis, 1999, Bioorganic & medicinal chemistry letters.

Synthesis and biological activity of novel cephalosporins containing a (Z)-vinyl dimethylphosphonate group.

P. Smith, P. Howes, K. Cobley, 1995, The Journal of antibiotics.

Enantiospecific syntheses of deoxymannojirimycin, fagomine and 2r,5r-dihydroxymethyl-3r,4r-dihydroxypyrrolidine from D-glucose

P. Smith, G. Fleet, 1985 .

500. Ditertiary arsine complexes of octahedral bivalent molybdenum

R. Nyholm, P. Smith, J. Lewis, 1962 .

The Ritter reaction in the synthesis of ortho-fused nitrogen-containing heterocycles

A. Oxford, P. Smith, R. M. Southam, 1980 .

The synthesis from d-xylose of the potent and specific enantiomeric glucosidase inhibitors, 1,4-dideoxy-1,4-imino-d-arabinitol and 1,4-dideoxy-1,4-imin

P. Smith, G. Fleet, 1986 .

Potent competitive inhibition of α-galactosidase and α-glucosidase activity by 1,4-dideoxy-1,4-iminopentitols: syntheses of 1,4-dideoxy-1,4-imino-d-lyxitol and of both enantiomers of 1,4-dideoxy-1,4-iminoarabinitol

S. V. Evans, P. Smith, G. Fleet, 1985 .

Nuclear quadrupole resonance studies of compounds of type AI2MIIICl5(H2O). I. K2FeCl5·H2O*

P. Smith, R. Stoessiger, 1978 .

Enantiospecific syntheses of deoxymannojirimycin, fagomine and 2r,5r-dihydroxymethyl-3r,4r-dihydroxypyrrolidine from D-glucose

P. Smith, G. Fleet, 1985 .

Synthesis of 2R,3S,4R-dihydroxyproline from D-ribonolactone

P. Smith, G. Fleet, K. Prout, 1986 .

Enantiospecific synthesis of swainsonine, (1S, 2R, 8R, 8aR)-1,2,8-trihydroxyoctahydroindolizine, from D-mannose

P. Smith, G. Fleet, M. Gough, 1984 .

S. V. Evans, P. Smith, G. Fleet, 1985 .

Synthesis of Doubly Cross-Linked Cyclic Hexapeptides

D. G. Clarke, P. Smith, S. Carter, 1992 .

Effects of intermetallic bonding and lattice interactions. Electronic spectra of group VIA tervalent halides and complex halides

A. G. Wedd, P. Smith, 1970 .

13C NMR spectroscopic characterization of trimethylol propane ester lubricants

P. Smith, 1992 .

Methyl 2-azido-3-O-benzyl-2-deoxy-α-D-mamnofuranoside as a divergent intermediate for the synthesis of polyhydroxylated piperidines and pyrrolidines: synthesis of 2,5-dideoxy-2,5-imino-D-mannitol [2R,5R-dihydroxymethyl-3R,4R-dihydroxypyrrolidine]

Paul W Smith, P. Smith, G. Fleet, 1987 .

Low molecular weight neurokinin NK2 antagonists

A. Mcelroy, J. Pritchard, R. Hagan, 1993 .

Synthesis of the α-Mannosidase inhibitors swainsonine [(1S, 2R, 8R, 8aR)-1,2,8-trihydroxyoctahydroindolizine] and 1,4-dideoxy-1,4-imino-d-mannitol from mannose

Paul W Smith, P. Smith, G. Fleet, 1987 .

Polypeptides. Part I. The condensation-polymerisation of some polyglycine esters and azides

P. Smith, H. Rydon, 1955 .

The Polarographic Behavior of Chromammines and Chromium(II1) Salts in an Acetate Buffer

P. Smith, J. Friend, 1959 .

Synthesis of a tetrasubstituted bicyclo [2.2.2] octane as a potential inhibitor of influenza virus sialidase.

R. Bethell, S. Lynn, P. Smith, 1999, Bioorganic & medicinal chemistry letters.

Luminescence intensity of tervalent chromium complexes

P. Smith, J. Laver, 1970 .