S. Sollis

发表

Dihydropyrancarboxamides related to zanamivir: a new series of inhibitors of influenza virus sialidases. 2. Crystallographic and molecular modeling study of complexes of 4-amino-4H-pyran-6-carboxamides and sialidase from influenza virus types A and B.

N R Taylor, P. Colman, A. Wonacott, 1998, Journal of medicinal chemistry.

Drug design against a shifting target: a structural basis for resistance to inhibitors in a variant of influenza virus neuraminidase.

Paul W Smith, P. Colman, J. Varghese, 1998, Structure.

Novel inhibitors of influenza sialidase related to GG167 Synthesis of 4-amino and guanidino-4H-pyran-2-carboxylic acid-6-propylamides; selective inhibitors of influenza a virus sialidase

Paul W Smith, R. Bethell, S. Sollis, 1996 .

Novel inhibitors of influenza sialidases related to GG167 structure-activity, crystallographic and Molecular dynamics studies with 4H-pyran-2-carboxylic acid 6-carboxamides

Paul W Smith, P. Colman, J. Varghese, 1996 .

2,5-diketopiperazines as potent, selective, and orally bioavailable oxytocin antagonists. 2. Synthesis, chirality, and pharmacokinetics.

P. Woollard, P. Wyatt, F. Nerozzi, 2005, Journal of medicinal chemistry.

2,5-Diketopiperazines as potent and selective oxytocin antagonists 1: Identification, stereochemistry and initial SAR.

P. Wyatt, F. Nerozzi, A. Szardenings, 2005, Bioorganic & Medicinal Chemistry Letters.

4-Acetylamino-3-(imidazol-1-yl)-benzoic acids as novel inhibitors of influenza sialidase

Paul W Smith, A. Wonacott, N. Taylor, 1999 .

Novel inhibitors of influenza sialidases related to zanamivir. Heterocyclic replacements of the glycerol sidechain

Paul W Smith, N. Taylor, S. Sollis, 1997 .

Synthesis and influenza virus sialidase inhibitory activity of analogues of 4-guanidino-Neu5Ac2en (GG167) with modified 5-substituents

Paul W Smith, M. Itzstein, Wen-Yang Wu, 1996 .

Synthesis and influenza virus sialidase inhibitory activity of the 5-desacetamido analogue of 2,3-didehydro-2,4-dideoxy-4-guanidinyl-N-acetylneuraminic acid (GG167)

Paul W Smith, I. D. Starkey, D. Noble, 1995 .

Pyridyl-2,5-diketopiperazines as potent, selective, and orally bioavailable oxytocin antagonists: synthesis, pharmacokinetics, and in vivo potency.

I. E. Smith, P. Woollard, J. Liddle, 2006, Journal of medicinal chemistry.

Synthesis and structure-activity relationships of indazole arylsulfonamides as allosteric CC-chemokine receptor 4 (CCR4) antagonists.

A. Hill, D. Clapham, S. Hodgson, 2013, Journal of medicinal chemistry.

Synthesis and pharmacological investigation of azaphthalazinone human histamine H(1) receptor antagonists.

C. Browning, S. Lynn, P. Procopiou, 2012, Bioorganic & medicinal chemistry.

Low molecular weight MPEG-assisted organic synthesis.

R. Hartley, S. Sollis, Marek Figlus, 2010, Chemical communications.

Dihydropyrancarboxamides related to zanamivir: a new series of inhibitors of influenza virus sialidases. 1. Discovery, synthesis, biological activity, and structure-activity relationships of 4-guanidino- and 4-amino-4H-pyran-6-carboxamides.

A Merritt, I. D. Starkey, A. Beresford, 1998, Journal of medicinal chemistry.

The discovery of phthalazinone-based human H1 and H3 single-ligand antagonists suitable for intranasal administration for the treatment of allergic rhinitis.

Kenneth L. Clark, Duncan S. Holmes, Michael Kranz, 2011, Journal of medicinal chemistry.

Synthesis and determination of absolute configuration of a non-peptidic αvβ6 integrin antagonist for the treatment of idiopathic pulmonary fibrosis.

S. Lynn, S. Macdonald, J. Pritchard, 2016, Organic & biomolecular chemistry.

Sialidase inhibitors related to zanamivir: synthesis and biological evaluation of 4H-pyran 6-ether and ketone.

R. Bethell, P. Smith, S. Sollis, 1999, Bioorganic & medicinal chemistry letters.

Short and novel stereospecific synthesis of trisubstituted 2,5-diketopiperazines.

S. Sollis, 2005, The Journal of organic chemistry.

Discovery of ( S)-3-(3-(3,5-Dimethyl-1 H-pyrazol-1-yl)phenyl)-4-(( R)-3-(2-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)ethyl)pyrrolidin-1-yl)butanoic Acid, a Nonpeptidic αvβ6 Integrin Inhibitor for the Inhaled Treatment of Idiopathic Pulmonary Fibrosis.

Joelle Le, S. Macdonald, J. Pritchard, 2018, Journal of medicinal chemistry.

A Short High Yielding Synthesis of the Potent Anti-VZV Carbocyclic Nucleoside Analogue Carba-BVDU

P. Wyatt, R. Cousins, S. Sollis, 1995 .

A Short High Yielding Synthesis of the Potent anti‐VZV Carbocyclic Nucleoside Analogue Carba‐BVDU.

P. Wyatt, R. Cousins, S. Sollis, 1996 .

Synthesis of a tetrasubstituted bicyclo [2.2.2] octane as a potential inhibitor of influenza virus sialidase.

R. Bethell, S. Lynn, P. Smith, 1999, Bioorganic & medicinal chemistry letters.

Synthesis of a Tetrasubstituted Bicyclo[2.2.2]octane as a Potential Inhibitor of Influenza Virus Sialidase.

Paul W Smith, R. Bethell, S. Lynn, 1999 .

The discovery of GSK221149A: a potent and selective oxytocin antagonist.

Michael J Allen, John Liddle, Fabrizio Nerozzi, 2008, Bioorganic & medicinal chemistry letters.

Synthesis of arrays using low molecular weight MPEG-assisted Mitsunobu reaction.

R. Hartley, S. Sollis, A. Cooper, 2011, ACS combinatorial science.

Novel Inhibitors of Influenza Sialidases Related to Zanamivir. Heterocyclic Replacements of the Glycerol Side-Chain.

Philip Smith, N. Taylor, S. Sollis, 1997 .

2,5-diketopiperazines as potent, selective, and orally bioavailable oxytocin antagonists. 3. Synthesis, pharmacokinetics, and in vivo potency.

P. Woollard, F. Nerozzi, K. Valko, 2006, Journal of medicinal chemistry.