C. Bosio

发表

Ebola virus-like particles protect from lethal Ebola virus infection

M. Mohamadzadeh, M. Aman, S. Bavari, 2003, Proceedings of the National Academy of Sciences of the United States of America.

Lipid Raft Microdomains

A. B. Will, Sina Bavari, Catharine M. Bosio, 2002, The Journal of experimental medicine.

Mitophagy Antagonism by Zika Virus Reveals Ajuba as a Regulator of PINK1-Parkin Signaling, PKR-Dependent Inflammation, and Viral Invasion of Tissues

C. Schwartz, C. Martens, S. Best, 2021 .

Virulent Francisella tularensis Destabilize Host mRNA to Rapidly Suppress Inflammation

T. Wehrly, C. Bosio, Timothy J. Bauler, 2014, Journal of Innate Immunity.

NKp30‐dependent cytolysis of filovirus‐infected human dendritic cells

G. Ruthel, M. Aman, D. Swenson, 2007, Cellular microbiology.

Ebola and Marburg viruses replicate in monocyte-derived dendritic cells without inducing the production of cytokines and full maturation.

G. Ruthel, M. Mohamadzadeh, M. Aman, 2003, The Journal of infectious diseases.

Vaccine Strain Infection Resistance to Francisella tularensis Live Interleukin-6 Is Essential for Primary

O. Foreman, K. Elkins, C. Bosio, 2014 .

Interleukin-6 Is Essential for Primary Resistance to Francisella tularensis Live Vaccine Strain Infection

M. Anver, O. Foreman, K. Elkins, 2012, Infection and Immunity.

Susceptibility to Secondary Francisella tularensis Live Vaccine Strain Infection in B-Cell-Deficient Mice Is Associated with Neutrophilia but Not with Defects in Specific T-Cell-Mediated Immunity

K. Elkins, C. Bosio, 2001, Infection and Immunity.

Efficient Immunization and Cross-Priming by Vaccine Adjuvants Containing TLR3 or TLR9 Agonists Complexed to Cationic Liposomes1

S. Dow, A. Izzo, A. Guth, 2006, The Journal of Immunology.

Liposomes TLR9 Agonists Complexed to Cationic by Vaccine Adjuvants Containing TLR3 or Efficient Immunization and Cross-Priming

S. Dow, A. Izzo, A. Guth, 2006 .

GIMAP6 regulates autophagy, immune competence, and inflammation in mice and humans

J. Demeter, M. Selbach, S. Clare, 2022, The Journal of experimental medicine.

Dendritic Cells by Inhibition of IRF 1 and Lipids Inhibit IL-12 p 40 in Primary Human SchuS 4 and SchuS 4 Francisella tularensis Small and

R. Ireland, P. Small, C. Bosio, 2013 .

Dendritic Cells by Inhibition of IRF1 and Lipids Inhibit IL-12p40 in Primary Human SchuS4 and SchuS4 Francisella tularensis

C. Bosio, Joshua B. Alinger, Rong Wang, 2013 .

Francisella tularensis SchuS 4 and SchuS 4 Lipids Inhibit IL-12 p 40 in Primary Human Dendritic Cells by Inhibition of IRF 1 and IRF 8

R. Ireland, P. Small, C. Bosio, 2013 .

Francisella tularensis SchuS4 and SchuS4 Lipids Inhibit IL-12p40 in Primary Human Dendritic Cells by Inhibition of IRF1 and IRF8

R. Ireland, P. Small, C. Bosio, 2013, The Journal of Immunology.

The Presence of CD14 Overcomes Evasion of Innate Immune Responses by Virulent Francisella tularensis in Human Dendritic Cells In Vitro and Pulmonary Cells In Vivo

C. Bosio, Jennifer C. Chase, 2009, Infection and Immunity.

An Epithelial Integrin Regulates the Amplitude of Protective Lung Interferon Responses against Multiple Respiratory Pathogens

D. Sheppard, Shalini Sharma, P. Thomas, 2016, PLoS pathogens.

Impairing RAGE signaling promotes survival and limits disease pathogenesis following SARS-CoV-2 infection in mice

Lydia M. Roberts, J. Hoidal, D. Scott, 2022, JCI insight.

Infection of B Cell-Deficient Mice with CDC 1551, a Clinical Isolate of Mycobacterium tuberculosis: Delay in Dissemination and Development of Lung Pathology1

K. Elkins, C. Bosio, D. Gardner, 2000, The Journal of Immunology.

Lung environment determines unique phenotype of alveolar macrophages.

W. Janssen, P. Henson, S. Dow, 2009, American journal of physiology. Lung cellular and molecular physiology.

Lack of the immune adaptor molecule SARM1 accelerates disease in prion infected mice and is associated with increased mitochondrial respiration and decreased expression of NRF2

S. Priola, K. Peterson, C. Bosio, 2022, PloS one.

Cutting Edge: Severe SARS-CoV-2 Infection in Humans Is Defined by a Shift in the Serum Lipidome, Resulting in Dysregulation of Eicosanoid Immune Mediators

Lydia M. Roberts, S. Farhadian, C. D. Dela Cruz, 2020, The Journal of Immunology.

Pulmonary infection induces persistent, pathogen-specific lipidomic changes influencing trained immunity

Lydia M. Roberts, S. Best, Emily Speranza, 2021, iScience.

Severe SARS-CoV-2 infection in humans is defined by a shift in the serum lipidome resulting in dysregulation of eicosanoid immune mediators

Lydia M. Roberts, S. Farhadian, A. Ko, 2020, medRxiv.

Severe SARS-CoV-2 infection in humans is defined by a shift in the serum lipidome resulting in dysregulation of eicosanoid immune mediators

Lydia M. Roberts, S. Farhadian, A. Ko, 2020, Research square.

Evaluation of a Rapid Bedside Immunochromatographic Assay for Detection of Cardiac Troponin I in Whole Blood

M. Panteghini, F. Pagani, C. Cuccia, 2001, Clinical chemistry and laboratory medicine.

Immunology of Bacterial Biodefense Agents: Francisella tularensis , Burkholderia mallei , and Yersinia pestis

C. Bosio, J. G. Shannon, J. Shannon, 2016 .

Modulation of Human Dendritic Cells by Highly Virulent Pathogens

C. Bosio, 2010 .

This information is current as Activation of Pulmonary Dendritic Cells Induces Aberrant Francisella tularensis

S. Dow, C. Bosio, 2005 .

Ebola and Marburg virus-like particles activate human myeloid dendritic cells.

G. Ruthel, M. Mohamadzadeh, M. Aman, 2004, Virology.

Role of Natural Killer Cells in Innate Protection against Lethal Ebola Virus Infection

H. Young, M. Aman, D. Swenson, 2004, The Journal of experimental medicine.

Subcutaneous remdesivir administration prevents interstitial pneumonia in rhesus macaques inoculated with SARS-CoV-2

R. Mackman, T. Cihlar, E. de Wit, 2022, Antiviral Research.

Rapid GPR183-mediated recruitment of eosinophils to the lung after Mycobacterium tuberculosis infection

A. Sher, P. Khatri, D. Barber, 2022, bioRxiv.

Enhanced detection of Rift Valley fever virus using molecular assays on whole blood samples.

H. Feldmann, R. Lindsay, A. Dusé, 2012, Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology.

T-bet Regulates Immunity to Francisella tularensis Live Vaccine Strain Infection, Particularly in Lungs

O. Foreman, K. Elkins, C. Bosio, 2014, Infection and Immunity.

Protection against pneumonic plague following oral immunization with a non-replicating vaccine.

S. Dow, M. Schriefer, C. Bosio, 2010, Vaccine.

Interferon Gamma Reprograms Host Mitochondrial Metabolism through Inhibition of Complex II To Control Intracellular Bacterial Replication

D. Scott, T. Wehrly, C. Bosio, 2019, Infection and Immunity.

Mastomys natalensis Has a Cellular Immune Response Profile Distinct from Laboratory Mice

H. Feldmann, K. Rosenke, M. Jarvis, 2021, Viruses.

Importance of B cells, but Not Specific Antibodies, in Primary and Secondary Protective Immunity to the Intracellular BacteriumFrancisella tularensis Live Vaccine Strain

K. Elkins, T. Rhinehart-Jones, C. Bosio, 1999, Infection and Immunity.

Contribution of Lipid Mediators in Divergent Outcomes following Acute Bacterial and Viral Lung Infections in the Obese Host

Lydia M. Roberts, C. Shaia, T. Wehrly, 2022, The Journal of Immunology.

Combined Molnupiravir and Nirmatrelvir Treatment Improves the Inhibitory Effect on SARS-CoV-2 in Rhesus Macaques

K. Rosenke, M. Jarvis, A. Okumura, 2022, bioRxiv.

Metabolic Reprogramming of Host Cells by Virulent Francisella tularensis for Optimal Replication and Modulation of Inflammation

D. Crane, A. Griffin, B. Jones, 2016, The Journal of Immunology.

Effective, Broad Spectrum Control of Virulent Bacterial Infections Using Cationic DNA Liposome Complexes Combined with Bacterial Antigens

B. J. Hinnebusch, J. Belisle, R. Ireland, 2010, PLoS pathogens.

Contents Vol. 6, 2014

V. Nizet, Erliang Zeng, K. Ley, 2014, Journal of Innate Immunity.

GM-CSF has disparate roles during intranasal and intradermal Francisella tularensis infection.

K. Elkins, C. Bosio, S. Kurtz, 2016, Microbes and infection.

Riboflavin salvage by Borrelia burgdorferi supports carbon metabolism and is essential for survival in the tick vector

Mollie W. Jewett, F. Gherardini, Crystal L. Richards, 2022, Molecular microbiology.

Alternative Activation of Macrophages and Induction of Arginase Are Not Components of Pathogenesis Mediated by Francisella Species

D. Crane, A. Griffin, D. Scott, 2013, PloS one.

Development of Functional and Molecular Correlates of Vaccine-Induced Protection for a Model Intracellular Pathogen, F. tularensis LVS

D. Follmann, K. Elkins, Chiung-yu Huang, 2012, PLoS pathogens.

Temporal Manipulation of Mitochondrial Function by Virulent Francisella tularensis To Limit Inflammation and Control Cell Death

T. Wehrly, C. Bosio, Forrest Jessop, 2018, Infection and Immunity.

Itaconate indirectly influences expansion of effector T cells following vaccination with Francisella tularensis live vaccine strain.

Lydia M. Roberts, T. Wehrly, C. Bosio, 2022, Cellular immunology.

A Nasal Interleukin-12 DNA Vaccine Coexpressing Yersinia pestis F1-V Fusion Protein Confers Protection against Pneumonic Plague

M. Maddaloni, Hitoki Yamanaka, Xinghong Yang, 2008, Infection and Immunity.

Mitochondrial ROS potentiates indirect activation of the AIM2 inflammasome

D. Crane, T. Wehrly, C. Bosio, 2014, Front. Microbiol..

Inclusion of Epitopes That Expand High-Avidity CD4+ T Cells Transforms Subprotective Vaccines to Efficacious Immunogens against Virulent Francisella tularensis

Lydia M. Roberts, D. Crane, T. Wehrly, 2016, The Journal of Immunology.

T Cell Metabolism Is Dependent on Anatomical Location within the Lung

Lydia M. Roberts, C. Bosio, T. J. Evans, 2019, ImmunoHorizons.

Modulation of NK/NKT Cell Responses via Francisella tularensis with Virulent B1a Cells Enhance Susceptibility to Infection

D. Crane, A. Griffin, T. Wehrly, 2013 .

Early Interaction of Yersinia pestis with APCs in the Lung1

S. Dow, C. Bosio, A. Goodyear, 2005, The Journal of Immunology.

Oral Vaccination with Salmonella Simultaneously Expressing Yersinia pestis F1 and V Antigens Protects against Bubonic and Pneumonic Plague1

B. J. Hinnebusch, Michael Tighe, R. Avci, 2007, The Journal of Immunology.

Innate and adaptive immune responses to an intracellular bacterium, Francisella tularensis live vaccine strain.

K. Elkins, C. Bosio, S. Cowley, 2003, Microbes and infection.

Virulence variation among isolates of western equine encephalitis virus in an outbred mouse model.

A. Brault, A. Powers, K. Olson, 2009, The Journal of general virology.

A Tn7-based broad-range bacterial cloning and expression system

H. Schweizer, R. Karkhoff-Schweizer, Kyoung-Hee Choi, 2005, Nature Methods.

Hydroxychloroquine prophylaxis and treatment is ineffective in macaque and hamster SARS-CoV-2 disease models

H. Feldmann, K. Rosenke, M. Jarvis, 2020, JCI insight.

Hydroxychloroquine Proves Ineffective in Hamsters and Macaques Infected with SARS-CoV-2

H. Feldmann, K. Rosenke, M. Jarvis, 2020, bioRxiv.

Clinical benefit of remdesivir in rhesus macaques infected with SARS-CoV-2

S. Anzick, C. Martens, V. Munster, 2020, Nature.

Clinical benefit of remdesivir in rhesus macaques infected with SARS-CoV-2

S. Anzick, C. Martens, V. Munster, 2020, Nature.

Innate and Adaptive Immunity to Francisella

K. Elkins, C. Bosio, S. Cowley, 2007, Annals of the New York Academy of Sciences.

Mucus sialylation determines intestinal host-commensal homeostasis

A. Griffiths, N. Warner, C. Bertozzi, 2022, Cell.

Lipids Derived from Virulent Francisella tularensis Broadly Inhibit Pulmonary Inflammation via Toll-Like Receptor 2 and Peroxisome Proliferator-Activated Receptor α

D. Crane, R. Ireland, P. Small, 2013, Clinical and Vaccine Immunology.

The Subversion of the Immune System by Francisella Tularensis

C. Bosio, 2011, Front. Microbio..

IFN-β Mediates Suppression of IL-12p40 in Human Dendritic Cells following Infection with Virulent Francisella tularensis

C. Bosio, Timothy J. Bauler, Jennifer C. Chase, 2011, The Journal of Immunology.

Human body temperature and new approaches to constructing temperature-sensitive bacterial vaccines

Francis E. Nano, Matthew D. White, Catharine M. Bosio, 2011, Cellular and Molecular Life Sciences.

Direct and Indirect Impairment of Human Dendritic Cell Function by Virulent Francisella tularensis Schu S4

J. Celli, C. Bosio, Jennifer C. Chase, 2008, Infection and Immunity.

Lydia M. Roberts, R. Germain, V. Munster, 2021, Life Science Alliance.

The Ability to Acquire Iron Is Inversely Related to Virulence and the Protective Efficacy of Francisella tularensis Live Vaccine Strain

D. Crane, C. Martens, T. Wehrly, 2018, Front. Microbiol..

Utility of mouse models in vaccine design and development

P. Marrack, M. Macleod, R. Kedl, 2012 .

Lipid Raft Microdomains: A Gateway for Compartmentalized Trafficking of Ebola and

A. B. Will, G. Ruthel, M. Aman, 2002 .

Microbiota triggers STING-type I IFN-dependent monocyte reprogramming of the tumor microenvironment

R. Rodrigues, J. Wargo, R. Goldszmid, 2021, Cell.

TRIM5α Restricts Flavivirus Replication by Targeting the Viral Protease for Proteasomal Degradation

J. Luban, S. Sawyer, Kyusik Q Kim, 2019, bioRxiv.

2019-0611 TRIM 5 alpha Restricts Flavivirus Replication by Targeting the Viral Protease for Proteasomal Degradation

Fadila, J. Luban, S. Sawyer, 2019 .

Generation of a Convalescent Model of Virulent Francisella tularensis Infection for Assessment of Host Requirements for Survival of Tularemia

D. Crane, D. Scott, C. Bosio, 2012, PloS one.

Molecular mechanisms of filovirus cellular trafficking.

M. Aman, S. Bavari, R. Panchal, 2003, Microbes and infection.

Ebola virus: the search for vaccines and treatments

J. Wilson, M. K. Hart, C. Bosio, 2001, Cellular and Molecular Life Sciences CMLS.

Orally delivered MK-4482 inhibits SARS-CoV-2 replication in the Syrian hamster model

H. Feldmann, K. Rosenke, C. Martens, 2021, Nature Communications.

Orally delivered MK-4482 inhibits SARS-CoV-2 replication in the Syrian hamster model

H. Feldmann, K. Rosenke, M. Jarvis, 2020, Research square.

Francisella tularensis Induces Aberrant Activation of Pulmonary Dendritic Cells1

S. Dow, C. Bosio, 2005, The Journal of Immunology.

Active Suppression of the Pulmonary Immune Response by Francisella tularensis Schu41

J. Belisle, H. Bielefeldt-Ohmann, C. Bosio, 2007, The Journal of Immunology.

Low Dose Vaccination with Attenuated Francisella tularensis Strain SchuS4 Mutants Protects against Tularemia Independent of the Route of Vaccination

D. Crane, J. Celli, T. Wehrly, 2012, PloS one.

Effective, Nonsensitizing Vaccination with Culture Filtrate Proteins against Virulent Mycobacterium bovis Infections in Mice

I. Orme, C. Bosio, 1998, Infection and Immunity.

A genome-wide screen uncovers multiple roles for mitochondrial nucleoside diphosphate kinase D in inflammasome activation

Eugen C. Buehler, I. Fraser, Sharat J. Vayttaden, 2021, Science Signaling.

Western diet increases COVID-19 disease severity in the Syrian hamster

D. Sturdevant, V. Munster, M. Holbrook, 2021, bioRxiv.

Neuronal excitatory-to-inhibitory balance is altered in cerebral organoid models of genetic neurological diseases

J. A. Carroll, C. Haigh, B. Groveman, 2021, Molecular brain.

Altered energy metabolism in Fatal Familial Insomnia cerebral organoids is associated with astrogliosis and neuronal dysfunction

C. Haigh, B. Groveman, S. Foliaki, 2023, PLoS genetics.

Expansion and retention of pulmonary CD4+ T cells after prime boost vaccination correlates with improved longevity and strength of immunity against tularemia.

Lydia M. Roberts, D. Crane, T. Wehrly, 2017, Vaccine.

Long lived protection against pneumonic tularemia is correlated with cellular immunity in peripheral, not pulmonary, organs.

D. Crane, C. Bosio, Rebecca V. Anderson, 2010, Vaccine.

Virulent and avirulent strains of equine arteritis virus induce different quantities of TNF-alpha and other proinflammatory cytokines in alveolar and blood-derived equine macrophages.

R. MacKay, U. Balasuriya, B. D. Moore, 2003, Virology.

Essential genes from Arctic bacteria used to construct stable, temperature-sensitive bacterial vaccines

C. Schmerk, Barry N. Duplantis, C. Bosio, 2010, Proceedings of the National Academy of Sciences.

Intracellular biology and virulence determinants of Francisella tularensis revealed by transcriptional profiling inside macrophages

D. Crane, E. Fischer, D. Sturdevant, 2009, Cellular microbiology.

B1a Cells Enhance Susceptibility to Infection with Virulent Francisella tularensis via Modulation of NK/NKT Cell Responses

D. Crane, A. Griffin, T. Wehrly, 2013, The Journal of Immunology.

Specific T-Cell-Mediated Immunity Neutrophilia but Not with Defects in B-Cell-Deficient Mice Is Associated with Live Vaccine Strain Infection in tularensis Francisella Susceptibility to Secondary

K. Elkins, C. Bosio, 2000 .

Unique Francisella Phosphatidylethanolamine Acts as a Potent Anti-Inflammatory Lipid

C. Broeckling, R. Ireland, S. Best, 2018, Journal of Innate Immunity.

A Novel Role for Plasmin-Mediated Degradation of Opsonizing Antibody in the Evasion of Host Immunity by Virulent, but Not Attenuated, Francisella tularensis1

D. Crane, C. Bosio, Shayna L. Warner, 2009, The Journal of Immunology.

Combined molnupiravir-nirmatrelvir treatment improves the inhibitory effect on SARS-CoV-2 in macaques

K. Rosenke, M. Jarvis, A. Okumura, 2022, JCI insight.

Infection of mice with Francisella as an immunological model.

Wangxue Chen, J. W. Conlan, K. Elkins, 2011, Current protocols in immunology.

Successful Protection against Tularemia in C57BL/6 Mice Is Correlated with Expansion of Francisella tularensis-Specific Effector T Cells

D. Crane, A. Griffin, T. Wehrly, 2014, Clinical and Vaccine Immunology.

Targeting 2-Oxoglutarate-Dependent Dioxygenases Promotes Metabolic Reprogramming That Protects against Lethal SARS-CoV-2 Infection in the K18-hACE2 Transgenic Mouse Model.

C. Shaia, C. Bosio, Forrest Jessop, 2023, ImmunoHorizons.

Development of Lung Pathology : Delay in Dissemination and tuberculosis Mycobacterium 1551 , a Clinical Isolate of Infection of B Cell-Deficient Mice with CDC

K. Elkins, C. Bosio, D. Gardner, 2000 .

High-Fat High-Sugar Diet-Induced Changes in the Lipid Metabolism Are Associated with Mildly Increased COVID-19 Severity and Delayed Recovery in the Syrian Hamster

D. Sturdevant, V. Munster, M. Holbrook, 2021, Viruses.

Effective inhibition of HCoV-OC43 and SARS-CoV-2 by phytochemicals in vitro and in vivo.

K. Peterson, C. Bosio, Forrest Jessop, 2023, International Journal of Antimicrobial Agents.

Francisella tularensis LVS Surface and Membrane Proteins as Targets of Effective Post-Exposure Immunization for Tularemia

J. Belisle, C. Bosio, Claudia R. Molins, 2014, Journal of proteome research.

The glycerol-3-phosphate dehydrogenases GpsA and GlpD constitute the oxidoreductive metabolic linchpin for Lyme disease spirochete host infectivity and persistence in the tick

D. Drecktrah, D. Samuels, F. Gherardini, 2022, PLoS pathogens.

Cutting Edge: Lung-Resident T Cells Elicited by SARS-CoV-2 Do Not Mediate Protection against Secondary Infection

Lydia M. Roberts, T. Wehrly, C. Bosio, 2021, The Journal of Immunology.

Route of Francisella tularensis infection informs spatiotemporal metabolic reprogramming and inflammation in mice

C. Bosio, Forrest Jessop, Benjamin Schwarz, 2023, PloS one.

A PrP EGFR signaling axis controls neural stem cell senescence through modulating cellular energy pathways

C. Haigh, B. Groveman, S. Foliaki, 2023, The Journal of biological chemistry.

Human body temperature and new approaches to constructing temperature-sensitive bacterial vaccines

Barry N. Duplantis, C. Bosio, M. White, 2011, Cellular and Molecular Life Sciences.

This information is current as Development of Lung Pathology tuberculosis: Delay in Dissemination and 1551, a Clinical Isolate of Mycobacterium Infection of B Cell-Deficient Mice with CDC

K. Elkins, C. Bosio, Donald J. Gardner, 2013 .

Intracellular biology and virulence determinants of Francisella tularensis revealed by transcriptional profiling inside macrophages

D. Crane, E. Fischer, D. Sturdevant, 2009, Cellular microbiology.

Reversible histone deacetylase activity catalyzes lysine acylation

J. Oses-Prieto, George M. Burslem, C. Bosio, 2023, bioRxiv.

Effects of sEH inhibition on the eicosanoid and cytokine storms in SARS‐CoV‐2‐infected mice

D. Zeldin, M. Edin, F. Lih, 2024, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Review Ebola virus: the search for vaccines and treatments

C. Bosio, J. A. Wilson, M. K. Hart, 2001 .

The intracellular growth of the vacuolar pathogen Legionella pneumophila is dependent on the acyl chain composition of host membranes

C. Bosio, Stanimir S. Ivanov, A. Dragoi, 2023, bioRxiv.

The PINK1/Parkin pathway of mitophagy exerts a protective effect during prion disease

S. Priola, C. Bosio, Forrest Jessop, 2024, PloS one.

Temporal Requirement for Pulmonary Resident and Circulating T Cells during Virulent Francisella tularensis Infection

Lydia M. Roberts, D. Crane, R. Ireland, 2018, The Journal of Immunology.

Mitochondrial Hyperactivity and Reactive Oxygen Species Drive Innate Immunity to the Yellow Fever Virus-17D Live-Attenuated Vaccine

Alison W. Ashbrook, M. MacDonald, C. Bosio, 2024, bioRxiv.