Cheng Huang

发表

Crabapple fruit extracts lower hypercholesterolaemia in high-fat diet-induced obese mice

Siong H. Tan, Zhiqin Zhou, Yun-cong Yao, 2016 .

2-Hydroxyeupatolide attenuates inflammatory responses via the inhibiting of NF-κB signaling pathways

Siong H. Tan, Zhiqin Zhou, Mingxia Li, 2017 .

Coptisine protects cardiomyocyte against hypoxia/reoxygenation-induced damage via inhibition of autophagy.

Ming Gu, Dongshan Wang, Shengjie Fan, 2017, Biochemical and biophysical research communications.

Ophiopogonin D inhibits cell proliferation, causes cell cycle arrest at G2/M, and induces apoptosis in human breast carcinoma MCF-7 cells.

Cheng Huang, Lu Zhang, Qing-qing Zang, 2016, Journal of integrative medicine.

Berbamine reduces body weight via suppression of small GTPase Rab8a activity and activation of paraventricular hypothalamic neurons in obese mice.

Yongli Han, Shengjie Fan, Cheng Huang, 2022, European journal of pharmacology.

Effects of Fortunella margarita Fruit Extract on Metabolic Disorders in High-Fat Diet-Induced Obese C57BL/6 Mice

Siong H. Tan, Yiming Li, Wanpeng Xi, 2014, PloS one.

Sophoricoside is a selective LXRβ antagonist with potent therapeutic effects on hepatic steatosis of mice

G. Ji, Fei Li, Yu Zhang, 2020, Phytotherapy research : PTR.

Morin, a novel liver X receptor α/β dual antagonist, has potent therapeutic efficacy for nonalcoholic fatty liver diseases

G. Ji, Q. Tong, Ming Gu, 2017, British journal of pharmacology.

Identification of isotschimgine as a novel farnesoid X receptor agonist with potency for the treatment of obesity in mice.

Shengjie Fan, Cheng Huang, Zunli Ke, 2020, Biochemical and biophysical research communications.

Extract of Kuding Tea Prevents High-Fat Diet-Induced Metabolic Disorders in C57BL/6 Mice via Liver X Receptor (LXR) β Antagonism

Zhiqin Zhou, G. Ji, Ming Gu, 2012, PloS one.

Plantago asiatica L. Seed Extract Improves Lipid Accumulation and Hyperglycemia in High-Fat Diet-Induced Obese Mice

Li Yang, Zhengtao Wang, Zeyun Li, 2017, International journal of molecular sciences.

Polydatin protects against acute cholestatic liver injury in mice via the inhibition of oxidative stress and endoplasmic reticulum stress

Q. Feng, Peiyong Zheng, Shengjie Fan, 2019, Journal of Functional Foods.

Bitter substances from plants used in traditional Chinese medicine exert biased activation of human bitter taste receptors

M. Behrens, W. Meyerhof, Ming Gu, 2018, Chemical biology & drug design.

Therapeutic effects of herbal formula Huangqisan on metabolic disorders via SREBF1, SCD1 and AMPK signaling pathway.

G. Ji, M. Gao, Shengjie Fan, 2020, Journal of integrative medicine.

Screening of anti-cancer agent using zebrafish: comparison with the MTT assay.

Yigen Li, Jiulin Du, Cheng Huang, 2012, Biochemical and biophysical research communications.

Radix Stellariae extract prevents high-fat-diet-induced obesity in C57BL/6 mice by accelerating energy metabolism

Cheng Huang, Xin Liu, Baican Yang, 2017, PeerJ.

Extract of Wax Gourd Peel Prevents High-Fat Diet-Induced Hyperlipidemia in C57BL/6 Mice via the Inhibition of the PPARγ Pathway

G. Ji, Ming Gu, Yu Zhang, 2013, Evidence-based complementary and alternative medicine : eCAM.

Separation and peroxisome proliferator-activated receptor-γ agonist activity evaluation of synthetic racemic bavachinin enantiomers.

Weiliang Zhu, Jiye Shi, Yiming Li, 2015, Bioorganic & medicinal chemistry letters.

Extract of okra lowers blood glucose and serum lipids in high-fat diet-induced obese C57BL/6 mice.

Yiming Li, Mingxia Li, Yu Zhang, 2014, The Journal of nutritional biochemistry.

Microbial transformation of prenylflavonoids from Psoralea corylifolia by using Cunninghamella blakesleeana and C. elegans

Cheng Huang, Li Feng, Fujiang Guo, 2015 .

Extracts of Rhizoma Polygonati Odorati Prevent High-Fat Diet-Induced Metabolic Disorders in C57BL/6 Mice

G. Ji, Ming Gu, Yu Zhang, 2013, PloS one.

Polyphyllin I induces mitophagic and apoptotic cell death in human breast cancer cells by increasing mitochondrial PINK1 levels

Han-Ming Shen, Cheng Huang, Jing Zhou, 2017, Oncotarget.

Silymarin Ameliorates Metabolic Dysfunction Associated with Diet-Induced Obesity via Activation of Farnesyl X Receptor

G. Ji, Q. Tong, Ming Gu, 2016, Front. Pharmacol..

Dietary component isorhamnetin is a PPARγ antagonist and ameliorates metabolic disorders induced by diet or leptin deficiency

G. Ji, Q. Tong, Ming Gu, 2016, Scientific Reports.

Luteolin alleviates alcoholic liver disease induced by chronic and binge ethanol feeding in mice.

Yuan Cheng, Yi Pan, Rui Zhang, 2014, The Journal of nutrition.

PPARγ phase separates with RXRα at PPREs to regulate target gene expression

Hanhui Ma, Xingxu Huang, A. Liang, 2022, Cell discovery.

Isotschimgine alleviates nonalcoholic steatohepatitis and fibrosis via FXR agonism in mice

Peiyong Zheng, Shengjie Fan, Cheng Huang, 2021, Phytotherapy research : PTR.

Citrus reticulata Blanco peel extract ameliorates hepatic steatosis, oxidative stress and inflammation in HF and MCD diet-induced NASH C57BL/6 J mice.

Siong H. Tan, Zhiqin Zhou, Cheng Huang, 2020, The Journal of nutritional biochemistry.

Chicken bile powder protects against α-naphthylisothiocyanate-induced cholestatic liver injury in mice

Zheng-Tao Wang, Ming Gu, Cheng Huang, 2017, Oncotarget.

Preventive and ameliorating effects of citrus D-limonene on dyslipidemia and hyperglycemia in mice with high-fat diet-induced obesity.

Zhiqin Zhou, Ming Gu, Yu Zhang, 2013, European journal of pharmacology.

Palladium complexes affect the aggregation of human prion protein PrP106-126.

Yiming Li, Cheng Huang, Xuesong Wang, 2011, Inorganic chemistry.

Targeting SMARCAL1 as a novel strategy for cancer therapy.

Shengjie Fan, Cheng Huang, Lu Zhang, 2012, Biochemical and biophysical research communications.

Scrodentoids F–I, four C 19 -norditerpenoids from Scrophularia dentata

Kaixian Chen, Cheng Huang, Yuanyuan Zhao, 2016 .

Okra polysaccharide improves metabolic disorders in high-fat diet-induced obese C57BL/6 mice.

Yu Zhang, Lu Guo, Shengjie Fan, 2013, Molecular nutrition & food research.

A novel autophagy/mitophagy inhibitor liensinine sensitizes breast cancer cells to chemotherapy through DNM1L-mediated mitochondrial fission

P. Li, Han-Ming Shen, Cheng Huang, 2015, Autophagy.

PMFs-rich Citrus extract prevents the development of non-alcoholic fatty liver disease in C57BL/6J mice induced by a high-fat diet

Siong H. Tan, Zhiqin Zhou, Ziyan Zhao, 2018, Journal of Functional Foods.

Ethyl acetate extract of crabapple fruit is the cholesterol-lowering fraction

Dongshan Wang, Shengjie Fan, Cheng Huang, 2017 .

Prenylflavone derivatives from the seeds of Psoralea corylifolia exhibited PPAR-γ agonist activity

Yiming Li, Cheng Huang, Yuanyuan Zhao, 2016 .

Targeting 17q23 amplicon to overcome the resistance to anti-HER2 therapy in HER2+ breast cancer

Yifan Sun, Yujing Li, Cecil Han, 2018, Nature Communications.

Targeting adipocyte apoptosis: a novel strategy for obesity therapy.

Yu Zhang, Cheng Huang, Yu Zhang, 2012, Biochemical and biophysical research communications.

Somatic mutation of the cohesin complex subunit confers therapeutic vulnerabilities in cancer

Yujing Li, Xinna Zhang, Xiongbin Lu, 2018, The Journal of clinical investigation.

Five new cyotoxic steroidal glycosides from the fruits of Solanum torvum.

Yiming Li, Cheng Huang, Lu Zhang, 2014, Fitoterapia.

Citrus ichangensis Peel Extract Exhibits Anti-Metabolic Disorder Effects by the Inhibition of PPARγ and LXR Signaling in High-Fat Diet-Induced C57BL/6 Mouse

Yiming Li, Zhiqin Zhou, Ming Gu, 2012, Evidence-based complementary and alternative medicine : eCAM.

Mangiferin and organ fibrosis: A mini review

Shengjie Fan, Cheng Huang, Li-jun Zhang, 2020, BioFactors.

Extracts of Pomelo Peels Prevent High-Fat Diet-Induced Metabolic Disorders in C57BL/6 Mice through Activating the PPARα and GLUT4 Pathway

Yiming Li, Zhiqin Zhou, Ming Gu, 2013, PloS one.

Prenylated flavonoid‐standardized extract from seeds of Psoralea corylifolia L. activated fat browning in high‐fat diet–induced obese mice

Cheng Huang, Yuanyuan Zhao, Fujiang Guo, 2019, Phytotherapy research : PTR.

Citrange Fruit Extracts Alleviate Obesity-Associated Metabolic Disorder in High-Fat Diet-Induced Obese C57BL/6 Mouse

Yiming Li, Wanpeng Xi, Zhiqin Zhou, 2013, International journal of molecular sciences.

Bavachinin analogues as agonists of pan-peroxisome proliferator-activated receptors

Weiliang Zhu, Yiming Li, Cheng Huang, 2018, Medicinal Chemistry Research.

Bavachinin analogues as agonists of pan-peroxisome proliferator-activated receptors

Weiliang Zhu, Yiming Li, Cheng Huang, 2018, Medicinal Chemistry Research.

Harmine is an inflammatory inhibitor through the suppression of NF-κB signaling.

Siong H. Tan, Changhong Wang, Mingxia Li, 2017, Biochemical and biophysical research communications.

Targeting stress granules: A novel therapeutic strategy for human diseases

Zhigang Jin, Shengjie Fan, Cheng Huang, 2020, Pharmacological Research.

MicroRNAs in DNA Damage Response, Carcinogenesis, and Chemoresistance.

Yujing Li, Xiongbin Lu, Cheng Huang, 2017, International review of cell and molecular biology.

Atractylenolide I enhances responsiveness to immune checkpoint blockade therapy by activating tumor antigen presentation.

Tao Yu, Yunlong Liu, A. Mosley, 2021, The Journal of clinical investigation.

Rhein Reduces Fat Weight in db/db Mouse and Prevents Diet-Induced Obesity in C57Bl/6 Mouse through the Inhibition of PPARγ Signaling

Yiming Li, Ming Gu, Yu Zhang, 2012, PPAR research.

Notoginsenoside Fe suppresses diet induced obesity and activates paraventricular hypothalamic neurons

Shengjie Fan, Cheng Huang, Liufang Yin, 2019, RSC advances.

Phase III study of dulanermin (recombinant human tumor necrosis factor-related apoptosis-inducing ligand/Apo2 ligand) combined with vinorelbine and cisplatin in patients with advanced non-small-cell lung cancer

C. Bai, B. Han, Qiang Li, 2018, Investigational New Drugs.

Pepper component 7-ethoxy-4-methylcoumarin, a novel dopamine D2 receptor agonist, ameliorates experimental Parkinson's disease in mice and Caenorhabditis elegans.

Xiaojun Wu, Xingxu Huang, Yu Zhang, 2020, Pharmacological research.

Natural modulators of liver X receptors.

Cheng Huang, 2014, Journal of integrative medicine.

Design, Synthesis, and Structure–Activity Relationships of Bavachinin Analogues as Peroxisome Proliferator‐Activated Receptor γ Agonists

Weiliang Zhu, Jiye Shi, Zhuo Yang, 2017, ChemMedChem.

Inhibition of Human Neutrophil Elastase by Pentacyclic Triterpenes

Weiliang Zhu, Kaixian Chen, Cheng Huang, 2013, PloS one.

Direct interaction of ONO-5046 with human neutrophil elastase through ¹H NMR and molecular docking.

Weiliang Zhu, Yiming Li, Cheng Huang, 2012, International journal of biological macromolecules.

Amplification of USP13 drives ovarian cancer metabolism

Yujing Li, Cecil Han, Guohui Wan, 2016, Nature Communications.

Targeted isolation and identification of bioactive compounds lowering cholesterol in the crude extracts of crabapples using UPLC-DAD-MS-SPE/NMR based on pharmacology-guided PLS-DA.

Dongshan Wang, Cheng Huang, K. Hu, 2018, Journal of pharmaceutical and biomedical analysis.

SARS-CoV-2 nucleocapsid protein phase separates with G3BPs to disassemble stress granules and facilitate viral production

Q. Ding, Zhigang Jin, Peixiang Ma, 2021, Science Bulletin.

Buyang Huanwu Decoction Attenuates Infiltration of Natural Killer Cells and Protects Against Ischemic Brain Injury

Zhifei Wang, Changhong Wang, Z. Ke, 2018, Cellular Physiology and Biochemistry.

Berberine inhibits PTP1B activity and mimics insulin action.

Yuebo Zhang, Yuebo Zhang, Cheng Huang, 2010, Biochemical and biophysical research communications.

Deoxyschizandrin ameliorates obesity and non‐alcoholic fatty liver disease: Involvement of dual Farnesyl X receptor/G protein‐coupled bile acid receptor 1 activation and leptin sensitization

Ming Gu, Shengjie Fan, Cheng Huang, 2023, Phytotherapy research : PTR.

Extract of Schisandra chinensis fruit protects against metabolic dysfunction in high‐fat diet induced obese mice via FXR activation

Yuwei Jiang, Haiyan Song, G. Ji, 2020, Phytotherapy research : PTR.

Betulinic acid alleviates endoplasmic reticulum stress‐mediated nonalcoholic fatty liver disease through activation of farnesoid X receptors in mice

G. Ji, Ming Gu, Shengjie Fan, 2019, British journal of pharmacology.

Cycloastragenol improves hepatic steatosis by activating farnesoid X receptor signalling

G. Ji, Ming Gu, Shengjie Fan, 2017, Pharmacological research.

Identification of an allosteric hotspot for additive activation of PPARγ in antidiabetic effects.

Shaoyong Lu, Yiming Li, K. Song, 2021, Science bulletin.

Ginkgolide B lowers body weight and ameliorates hepatic steatosis in high-fat diet-induced obese mice correlated with pregnane X receptor activation

Dongshan Wang, Shengjie Fan, Cheng Huang, 2017 .

Red bayberry extract prevents high-fat diet-induced metabolic disorders in C57BL/6 mice

Yu Zhang, Cheng Huang, Li Feng, 2015 .

Prim-O-glucosylcimifugin induces cell cycle arrest and apoptosis in acute lymphoblastic leukemia cells

Xiongbin Lu, Cheng Huang, Lu Zhang, 2017, Anti-cancer drugs.

A neural basis for brain leptin action on reducing type 1 diabetic hyperglycemia

B. Arenkiel, Yungang Lu, Mingshan Xue, 2021, Nature Communications.

The melanocortin action is biased toward protection from weight loss in mice

B. Arenkiel, Cheng Huang, Zhiying Jiang, 2023, Nature communications.

Hordenine improves Parkinsonian‐like motor deficits in mice and nematodes by activating dopamine D2 receptor‐mediated signaling

Xiaojun Wu, Xingxu Huang, Yu Zhang, 2023, Phytotherapy research : PTR.

Bavachinin, as a novel natural pan-PPAR agonist, exhibits unique synergistic effects with synthetic PPAR-γ and PPAR-α agonists on carbohydrate and lipid metabolism in db/db and diet-induced obese mice

Weiliang Zhu, Kaixian Chen, Yiming Li, 2016, Diabetologia.

Tangeretin promotes lifespan associated with insulin/insulin‐like growth factor‐1 signaling pathway and heat resistance in Caenorhabditis elegans

Zhiqin Zhou, Shengjie Fan, Cheng Huang, 2021, BioFactors.

Extracts of Coreopsis tinctoria Nutt. Flower Exhibit Antidiabetic Effects via the Inhibition of α-Glucosidase Activity

Yu Zhang, Cheng Huang, H. Tan, 2016, Journal of diabetes research.

Protopanaxatriol, a novel PPARγ antagonist from Panax ginseng, alleviates steatosis in mice

Yu Zhang, Li Feng, Guang Ji, 2014, Scientific Reports.

Timosaponin derivative YY-23 acts as a non-competitive NMDA receptor antagonist and exerts a rapid antidepressant-like effect in mice

Bing Zhang, Cheng Huang, Zhiwen Fu, 2015, Acta Pharmacologica Sinica.

Qushi Huayu Decoction Inhibits Hepatic Lipid Accumulation by Activating AMP-Activated Protein Kinase In Vivo and In Vitro

Xiao-Jun Gou, Q. Feng, Yi-Yang Hu, 2013, Evidence-based complementary and alternative medicine : eCAM.

Targeting 17q23 amplicon to overcome the resistance to anti-HER2 therapy in HER2+ breast cancer

Yujing Li, Cecil Han, Xinna Zhang, 2018, Nature Communications.

Saponin-enriched sea cucumber extracts exhibit an antiobesity effect through inhibition of pancreatic lipase activity and upregulation of LXR-β signaling

Yiming Li, Yan Chen, Lu Guo, 2016, Pharmaceutical biology.

Profound and rapid reduction in body temperature induced by the melanocortin receptor agonists.

Yan Xia, Eun Ran Kim, Shengjie Fan, 2014, Biochemical and biophysical research communications.

Pregnane X receptor agonist nomilin extends lifespan and healthspan in preclinical models through detoxification functions

Y. Liu, Changhong Wang, Yongli Han, 2023, Nature communications.

An Indirect Action Contributes to C-Fos Induction in Paraventricular Hypothalamic Nucleus by Neuropeptide Y

Eun Ran Kim, Yong Xu, Shengjie Fan, 2016, Scientific Reports.

Nomilin and its analogue obacunone alleviate NASH and hepatic fibrosis in mice via enhancing antioxidant and anti‐inflammation capacity

Y. Liu, Yongli Han, Shengjie Fan, 2023, BioFactors.

Mangiferin relieves CCl4-induced liver fibrosis in mice

Shengjie Fan, Cheng Huang, Liufang Yin, 2023, Scientific Reports.

Prenylflavone derivatives from Broussonetia papyrifera, inhibit the growth of breast cancer cells in vitro and in vivo

Xintian Zhang, Zhaoyi Wang, Cheng Huang, 2013 .

Harmine is an inflammatory inhibitor through the suppression of NF-κB signaling.

Siong H. Tan, Changhong Wang, Mingxia Li, 2017, Biochemical and Biophysical Research Communications - BBRC.

Protopanaxadiol alleviates obesity in high-fat diet-fed mice via activation of energy-sensing neuron in the paraventricular nucleus of hypothalamus.

Shengjie Fan, Cheng Huang, Hui Chen, 2019, Biochemical and biophysical research communications.

A piggyBac-based TANGO GFP assay for high throughput screening of GPCR ligands in live cells

Yueming Xu, Yu Zhang, Cheng Huang, 2019, Cell Communication and Signaling.

Targeting adipocyte apoptosis: a novel strategy for obesity therapy.

Yu Zhang, Cheng Huang, 2012, Biochemical and biophysical research communications.

Somatic mutation of the cohesin complex subunit confers therapeutic vulnerabilities in cancer

Yujing Li, Xinna Zhang, Xiongbin Lu, 2018, The Journal of clinical investigation.