S. Ono

发表

Role of Hypoxia-Inducible Factor 1&agr; in T Cells as a Negative Regulator in Development of Vascular Remodeling

M. Ueki, K. Aihara, Y. Takahama, 2010, Arteriosclerosis, thrombosis, and vascular biology.

Induction of the chemokine receptor CXCR3 on TCR‐stimulated T cells: dependence on the release from persistent TCR‐triggering and requirement for IFN‐γ stimulation

W. Park, H. Fujiwara, P. Gao, 2002, European journal of immunology.

The capacity of the natural ligands for CD28 to drive IL-4 expression in naïve and antigen-primed CD4+ and CD8+ T cells.

Y. Yashiro‐Ohtani, H. Fujiwara, J. Shimizu, 2004, International immunology.

The capacity of the natural ligands for CD28 to drive IL-4 expression in naïve and antigen-primed CD4+ and CD8+ T cells.

Y. Yashiro‐Ohtani, H. Fujiwara, J. Shimizu, 2004, International immunology.

IL-12 produced by antigen-presenting cells induces IL-2-independent proliferation of T helper cell clones.

G. Trinchieri, S. Maruo, H. Fujiwara, 1996, Journal of immunology.

Epithelial membrane protein 3 (Emp3) downregulates induction and function of cytotoxic T lymphocytes by macrophages via TNF-α production.

T. Ishii, K. Miyake, S. Saitoh, 2017, Cellular immunology.

A role for CD9 molecules in T cell activation

H. Fujiwara, R. Abe, C. Wood, 1996, The Journal of experimental medicine.

Rapid Growth and Spontaneous Metastasis of Human Germinal Tumors Ectopically Transplanted into Scid (Severe Combined Immunodeficiency) and Scid‐nudestreaker Mice

T. Hongyo, H. Inohara, Y. Takahama, 1991, Japanese journal of cancer research : Gann.

A novel function of B lymphocytes from normal mice to suppress autoimmunity in (NZB × NZW)F1 mice

S. Yamada, T. Hamaoka, S. Ono, 2000, Immunology.

Enhanced induction of antitumor T-cell responses by cytotoxic T lymphocyte-associated molecule-4 blockade: the effect is manifested only at the restricted tumor-bearing stages.

J. Bluestone, H. Fujiwara, T. Walunas, 1997, Cancer research.

Myeloid suppressor cell‐associated immune dysfunction in CSA1M fibrosarcoma tumor‐bearing mice

H. Fujiwara, Jian-Ping Zuo, S. Ono, 2007, Cancer science.

A Role of Interferon-γ (IFN-γ) in Tumor Immunity: T Cells with the Capacity to Reject Tumor Cells Are Generated But Fail to Migrate to Tumor Sitesin IFN-γ-deficient Mice

H. Fujiwara, P. Gao, T. Hamaoka, 2001 .

Regulation of T cell‐dependent and ‐independent IL‐12 production by the three Th2‐type cytokines IL‐10, IL‐6, and IL‐4

G. Trinchieri, S. Maruo, H. Fujiwara, 1997, Journal of leukocyte biology.

The chemokine receptor antagonist, TAK‐779, decreased experimental autoimmune encephalomyelitis by reducing inflammatory cell migration into the central nervous system, without affecting T cell function

Jian-Ping Zuo, Wei Tang, S. Ono, 2009, British journal of pharmacology.

Immunologic abnormality in NZB/NZW F1 mice. Thymus-independent occurrence of B cell abnormality and requirement for T cells in the development of autoimmune disease, as evidenced by an analysis of the athymic nude individuals.

K. Dobashi, F. Hirayama, Y. Ohsugi, 1988, Journal of immunology.

(5R)-5-Hydroxytriptolide Attenuated Collagen-Induced Arthritis in DBA/1 Mice via Suppressing Interferon-γ Production and Its Related Signaling

H. Fujiwara, Jian-Ping Zuo, Wei-Yu Tang, 2006, Journal of Pharmacology and Experimental Therapeutics.

Induction of Tumor Regression by Administration of B7-Ig Fusion Proteins: Mediation by Type 2 CD8+ T Cells and Dependence on IL-4 Production1

M. Kogo, H. Fujiwara, V. Ling, 2004, The Journal of Immunology.

Anti–HER-2/neu Immune Responses Are Induced before the Development of Clinical Tumors but Declined following Tumorigenesis in HER-2/neu Transgenic Mice

Y. Yura, H. Fujiwara, T. Hamaoka, 2004, Cancer Research.

IFN-α Acts on T-Cell Receptor-Triggered Human Peripheral Leukocytes to Up-Regulate CCR5 Expression on CD4+ and CD8+ T Cells

H. Fujiwara, G. Shearer, T. Hamaoka, 2001, Journal of Clinical Immunology.

Evidence for existence of two distinct TNP-Ficoll-responsive B cell subpopulations preferentially reactive either to a T cell-replacing factor (B151-TRF) or to a signal from accessory cells.

K. Takatsu, K. Miyake, T. Hamaoka, 1986, Journal of immunology.

Regulatory effects of Spirulina complex polysaccharides on growth of murine RSV‐M glioma cells through Toll‐like receptor 4

A. Tominaga, T. Taguchi, Y. Fujimoto, 2013, Microbiology and immunology.

B cell-mediated down-regulation of IFN-gamma and IL-12 production induced during anti-tumor immune responses in the tumor-bearing state.

S. Maruo, H. Fujiwara, T. Hamaoka, 1998, International immunology.

Disparate functions of I‐A and I‐E molecules on B cells as evidenced by the inhibition with anti‐I‐A and anti‐I‐E antibodies of polyclonal B cell activation

K. Ishihara, Y. Takahama, T. Hamaoka, 1989, European journal of immunology.

B7.2-Ig fusion proteins enhance IL-4-dependent differentiation of tumor-sensitized CD8+ cytotoxic T lymphocyte precursors.

M. Kogo, H. Fujiwara, K. Dunussi-Joannopoulos, 2005, International immunology.

Involvement of I-A-restricted B-B cell interaction in the polyclonal B cell differentiation induced by lipopolysaccharide.

K. Ishihara, Y. Takahama, T. Hamaoka, 1990, Advances in experimental medicine and biology.

Transforming growth factor-beta (TGF-beta)-mediated immunosuppression in the tumor-bearing state: enhanced production of TGF-beta and a progressive increase in TGF-beta susceptibility of anti-tumor CD4+ T cell function.

H. Fujiwara, T. Katagiri, T. Hamaoka, 1993, Japanese journal of cancer research : Gann.

Minireview: Divergent roles of α7 nicotinic acetylcholine receptors expressed on antigen-presenting cells and CD4+ T cells in the regulation of T cell differentiation.

K. Kawashima, S. Ono, H. Misawa, 2020, International immunopharmacology.

Distinct Roles of α7 nAChRs in Antigen-Presenting Cells and CD4+ T Cells in the Regulation of T Cell Differentiation

K. Kawashima, S. Ono, H. Misawa, 2019, Front. Immunol..

Dependence on IL-4 Production T Cells and + Mediation by Type 2 CD8 Administration of B7-Ig Fusion Proteins: Induction of Tumor Regression by

M. Kogo, H. Fujiwara, V. Ling, 2004 .

Recovery of antitumor CD4+ T cell responsiveness, suppressed in the tumor-bearing state, by release from tumor burden

H. Fujiwara, T. Hamaoka, J. Zou, 2005, Journal of Cancer Research and Clinical Oncology.

Suppression of Anti‐tumor CD4+ T Cell Responsiveness in the Tumor‐bearing State and Its Recovery in in vitro Culture Free of Tumor Burden

H. Fujiwara, T. Hamaoka, J. Zou, 1993, Japanese journal of cancer research : Gann.

Tumor-bearing mice exhibit a progressive increase in tumor antigen-presenting cell function and a reciprocal decrease in tumor antigen-responsive CD4+ T cell activity.

H. Fujiwara, J. Shimizu, T. Hamaoka, 1992, Journal of immunology.

IFN-alpha acts on T-cell receptor-triggered human peripheral leukocytes to up-regulate CCR5 expression on CD4+ and CD8+ T cells.

H. Fujiwara, G. Shearer, T. Hamaoka, 2001, Journal of clinical immunology.

Monoclonal antibodies to Pgp-1/CD44 block lympho-hemopoiesis in long- term bone marrow cultures

K. Miyake, T. Hamaoka, K. Medina, 1990, The Journal of experimental medicine.

Effects of Edible Algae Polysaccharides on Allergic, Inflammatory, and Anti-Tumor Responses Through Toll-Like Receptor 4

A. Tominaga, T. Taguchi, K. Shimizu, 2010 .

The unique target specificity of a nonpeptide chemokine receptor antagonist: selective blockade of two Th1 chemokine receptors CCR5 and CXCR3

Y. Yashiro‐Ohtani, N. Sugimoto, H. Fujiwara, 2003, Journal of leukocyte biology.

A Novel Function of Vα14+CD4+NKT Cells: Stimulation of IL-12 Production by Antigen-Presenting Cells in the Innate Immune System

H. Fujiwara, M. Taniguchi, T. Hamaoka, 1999, The Journal of Immunology.

Polyclonal B cell activation by a B cell differentiation factor, B151-TRF2. II. Evidence for interaction of B151-TRF2 with glycoprotein on B cell membrane via recognition of terminal N-acetyl-D-glucosamine residue(s).

Y. Takahama, K. Miyake, T. Hamaoka, 1986, Journal of Immunology.

Identification of two distinct factors, B151-TRF1 and B151-TRF2, inducing differentiation of activated B cells and small resting B cells into antibody-producing cells.

W. Paul, K. Dobashi, Y. Takahama, 1986, Journal of Immunology.

Expression and Function of the Cholinergic System in Immune Cells

K. Kawashima, S. Ono, H. Misawa, 2017, Front. Immunol..

Physiological functions of the cholinergic system in immune cells.

K. Kawashima, S. Ono, H. Misawa, 2017, Journal of pharmacological sciences.

A role of interferon-gamma (IFN-gamma) in tumor immunity: T cells with the capacity to reject tumor cells are generated but fail to migrate to tumor sites in IFN-gamma-deficient mice.

H. Fujiwara, P. Gao, T. Hamaoka, 2001, Cancer research.

Polyclonal B cell activation by a B cell differentiation factor, B151-TRF2. III. B151-TRF2 as a B cell differentiation factor closely associated with autoimmune disease.

K. Dobashi, Y. Takahama, T. Hamaoka, 1987, Journal of immunology.

Muscle regeneration by reconstitution with bone marrow or fetal liver cells from green fluorescent protein-gene transgenic mice.

Hiroshi Yamamoto, K. Tsujikawa, S. Takeda, 2002, Journal of cell science.

Type II collagen-induced murine arthritis: induction of arthritis depends on antigen-presenting cell function as well as susceptibility of host to an anticollagen immune response.

H. Fujiwara, T. Hamaoka, K. Orito, 1992, Journal of Immunology.

A non‐peptide CCR5 antagonist inhibits collagen‐induced arthritis by modulating T cell migration without affecting anti‐collagen T cell responses

H. Fujiwara, P. Gao, S. Obika, 2002, European journal of immunology.

Differential expression of inducible nitric oxide synthase and IL-12 between peritoneal and splenic macrophages stimulated with LPS plus IFN-gamma is associated with the activation of extracellular signal-related kinase.

Wei Tang, Jian-Ping Zuo, S. Ono, 2006, International immunology.

Regulatory mechanisms for production of IFN-gamma and TNF by antitumor T cells or macrophages in the tumor-bearing state.

N. Mukaida, K. Matsushima, N. Yamamoto, 1995, Journal of immunology.

Spirulina lipopolysaccharides inhibit tumor growth in a Toll-like receptor 4-dependent manner by altering the cytokine milieu from interleukin-17/interleukin-23 to interferon-γ

A. Tominaga, T. Taguchi, S. Ono, 2017, Oncology reports.

Localization of recombination activating gene 1/green fluorescent protein (RAG1/GFP) expression in secondary lymphoid organs after immunization with T-dependent antigens in rag1/gfp knockin mice.

S. Bauer, H. Igarashi, T. Suda, 2001, Blood.

α7 nAChRs expressed on antigen presenting cells are insensitive to the conventional antagonists α-bungarotoxin and methyllycaconitine.

K. Kawashima, S. Ono, Masato Mashimo, 2020, International Immunopharmacology.

Requirement for IFN-γ in IL-12 production induced by collaboration between Vα14+ NKT cells and antigen-presenting cells

H. Fujiwara, T. Hamaoka, M. Tomura, 2000 .

Tumor Vaccination That Enhances Antitumor T-Cell Responses Does Not Inhibit the Growth of Established Tumors Even in Combination With Interleukin-12 Treatment: The Importance of Inducing Intratumoral T-Cell Migration

M. Nakahira, H. Fujiwara, P. Gao, 2000, Journal of immunotherapy.

Induction of surface CCR4 and its functionality in mouse Th2 cells is regulated differently during Th2 development

M. Kogo, Y. Yashiro‐Ohtani, H. Fujiwara, 2005, Journal of leukocyte biology.

Regulation of B-cell differentiation: interactions of factors and corresponding receptors.

T. Hamaoka, S. Ono, 1986, Annual review of immunology.

The Origin of Antibody‐Forming Cells Detected in the Bone Marrow after Thymus‐Independent Antigen‐Stimulation and Abnormality in Migration of B Cells of X‐Linked Immunodeficient CBA/N Mice

K. Miyake, T. Hamaoka, S. Ono, 1987, Microbiology and immunology.

IL-12 as Well as IL-2 Upregulates CCR5 Expression on T Cell Receptor-Triggered Human CD4+ and CD8+ T Cells

H. Fujiwara, G. Shearer, P. Gao, 2001, Journal of Clinical Immunology.

B cells regulate CD40 ligand-induced IL-12 production in antigen-presenting cells (APC) during T cell/APC interactions.

G. Trinchieri, S. Maruo, H. Fujiwara, 1997, Journal of immunology.

Requirement for IFN-gamma in IL-12 production induced by collaboration between v(alpha)14(+) NKT cells and antigen-presenting cells.

H. Fujiwara, T. Hamaoka, M. Tomura, 2000, International immunology.

The development of peritumoral stroma required for IL-12 induced tumor regression depends on the T cell/IFN-gamma-involving host-tumor interaction.

H. Fujiwara, P. Gao, T. Hamaoka, 2000, International Journal of Oncology.

IL‐12 plays a pivotal role in LFA‐1‐mediated T cell adhesiveness by up‐regulation of CCR5 expression

M. Kogo, Y. Yashiro‐Ohtani, M. Kurimoto, 2001, Journal of leukocyte biology.

Spirulina Complex Polysaccharides Suppress the Growth of Glioma in T Lymphocyte- and Macrophage-dependent Manner

A. Tominaga, T. Taguchi, T. Yawata, 2014 .

GTS-21 Enhances Regulatory T Cell Development from T Cell Receptor-Activated Human CD4+ T Cells Exhibiting Varied Levels of CHRNA7 and CHRFAM7A Expression

K. Kawashima, T. Kasahara, S. Ono, 2023, International journal of molecular sciences.

Suppression of Anti‐tumor CD4+ T Cell Responsiveness in the Tumor‐bearing State and Its Recovery in in vitro Culture Free of Tumor Burden

H. Fujiwara, T. Hamaoka, J. Zou, 1993, Japanese journal of cancer research : Gann.

Monoclonal antibodies to Pgp-1/CD44 block lympho-hemopoiesis in long- term bone marrow cultures

T. Hamaoka, K. Medina, P. Kincade, 1990, The Journal of experimental medicine.

A novel function of Valpha14+CD4+NKT cells: stimulation of IL-12 production by antigen-presenting cells in the innate immune system.

H. Fujiwara, M. Taniguchi, H. Ahn, 1999, Journal of immunology.

B cells regulate CD40 ligand-induced IL-12 production in antigen-presenting cells (APC) during T cell/APC interactions.

S. Maruo, M. Oh‐hora, S. Ono, 1997, Journal of immunology.

Transforming Growth Factor‐β CD4+ T cells Tumor‐bearing state Immunosuppression Enhanced Production of TGF‐β and a Progressive Increase in TGF‐β Susceptibility of Anti‐tumor CD4+ T Cell Function

J. Zou, S. Ono, T. Nagata, 1993, Japanese journal of cancer research : Gann.

A role for CD9 molecules in T cell activation

K. Abe, H. Fujiwara, C. Wood, 1996, The Journal of experimental medicine.

Enhanced induction of antitumor T-cell responses by cytotoxic T lymphocyte-associated molecule-4 blockade: the effect is manifested only at the restricted tumor-bearing stages.

J. Zou, S. Ono, R. Wijesuriya, 1997, Cancer research.