H. Chan

发表

Characterization of high molecular weight FK-506 binding activities reveals a novel FK-506-binding protein as well as a protein complex.

N. Sigal, R. Kincaid, M. Martin, 1992, The Journal of biological chemistry.

Structural basis for selectivity of a small molecule, S1-binding, submicromolar inhibitor of urokinase-type plasminogen activator.

B. Katz, R. Mackman, C. Luong, 2000, Chemistry & biology.

Expression cloning and characterization of human 17 beta-hydroxysteroid dehydrogenase type 2, a microsomal enzyme possessing 20 alpha-hydroxysteroid dehydrogenase activity.

K. O. Elliston, L. Wu, W. Geissler, 1993, The Journal of biological chemistry.

Discovery and Optimization of DNA Gyrase and Topoisomerase IV Inhibitors with Potent Activity against Fluoroquinolone-Resistant Gram-Positive Bacteria.

Sarah L. Williams, D. Bussiere, X. Ling, 2021, Journal of medicinal chemistry.

FK-506-binding protein: three-dimensional structure of the complex with the antagonist L-685,818.

J. Springer, J. Hermes, G. Wiederrecht, 1994, The Journal of biological chemistry.

Stabilization of the FK506 binding protein by ligand binding.

G. Sanyal, D. Volkin, H. Chan, 1991, Biochemical and Biophysical Research Communications - BBRC.

Potent inhibition of serine proteases by heterocyclic sulfide derivatives of 1,2,5-thiadiazolidin-3-one 1,1 dioxide.

W. Groutas, R. Kuang, H. Chan, 2000, Bioorganic & medicinal chemistry.

Discovery of a potent small-molecule antagonist of inhibitor of apoptosis (IAP) proteins and clinical candidate for the treatment of cancer (GDC-0152).

Zhaoyang Wen, Brigitte Maurer, Vickie Tsui, 2012, Journal of medicinal chemistry.

Inhibition of serine proteases by functionalized sulfonamides coupled to the 1,2,5-thiadiazolidin-3-one 1,1 dioxide scaffold.

W. Groutas, S. Ruan, R. Kuang, 2001, Bioorganic & medicinal chemistry.

Mechanism-Based Inhibition of Human Steroid 5α-Reductase by Finasteride: Enzyme-Catalyzed Formation of NADP−Dihydrofinasteride, a Potent Bisubstrate Analog Inhibitor

R. Myers, M. Garcia-Calvo, J. Kozarich, 1996 .

Escherichia coli leader peptidase: production of an active form lacking a requirement for detergent and development of peptide substrates.

C. Wilson, P. Griffin, H. Chan, 1993, Archives of biochemistry and biophysics.

Improved calcineurin inhibition by yeast FKBP12-drug complexes. Crystallographic and functional analysis.

J J Burbaum, H K Chan, J. W. Becker, 1993, The Journal of biological chemistry.

Human fibroblast stromelysin catalytic domain: expression, purification, and characterization of a C-terminally truncated form.

H K Chan, J. Hermes, W. Hagmann, 1991, Biochemistry.

Intriguing structure-activity relations underlie the potent inhibition of HIV protease by norstatine-based peptides.

T. Tam, C. Bach, A. Castelhano, 1992, Journal of medicinal chemistry.