H. Nakanishi

发表

Small G-protein networks: their crosstalk and signal cascades.

T Matozaki, T. Matozaki, Y. Takai, 2000, Cellular signalling.

Roles of nectins in cell adhesion, migration and polarization

Y. Takai, H. Nakanishi, 2004, Biological chemistry.

Ponsin/SH3P12: An l-Afadin– and Vinculin-binding Protein Localized at Cell–Cell and Cell–Matrix Adherens Junctions

Y. Takai, A. Mizoguchi, H. Nakanishi, 1999, The Journal of cell biology.

Antagonistic and agonistic effects of an extracellular fragment of nectin on formation of E‐cadherin‐based cell‐cell adhesion

K. Irie, Y. Takai, T. Honda, 2003, Genes to cells : devoted to molecular & cellular mechanisms.

Requirement of Interaction of Nectin-1α/HveC with Afadin for Efficient Cell-Cell Spread of Herpes Simplex Virus Type 1

K. Yamanishi, T. Sakisaka, H. Nakanishi, 2001, Journal of Virology.

Spread of Herpes Simplex Virus Type 1 / HveC with Afadin for Efficient Cell-Cell α Requirement of Interaction of Nectin-1

Y. Takai, K. Yamanishi, T. Sakisaka, 2001 .

Involvement of nectin in the localization of junctional adhesion molecule at tight junctions

K. Irie, T. Kita, Y. Takai, 2002, Oncogene.

Ectodomain shedding of nectin-1α by SF/HGF and TPA in MDCK cells

K. Irie, Y. Takai, T. Sakisaka, 2002 .

Expression patterns of nectins and afadin during epithelial remodeling in the mouse embryo

Y. Takai, N. Okabe, H. Nakanishi, 2004, Developmental dynamics : an official publication of the American Association of Anatomists.

T. Sasaki, Y. Takai, T. Sakisaka, 1999, Genes to cells : devoted to molecular & cellular mechanisms.

A novel rabconnectin‐3‐binding protein that directly binds a GDP/GTP exchange protein for Rab3A small G protein implicated in Ca2+‐dependent exocytosis of neurotransmitter

Y. Takai, T. Sakisaka, H. Kawabe, 2003, Genes to cells : devoted to molecular & cellular mechanisms.

Rab3A Small G Protein and Its Regulators in Neurotransmitter Release and Synaptic Plasticity

J. Miyoshi, Y. Takai, Takuya Sasaki, 2002 .

Isolation of regulatory proteins for the Rab3 subfamily GTPases.

Y. Takai, Takuya Sasaki, H. Nakanishi, 2002, Methods in molecular biology.

Rabconnectin-3, a Novel Protein That Binds Both GDP/GTP Exchange Protein and GTPase-activating Protein for Rab3 Small G Protein Family*

Y. Takai, H. Kawabe, M. Takeuchi, 2002, The Journal of Biological Chemistry.

Purification and properties of Rab3 GDP/GTP exchange protein.

Y. Takai, H. Nakanishi, 2001, Methods in enzymology.

Localization of the Rab3 Small G Protein Regulators in Nerve Terminals and Their Involvement in Ca2+-dependent Exocytosis*

M. Wada, Takuya Sasaki, H. Nakanishi, 1998, The Journal of Biological Chemistry.

Purification and properties of Rab3A.

Y. Takai, A. Kikuchi, H. Nakanishi, 1995, Methods in enzymology.

Contacts between the commissural axons and the floor plate cells are mediated by nectins.

F. Murakami, H. Katsumaru, Y. Takai, 2004, Developmental biology.

A calcium‐protease activator associated with brain microsomal‐insoluble elements

Y. Nishizuka, Y. Takeyama, H. Nakanishi, 1986, FEBS letters.

Rab3A-rabphilin-3A system in neurotransmitter release.

T. Sasaki, Y. Takai, H. Shirataki, 1997, Advances in second messenger and phosphoprotein research.

A novel function of theC‐terminal lipid moieties of Rab3A small G protein implicated in Ca2+‐dependent exocytosis — inhibition of interaction with GTP and reduction of this inhibition by phospholipid

T. Yamamoto, Y. Takai, Y. Fujita, 1997, Genes to cells : devoted to molecular & cellular mechanisms.

Physical and Functional Interaction of Rabphilin-3A with α-Actinin*

T. Sasaki, Y. Takai, M. Kato, 1996, Journal of Biological Chemistry.

Isolation and Characterization of a GTPase Activating Protein Specific for the Rab3 Subfamily of Small G Proteins*

T. Sasaki, K. Fukui, Y. Takai, 1997, The Journal of Biological Chemistry.

Afadin: A key molecule essential for structural organization of cell-cell junctions of polarized epithelia during embryogenesis.

S. Nishikawa, J. Miyoshi, Y. Takai, 1999, The Journal of cell biology.

Purification and characterization of a novel GTP-binding protein with a Mr value of 24,000 from rat liver.

Y. Takai, Y. Takeyama, H. Ohyanagi, 1990, Biochemical and biophysical research communications.

Frabin and other related Cdc42-specific guanine nucleotide exchange factors couple the actin cytoskeleton with the plasma membrane

Y. Takai, H. Nakanishi, 2008, Journal of cellular and molecular medicine.

Different functions of Smg GDP dissociation stimulator and mammalian counterpart of yeast Cdc25.

K. Kaibuchi, Y. Takai, H. Nakanishi, 1994, The Journal of biological chemistry.

Kinetic properties of Ash/Grb2-interacting GDP/GTP exchange protein.

K. Miura, T. Takenawa, K. Kaibuchi, 1994, Biochemical and Biophysical Research Communications - BBRC.

alpha-catenin-independent recruitment of ZO-1 to nectin-based cell-cell adhesion sites through afadin.

K. Irie, M. Monden, K. Tachibana, 2001, Molecular biology of the cell.

SGIP1α Is an Endocytic Protein That Directly Interacts with Phospholipids and Eps15*

T. Takenawa, Hideyuki Yamamoto, S. Suetsugu, 2007, Journal of Biological Chemistry.

Roles of Cell-Cell Adhesion-dependent Tyrosine Phosphorylation of Gab-1*

K. Tachibana, T. Matozaki, A. Kodama, 2001, The Journal of Biological Chemistry.

Cast: a novel protein of the cytomatrix at the active zone of synapses that forms a ternary complex with RIM1 and munc13-1.

Y. Takai, M. Takeuchi, H. Nakanishi, 2002, The Journal of cell biology.

POSSIBLE ROLES OF INOSITOL PHOSPHOLIPIDS IN CELL SURFACE SIGNAL TRANSDUCTION IN NEURONAL TISSUES

Y. Nishizuka, U. Kikkawa, H. Nakanishi, 1986 .

Role of nectin in organization of tight junctions in epithelial cells

K. Irie, Y. Takai, T. Honda, 2002, Genes to cells : devoted to molecular & cellular mechanisms.

Activation of cellular protein kinase C and mode of inhibitory action of phospholipid-interacting compounds.

Y. Nishizuka, Y. Takeyama, H. Nakanishi, 1985, Biochemical and biophysical research communications.

Purification and properties of Rac2 from human leukemia cells.

Y. Takai, T. Mizuno, H. Nakanishi, 1995, Methods in enzymology.

Effects of various spacers between biotin and the phospholipid headgroup on immobilization and sedimentation of biotinylated phospholipid-containing liposomes facilitated by avidin–biotin interactions

H. Nakanishi, Yasuhisa Sakamoto, Kazuaki Umeda, 2017, Journal of biochemistry.

Different behavior of l-Afadin and Neurabin-II during the formation and destruction of cell – cell adherens junction

Y. Takai, T. Sakisaka, H. Nakanishi, 1999, Oncogene.

The expression of nectin‐1α in normal human skin and various skin tumours

A. Utani, Y. Takai, Y. Nakamura, 2003 .

Restoration of E-cadherin-based cell–cell adhesion by overexpression of nectin in HSC-39 cells, a human signet ring cell gastric cancer cell line

M. Monden, M. Takeichi, K. Yanagihara, 2002, Oncogene.

Cell-cell adhesion-mediated tyrosine phosphorylation of nectin-2δ, an immunoglobulin-like cell adhesion molecule at adherens junctions

T. Matozaki, Y. Takai, H. Kawabe, 2000, Oncogene.

Rat brain and liver soluble phospholipase C: resolution of two forms with different requirements for calcium.

Y. Nishizuka, U. Kikkawa, H. Nakanishi, 1985, Biochemical and biophysical research communications.

Nectin Couples Cell-Cell Adhesion and the Actin Scaffold at Heterotypic Testicular Junctions

K. Irie, E. Wimmer, H. Ohta, 2002, Current Biology.

Neurabin-II/Spinophilin AN ACTIN FILAMENT-BINDING PROTEIN WITH ONE PDZ DOMAIN LOCALIZED AT CADHERIN-BASED CELL-CELL ADHESION SITES*

Y. Hata, Y. Takai, A. Mizoguchi, 1998 .

Mode of stimulatory action of deoxycholate in signal transduction system of isolated rat pancreatic acini.

Y. Takai, Y. Takeyama, H. Ohyanagi, 1990, Biochemical and biophysical research communications.

Mode of inhibitory action of cholecystokinin in amylase release from isolated rat pancreatic acini--inhibition of secretory process post to protein kinase C-calcium ion systems.

Y. Takai, A. Kikuchi, Y. Takeyama, 1988, Biochemical and biophysical research communications.

Nectin and afadin: novel organizers of intercellular junctions

Y. Takai, H. Nakanishi, 2003, Journal of Cell Science.

Enhancement of secretagogue-induced phosphoinositide turnover and amylase secretion by bile acids in isolated rat pancreatic acini.

K. Kaibuchi, Y. Takai, Y. Takeyama, 1986, The Journal of clinical investigation.

Isolation and characterization of a novel actin filament-binding protein from Saccharomyces cerevisiae

Y. Takai, H. Imamura, K. Hotta, 1998, Oncogene.

Nexilin: A Novel Actin Filament-binding Protein Localized at Cell–Matrix Adherens Junction

Y. Takai, H. Nakanishi, T. Ohtsuka, 1998, The Journal of cell biology.

Rab3A small GTP‐binding protein in Ca2+‐dependent exocytosis

H. Shirataki, Takuya Sasaki, H. Nakanishi, 1996, Genes to cells : devoted to molecular & cellular mechanisms.

Two Cell Adhesion Molecules, Nectin and Cadherin, Interact through Their Cytoplasmic Domain–Associated Proteins

K. Tachibana, Y. Takai, Yasunori Yamamoto, 2000, The Journal of cell biology.

Interaction of Nectin with Afadin Is Necessary for Its Clustering at Cell-Cell Contact Sites but Not for Itscis Dimerization or trans Interaction*

K. Tachibana, H. Nakanishi, Kenichi Takahashi, 2000, The Journal of Biological Chemistry.

Activation of the zeta isozyme of protein kinase C by phosphatidylinositol 3,4,5-trisphosphate.

J. Exton, H. Nakanishi, K. Brewer, 1993, The Journal of biological chemistry.

Regulation of Ras and Rho small G proteins by SHP‐2

M. Ichihashi, K. Tachibana, T. Matozaki, 2001, Genes to cells : devoted to molecular & cellular mechanisms.

Studies on the phosphorylation of myelin basic protein by protein kinase C and adenosine 3':5'-monophosphate-dependent protein kinase.

Y. Nishizuka, Y. Takeyama, H. Nakanishi, 1985, The Journal of biological chemistry.

Differential Activation of the Luteinizing Hormone β-Subunit Promoter by Activin and Gonadotropin-Releasing Hormone: A Role for the Mitogen-Activated Protein Kinase Signaling Pathway in LβT2 Gonadotrophs1

Hideyuki Yamamoto, E. Miyamoto, H. Kanasaki, 2004, Biology of reproduction.

A putative GDP–GTP exchange factor is required for development of the excretory cell in Caenorhabditis elegans

D. Hall, Kunihiro Matsumoto, N. Hisamoto, 2001, EMBO reports.

Comparison of kinetic properties between two mammalian ras p21 GDP/GTP exchange proteins, ras guanine nucleotide-releasing factor and smg GDP dissociation stimulation.

S. Kuroda, K. Kaibuchi, Y. Takai, 1993, The Journal of biological chemistry.

Identification and characterization of the novel centrosomal protein centlein.

H. Ihn, H. Nakanishi, Kazuaki Umeda, 2008, Biochemical and biophysical research communications.

Afadin: A Novel Actin Filament–binding Protein with One PDZ Domain Localized at Cadherin-based Cell-to-Cell Adherens Junction

M. Itoh, Y. Matsuda, Y. Takai, 1997, The Journal of cell biology.

Isolation and Characterization of a GDP/GTP Exchange Protein Specific for the Rab3 Subfamily Small G Proteins*

Y. Takai, Y. Matsuura, M. Wada, 1997, The Journal of Biological Chemistry.

Nectin/PRR: An Immunoglobulin-like Cell Adhesion Molecule Recruited to Cadherin-based Adherens Junctions through Interaction with Afadin, a PDZ Domain–containing Protein

A. Nomoto, Y. Takai, A. Mizoguchi, 1999, The Journal of cell biology.

Neurabin: A Novel Neural Tissue–specific Actin Filament–binding Protein Involved in Neurite Formation

Y. Takai, A. Mizoguchi, Y. Matsuura, 1997, The Journal of cell biology.

Rho as a regulator of the cytoskeleton.

T. Sasaki, K. Tanaka, Y. Takai, 1995, Trends in biochemical sciences.

Synaptic PDZ domain-containing proteins

Y. Hata, Y. Takai, H. Nakanishi, 1998, Neuroscience Research.

Purification and characterization of the zeta isoform of protein kinase C from bovine kidney.

J. Exton, H. Nakanishi, 1992, The Journal of biological chemistry.

Nectin-3, a New Member of Immunoglobulin-like Cell Adhesion Molecules That Shows Homophilic and Heterophilic Cell-Cell Adhesion Activities*

K. Tachibana, H. Nakanishi, Kenichi Takahashi, 2000, The Journal of Biological Chemistry.

Role of the second immunoglobulin-like loop of nectin in cell-cell adhesion.

K. Irie, Y. Takai, T. Honda, 2002, Biochemical and biophysical research communications.

Map7/7D1 and Dvl form a feedback loop that facilitates microtubule remodeling and Wnt5a signaling

T. Uemura, A. Nakamura, A. Kikuchi, 2018, EMBO reports.

Neurabin-II/Spinophilin

Y. Hata, K. Hirao, Y Takai, 1998, The Journal of Biological Chemistry.

Role of nectin in formation of E-cadherin-based adherens junctions in keratinocytes: analysis with the N-cadherin dominant negative mutant.

Y. Takai, N. Okabe, H. Nakanishi, 2003, Molecular biology of the cell.

Pilt, a Novel Peripheral Membrane Protein at Tight Junctions in Epithelial Cells*

M. Asada, Y. Takai, H. Kawabe, 2001, The Journal of Biological Chemistry.

Association of Frabin with the Actin Cytoskeleton Is Essential for Microspike Formation through Activation of Cdc42 Small G Protein*

Y. Matsuura, I. Hotta, M. Umikawa, 1999, The Journal of Biological Chemistry.

Frabin, a Novel FGD1-related Actin Filament-binding Protein Capable of Changing Cell Shape and Activating c-Jun N-terminal Kinase*

H. Nakanishi, K. Mandai, A. Satoh, 1998, The Journal of Biological Chemistry.

Localization of mLin-7 at nectin-based cell–cell junctions

Y. Takai, Yasunori Yamamoto, T. Hoshino, 2002, Oncogene.

Characterization of the EFC/F‐BAR domain protein, FCHO2

Shiro Suetsugu, T. Takenawa, S. Suetsugu, 2011, Genes to cells : devoted to molecular & cellular mechanisms.

Rho Family Gtpase Cdc42 Is Essential for the Actin-Based Motility of Shigella in Mammalian Cells

C. Sasakawa, T. Takenawa, Y. Takai, 2000, The Journal of experimental medicine.

Nectin: an adhesion molecule involved in formation of synapses.

Y. Takai, A. Mizoguchi, T. Tsutsumi, 2002, The Journal of cell biology.

Activation of Nedd4L Ubiquitin Ligase by FCHO2-generated Membrane Curvature

S. Suetsugu, H. Nakanishi, Yasuhisa Sakamoto, 2022, bioRxiv.

Mass spectrometric analysis of microtubule co‐sedimented proteins from rat brain

N. Araki, K. Makino, H. Nakanishi, 2008, Genes to cells : devoted to molecular & cellular mechanisms.

Cast

Toshihisa Ohtsuka, Yoshimi Takai, Y. Takai, 2002, The Journal of Cell Biology.

Map7D2 and Map7D1 facilitate microtubule stabilization through distinct mechanisms in neuronal cells

Hideyuki Yamamoto, K. Shimamura, K. Ishiguro, 2022, Life Science Alliance.

Interaction of rat lin-10 with brain-enriched F-actin-binding protein, neurabin-II/spinophilin.

Y. Takai, M. Irie, Y. Hata, 1998, Biochemical and biophysical research communications.

Two actions of frabin: direct activation of Cdc42 and indirect activation of Rac

Y. Ono, Y. Takai, H. Nakanishi, 2000, Oncogene.

Association of frabin with specific actin and membrane structures

M. Monden, Yongman Kim, S. Itoh, 2002, Genes to cells : devoted to molecular & cellular mechanisms.

Gonadotropin-Releasing Hormone. A Role for the Mitogen-Activated Protein Kinase 2 Signaling Pathway in LβT2 Gonadotrope Cells 1 3

Hideyuki Yamamoto, E. Miyamoto, H. Kanasaki, 2003 .

Cooperation of Cdc42 small G protein-activating and actin filament-binding activities of frabin in microspike formation

K. Tachibana, Y. Takai, H. Nakanishi, 2001, Oncogene.

The expression of nectin-1alpha in normal human skin and various skin tumours.

A. Utani, Y. Takai, Y. Nakamura, 2003, The British journal of dermatology.

Nectin

Y. Takai, A. Mizoguchi, T. Tsutsumi, 2002, Journal of Cell Biology.

Localization of l‐afadin at puncta adhaerentia‐like junctions between the mossy fiber terminals and the dendritic trunks of pyramidal cells in the adult mouse hippocampus

K. Kimura, H. Nakanishi, K. Mandai, 2000, The Journal of comparative neurology.

Regulation of neurabin I interaction with protein phosphatase 1 by phosphorylation.

P. Greengard, A. Nairn, H. Hemmings, 1999, Biochemistry.

Possible roles of protein kinase C in signal transduction in nervous tissues.

Y. Nishizuka, C. Tanaka, U. Kikkawa, 1986, Progress in brain research.

Association of ASIP/mPAR‐3 with adherens junctions of mouse neuroepithelial cells

S. Hirai, Y. Takai, S. Ohno, 2002, Developmental dynamics : an official publication of the American Association of Anatomists.

Identification of splicing variants of Frabin with partly different functions and tissue distribution.

S. Itoh, Y. Takai, H. Nakanishi, 2001, Biochemical and biophysical research communications.

Ectodomain shedding of nectin-1alpha by SF/HGF and TPA in MDCK cells.

K. Irie, Y. Takai, T. Sakisaka, 2002, Biochemical and biophysical research communications.

Rho small G protein and cytoskeletal control.

T. Sasaki, K. Kaibuchi, Y. Takai, 1994, Princess Takamatsu symposia.

Ponsin/SH3P12: An l-Afadin– and Vinculin-binding Protein Localized at Cell–Cell and Cell–Matrix Adherens Junctions

Y. Takai, A. Mizoguchi, H. Nakanishi, 1999, The Journal of cell biology.

Afadin: A Novel Actin Filament–binding Protein with One PDZ Domain Localized at Cadherin-based Cell-to-Cell Adherens Junction

M. Itoh, Y. Matsuda, Y. Takai, 1997, The Journal of cell biology.

Characterization of the EFC/F‐BAR domain protein, FCHO2

T. Takenawa, S. Suetsugu, H. Nakanishi, 2011, Genes to cells : devoted to molecular & cellular mechanisms.