S. Kawabata

发表

Genome sequence of an M3 strain of Streptococcus pyogenes reveals a large-scale genomic rearrangement in invasive strains and new insights into phage evolution.

Masahira Hattori, Teruo Yasunaga, Ichiro Nakagawa, 2003, Genome research.

The common mucosal immune system for the reproductive tract: basic principles applied toward an AIDS vaccine

Christopher J. Miller, L. Bergmeier, T. Lehner, 1995 .

Inflammatory Immune Responses by Water-insoluble α-glucans

S. Hamada, S. Okamoto, S. Kawabata, 2007 .

Vaccination with formalin-inactivated influenza vaccine protects mice against lethal influenza Streptococcus pyogenes superinfection.

S. Hamada, Y. Okuno, S. Okamoto, 2004, Vaccine.

Recombinant Helicobacter pylori urease activates primary mucosal macrophages.

H. Kiyono, P. D. Smith, P. Harris, 1998, The Journal of infectious diseases.

Streptococcus sanguinis induces neutrophil cell death by production of hydrogen peroxide

S. Wada, M. Yamaguchi, M. Nakata, 2017, PloS one.

Injection of Dental Pulp Stem Cells Promotes Healing of Damaged Bladder Tissue in a Rat Model of Chemically Induced Cystitis

M. Nakashima, Y. Funahashi, M. Yamaguchi, 2016, Cell transplantation.

Surface Pre-Reacted Glass Filler Contributes to Tertiary Dentin Formation through a Mechanism Different Than That of Hydraulic Calcium-Silicate Cement

Masakatsu Watanabe, D. Okuzaki, M. Mizuhira, 2019, Journal of clinical medicine.

PfbA, a Novel Plasmin- and Fibronectin-binding Protein of Streptococcus pneumoniae, Contributes to Fibronectin-dependent Adhesion and Antiphagocytosis*

S. Hamada, M. Yamaguchi, S. Kawabata, 2008, Journal of Biological Chemistry.

Streptococcus pneumoniae surface adhesin PfbA and its interaction with erythrocytes and hemoglobin.

K. Ponnuraj, M. Yamaguchi, S. Kawabata, 2018, International journal of biological macromolecules.

Molecular and genomic characterization of pathogenic traits of group A Streptococcus pyogenes

S. Hamada, I. Nakagawa, S. Kawabata, 2015, Proceedings of the Japan Academy. Series B, Physical and biological sciences.

Cytochrome c‐mediated caspase‐9 activation triggers apoptosis in Streptococcus pyogenes‐infected epithelial cells

S. Hamada, M. Nakata, S. Kawabata, 2001, Cellular microbiology.

Functional Differences among FimA Variants of Porphyromonas gingivalis and Their Effects on Adhesion to and Invasion of Human Epithelial Cells

S. Hamada, I. Nakagawa, A. Amano, 2002, Infection and Immunity.

Distribution and Molecular Characterization ofPorphyromonas gingivalis Carrying a New Type offimA Gene

S. Hamada, I. Nakagawa, A. Amano, 2000, Journal of Clinical Microbiology.

Distribution and molecular characterization of Porphyromonas gingivalis carrying a new type of fimA gene.

S. Hamada, I. Nakagawa, A. Amano, 2001, Journal of clinical microbiology.

Streptococcus pyogenes Phospholipase A2 Induces the Expression of Adhesion Molecules on Human Umbilical Vein Endothelial Cells and Aorta of Mice

Mie Kurosawa, M. Oda, T. Maekawa, 2017, Front. Cell. Infect. Microbiol..

Comparative genomic analyses of Streptococcus mutans provide insights into chromosomal shuffling and species-specific content

M. Hattori, K. Kurokawa, K. Nakai, 2009, BMC Genomics.

Distribution of emm genotypes and superantigen genes of Streptococcus pyogenes isolated in Japan, 1994–9

S. Hamada, I. Nakagawa, I. Morisaki, 2002, Epidemiology and Infection.

Pneumococcal DNA-binding proteins released through autolysis induce the production of proinflammatory cytokines via toll-like receptor 4.

M. Oda, K. Tabeta, A. Saitoh, 2018, Cellular immunology.

Streptococcus pyogenes CAMP factor promotes bacterial adhesion and invasion in pharyngeal epithelial cells without serum via PI3K/Akt signaling pathway.

I. Saitoh, H. Hayasaki, Mie Kurosawa, 2017, Microbes and infection.

Effects of Extracellular pH on Dental Pulp Cells In Vitro.

M. Nakashima, M. Yamaguchi, M. Gotoh, 2016, Journal of endodontics.

Pneumococcal BgaA Promotes Host Organ Bleeding and Coagulation in a Mouse Sepsis Model

D. Okuzaki, D. Motooka, M. Yamaguchi, 2022, Frontiers in Cellular and Infection Microbiology.

Group A Streptococcal Cysteine Protease Degrades C3 (C3b) and Contributes to Evasion of Innate Immunity*

S. Hamada, M. Yamaguchi, S. Kawabata, 2008, Journal of Biological Chemistry.

Epidemiological characterization of Streptococcus pyogenes isolated from patients with multiple onsets of pharyngitis.

H. Sakata, Y. Maeda, K. Ikebe, 2011, FEMS microbiology letters.

Systemic and Mucosal Immunizations with Fibronectin-Binding Protein FBP54 Induce Protective Immune Responses against Streptococcus pyogenes Challenge in Mice

S. Hamada, I. Nakagawa, K. Totsuka, 2001, Infection and Immunity.

Transcriptomic profiling of Streptococcus pyogenes M1T1 strain in a mouse model of necrotizing fasciitis

D. Okuzaki, D. Motooka, H. Hamamoto, 2019, bioRxiv.

Proapoptotic Effect of Proteolytic Activation of Matrix Metalloproteinases by Streptococcus pyogenes Thiol Proteinase (Streptococcus Pyrogenic Exotoxin B)

H. Maeda, S. Hamada, T. Akaike, 2004, Infection and Immunity.

Assembly Mechanism of FCT Region Type 1 Pili in Serotype M6 Streptococcus pyogenes*

S. Hamada, B. Kreikemeyer, A. Podbielski, 2011, The Journal of Biological Chemistry.

, Masanobu Nakata , Contributes to Bacterial Translocation Cleaves Epithelial Junctions and Group A Streptococcal Cysteine Protease

M. Nakata, S. Kawabata, Y. Terao, 2013 .

Degradation of bradykinin by a metalloendopeptidase from Streptococcus pyogenes.

H. Maeda, S. Hamada, Y. Miyamoto, 2016, Journal of oral biosciences.

Erratum: Group A Streptococcus exploits human plasminogen for bacterial translocation across epithelial barrier via tricellular tight junctions

M. Yamaguchi, M. Nakata, S. Kawabata, 2016, Scientific Reports.

Protective immunity against Streptococcus pyogenes challenge in mice after immunization with fibronectin-binding protein.

S. Hamada, K. Kataoka, S. Okamoto, 2005, The Journal of infectious diseases.

Capsular hyaluronic acid of group A streptococci hampers their invasion into human pharyngeal epithelial cells.

H. Kuwata, S. Hamada, I. Nakagawa, 1999, Microbial pathogenesis.

Streptococcal Cysteine Protease-Mediated Cleavage of Desmogleins Is Involved in the Pathogenesis of Cutaneous Infection

M. Yamaguchi, H. Matsue, Yuumi Nakamura, 2018, Front. Cell. Infect. Microbiol..

Lysine and Threonine Biosynthesis from Aspartate Contributes to Staphylococcus aureus Growth in Calf Serum

M. Yamaguchi, S. Kawabata, H. Komatsuzawa, 2016, Applied and Environmental Microbiology.

Mode of Expression and Functional Characterization of FCT-3 Pilus Region-Encoded Proteins in Streptococcus pyogenes Serotype M49

B. Kreikemeyer, A. Podbielski, L. Jonas, 2008, Infection and Immunity.

S-carboxymethylcysteine inhibits adherence of Streptococcus pneumoniae to human alveolar epithelial cells.

M. Yamaguchi, M. Nakata, S. Kawabata, 2012, Journal of medical microbiology.

Administration of Superantigens Protects Mice from Lethal Listeria monocytogenes Infection by Enhancing Cytotoxic T Cells

S. Hamada, S. Okamoto, S. Kawabata, 2001, Infection and Immunity.

Hydrogen Peroxide Contributes to the Epithelial Cell Death Induced by the Oral Mitis Group of Streptococci

H. Kuwata, M. Nakata, N. Okahashi, 2014, PloS one.

Inhibitory Effects of Oenothera biennis (Evening Primrose) Seed Extract on Streptococcus mutans and S. mutans-Induced Dental Caries in Rats

S. Kawabata, T. Ooshima, M. Matsumoto-Nakano, 2011, Caries Research.

Glucosyltransferases of Mutans Streptococci

S. Hamada, Takaharu Tanaka, H. Ono, 2022 .

Mucosal immune features to phosphorylcholine by nasal Flt3 ligand cDNA-based vaccination.

Masafumi Yamamoto, K. Fujihashi, K. Kataoka, 2011, Vaccine.

Intraepithelial lymphocytes from villus tip and crypt portions of the murine small intestine show distinct characteristics.

J. Mcghee, H. Kiyono, M. Yamamoto, 1998, Gastroenterology.

A novel alkaline phosphatase-based isolation method allows characterization of intraepithelial lymphocytes from villi tip and crypt regions of murine small intestine.

J. Mcghee, S. Hamada, H. Kiyono, 1997, Biochemical and biophysical research communications.

Water-insoluble α-glucans from Streptococcus sobrinus induce inflammatory immune responses

S. Hamada, S. Okamoto, S. Kawabata, 2007 .

Composition of salivary microbiota in elderly subjects

S. Sasaki, Y. Maeda, K. Ikebe, 2018, Scientific Reports.

Group A Streptococcus Adheres to Pharyngeal Epithelial Cells with Salivary Proline-rich Proteins via GrpE Chaperone Protein*

S. Hamada, I. Morisaki, S. Kawabata, 2012, The Journal of Biological Chemistry.

Nrc of Streptococcus pneumoniae suppresses capsule expression and enhances anti-phagocytosis.

S. Hamada, R. Isoda, S. Yokota, 2009, Biochemical and biophysical research communications.

Streptococcus pyogenes CAMP factor promotes calcium ion uptake in RAW264.7 cells

I. Saitoh, H. Hayasaki, Mie Kurosawa, 2018, Microbiology and immunology.

Pili of oral Streptococcus sanguinis bind to fibronectin and contribute to cell adhesion.

R. Isoda, M. Yamaguchi, T. Hoshino, 2010, Biochemical and biophysical research communications.

Role of Streptococcus sanguinis sortase A in bacterial colonization.

S. Hamada, Toshihito Takahashi, M. Yamaguchi, 2006, Microbes and infection.

Streptococcus pneumoniae Evades Host Cell Phagocytosis and Limits Host Mortality Through Its Cell Wall Anchoring Protein PfbA

M. Yamaguchi, M. Nakata, S. Kawabata, 2019, Frontiers in cellular and infection microbiology.

Neutrophil Elastase Subverts the Immune Response by Cleaving Toll-Like Receptors and Cytokines in Pneumococcal Pneumonia

M. Oda, T. Maekawa, M. Yamaguchi, 2018, Front. Immunol..

Long-term survival of salivary streptococci on dental devices made of ethylene vinyl acetate

Y. Maeda, S. Kawabata, Y. Terao, 2012, International Journal of Oral Science.

Hydrogen Peroxide Produced by Oral Streptococci Induces Macrophage Cell Death

M. Nakata, N. Okahashi, S. Kawabata, 2013, PloS one.

Streptococcus sanguinis induces foam cell formation and cell death of macrophages in association with production of reactive oxygen species.

T. Okinaga, T. Nishihara, M. Nakata, 2011, FEMS microbiology letters.

Silkworm pathogenic bacteria infection model for identification of novel virulence genes

S. Hamada, K. Kurokawa, C. Kaito, 2005, Molecular microbiology.

serotype distribution and antimicrobial susceptibility profile of streptococcus pneumoniae among myanmar children with acute respiratory infection

K. Thant, H. M. Thu, M. Yamaguchi, 2018 .

Pili of oral Streptococcus sanguinis bind to salivary amylase and promote the biofilm formation.

R. Isoda, M. Yamaguchi, M. Nakata, 2011, Microbial pathogenesis.

Mucosal Th1- versus Th2-type responses for antibody- or cell-mediated immunity to simian immunodeficiency virus in rhesus macaques.

T. Lehner, J. Mcghee, H. Kiyono, 1999, The Journal of infectious diseases.

Induction of Th2 cytokine expression for p27-specific IgA B cell responses after targeted lymph node immunization with simian immunodeficiency virus antigens in rhesus macaques.

T. Lehner, J. Mcghee, H. Kiyono, 1998, The Journal of infectious diseases.

Streptococcus pneumoniae Invades Erythrocytes and Utilizes Them to Evade Human Innate Immunity

V. Nizet, A. Yamaguchi, M. Yamaguchi, 2013, PloS one.

Elucidation of independently modulated genes in Streptococcus pyogenes reveals carbon sources that control its expression of hemolytic toxins

Daniel C. Zielinski, Anand V. Sastry, V. Nizet, 2022, bioRxiv.

High mucosal levels of tumor necrosis factor alpha messenger RNA in AIDS-associated cytomegalovirus-induced esophagitis.

H. Kiyono, P. D. Smith, P. Harris, 1998, Gastroenterology.

Identification and characterization of a collagen-binding protein, Cbm, in Streptococcus mutans.

S. Alaluusua, S. Kawabata, R. Nomura, 2012, Molecular oral microbiology.

Infection and pathogenesis of a murine strain of Escherichia coli with genetically introduced Shiga toxin type I operon in conventional mice.

S. Hamada, I. Nakagawa, S. Wakisaka, 2002, Microbial pathogenesis.

α-Enolase of Streptococcus pneumoniae Induces Formation of Neutrophil Extracellular Traps*

S. Hamada, M. Yamaguchi, S. Kawabata, 2012, The Journal of Biological Chemistry.

Nucleotide sequence and molecular characterization of a gene encoding GTP-binding protein from Streptococcus gordonii.

S. Hamada, S. Kawabata, T. Andoh, 1997, FEMS microbiology letters.

Streptococcus pneumoniae evades host cell phagocytosis and limits host mortality through its cell wall anchoring protein PfbA

M. Yamaguchi, M. Nakata, S. Kawabata, 2019, bioRxiv.

Interleukin 2 (IL-2) and interleukin 7 (IL-7) reciprocally induce IL-7 and IL-2 receptors on gamma delta T-cell receptor-positive intraepithelial lymphocytes.

S. Nishikawa, J. Mcghee, H. Kiyono, 1996, Proceedings of the National Academy of Sciences of the United States of America.

The Group A Streptococcus Interleukin-8 Protease SpyCEP Promotes Bacterial Intracellular Survival by Evasion of Autophagy

V. Nizet, M. Rohde, G. S. Chhatwal, 2022, Infectious microbes & diseases.

Contributions of Three Glucosyltransferases to Sucrose-dependent Adherence of Streptococcus mutans

T. Fujiwara, T. Hoshino, S. Kawabata, 2001, Journal of dental research.

Genetic Characterization of Streptococcus pyogenes emm89 Strains Isolated in Japan From 2011 to 2019

T. Miyoshi‐Akiyama, N. Nakanishi, M. Yamaguchi, 2020, bioRxiv.

Oral-Nasopharyngeal Dendritic Cells Mediate T Cell-Independent IgA Class Switching on B-1 B Cells

K. Fujihashi, S. Sekine, K. Kataoka, 2011, PloS one.

Secondary streptococcal infection following influenza

M. Nakata, N. Okahashi, S. Kawabata, 2022, Microbiology and immunology.

Intraepithelial γδ T Cell and Epithelial Cell Interactions in the Mucosal Immune System

J. Mcghee, H. Kiyono, Masafumi Yamamoto, 1996 .

Human interleukin-12 enhances interferon-gamma-producing influenza-specific memory CD8+ cytotoxic T lymphocytes.

R. Couch, J. Mcghee, H. Kiyono, 1999, The Journal of infectious diseases.

Detection of Fibronectin-Binding Proteins of Streptococcus pyogenes Using Ligand Blot Analysis.

M. Nakata, S. Kawabata, 2020, Methods in molecular biology.

Streptococcus pyogenes Infection Induces Septic Arthritis with Increased Production of the Receptor Activator of the NF-κB Ligand

S. Hamada, I. Nakagawa, A. Amano, 2003, Infection and Immunity.

Calcineurin Potentiates the Activation of Procaspase-3 by Accelerating Its Proteolytic Maturation*

S. Kawabata, M. Saeki, Y. Irie, 2007, Journal of Biological Chemistry.

Streptococcal immunoglobulin-binding protein Sib35 exerts stimulatory and mitogenic effects toward mouse B lymphocytes.

S. Hamada, S. Okamoto, S. Kawabata, 2008, FEMS microbiology letters.

Systemic immunization with streptococcal immunoglobulin-binding protein Sib 35 induces protective immunity against group: a Streptococcus challenge in mice.

S. Hamada, S. Okamoto, S. Kawabata, 2005, Vaccine.

Targeted Salivary Gland Immunization with Plasmid DNA Elicits Specific Salivary Immunoglobulin A and G Antibodies and Serum Immunoglobulin G Antibodies in Mice

S. Hamada, I. Nakagawa, T. Fujiwara, 1999, Infection and Immunity.

GP96 Drives Exacerbation of Secondary Bacterial Pneumonia following Influenza A Virus Infection

S. Nagase, M. Yamaguchi, S. Okamoto, 2020, bioRxiv.

Streptococcus oralis Induces Lysosomal Impairment of Macrophages via Bacterial Hydrogen Peroxide

H. Kuwata, M. Nakata, N. Okahashi, 2016, Infection and Immunity.

Functional y6 T-lymphocyte Defect Associated with Human Immunodeficiency Virus Infections

H. Kiyono, B. Bloom, P. Fisch, 2007 .

Inhibitory effect of oolong tea polyphenols on glycosyltransferases of mutans Streptococci

S. Hamada, K. Ogura, H. Ono, 1993, Applied and environmental microbiology.

Synergistic Effects of Streptococcal Glucosyltransferases on Adhesive Biofilm Formation

S. Hamada, T. Fujiwara, S. Kawabata, 2004, Journal of dental research.

Oral passive immunization against dental caries in rats by use of hen egg yolk antibodies specific for cell-associated glucosyltransferase of Streptococcus mutans

S. Hamada, T. Fujiwara, S. Kawabata, 1991, Infection and immunity.

Contribution of Streptococcus pyogenes M87 protein to innate immune resistance and virulence.

V. Nizet, S. Uchiyama, P. Ghosh, 2022, Microbial pathogenesis.

Comparison of trophic factors secreted from human adipose-derived stromal vascular fraction with those from adipose-derived stromal/stem cells in the same individuals.

Y. Funahashi, M. Yamaguchi, M. Gotoh, 2018, Cytotherapy.

Streptococcal H2O2 inhibits IgE-triggered degranulation of RBL-2H3 mast cell/basophil cell line by inducing cell death

H. Kuwata, H. Kataoka, M. Nakata, 2020, PloS one.

Streptococcus pneumoniae Surface Adhesin PfbA Exhibits Host Specificity by Binding to Human Serum Albumin but Not Bovine, Rabbit and Porcine Serum Albumins

K. Ponnuraj, M. Yamaguchi, S. Sankar, 2019, The Protein Journal.

Oral mitis group streptococci: A silent majority in our oral cavity

H. Kuwata, M. Nakata, N. Okahashi, 2022, Microbiology and immunology.

Identification of a new variant of fimA gene of Porphyromonas gingivalis and its distribution in adults and disabled populations with periodontitis.

S. Hamada, I. Nakagawa, S. Kimura, 2002, Journal of periodontal research.

Oral mitis group streptococci reduce infectivity of influenza A virus via acidification and H2O2 production

H. Kuwata, M. Nakata, N. Okahashi, 2022, PloS one.

Fusobacterium nucleatum Envelope Protein FomA Is Immunogenic and Binds to the Salivary Statherin-Derived Peptide

S. Shizukuishi, K. Fujihashi, S. Sekine, 2009, Infection and Immunity.

A model of invasive type of Streptococcus pyogenes infection after intranasal superinfection in influenza A virus-infected mice

S. Hamada, I. Nakagawa, K. Sano, 2004 .

Evolution of Cariogenic Character in Streptococcus mutans: Horizontal Transmission of Glycosyl Hydrolase Family 70 Genes

T. Fujiwara, T. Hoshino, S. Kawabata, 2012, Scientific Reports.

Group A Streptococcal Cysteine Protease Cleaves Epithelial Junctions and Contributes to Bacterial Translocation*

M. Nakata, S. Kawabata, Y. Terao, 2013, The Journal of Biological Chemistry.

Oolong tea polyphenols inhibit experimental dental caries in SPF rats infected with mutans streptococci.

S. Hamada, T. Fujiwara, S. Kawabata, 1993, Caries research.

Studying biofilm formation of mutans streptococci.

S. Hamada, S. Kawabata, 1999, Methods in enzymology.

Effects of selected surfactants on purified glucosyltransferases from mutans streptococci and cellular adherence to smooth surfaces.

M. Torii, S. Hamada, T. Fujiwara, 1993, Journal of medical microbiology.

OralPassive Immunization against Dental Caries inRatsbyUseof HenEggYolkAntibodies Specific forCell-Associated Glucosyltransferase ofStreptococcus mutans

T. Fujiwara, S. Kawabata, T. Minami, 1991 .

Microbiological assessment of effects of clinical mouth rinses on common oral microbes.

Y. Maeda, K. Ikebe, S. Kawabata, 2017, Journal of oral science.

Biochemical and genetic characterization of serologically untypable Streptococcus mutans strains isolated from patients with bacteremia.

S. Hamada, I. Nakagawa, T. Fujiwara, 2001, European journal of oral sciences.

Title Novel Epitopic Region of Glucosyltransferase B from Streptococcusmutans

Kan Saito, T. Fujiwara, T. Hoshino, 2017 .

Novel Epitopic Region of Glucosyltransferase B from Streptococcus mutans

Kan Saito, T. Fujiwara, T. Hoshino, 2011, Clinical and Vaccine Immunology.

The importance of fimbriae in the virulence and ecology of some oral bacteria.

S. Hamada, I. Nakagawa, S. Kimura, 1998, Oral microbiology and immunology.

Performance of a Biodegradable Composite with Hydroxyapatite as a Scaffold in Pulp Tissue Repair

Ryuji Kato, Masakatsu Watanabe, K. Uto, 2020, Polymers.

Molecular cloning of novel Monad binding protein containing tetratricopeptide repeat domains

H. Yatani, H. Egusa, S. Kawabata, 2008, FEBS letters.

Streptococcus pneumoniae surface protein PfbA is a versatile multidomain and multiligand‐binding adhesin employing different binding mechanisms

K. Ponnuraj, M. Yamaguchi, S. Kawabata, 2017, The FEBS journal.

Targeted lymph‐node immunization with whole inactivated simian immunodeficiency virus (SIV) or envelope and core subunit antigen vaccines does not reliably protect rhesus macaques from vaginal challenge with SIVmac251

T. Lehner, J. Mcghee, H. Kiyono, 1998, AIDS.

Deletion and reintroduction of glucosyltransferase genes of Streptococcus mutans and role of their gene products in sucrose dependent cellular adherence.

S. Hamada, Z. Bian, T. Fujiwara, 1996, Microbial Pathogenesis.

Secretion of Functional Salivary Peptide by Streptococcus gordonii Which Inhibits Fimbria-Mediated Adhesion ofPorphyromonas gingivalis

S. Hamada, H. Nagata, S. Shizukuishi, 1999, Infection and Immunity.

Studying Bacterial Adhesion to Tooth Surfaces

S. Hamada, T. Fujiwara, S. Kawabata, 2000 .

Antibacterial activity of hinokitiol against both antibiotic‐resistant and ‐susceptible pathogenic bacteria that predominate in the oral cavity and upper airways

K. Yanagihara, T. Maekawa, S. Kawabata, 2019, Microbiology and immunology.

Molecular and biological characterization of gtf regulation-associated genes in Streptococcus mutans.

S. Hamada, R. Isoda, S. Kawabata, 2009, Oral microbiology and immunology.

Molecular analyses of glucosyltransferase genes among strains of Streptococcus mutans.

S. Hamada, T. Fujiwara, T. Hoshino, 1998, FEMS microbiology letters.

Modification of sucrose dependent cell adherence by deletion and reintroduction of the gtf genes in Streptococcus mutans.

S. Hamada, Z. Bian, T. Fujiwara, 1997, Advances in experimental medicine and biology.

Molecular characterization and expression of the cell-associated glucosyltransferase gene from Streptococcus mutans.

S. Hamada, T. Fujiwara, S. Kawabata, 1992, Biochemical and biophysical research communications.

Composition of salivary microbiota in elderly subjects

S. Sasaki, Y. Maeda, K. Ikebe, 2018, Scientific Reports.

Streptolysin S Contributes to Group A Streptococcal Translocation across an Epithelial Barrier*

M. Nakata, S. Kawabata, Yingji Jin, 2010, The Journal of Biological Chemistry.

Multifunctional Glyceraldehyde-3-phosphate Dehydrogenase of Streptococcus pyogenes Is Essential for Evasion from Neutrophils*

Yutaka Terao, S. Hamada, M. Yamaguchi, 2006, Journal of Biological Chemistry.

Streptococcus pyogenes upregulates arginine catabolism to exert its pathogenesis on the skin surface.

V. Nizet, D. Okuzaki, D. Motooka, 2021, Cell reports.

Streptococcus pyogenes Transcriptome Changes in the Inflammatory Environment of Necrotizing Fasciitis

Daisuke Motooka, Hiroshi Hamamoto, D. Okuzaki, 2019, Applied and Environmental Microbiology.

Transcriptomic profiling of Streptococcus pyogenes M 1 T 1 strain in a mouse model of 2 necrotizing fasciitis 3 4 Short title : S . pyogenes transcriptome in mouse necrotizing fasciitis model 5 6

D. Okuzaki, D. Motooka, H. Hamamoto, 2022 .

Construction of human three-dimensional lung model using layer-by-layer method.

M. Akashi, T. Akagi, S. Kawabata, 2023, Tissue engineering. Part C, Methods.

MicroRNA fragments derived from Streptococcus pyogenes enable activation of neutrophil phagocytosis: in vitro study.

Y. Maeda, K. Ikebe, S. Kawabata, 2013, Microbes and infection.

Group A Streptococcus exploits human plasminogen for bacterial translocation across epithelial barrier via tricellular tight junctions

M. Yamaguchi, M. Nakata, S. Kawabata, 2016, Scientific Reports.

Molecular Interactions of Porphyromonas gingivalisFimbriae with Host Proteins: Kinetic Analyses Based on Surface Plasmon Resonance

S. Hamada, I. Morisaki, A. Amano, 1999, Infection and Immunity.

Molecular and biological characterization of histidine triad protein in group A streptococci.

S. Hamada, S. Okamoto, S. Kawabata, 2008, Microbes and infection.

Functional γδ T-lymphocyte Defect Associated with Human Immunodeficiency Virus Infections

H. Kiyono, Yoshimasa Tanaka, B. Bloom, 1997, Molecular medicine.

Thermosensitive pilus production by FCT type 3 Streptococcus pyogenes controlled by Nra regulator translational efficiency

B. Kreikemeyer, N. Patenge, M. Nakata, 2019, Molecular microbiology.

Influenza A Virus-Infected Hosts Boost an Invasive Type of Streptococcus pyogenes Infection in Mice

S. Hamada, I. Nakagawa, K. Sano, 2003, Journal of Virology.

Functional y 6 T-lymphocyte Defect Associated with Human Immunodeficiency Virus Infections

H. Kiyono, Yoshimasa Tanaka, B. Bloom, 2007 .

Transcriptome analysis and gene expression profiles of early apoptosis‐related genes in Streptococcus pyogenes‐infected epithelial cells

S. Hamada, I. Nakagawa, M. Nakata, 2004, Cellular microbiology.

Biofilm formation or internalization into epithelial cells enable Streptococcus pyogenes to evade antibiotic eradication in patients with pharyngitis.

H. Sakata, Y. Maeda, K. Ikebe, 2011, Microbial pathogenesis.

Streptococcus pyogenes Endopeptidase O Contributes to Evasion from Complement-mediated Bacteriolysis via Binding to Human Complement Factor C1q*

M. Yamaguchi, M. Nakata, S. Kawabata, 2017, The Journal of Biological Chemistry.

Oral immunization with simian immunodeficiency virus p55gag and cholera toxin elicits both mucosal IgA and systemic IgG immune responses in nonhuman primates.

J. Mcghee, H. Kiyono, C. Miller, 1997, Journal of immunology.

Involvement of T6 Pili in Biofilm Formation by Serotype M6 Streptococcus pyogenes

B. Kreikemeyer, A. Podbielski, M. Nakata, 2011, Journal of bacteriology.

Identification of evolutionarily conserved virulence factor by selective pressure analysis of Streptococcus pneumoniae

M. Yamaguchi, M. Nakata, S. Kawabata, 2018, Communications Biology.

Role of BgaA as a Pneumococcal Virulence Factor Elucidated by Molecular Evolutionary Analysis

M. Yamaguchi, N. Uzawa, M. Nakata, 2020, Frontiers in Microbiology.

Zinc metalloproteinase ZmpC suppresses experimental pneumococcal meningitis by inhibiting bacterial invasion of central nervous systems

S. Wada, M. Yamaguchi, M. Nakata, 2017, Virulence.

Molecular Characterization of a Novel Fibronectin-binding Protein of Streptococcus pyogenesStrains Isolated from Toxic Shock-like Syndrome Patients*

S. Hamada, I. Nakagawa, M. Nakata, 2002, The Journal of Biological Chemistry.

Fba, a novel fibronectin‐binding protein from Streptococcus pyogenes, promotes bacterial entry into epithelial cells, and the fba gene is positively transcribed under the Mga regulator

S. Hamada, I. Nakagawa, S. Kawabata, 2001, Molecular microbiology.

Evolutionary inactivation of a sialidase in group B Streptococcus

V. Nizet, S. Uchiyama, A. Lewis, 2016, Scientific Reports.

Biological Evaluation of the Effect of Root Canal Sealers Using a Rat Model

M. Mizuhira, M. Hayashi, S. Kawabata, 2022, Pharmaceutics.

Evaluation of decontamination methods of oral biofilms formed on screw-shaped, rough and machined surface implants: an ex vivo study

M. Wada, Y. Maeda, K. Ikebe, 2020, International journal of implant dentistry.

Inhibitory Effects of Protamines on Proteolytic and Adhesive Activities of Porphyromonas gingivalis

S. Hamada, I. Nakagawa, A. Amano, 1999, Infection and Immunity.

Molecular cloning, sequence and characterization of a novel streptococcal phosphoglycerate dehydrogenase gene.

S. Hamada, S. Kawabata, Y. Terao, 2000, Oral microbiology and immunology.

Unique virulence role of post-translocational chaperone PrsA in shaping Streptococcus pyogenes secretome

D. Gonzalez, M. Yamaguchi, S. Kawabata, 2021, Virulence.

Pleiotropic virulence factor – Streptococcus pyogenes fibronectin‐binding proteins

M. Yamaguchi, S. Kawabata, Y. Terao, 2013, Cellular microbiology.

The Streptococcus pyogenes Serotype M49 Nra-Ralp3 Transcriptional Regulatory Network and Its Control of Virulence Factor Expression from the Novel eno ralp3 epf sagA Pathogenicity Region

M. Glocker, B. Kreikemeyer, A. Podbielski, 2007, Infection and Immunity.

The Streptococcus pyogenes serotype M 49 Nra-Ralp 3 Transcriptional Regulatory Network and its Control on Virulence Factor Expression from the Novel ERES Pathogenicity Region

M. Glocker, B. Kreikemeyer, A. Podbielski, 2007 .

Regulated expression of the Shiga toxin B gene induces apoptosis in mammalian fibroblastic cells

S. Hamada, M. Nakata, S. Kawabata, 1999, Molecular microbiology.

RESULTS Stimulation of Mouse Peritoneal Exudate Macrophages by Water-insoluble

S. Hamada, S. Okamoto, S. Kawabata, 2007 .

Involvement of ribonuclease Y in pilus production by M49 Streptococcus pyogenes strain via modulation of messenger RNA level of transcriptional regulator

B. Kreikemeyer, M. Yamaguchi, N. Uzawa, 2023, Microbiology and immunology.

Infection by Streptococcus pyogenes Induces the Receptor Activator of NF-κB Ligand Expression in Mouse Osteoblastic Cells

S. Hamada, I. Nakagawa, T. Fujiwara, 2003, Infection and Immunity.

The Nasal Dendritic Cell-Targeting Flt3 Ligand as a Safe Adjuvant Elicits Effective Protection against Fatal Pneumococcal Pneumonia

D. Briles, S. Hollingshead, K. Oishi, 2011, Infection and Immunity.

Characterizations of oral microbiota in elderly nursing home residents with diabetes.

S. Sasaki, Y. Maeda, K. Ikebe, 2017, Journal of oral science.

Cysteine Proteinase from Streptococcus pyogenes Enables Evasion of Innate Immunity via Degradation of Complement Factors*

Y. Maeda, K. Ikebe, M. Nakata, 2013, The Journal of Biological Chemistry.

Cell Wall-Anchored Nuclease of Streptococcus sanguinis Contributes to Escape from Neutrophil Extracellular Trap-Mediated Bacteriocidal Activity

S. Hamada, S. Wada, M. Nakata, 2014, PloS one.

Identification of evolutionarily conserved virulence factor by selective pressure analysis of Streptococcus pneumoniae

M. Yamaguchi, M. Nakata, S. Kawabata, 2018, bioRxiv.

Competence-induced protein Ccs4 facilitates pneumococcal invasion into brain tissue and virulence in meningitis

M. Yamaguchi, M. Nakata, S. Kawabata, 2018, Virulence.

Novel Laminin-Binding Protein of Streptococcus pyogenes, Lbp, Is Involved in Adhesion to Epithelial Cells

S. Hamada, I. Nakagawa, S. Kawabata, 2002, Infection and Immunity.

Crystal structure of PfbA, a surface adhesin of Streptococcus pneumoniae, provides hints into its interaction with fibronectin.

K. Ponnuraj, M. Yamaguchi, S. Kawabata, 2014, International journal of biological macromolecules.

The Streptococcus pyogenes Capsule Is Required for Adhesion of Bacteria to Virus-Infected Alveolar Epithelial Cells and Lethal Bacterial-Viral Superinfection

S. Hamada, Y. Okuno, S. Okamoto, 2004, Infection and Immunity.

Respiratory FimA-Specific Secretory IgA Antibodies Upregulated by DC-Targeting Nasal Double DNA Adjuvant Are Essential for Elimination of Porphyromonas gingivalis

K. Fujihashi, Y. Hashimoto, Tatsuro Miyake, 2021, Frontiers in Immunology.

A novel, anchorless streptococcal surface protein that binds to human immunoglobulins.

Ichiro Nakagawa, Yutaka Terao, S. Hamada, 2002, Biochemical and biophysical research communications.

Involvement of T 6 pili in biofilm formation by serotype M 6 Streptococcus 1 pyogenes 2 3 4

B. Kreikemeyer, A. Podbielski, M. Nakata, 2011 .

Gut microbiota-mediated alleviation of dextran sulfate sodium-induced colitis in mice

M. Yamaguchi, S. Kawabata, Eri Ikeda, 2023, bioRxiv.

Distribution and Molecular Characterization ofPorphyromonas gingivalis Carrying a New Type offimA Gene

S. Hamada, A. Amano, S. Kawabata, 2000, Journal of Clinical Microbiology.

A novel streptococcal leucine zipper protein (Lzp) binds to human immunoglobulins.

S. Hamada, S. Okamoto, S. Kawabata, 2008, Biochemical and biophysical research communications.

Streptococcus pneumoniae Evades Host Cell Phagocytosis and Limits Host Mortality Through Its Cell Wall Anchoring Protein PfbA

M. Yamaguchi, M. Nakata, S. Kawabata, 2019, bioRxiv.

Comparative genomic analyses of Streptococcus mutans provide insights into chromosomal shuffling and species-specific content

M. Hattori, K. Kurokawa, K. Nakai, 2009, BMC Genomics.