E. Toth

发表

In vitro screening and structural characterization of inhibitors of the S100B-p53 interaction.

Edwin Pozharski, David J Weber, Andrew Coop, 2010, International journal of high throughput screening.

Structural and Biophysical Characterization of the HCV E1E2 Heterodimer for Vaccine Development

B. Pierce, T. Fuerst, E. Toth, 2021, Viruses.

Interaction of apurinic/apyrimidinic endonuclease 2 (Apn2) with Myh1 DNA glycosylase in fission yeast.

A. Lu, E. Toth, Bor-Jang Hwang, 2014, DNA repair.

Structure-based design of N-substituted 1-hydroxy-4-sulfamoyl-2-naphthoates as selective inhibitors of the Mcl-1 oncoprotein.

Alexander D. MacKerell, P. Wilder, J. Yap, 2016, European journal of medicinal chemistry.

Alternatively Expressed Domains of AU-rich Element RNA-binding Protein 1 (AUF1) Regulate RNA-binding Affinity, RNA-induced Protein Oligomerization, and the Local Conformation of Bound RNA Ligands*

G. M. Wilson, Jeff D Ballin, E. Toth, 2010, The Journal of Biological Chemistry.

Covalent Small Molecule Inhibitors of Ca2+-Bound S100B

Timothy L. Foley, David J Weber, A. Jadhav, 2014, Biochemistry.

Metal-Assisted and Microwave-Accelerated Evaporative Crystallization: Proof-of-Principle Application to Proteins

K. Aslan, E. Toth, D. Seifu, 2015 .

Design of a native-like secreted form of the hepatitis C virus E1E2 heterodimer

Johnathan D. Guest, B. Pierce, T. Cleveland, 2021, Proceedings of the National Academy of Sciences.

Contributions of the histidine side chain and the N-terminal alpha-amino group to the binding thermodynamics of oligopeptides to nucleic acids as a function of pH.

G. M. Wilson, Jeff D Ballin, M. Record, 2010, Biochemistry.

Small Molecule Inhibitors of Ca(2+)-S100B Reveal Two Protein Conformations.

Alexander D. MacKerell, M. I. Ansari, David J Weber, 2016, Journal of medicinal chemistry.

Hydroxylated Dimeric Naphthoquinones Increase the Generation of Reactive Oxygen Species, Induce Apoptosis of Acute Myeloid Leukemia Cells and Are Not Substrates of the Multidrug Resistance Proteins ABCB1 and ABCG2

E. Sausville, A. Jaiswal, F. Rassool, 2016, Pharmaceuticals.

Structure-Based Discovery of a Novel Pentamidine-Related Inhibitor of the Calcium-Binding Protein S100B.

Alexander D. MacKerell, David J Weber, R. Godoy-Ruiz, 2012, ACS medicinal chemistry letters.

Small molecules bound to unique sites in the target protein binding cleft of calcium-bound S100B as characterized by nuclear magnetic resonance and X-ray crystallography.

Alexander D. MacKerell, David J Weber, P. Wilder, 2009, Biochemistry.

Divalent metal ion complexes of S100B in the absence and presence of pentamidine.

Alexander D. MacKerell, David J Weber, P. Wilder, 2008, Journal of molecular biology.

A direct interaction between NQO1 and a chemotherapeutic dimeric naphthoquinone

Edward A. Sausville, Edwin Pozharski, E. Sausville, 2016, BMC Structural Biology.

Mapping microscopic order in plant and mammalian cells and tissues: novel differential polarization attachment for new generation confocal microscopes (DP-LSM)

I. Pomozi, G. Garab, G. Steinbach, 2014, Methods and applications in fluorescence.

Skin Vaccination with Ebola Virus Glycoprotein Using a Polyphosphazene-Based Microneedle Patch Protects Mice against Lethal Challenge

M. Prausnitz, G. Ofek, T. Fuerst, 2022, Journal of functional biomaterials.

Crystal structure of a DinB family error-prone DNA polymerase from Sulfolobus solfataricus

L. Silvian, T. Ellenberger, M. Goodman, 2001, Nature Structural Biology.

Structural and functional analysis of the pro-domain of human cathelicidin, LL-37.

M. Pazgier, Weirong Yuan, Wuyuan Lu, 2013, Biochemistry.

Crystal structure of human methyl-binding domain IV glycosylase bound to abasic DNA.

E. Toth, Matthew C. Begley, A. Maiti, 2012, Journal of molecular biology.

Yeast nuclear RNA processing.

E. Toth, J. Bernstein, 2012, World journal of biological chemistry.

Engineering subtilisin proteases that specifically degrade active RAS

Eun Jung Choi, David J Weber, Yanan He, 2021, Communications Biology.

Engineering subtilisin proteases that specifically degrade active RAS

Eun Jung Choi, David J Weber, Yanan He, 2021, Communications biology.

Engineering protein-specific proteases: targeting active RAS

Eun Jung Choi, David J Weber, Yanan He, 2020, bioRxiv.

Target binding to S100B reduces dynamic properties and increases Ca(2+)-binding affinity for wild type and EF-hand mutant proteins.

David J Weber, M. Liriano, R. Ishima, 2012, Journal of molecular biology.

A structural hinge in eukaryotic MutY homologues mediates catalytic activity and Rad9-Rad1-Hus1 checkpoint complex interactions.

A. Lu, D. Chang, G. Shi, 2010, Journal of molecular biology.

A unique IBMPFD-related P97/VCP mutation with differential binding pattern and subcellular localization.

D. Gozuacik, E. Toth, Y. Erzurumlu, 2013, The international journal of biochemistry & cell biology.

Structure of human apurinic/apyrimidinic endonuclease 1 with the essential Mg2+ cofactor

E. Pozharski, E. Toth, A. Drohat, 2013, Acta crystallographica. Section D, Biological crystallography.

Specific Protein Domains Mediate Cooperative Assembly of HuR Oligomers on AU-rich mRNA-destabilizing Sequences*

G. M. Wilson, Jeff D Ballin, E. Toth, 2007, Journal of Biological Chemistry.

The crystal structure of human quinolinic acid phosphoribosyltransferase in complex with its inhibitor phthalic acid

Eric A. Toth, E. Toth, Shuja S. Malik, 2013, Proteins.

Hsp70 Is a Novel Posttranscriptional Regulator of Gene Expression That Binds and Stabilizes Selected mRNAs Containing AU-Rich Elements

G. M. Wilson, G. Brewer, E. Toth, 2012, Molecular and Cellular Biology.

Transamidase site-targeted agents alter the conformation of the transglutaminase cancer stem cell survival protein to reduce GTP binding activity and cancer stem cell survival

David J Weber, J. Lakowicz, C. Kerr, 2016, Oncogene.

Characterization of the Essential Activities of Saccharomyces cerevisiae Mtr4p, a 3′→5′ Helicase Partner of the Nuclear Exosome*

G. M. Wilson, E. Toth, Dimeka N. Patterson, 2008, Journal of Biological Chemistry.

Unique properties of the Mtr4p-poly(A) complex suggest a role in substrate targeting.

G. M. Wilson, Jeff D Ballin, E. Toth, 2010, Biochemistry.

Coordination of MYH DNA glycosylase and APE1 endonuclease activities via physical interactions.

Weirong Yuan, Wuyuan Lu, A. Lu, 2013, DNA repair.

The structure of adenylosuccinate lyase, an enzyme with dual activity in the de novo purine biosynthetic pathway.

T. Yeates, E. Toth, 2000, Structure.

The crystal structure of the bifunctional primase-helicase of bacteriophage T7.

M. Sawaya, Yifan Cheng, T. Ellenberger, 2003, Molecular cell.

Crystal Structure of DinB from Sulfolobus solfataricus

L. Silvian, T. Ellenberger, M. Goodman, 2001 .

Induction of broadly neutralizing antibodies using a secreted form of the hepatitis C virus E1E2 heterodimer as a vaccine candidate

Johnathan D. Guest, B. Pierce, T. Fuerst, 2022, Proceedings of the National Academy of Sciences of the United States of America.

The crystal structure of adenylosuccinate lyase from Pyrobaculum aerophilum reveals an intracellular protein with three disulfide bonds.

T. Yeates, S. Marqusee, C. Worby, 2000, Journal of molecular biology.

Evaluation of phase accuracy via topological and geometrical analysis of electron-density maps.

C Colovos, E A Toth, T O Yeates, 2000, Acta crystallographica. Section D, Biological crystallography.

Crystal structures of human 3-hydroxyanthranilate 3,4-dioxygenase with native and non-native metals bound in the active site.

E. Pozharski, S. Michel, E. Toth, 2017, Acta crystallographica. Section D, Structural biology.

Glycosylation shapes the efficacy and safety of diverse protein, gene and cell therapies.

James T. Sorrentino, N. Lewis, T. Fuerst, 2023, Biotechnology advances.

Structure-Based Design of Hepatitis C Virus E2 Glycoprotein Improves Serum Binding and Cross-Neutralization

Johnathan D. Guest, B. Pierce, J. Ball, 2020, Journal of Virology.

Structure-based design of hepatitis C virus E2 glycoprotein

Johnathan D. Guest, B. Pierce, J. Ball, 2020 .

The effects of CapZ peptide (TRTK-12) binding to S100B-Ca2+ as examined by NMR and X-ray crystallography.

Laura E. Thompson, David J Weber, P. Wilder, 2010, Journal of molecular biology.

Prospects for developing an Hepatitis C virus E1E2‐based nanoparticle vaccine

T. Fuerst, A. Andrianov, E. Toth, 2023, Reviews in medical virology.

In vitro screening and structural characterization of inhibitors of the S100B-p53 interaction.

David J Weber, A. MacKerell, P. Wilder, 2010, International journal of high throughput screening.

Small molecules bound to unique sites in the target protein binding cleft of calcium-bound S100B as characterized by nuclear magnetic resonance and X-ray crystallography.

Alexander D. MacKerell, David J Weber, P. Wilder, 2009, Biochemistry.

Biological Crystallography Structure of Human Apurinic/apyrimidinic Endonuclease 1 with the Essential Mg 2+ Cofactor

E. Pozharski, E. Toth, A. Drohat, 2022 .

Crystal structure of human methyl-binding domain IV glycosylase bound to abasic DNA.

E. Toth, Matthew C. Begley, A. Maiti, 2012, Journal of molecular biology.