T. Zakar

发表

The in vivo control of prostaglandin H synthase-2 messenger ribonucleic acid expression in the human amnion at parturition.

W. Walters, Renée F. Johnson, W. Giles, 2002, The Journal of clinical endocrinology and metabolism.

Estrogen receptor (ER) expression and function in the pregnant human myometrium: estradiol via ERα activates ERK1/2 signaling in term myometrium.

H. Tan, S. Mesiano, T. Zakar, 2012, The Journal of endocrinology.

Prostaglandin endoperoxide H synthase mRNA expression in the human amnion and decidua during pregnancy and in the amnion at preterm labour.

T. Zakar, D. Olson, J. Angelova, 1999, Molecular human reproduction.

Maternal asthma is associated with reduced female fetal growth.

P. Gibson, Roger Smith, V. Clifton, 2003, American journal of respiratory and critical care medicine.

Fetal sex affects expression of renin-angiotensin system components in term human decidua.

B. Morris, F. Marques, E. Lumbers, 2012, Endocrinology.

Regulation of the renin-angiotensin system (RAS) in BeWo and HTR-8/SVneo trophoblast cell lines.

E. Lumbers, T. Zakar, K. Pringle, 2012, Placenta.

Nitric oxide in platelets.

M. Radomski, T. Zakar, E. Salas, 1996, Methods in enzymology.

[9] Nitric oxide in platelets

M. Radomski, T. Zakar, E. Salas, 1996 .

Pathological interactions with the timing of birth and uterine activation

H. Parkington, E. Chan, Roger Smith, 2007, The Australian & New Zealand journal of obstetrics & gynaecology.

Methylation of Promoter Regions of Genes of the Human Intrauterine Renin Angiotensin System and Their Expression

E. Lumbers, C. Mitchell, T. Zakar, 2015, International journal of endocrinology.

Glucocorticoid stimulation of amnion cell prostaglandin synthesis: suppression by protein kinase C inhibitors and independence of phorbol ester-sensitive protein kinase C.

T. Zakar, D. Olson, E. MacLeod, 1992, Biochimica et biophysica acta.

Prostaglandin endoperoxide H synthase-1 and -2 mRNA levels and enzyme activity in human decidua at term labor.

T. Zakar, D. Olson, J. Hirst, 1998 .

Prostaglandin endoperoxide-H synthase-1 and -2 messenger ribonucleic acid levels in human amnion with spontaneous labor onset.

T. Zakar, D. Olson, J. Hirst, 1995, The Journal of clinical endocrinology and metabolism.

Glucocorticoids stimulate the expression of prostaglandin endoperoxide H synthase-2 in amnion cells.

T. Zakar, D. Olson, J. Hirst, 1995, Endocrinology.

Mammalian labor: variations on a theme by amniota.

Roger Smith, T. Zakar, G. Madsen, 2013, Endocrinology.

Regulation of prostaglandin synthesis in the human uterus.

T. Zakar, F. Hertelendy, 2001 .

Regulation of prostaglandin synthesis in the human uterus

T. Zakar, F. Hertelendy, 2001, The Journal of maternal-fetal medicine.

Tyrphostins inhibit lipopolysaccharide induced preterm labor in mice

D. Zaragoza, T. Zakar, D. Olson, 2002, Journal of perinatal medicine.

Prostaglandin endoperoxide H synthase (PGHS) activity and PGHS-1 and -2 messenger ribonucleic acid abundance in human chorion throughout gestation and with preterm labor.

T. Zakar, D. Olson, J. Mijovic, 1998, The Journal of clinical endocrinology and metabolism.

Prostaglandin Endoperoxide H Synthase-1 and -2 mRNA Levels and Enzyme Activity in Human Decidua at Term Labor

T. Zakar, J. Hirst, J. Mijovic, 1998, The Journal of the Society for Gynecologic Investigation: JSGI.

Regulation of prostaglandin H2 synthase-2 expression in primary human amnion cells by tyrosine kinase dependent mechanisms.

D. Bhardwaj, K. Eyster, T. Zakar, 1998, Biochimica et biophysica acta.

Current Concepts in Prostaglandin Regulation for Birth

T. Zakar, D. Olson, J. Mijovic, 1999 .

The Control of Prostaglandin Endoperoxide H-Synthase-2 Expression in the Human Chorion Laeve at Term

W. Walters, Renée F. Johnson, W. Giles, 2003, The Journal of the Society for Gynecologic Investigation: JSGI.

The in vivo control of prostaglandin H synthase-2 messenger ribonucleic acid expression in the human amnion at parturition.

W. Walters, Renée F. Johnson, W. Giles, 2002, The Journal of clinical endocrinology and metabolism.

Prostaglandin endoperoxide-H synthase (PGHS) activity and immunoreactive PGHS-1 and PGHS-2 levels in human amnion throughout gestation, at term, and during labor.

B. Resch, T. Zakar, D. Olson, 1994, The Journal of clinical endocrinology and metabolism.

Expression of glucocorticoid receptor messenger ribonucleic acid transcripts in the human placenta at term.

Renée F. Johnson, Roger Smith, V. Clifton, 2008, The Journal of clinical endocrinology and metabolism.

Relative binding affinities of testosterone, 19-nortestosterone and their 5α-reduced derivatives to the androgen receptor and to other androgen-binding proteins: a suggested role of 5α-reductive steroid metabolism in the dissociation of “myotropic” and “androgenic” activities of 19-nortestosterone

M. Tóth, T. Zakar, 1982 .

Steroid-binding properties of the rat seminal vesicle androgen receptor: short-term and long-term competition of various steroids with radioactive dihydrotestosterone.

M. Toth, T. Zakar, 1982, Journal of steroid biochemistry.

Studies on the androgen receptor of the rat seminal vesicle: comparison of the binding characteristics of dihydrotestosterone and testosterone.

M. Toth, T. Zakar, 1980, Journal of steroid biochemistry.

Characterization of the cytoplasmic androgen receptor of rat seminal vesicle

M. Tóth, T. Zakar, 1977, Steroids.

Different binding of testosterone, 19-nortestosterone and their 5 alpha-reduced derivatives to the androgen receptor of the rat seminal vesicle: a step toward the understanding of the anabolic action of nortesterone.

M. Toth, T. Zakar, 1982, Endokrinologie.

A Pathway for the Regulation of Prostaglandins and Parturition

S. Brown, T. Zakar, D. Olson, 1992 .

Control of Prostaglandin Production in Human Amnion

T. Zakar, D. Olson, F. Potestio, 1990 .

Mechanisms regulating prostaglandin H2 synthase-2 mRNA level in the amnion and chorion during pregnancy.

Renée F. Johnson, W. Giles, A. Bisits, 2006, The Journal of endocrinology.

Prostaglandins and the myometrium and cervix.

T. Zakar, F. Hertelendy, 2004, Prostaglandins, leukotrienes, and essential fatty acids.

Glucocorticoids stimulate prostaglandin synthesis in human amnion cells by a receptor-mediated mechanism.

T. Zakar, D. Olson, F. Potestio, 1988, The Journal of clinical endocrinology and metabolism.

Chapter 9 The Endocrinology of late pregnancy and parturition

B. Mitchell, T. Zakar, 1998 .

Intracrine Control of Estrogen Action in Human Gestational Tissues at Parturition

K. Kwek, Roger Smith, G. Yeo, 2004, The Journal of the Society for Gynecologic Investigation: JSGI.

Regulation of prostaglandin endoperoxide H synthase by glucocorticoids and activators of protein kinase C in the human amnion.

T. Zakar, D. Olson, J. Hirst, 1994, Journal of reproduction and fertility.

Prostaglandin endoperoxide H synthase (PGHS)-1 and -2 expression and activity in human chorion and decidua

T. Zakar, D. Olson, J. Mijovic, 1998 .

Stimulation of human amnion prostaglandin E2 production by activators of protein kinase-C.

T. Zakar, D. Olson, 1988, The Journal of clinical endocrinology and metabolism.

Progesterone Receptor Isoform Expression in the Guinea Pig Myometrium From Normal and Growth Restricted Pregnancies

I. Symonds, T. Zakar, J. Hirst, 2010, Reproductive Sciences.

Relative binding affinities of testosterone, 19-nortestosterone and their 5 alpha-reduced derivatives to the androgen receptor and to other androgen-binding proteins: a suggested role of 5 alpha-reductive steroid metabolism in the dissociation of "myotropic" and "androgenic" activities of 19-nortest

M. Toth, T. Zakar, 1982, Journal of steroid biochemistry.

Progesterone Receptor Expression Declines in the Guinea Pig Uterus during Functional Progesterone Withdrawal and in Response to Prostaglandins

T. Zakar, Toni N Welsh, J. Hirst, 2014, PloS one.

Histone Deacetylase Inhibitors: Providing New Insights and Therapeutic Avenues for Unlocking Human Birth

W. M. Hussein, J. Paul, T. Zakar, 2021, Reproductive Sciences.

Birth and Neonatal Transition in the Guinea Pig: Experimental Approaches to Prevent Preterm Birth and Protect the Premature Fetus

D. Walker, T. Zakar, J. Hirst, 2018, Front. Physiol..

Perinatal compromise contributes to programming of GABAergic and glutamatergic systems leading to long‐term effects on offspring behaviour

T. Zakar, J. Hirst, H. Palliser, 2019, Journal of neuroendocrinology.

Progesterone production in granulosa cells of the domestic fowl: effects of incubation media, pH, cell density and some other factors

T. Zakar, F. Hertelendy, E. Asem, 1984 .

The expression of genes involved in myometrial contractility changes during ex situ culture of pregnant human uterine smooth muscle tissue

J. Paul, T. Zakar, M. Ilicic, 2017, Journal of smooth muscle research = Nihon Heikatsukin Gakkai kikanshi.

Separation of Bioactive Prostaglandins and their Metabolites by Reversed-Phase Thin-Layer Chromatography

P. Zarzycki, S. Mesiano, T. Zakar, 2003, JPC – Journal of Planar Chromatography – Modern TLC.

Prostaglandin endoperoxide synthase kinetics in human amnion before and after labor at term and following preterm labor.

T. Zakar, D. Olson, J. Walton, 1993, Placenta.

Promoter Methylation Pattern Controls Corticotropin Releasing Hormone Gene Activity in Human Trophoblasts

R. Scott, T. Zakar, M. Bowman, 2017, PloS one.

Tyrosine kinase inhibitors block the glucocorticoid stimulation of prostaglandin endoperoxide H synthase expression in amnion cells.

D. Bhardwaj, T. Zakar, D. Olson, 1999, Canadian journal of physiology and pharmacology.

Effects of mammalian LH, cyclic AMP and phosphodiesterase inhibitors on steroidogenesis, lactate production, glucose uptake and utilization by avian granulosa cells.

T. Zakar, F. Hertelendy, 1980, Biology of reproduction.

Regulation of myometrial smooth muscle functions.

T. Zakar, F. Hertelendy, 2004, Current pharmaceutical design.

Genes upregulated in the amnion at labour are bivalently marked by activating and repressive histone modifications

M. Mitchell, C. Mitchell, T. Zakar, 2019, Molecular human reproduction.

7 DNA Methylation in Development

T. Zakar, Xin Pan, Roger Smith, 2017 .

DNA methylation in development

T. Zakar, Xin Pan, Roger Smith, 2012 .

Methylation of the Corticotropin Releasing Hormone Gene Promoter in BeWo Cells: Relationship to Gene Activity

R. Scott, T. Zakar, M. Bowman, 2015, International journal of endocrinology.

Increased progesterone receptor A expression in labouring human myometrium is associated with decreased promoter occupancy by the histone demethylase JARID1A.

K. Maiti, C. Mitchell, T. Zakar, 2014, Molecular human reproduction.

Term myometrium is characterized by increased activating epigenetic modifications at the progesterone receptor-A promoter.

C. Mitchell, T. Zakar, G. Madsen, 2012, Molecular human reproduction.

Nuclear Progesterone Receptor Expression in the Human Fetal Membranes and Decidua at Term Before and After Labor

B. Mercer, S. Mesiano, T. Zakar, 2009, Reproductive Sciences.

Modulation of Progesterone Receptor Isoform Expression in Pregnant Human Myometrium

J. Paul, T. Zakar, M. Ilicic, 2017, BioMed research international.

The Regulation of Uterine Function During Parturition: an Update and Recent Advances

J. Paul, T. Zakar, M. Ilicic, 2020, Reproductive Sciences.

Effects of Fetal Sex on Expression of the (Pro)renin Receptor and Genes Influenced by its Interaction With Prorenin in Human Amnion

E. Lumbers, C. Mitchell, T. Zakar, 2015, Reproductive Sciences.

Prostaglandins differentially modulate progesterone receptor-A and -B expression in human myometrial cells: evidence for prostaglandin-induced functional progesterone withdrawal.

S. Mesiano, T. Zakar, B. Sanborn, 2004, The Journal of clinical endocrinology and metabolism.

The action of epidermal growth factor on human amnion prostaglandin E2 output.

T. Zakar, D. Olson, 1988, Canadian journal of physiology and pharmacology.

Steroidogenesis in avian granulosa cells: early and late kinetics of oLH- and dibutyryl cyclic AMP-promoted progesterone production.

T. Zakar, F. Hertelendy, 1980, Biology of reproduction.

Prostaglandin H2 synthase‐1 and ‐2 expression in guinea pig gestational tissues during late pregnancy and parturition

W. Walters, S. Mesiano, C. Mitchell, 2005, The Journal of physiology.

Stimulation of cultured amnion cell prostaglandin endoperoxide H synthase activity by glucocorticoids and phorbol ester.

T. Zakar, D. Olson, Z. Smieja, 1993, American journal of obstetrics and gynecology.

Regulation of prostaglandin synthesis in the human amnion.

T. Zakar, D. Olson, K. Milne, 1991, Reproduction, fertility, and development.

Prostaglandin-endoperoxide H synthase-2 expression and activity increases with term labor in human chorion.

T. Zakar, D. Olson, J. Mijovic, 1997, The American journal of physiology.

Regulation of prostaglandin endoperoxide H2 synthase in term human gestational tissues.

T. Zakar, D. Olson, J. Hirst, 1996, Acta physiologica Hungarica.

Mechanisms Leading to Increased Risk of Preterm Birth in Growth-Restricted Guinea Pig Pregnancies

T. Zakar, Toni N Welsh, M. Kelleher, 2014, Reproductive Sciences.

PTGS2 (prostaglandin endoperoxide synthase-2) expression in term human amnion in vivo involves rapid mRNA turnover, polymerase-II 5'-pausing, and glucocorticoid transrepression.

Renée F. Johnson, A. Bisits, C. Mitchell, 2011, Endocrinology.

Fetal Membrane Epigenetics

J. Paul, T. Zakar, 2020, Frontiers in Physiology.

Inflammatory and steroid receptor gene methylation in the human amnion and decidua.

E. Lumbers, C. Mitchell, T. Zakar, 2013, Journal of molecular endocrinology.

Epigenetic regulation of progesterone receptors and the onset of labour.

J. Paul, T. Zakar, M. Ilicic, 2019, Reproduction, fertility, and development.

Inhibitory effect of prostaglandin E2 on the incorporation of 3H-thymidine into the DNA of thymus cells.

M. Toth, T. Zakar, F. Antoni, 1975, Acta biochimica et biophysica; Academiae Scientiarum Hungaricae.

Intrauterine Tissue Prostaglandin Synthesis: Regulatory Mechanisms

T. Zakar, D. Olson, 1993 .

Regulation of inflammatory genes in decidual cells: Involvement of the bromodomain and extra-terminal family proteins

T. Zakar, Mary H Norris, J. Hirst, 2023, PloS one.

Regulation of 15-hydroxyprostaglandin dehydrogenase (PGDH) gene activity, messenger ribonucleic acid processing, and protein abundance in the human chorion in late gestation and labor.

Renée F. Johnson, V. Clifton, C. Mitchell, 2004, The Journal of clinical endocrinology and metabolism.

Molecular characterization of renin-angiotensin system components in human intrauterine tissues and fetal membranes from vaginal delivery and cesarean section.

B. Morris, F. Marques, E. Lumbers, 2010, Placenta.

147. MOLECULAR CHARACTERIZATION OF RENIN–ANGIOTENSIN SYSTEM COMPONENTS IN HUMAN INTRAUTERINE TISSUES AND FETAL MEMBRANES FROM VAGINAL DELIVERY AND CAESAREAN SECTION

B. Morris, F. Marques, E. Lumbers, 2010 .

Preterm Labor is a Distinct Process from Term Labor following Computational Analysis of Human Myometrium.

C. Pennell, Carol A. Wang, J. Paul, 2021, American journal of obstetrics and gynecology.

PGHS-1 and -2 expression and activity during gestation and at term in human chorion and decidua

T. Zakar, D. Olson, J. Hirst, 1996 .

Progesterone withdrawal: key to parturition.

T. Zakar, Tamas Zakar, Frank Hertelendy, 2007, American journal of obstetrics and gynecology.

Reduced 11beta-hydroxysteroid dehydrogenase type 2 activity is associated with decreased birth weight centile in pregnancies complicated by asthma.

P. Gibson, V. Clifton, V. Murphy, 2002, The Journal of clinical endocrinology and metabolism.

Prostaglandin H synthase-2 gene regulation in the amnion at labour: histone acetylation and nuclear factor kappa B binding to the promoter in vivo.

W. Giles, C. Mitchell, T. Zakar, 2008, Molecular human reproduction.

How does progesterone relax the uterus in pregnancy?

S. Mesiano, T. Zakar, 2011, The New England journal of medicine.

Assignment of anabolic-androgenic and antiandrogenic properties to some chlorine-substituted steroids on the basis of their binding characteristics to the androgen receptor of the rat seminal vesicle.

M. Toth, T. Zakar, G. Kaufmann, 2009, Experimental and clinical endocrinology.

The intrauterine renin–angiotensin system: Sex‐specific effects on the prevalence of spontaneous preterm birth

E. Lumbers, T. Zakar, K. Pringle, 2017, Clinical and experimental pharmacology & physiology.

Molecular evidence of a (pro)renin/ (pro)renin receptor system in human intrauterine tissues in pregnancy and its association with PGHS-2

E. Lumbers, C. Mitchell, T. Zakar, 2011, Journal of the renin-angiotensin-aldosterone system : JRAAS.

15-Hydroxyprostaglandin Dehydrogenase Expression and Localization in Guinea Pig Gestational Tissues During Late Pregnancy and Parturition

J. Paul, S. Mesiano, T. Zakar, 2012, Reproductive Sciences.

Studies on glucocorticoid hormone actions in the regulation of human amnion PGHS.

T. Zakar, D. Olson, 1995, Reproduction, fertility, and development.

The Endocrinology of Late Pregnancy and Parturition

B. Mitchell, T. Zakar, 1996 .

Regulation of 20α-Hydroxysteroid Dehydrogenase Expression in Term Pregnant Human Myometrium Ex Vivo.

W. M. Hussein, J. Paul, T. Zakar, 2023, Reproductive sciences.

20α-Hydroxysteroid Dehydrogenase Expression in the Human Myometrium at Term and Preterm Birth: Relationships to Fetal Sex and Maternal Body Mass Index

J. Paul, T. Zakar, J. Phung, 2023, Reproductive Sciences.

Protein kinase-C stimulatory activity in human amnion cytosol.

K. Eyster, T. Zakar, D. Olson, 1993, The Journal of clinical endocrinology and metabolism.

The regulation of human parturition

E. Chan, V. Clifton, S. Mesiano, 2005 .

Classification of anabolic steroids using the method of competitive metabolism.

M. Toth, T. Zakar, 2009, Experimental and clinical endocrinology.

Prostaglandin H synthase-2 expression increases in human gestational tissues with spontaneous labour onset.

T. Zakar, D. Olson, J. Hirst, 1995, Reproduction, fertility, and development.