K. Appell

发表

2 - Combinatorial Chemistry and High-Throughput Screening in Drug Discovery and Development

John J. Baldwin, W. Egan, J. Baldwin, 2001 .

Characterization of the reversible conformational equilibrium of the cytoplasmic domain of erythrocyte membrane band 3.

P. Low, K. Appell, M. A. Westfall, 1984, The Journal of biological chemistry.

Sulfonamido-aryl ethers as bradykinin B1 receptor antagonists.

S. Bevan, H. Gstach, Viral Patel, 2009, Bioorganic & medicinal chemistry letters.

Synthesis of (3,4-dimethoxyphenoxy)alkylamino acetamides as orexin-2 receptor antagonists.

M. Webb, I. Henderson, J. Saunders, 2008, Bioorganic & medicinal chemistry letters.

A Novel High-Throughput Screening Format to Identify Inhibitors of Secreted Acid Sphingomyelinase

I. Tabas, M. Polokoff, R. Mintzer, 2005, Journal of biomolecular screening.

Biological Characterization of Neurokinin Antagonists Discovered Through Screening of a Combinatorial Library

T. Chung, D. Chelsky, K. Solly, 1998 .

Chemokine receptor-ligand interactions measured using time-resolved fluorescence.

James Inglese, S. Patel, J. Burbaum, 1998, Biochemistry.

WIN 64821, a novel neurokinin antagonist produced by an Aspergillus sp. II. Biological activity.

C. Barrow, A. Gillum, J. Oleynek, 1994, The Journal of antibiotics.

Identification and characterization of small‐molecule inhibitors of Tie2 kinase

M. Webb, R. Wen, I. Henderson, 2008, FEBS letters.

Antagonists that demonstrate species differences in neurokinin-1 receptors.

B. Tomczuk, K. Appell, B. J. Fragale, 1992, Molecular pharmacology.

Preparation and characterization of monoclonal antibodies to substance P.

J. Yanni, K. Appell, P. Frickey, 1991, Hybridoma.

Cell Cycle Progression following Naive T Cell Activation Is Independent of Jak3/Common -Chain Cytokine Signals

K. Appell, Tsung H. Lin, Min-Min Shi, 2009 .

-Chain Cytokine Signals g Activation Is Independent of Jak3/Common Cell Cycle Progression following Naive T Cell

L. Berg, K. Appell, Tsung H. Lin, 2009 .

AHR‐16303B, a Novel Antagonist of 5‐HT2 Receptors and Voltage‐Sensitive Calcium Channels

D. A. Walsh, K. Appell, R. J. Barrett, 1991, Journal of cardiovascular pharmacology.

Janus-kinase-3-dependent signals induce chromatin remodeling at the Ifng locus during T helper 1 cell differentiation.

L. Berg, K. Appell, Tsung H. Lin, 2008, Immunity.

Novel pyrrolidine heterocycles as CCR1 antagonists.

M. Webb, M. Ohlmeyer, Camelia Chiriac, 2010, Bioorganic & medicinal chemistry letters.

Synthesis and substance P antagonist activity of naphthimidazolium derivatives.

M. Logan, B. Tomczuk, J. Yanni, 1992, Journal of medicinal chemistry.

Synthesis and substance P receptor binding activity of androstano[3,2-b]pyrimido[1,2-a]benzimidazoles.

M. Logan, K. Appell, L. Aimone, 1992, Journal of medicinal chemistry.

Imidazo[4,5-b]quinoxaline cyanines as neurokinin antagonists.

M. Logan, B. Tomczuk, J. Yanni, 1991, Journal of medicinal chemistry.

Identification and initial evaluation of 4-N-aryl-[1,4]diazepane ureas as potent CXCR3 antagonists.

Maria L Webb, Michael Snider, Zahid Hussain, 2006, Bioorganic & medicinal chemistry letters.

Neurotransmitter release from bradykinin-stimulated PC12 cells. Stimulation of cytosolic calcium and neurotransmitter release.

K. Appell, D. Barefoot, 1989, Biochemical Journal.

Selective functional inhibition of JAK-3 is sufficient for efficacy in collagen-induced arthritis in mice.

Xin Xu, Mary Collins, Maria L Webb, 2010, Arthritis and rheumatism.

Kinase inhibitors as drugs for chronic inflammatory and immunological diseases: progress and challenges

Maria L Webb, M. Webb, C. Carroll, 2008 .

Identification of immunoreactive forms of human erythrocyte band 3 in nonerythroid cells.

P. Low, U. Schauer, D. Drenckhahn, 1984, European journal of cell biology.

Cell Cycle Progression following Naive T Cell Activation Is Independent of Jak3/Common γ-Chain Cytokine Signals1

L. Berg, K. Appell, Leslie J. Berg, 2009, The Journal of Immunology.

Characterization of the stimulatory action of insulin on insulin-like growth factor II binding to rat adipose cells. Differences in the mechanism of insulin action on insulin-like growth factor II receptors and glucose transporters.

I. Simpson, S. Cushman, K. Appell, 1988, The Journal of biological chemistry.

Insulin-induced subcellular redistribution of insulin-like growth factor II receptors in the rat adipose cell. Counterregulatory effects of isoproterenol, adenosine, and cAMP analogues.

I. Simpson, S. Cushman, P. Lönnroth, 1988, The Journal of biological chemistry.

Ultra-High Throughput Screen of Two-Million-Member Combinatorial Compound Collection in a Miniaturized, 1536-Well Assay Format

M Webb, D Dunn, M Orlowski, 2000, Journal of biomolecular screening.

Partial structural characterization of the cytoplasmic domain of the erythrocyte membrane protein, band 3.

P. Low, K C Appell, P S Low, 1981, The Journal of biological chemistry.

Evaluation of structural interdependence of membrane-spanning and cytoplasmic domains of band 3.

P. Low, K. Appell, K. C. Appell, 1982 .

Novel pyrrolidine ureas as C-C chemokine receptor 1 (CCR1) antagonists.

Ruiyan Liu, Maria L Webb, M. Webb, 2009, Journal of medicinal chemistry.

2-Benzimidazolyl-9-(chroman-4-yl)-purinone derivatives as JAK3 inhibitors.

David J Diller, Maria L Webb, M. Webb, 2009, Bioorganic & medicinal chemistry letters.

Anthrotainin, an inhibitor of substance P binding produced by Gliocladium catenulatum.

S. Wong, A. Gillum, K. Appell, 1993, The Journal of antibiotics.

Synthesis and initial evaluation of novel, non-peptidic antagonists of the alpha(v)-integrins alpha(v)beta(3) and alpha(v)beta(5).

M. Webb, M. Ohlmeyer, Hong Li, 2009, Bioorganic & medicinal chemistry letters.

Kinase inhibitors as drugs for chronic inflammatory and immunological diseases: progress and challenges.

M. Webb, C. Carroll, K. Appell, 2008, Expert opinion on therapeutic targets.

A pharmacological and biochemical examination of AHR‐16462B, a novel calcium antagonist coronary vasodilator/antihypertensive

K. Appell, R. J. Barrett, A. Proakis, 1991 .

Differential scanning calorimetry of milk fat globule membranes.

P. Low, T. W. Keenan, K. Appell, 1982, Biochimica et biophysica acta.

Identification of CXCR3 receptor agonists in combinatorial small-molecule libraries.

Maria L Webb, M. Webb, I. Henderson, 2006, Biochemical and biophysical research communications.