M. Sakarellos-Daitsiotis

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Linear epitopes of two different autoantigens-La/SSB and myelin basic protein--with a high degree of molecular similarity, cause different humoral immune responses.

A. Tzioufas, H. Moutsopoulos, A. Terzoglou, 2003 .

Synthesis and biological activity of lipophilic analogs of the cationic antimicrobial active peptide anoplin

A. Koukkou, M. Sakarellos-Daitsiotis, Kostas Chionis, 2016, Journal of peptide science : an official publication of the European Peptide Society.

Design and synthesis of cationic Aib‐containing antimicrobial peptides: conformational and biological studies

C. Drainas, A. Koukkou, C. Sakarellos, 2007, Journal of peptide science : an official publication of the European Peptide Society.

Novel anoplin‐based (lipo)‐peptide models show potent antimicrobial activity

A. Koukkou, M. Sakarellos-Daitsiotis, D. Krikorian, 2021, Journal of peptide science : an official publication of the European Peptide Society.

Aerobic exercise training as a potential source of natural antibodies protective against human immunodeficiency virus‐1

M. Dopsaj, S. Glišić, W. Stringer, 2009, Scandinavian journal of medicine & science in sports.

Protective effect of thiols on wine aroma volatiles.

M. Sakarellos-Daitsiotis, I. Roussis, D. Papadopoulou, 2010 .

Prime boost vaccination approaches with different conjugates of a new HIV-1 gp41 epitope encompassing the membrane proximal external region induce neutralizing antibodies in mice.

U. Dietrich, B. Brill, M. Sakarellos-Daitsiotis, 2012, Vaccine.

Fine specificity of autoantibodies to La/SSB: epitope mapping, and characterization

H. Moutsopoulos, A. Tzioufas, J. Routsias, 1997, Clinical and experimental immunology.

The third-dimensional structure of the complex between an Fv antibody fragment and an analogue of the main immunogenic region of the acetylcholine receptor: a combined two-dimensional NMR, homology, and molecular modeling approach.

J. Kleinjung, A. Mamalaki, S. Tzartos, 2000, Biopolymers.

Zinc ion dependent B-cell epitope, associated with primary Sjogren's syndrome, resides within the putative zinc finger domain of Ro60kD autoantigen: physical and immunologic properties.

A. Tzioufas, H. Moutsopoulos, J. Routsias, 2004, Journal of medicinal chemistry.

Zinc ion dependent B-cell epitope, associated with primary Sjogren's syndrome, resides within the putative zinc finger domain of Ro60kD autoantigen: physical and immunologic properties.

A. Tzioufas, H. Moutsopoulos, J. Routsias, 2004 .

Calreticulin binds preferentially with B cell linear epitopes of Ro60 kD autoantigen, enhancing recognition by anti‐Ro60 kD autoantibodies

G. Panayotou, A. Tzioufas, H. Moutsopoulos, 2003, Clinical and experimental immunology.

HLA‐DQ7 β1 and β2 derived peptides as immunomodulators

M. Zimecki, Z. Szewczuk, C. Sakarellos, 2009, Journal of peptide science : an official publication of the European Peptide Society.

Hydration of the Gly2 and Gly3 peptide oxygens of [Leu5]-enkephalin in aqueous solution as revealed by the combined use of 17O-NMR and Fourier-transform infrared spectroscopy.

I. Gerothanassis, B. Vitoux, C. Sakarellos, 1992, European journal of biochemistry.

Significance of bound residual water in the DMSO solution structure of stable peptide hydrates

V. Tsikaris, C. Sakarellos, M. Sakarellos-Daitsiotis, 1991 .

The Transcriptional ETS2 Repressor Factor Associates with Active and Inactive Erks through Distinct FXF Motifs*

M. Cobb, G. Mavrothalassitis, M. Yazicioglu, 2006, Journal of Biological Chemistry.

Apolipoprotein A‐I peptide models as probes to formulate potential inhibitors of the low‐density lipoprotein oxidation

A. Tselepis, M. Sakarellos-Daitsiotis, C. Tellis, 2011, Journal of peptide science : an official publication of the European Peptide Society.

17O‐nmr studies of the conformational and dynamic properties of enkephalins in aqueous and organic solutions using selectively labeled analogues

I. Gerothanassis, C. Sakarellos, M. Sakarellos-Daitsiotis, 1989, Biopolymers.

Highly constrained cyclic (S,S) ‐CXaaC‐ peptides as inhibitors of fibrinogen binding to platelets

V. Tsikaris, A. Tselepis, C. Sakarellos, 2005, Journal of thrombosis and haemostasis : JTH.

A palmitoylated peptide, derived from the acidic carboxyl-terminal segment of the integrin αIIb cytoplasmic domain, inhibits platelet activation

V. Tsikaris, A. Tselepis, M. Sakarellos-Daitsiotis, 2008, Platelets.

Cationic amphipathic peptide analogs of cathelicidin LL‐37 as a probe in the development of antimicrobial/anticancer agents

M. Lekka, A. Koukkou, M. Sakarellos-Daitsiotis, 2020, Journal of peptide science : an official publication of the European Peptide Society.

Inhibition of platelet activation by peptide analogs of the β3-intracellular domain of platelet integrin αIIbβ3 conjugated to the cell-penetrating peptide Tat(48–60)

J. Goudevenos, P. Stathopoulos, V. Tsikaris, 2009, Platelets.

Study of the anti-idiotypic resonse to anti-LA/SSB autoantibodies using complementary peptides to B- and T-cell epitopes of La/SSB

A. Tzioufas, C. Sakarellos, M. Sakarellos-Daitsiotis, 2001, Arthritis Research.

Influenza virus H5N1 hemagglutinin (HA) T‐cell epitope conjugates: design, synthesis and immunogenicity

O. Planz, K. Droebner, S. Zevgiti, 2011, Journal of peptide science : an official publication of the European Peptide Society.

A palmitoyl-tailed sequential oligopeptide carrier for engineering immunogenic conjugates.

S. Zevgiti, C. Sakarellos, M. Sakarellos-Daitsiotis, 2007, Vaccine.

Arg side-chain-backbone interactions evidenced in model peptides by 17O-NMR spectroscopy.

A. Troganis, V. Moussis, V. Tsikaris, 2000, Biopolymers.

A peptide carrier with a built-in vaccine adjuvant: construction of immunogenic conjugates.

C. Sakarellos, M. Sakarellos-Daitsiotis, D. Krikorian, 2005, Bioconjugate chemistry.

Design, synthesis, and conformational study of biologically active photolabeled analogues of the main immunogenic region of the acetylcholine receptor.

S. Tzartos, V. Tsikaris, V. Theodorou, 2000, Biopolymers.

No evidence of epitope spreading after immunization with the major Sm epitope P-P-G-M-R-P-P anchored to sequential oligopeptide carriers (SOCs).

P. Davaris, L. Nakopoulou, A. Guialis, 2000, Journal of autoimmunity.

Computational screening of branched cyclic peptide motifs as potential enzyme mimetics

Athanassios Stavrakoudis, A. Stavrakoudis, I. Demetropoulos, 2003, Journal of peptide science : an official publication of the European Peptide Society.

Synthesis and thrombolytic properties of some flufenamate derivatives.

M. Verlander, M. Goodman, M. Sakarellos-Daitsiotis, 1978, Thrombosis research.

Changes in the c.d. spectra of calf thymus DNA induced by sequential polypeptides in aqueous solutions. Part I.

V. Tsikaris, C. Sakarellos, M. Sakarellos-Daitsiotis, 1991, International journal of biological macromolecules.

17O‐ and 14N‐nmr studies of Leu‐enkephalin and enkephalin‐related fragments in aqueous solution

I. Gerothanassis, C. Sakarellos, M. Sakarellos-Daitsiotis, 1990, Biopolymers.

Isomerization of the Xaa-Pro peptide bond induced by ionic interactions of arginine.

V. Tsikaris, C. Sakarellos, M. Sakarellos-Daitsiotis, 1996, Biopolymers.

A crystal molecular conformation of leucine‐enkephalin related to the morphine molecule

A Aubry, A. Aubry, N Birlirakis, 1989, Biopolymers.

Anatomy of the antigenic structure of a large memberane autoantigen, the muscle‐type nicotinic acetylcholine receptor

A. Mamalaki, S. Tzartos, V. Tsikaris, 1998, Immunological reviews.

Conformational study of new amphipathic alpha-helical peptide models of apoA-I as potential atheroprotective agents.

N. Coudevylle, C. Alexopoulos, A. Tselepis, 2007, Biopolymers.

Calreticulin synthetic peptide analogues: anti‐peptide antibodies in autoimmune rheumatic diseases

H. Moutsopoulos, A. Tzioufas, C. Sakarellos, 1993, Clinical and experimental immunology.

Sequential oligopeptide carriers, SOCn, as scaffolds for the reconstitution of antigenic proteins: applications in solid phase immunoassays.

C. Alexopoulos, C. Sakarellos, M. Sakarellos-Daitsiotis, 2004, Journal of pharmaceutical and biomedical analysis.

Epitope mapping of the Ro/SSA60KD autoantigen reveals disease‐specific antibody‐binding profiles

A. Tzioufas, C. Sakarellos, M. Sakarellos-Daitsiotis, 1996, European journal of clinical investigation.

Epitope mapping of the 60-kDa Ro/SSA protein: Specific recognition of the main antigenic determinants from the autoimmune rheumatic diseases autoantibodies

H. Moutsopoulos, A. Tzioufas, C. Sakarellos, 1995 .

Mapping the binding domains of the αIIb subunit

L. Michalis, N. Biris, V. Tsikaris, 2003 .

Mapping the binding domains of the alpha(IIb) subunit. A study performed on the activated form of the platelet integrin alpha(IIb)beta(3).

L. Michalis, N. Biris, V. Tsikaris, 2003, European journal of biochemistry.

A study performed on the activated form of the platelet integrin aIIbb3

L. Michalis, N. Biris, V. Tsikaris, 2003 .

T‐cell epitopes of the La/SSB autoantigen: Prediction based on the homology modeling of HLA‐DQ2/DQ7 with the insulin‐B peptide/HLA‐DQ8 complex

Athanassios Stavrakoudis, Aggeliki Kosmopoulou, Metaxia Vlassi, 2006, J. Comput. Chem..

The PPGMRPP repetitive epitope of the Sm autoantigen: Antigenic specificity induced by conformational changes. Application of the Sequential Oligopeptide Carriers (SOCs)

H. Moutsopoulos, P. Vlachoyiannopoulos, C. Alexopoulos, 1997, Letters in Peptide Science.

Immunoreactivity and conformation of the P-P-G-M-R-P-P repetitive epitope of the Sm autoantigen.

H. Moutsopoulos, P. Vlachoyiannopoulos, V. Tsikaris, 2009, International journal of peptide and protein research.

Unmasking the Anti-La/SSB Response in Sera From Patients With Sjogren’s Syndrome by Specific Blocking of Anti-idiotypic Antibodies to La/SSB Antigenic Determinants

A. Tzioufas, H. Moutsopoulos, E. Dotsika, 2002, Molecular medicine.

Physical Activity and Natural Anti-VIP Antibodies: Potential Role in Breast and Prostate Cancer Therapy

M. Dopsaj, N. Veljkovic, S. Glišić, 2011, PloS one.

Sequential polypeptides by matrix‐controlled thermal polymerization. Synthesis and racemization studies

C. Gilon, M. Goodman, C. Sakarellos, 1977 .

B-cell autoepitopes on the acetylcholinesterase-homologous region of human thyroglobulin: association with Graves' disease and thyroid eye disease.

G. Philippou, P. Lymberi, A. Souvatzoglou, 2001, European journal of endocrinology.

Phosphorylated and nonphosphorylated epitopes of the La/SSB autoantigen: comparison of their antigenic and conformational characteristics.

N. Coudevylle, C. Sakarellos, M. Sakarellos-Daitsiotis, 2006, Biopolymers.

B-Cell epitope mapping of DNA topoisomerase I defines epitopes strongly associated with pulmonary fibrosis in systemic sclerosis.

J. Ioannidis, H. Moutsopoulos, P. Vlachoyiannopoulos, 2000, American journal of respiratory cell and molecular biology.

Artificial carriers: a strategy for constructing antigenic/immunogenic conjugates.

C. Sakarellos, M. Sakarellos-Daitsiotis, D. Krikorian, 2006, Current topics in medicinal chemistry.

T cell help is required to induce idiotypic–anti‐idiotypic autoantibody network after immunization with complementary epitope 289–308aa of La/SSB autoantigen in non‐autoimmune mice

E. Dotsika, A. Tzioufas, E. Karagouni, 2004, Clinical and experimental immunology.

Idiotype-anti-idiotype circuit in non-autoimmune mice after immunization with the epitope and complementary epitope 289-308aa of La/SSB: implications for the maintenance and perpetuation of the anti-La/SSB response.

A. Tzioufas, H. Moutsopoulos, E. Dotsika, 2003, Journal of autoimmunity.

Synthesis of a proline-rich [60]fullerene peptide with potential biological activity

C. Toniolo, F. Formaggio, M. Maggini, 2004 .

The clinical relevance of antibodies to ribosomal-P common epitope in two targeted systemic lupus erythematosus populations: a large cohort of consecutive patients and patients with active central nervous system disease

H. Moutsopoulos, A. Tzioufas, K. Boki, 2000, Annals of the rheumatic diseases.

Antigenicity and conformational analysis of the Zn(2+)-binding sites of two Zn(2+)-metalloproteases: Leishmania gp63 and mammalian endopeptidase-24.11.

A. Tzinia, R. Matsas, V. Tsikaris, 1996, The Biochemical journal.

Study of antibody and T cell responses in rabbits immunized with synthetic human B cell epitope analogues of La (SSB) autoantigen

H. Moutsopoulos, A. Tzioufas, M. Manoussakis, 2000, Clinical and experimental immunology.

The value of synthetic linear epitope analogues of La/SSB for the detection of autoantibodies to La/SSB; specificity, sensitivity and comparison of methods

A. Tzioufas, H. Moutsopoulos, V. Tsikaris, 1998, Clinical and experimental immunology.

Compared structures of the free nicotinic acetylcholine receptor main immunogenic region (MIR) decapeptide and the antibody‐bound [A76] MIR analogue: A molecular dynamics simulation from two‐dimensional NMR data

E. Vatzaki, S. Tzartos, V. Tsikaris, 1996, Biopolymers.

Multiple anchoring of myelopeptides on sequential oligopeptide carriers (SOC(n)): synthesis, conformation and studies in human leukemia cells.

V. Tsikaris, C. Sakarellos, M. Sakarellos-Daitsiotis, 2002, The journal of peptide research : official journal of the American Peptide Society.

Design, synthesis and catalytic activity of a serine protease synthetic model

A. Stavrakoudis, I. Demetropoulos, V. Tsikaris, 1997, Letters in Peptide Science.

Sequential oligopeptide carriers: from thermal polymerization to the construction of reconstituted antigenic and immunogenic conjugates

C. Sakarellos, M. Sakarellos-Daitsiotis, D. Krikorian, 2005, Journal of peptide science : an official publication of the European Peptide Society.

A major Sm epitope anchored to sequential oligopeptide carriers is a suitable antigenic substrate to detect anti-Sm antibodies.

H. Moutsopoulos, A. Tzioufas, P. Vlachoyiannopoulos, 1998, Journal of immunological methods.

Concept and design of a new class of sequential oligopeptide carriers (SOC) for covalent attachment of multiple antigenic peptides.

V. Tsikaris, C. Sakarellos, M. Sakarellos-Daitsiotis, 1998, Biopolymers.

Construction and application of a new class of sequential oligopeptide carriers (SOCn) for multiple anchoring of antigenic peptides--application to the acetylcholine receptor (AChR) main immunogenic region.

E. Vatzaki, S. Tzartos, V. Tsikaris, 1996, International Journal of Biological Macromolecules.

Use of sequential oligopeptide carriers (SOCn) in the design of potent Leishmania gp63 immunogenic peptides.

A. Tzinia, V. Tsikaris, C. Sakarellos, 1996, Peptide research.

Complementary peptide epitopes and anti-idiotypic antibodies in autoimmunity.

C. Sakarellos, M. Sakarellos-Daitsiotis, M. Cung, 2004, Protein and peptide letters.

A diepitopic sequential oligopeptide carrier (SOCn) as mimic of the Sm autoantigen: synthesis, conformation and biological assays

H. Moutsopoulos, P. Vlachoyiannopoulos, C. Alexopoulos, 2001, Journal of peptide science : an official publication of the European Peptide Society.

Changes in the c.d. spectra of calf thymus DNA induced by sequential polypeptides in trifluoroethanol solutions. Part II.

V. Tsikaris, C. Sakarellos, M. Sakarellos-Daitsiotis, 1991, International journal of biological macromolecules.

Circular dichroism studies on chromatin models. Interactions between DNA and sequential polypeptides containing arginine.

C. Sakarellos, M. Sakarellos-Daitsiotis, E. Panou-Pomonis, 1986, European Journal of Biochemistry.

Sequential polypeptides containing arginine as histone models: Synthesis and conformational studies

C. Sakarellos, M. Sakarellos-Daitsiotis, E. Panoy-Pomonis, 1986, Biopolymers.

A new method for the preparation of sequential polypeptides using matrix-controlled thermal polymerization.

C. Gilon, M. Goodman, C. Sakarellos, 1976, Journal of the American Chemical Society.

Sialic acid and sialyl‐lactose glyco‐conjugates: design, synthesis and binding assays to lectins and swine influenza H1N1 virus

U. Dietrich, A. Darji, S. Zevgiti, 2012, Journal of peptide science : an official publication of the European Peptide Society.

The position of the LysN epsilon H2-grafted antigens along the sequential oligopeptide carrier, Ac-(Aib-Lys-Aib-Gly)n (SOCn-II), influences the antibody recognition: application to the Sm main autoimmune epitope.

H. Moutsopoulos, P. Vlachoyiannopoulos, C. Alexopoulos, 2000, Biopolymers.

Sequential Oligopeptide Carriers (SOCn) for Producing Potent Antigens and Effective Immunogens

V. Tsikaris, C. Sakarellos, M. Sakarellos-Daitsiotis, 1997 .

Conformational requirements for molecular recognition of acetylcholine receptor main immunogenic region (MIR) analogues by monoclonal anti‐MIR antibody: A two‐dimensional nuclear magnetic resonance and molecular dynamics approach

E. Vatzaki, S. Tzartos, V. Tsikaris, 1993, Biopolymers.

Effect of synthetic peptides corresponding to residues 313–332 of the αIIb subunit on platelet activation and fibrinogen binding to αIIbβ3

J. Goudevenos, M. Elisaf, N. Biris, 2004 .

Relationship of the crystal and molecular structure of leucine-enkephalin trihydrate to that of morphine

A. Aubry, C. Sakarellos, M. Sakarellos-Daitsiotis, 1988 .

The presence of antibodies recognizing a peptide derived from the second conserved region of HIV-1 gp120 correlates with non-progressive HIV infection.

U. Dietrich, N. Veljkovic, S. Zevgiti, 2007, Current HIV research.

Circular dichroism studies on sequential polypeptides (Arg‐X‐Gly) when X = L‐Ala, Val, Leu, Ile, Nva, Nle in amphiphilic environments

V. Tsikaris, C. Sakarellos, M. Sakarellos-Daitsiotis, 2009 .

Collagen models as a probe in the decay of works of art: synthesis, conformation and immunological studies

S. Zevgiti, C. Sakarellos, M. Sakarellos-Daitsiotis, 2007, Journal of peptide science : an official publication of the European Peptide Society.

Palmitoylated peptide, being derived from the carboxyl-terminal sequence of the integrin αIIb cytoplasmic domain, inhibits talin binding to αIIbβ3

V. Moussis, V. Tsikaris, M. Sakarellos-Daitsiotis, 2014, Platelets.

The Ac–RGD–NH2 peptide as a probe of slow conformational exchange of short linear peptides in DMSO

A. Politou, A. Stavrakoudis, E. Mikros, 2003, Biopolymers.

Collagen and keratin polypeptide models for assessing the natural and artificial protein decay of organic materials

M. Sakarellos-Daitsiotis, E. Panou-Pomonis, E. Fotou, 2016, Journal of peptide science : an official publication of the European Peptide Society.

Effect of synthetic peptides corresponding to residues 313-332 of the alphaIIb subunit on platelet activation and fibrinogen binding to alphaIIbbeta3.

J. Goudevenos, M. Elisaf, N. Biris, 2004, European journal of biochemistry.

A three-residue cyclic scaffold of non-RGD containing peptide analogues as platelet aggregation inhibitors: design, synthesis, and structure--function relationships.

A. Stavrakoudis, V. Tsikaris, C. Sakarellos, 2000, Biopolymers.

CD studies of synthetic polypeptides as histone models: Poly(L‐Arg‐L‐Ile‐Gly), poly(L‐Arg‐L‐Nva‐Gly), and poly(L‐Arg‐L‐Nle‐Gly)

V. Tsikaris, C. Sakarellos, M. Sakarellos-Daitsiotis, 1988, Biopolymers.

17O NMR and FT‐IR study of the ionization state of peptides in aprotic solvents Application to Leu‐enkephalin

I. Gerothanassis, V. Tsikaris, B. Vitoux, 1992, FEBS letters.

Conformational and antigenic properties of SRYD-containing peptide analogues of Leishmania gp63 adhesion site

A. Tzinia, V. Tsikaris, C. Sakarellos, 1996, Letters in Peptide Science.

Conformational properties of the Arg-Leu-Gly tripeptide--DMSO--water clusters with the combined use of molecular dynamics and energy minimization studies.

I. Demetropoulos, V. Tsikaris, C. Sakarellos, 1995, Journal of biomolecular structure & dynamics.

NMR study on a SRYD-containing fibronectin-like sequence (250–257) of Leishmania gp63: contribution of residual water in the dimethyl sulfoxide solution structure

A. Tzinia, V. Tsikaris, C. Sakarellos, 1994 .

Structure of epitopes recognized by the antibodies to α(181–192) peptides of neuronal nicotinic acetylcholine receptors: extrapolation to the structure of acetylcholine-binding domain

R. Vanderesse, T. Tsouloufis, S. Tzartos, 2001, Journal of Neuroimmunology.

TR-NOE and MD studies ofLeishmania gp63 SRYD-containing sequences bound to anti-SRYD monoclonal antibody

A. Tzinia, V. Tsikaris, C. Sakarellos, 1997, Letters in Peptide Science.