Heekyung Chung

发表

Cyclin E and histone H3 levels are regulated by 5-fluorouracil in a DNA mismatch repair-dependent manner

J. Carethers, Heekyung Chung, Joy Chaudhry, 2010, Cancer biology & therapy.

A Gpr120 Selective Agonist Improves Insulin Resistance and Chronic Inflammation

R. Evans, S. Watkins, J. Olefsky, 2014, Nature Medicine.

Chronic fractalkine administration improves glucose tolerance and pancreatic endocrine function

Jong Bae Seo, A. Fanjul, J. Olefsky, 2018, The Journal of clinical investigation.

Increased Adipocyte O2 Consumption Triggers HIF-1α, Causing Inflammation and Insulin Resistance in Obesity

Jung-whan Kim, S. Watkins, J. Olefsky, 2014, Cell.

Reversed by Vitamin E Supplementation T Cells Is + Synapse Formation of CD4 Age-Associated Decline in Effective Immune

B. Huber, Dayong Wu, S. Meydani, 2007 .

Age-Associated Decline in Effective Immune Synapse Formation of CD4+ T Cells Is Reversed by Vitamin E Supplementation1

B. Huber, Dayong Wu, S. Meydani, 2007, The Journal of Immunology.

Vitamin E supplementation does not alter azoxymethane-induced colonic aberrant crypt foci formation in young or old mice.

J. Mason, B. Goldin, Dayong Wu, 2003, The Journal of nutrition.

LTB4 causes macrophage–mediated inflammation and directly induces insulin resistance in obesity

J. Olefsky, J. Ofrecio, M. Maris, 2015, Nature medicine.

Time-restricted feeding improves insulin resistance and hepatic steatosis in a mouse model of postmenopausal obesity.

Dorothy D. Sears, R. Patterson, N. Webster, 2016, Metabolism: clinical and experimental.

Omega-3 fatty acids reduce obesity-induced tumor progression independent of GPR120 in a mouse model of postmenopausal breast cancer

Dorothy D. Sears, J. Olefsky, N. Webster, 2014, Oncogene.

TGF- (cid:1) downregulates PTEN via activation of NF- (cid:2) B in pancreatic cancer cells

J. Carethers, Helen L Wu, Heekyung Chung, 2010 .

Microsatellite alterations at selected tetranucleotide repeats are associated with morphologies of colorectal neoplasias.

J. Carethers, Sun-Young Lee, B. Jung, 2010, Gastroenterology.

Effect of age on susceptibility to azoxymethane-induced colonic aberrant crypt foci formation in C57BL/6JNIA mice.

J. Mason, B. Goldin, Dayong Wu, 2003, The journals of gerontology. Series A, Biological sciences and medical sciences.

The CLK inhibitor SM08502 induces anti-tumor activity and reduces Wnt pathway gene expression in gastrointestinal cancer models.

S. Cha, C. Mak, C. Barroga, 2020, Cancer letters.

TGF-beta downregulates PTEN via activation of NF-kappaB in pancreatic cancer cells.

J. Carethers, Heekyung Chung, Helen L. Wu, 2010, American journal of physiology. Gastrointestinal and liver physiology.

Microsatellite Instability, EMAST, and Morphology Associations with T Cell Infiltration in Colorectal Neoplasia

J. Carethers, Sun-Young Lee, B. Jung, 2011, Digestive Diseases and Sciences.

Characterization of Distinct Subpopulations of Hepatic Macrophages in HFD/Obese Mice

R. Evans, J. Olefsky, J. Bogner-Strauss, 2014, Diabetes.

SM09419, a Novel, Small-Molecule CDC-like Kinase (CLK) Inhibitor, Demonstrates Strong Inhibition of the Wnt Signaling Pathway and Antitumor Effects in Tumor Protein p53 (TP53)-Mutant Acute Myeloid Leukemia Models

S. Cha, C. Mak, Heekyung Chung, 2019, Blood.

LTB4 promotes insulin resistance in obese mice by acting on macrophages, hepatocytes and myocytes

J. Olefsky, J. Ofrecio, M. Maris, 2015, Nature Medicine.

Flanking nucleotide specificity for DNA mismatch repair-deficient frameshifts within activin receptor 2 (ACVR2).

J. Carethers, Heekyung Chung, Joy Chaudhry, 2012, Mutation research.

Adipocyte SIRT1 knockout promotes PPARγ activity, adipogenesis and insulin sensitivity in chronic-HFD and obesity

D. Accili, J. Olefsky, L. Qiang, 2015, Molecular metabolism.

Mutation Rates of TGFBR2 and ACVR2 Coding Microsatellites in Human Cells with Defective DNA Mismatch Repair

J. Carethers, Jeffrey-K Lee, Heekyung Chung, 2008, PloS one.

Flanking Sequence Specificity Determines Coding Microsatellite Heteroduplex and Mutation Rates with Defective DNA Mismatch Repair (MMR)

J. Carethers, Heekyung Chung, B. Cabrera, 2010, Oncogene.

Mesalazine Reduces Mutations in Transforming Growth Factor β Receptor II and Activin Type II Receptor by Improvement of Replication Fidelity in Mononucleotide Repeats

C. Campregher, C. Gasche, J. Carethers, 2010, Clinical Cancer Research.

Leveraging model-based study designs and serial micro-sampling techniques to understand the oral pharmacokinetics of the potent LTB4 inhibitor, CP-105696, for mouse pharmacology studies

S. Bagrodia, M. Spilker, V. Fantin, 2017, Xenobiotica; the fate of foreign compounds in biological systems.

Pharmacokinetics of the potent LTB4 Inhibitor, CP-105696, in Male and Female Mice.

S. Bagrodia, M. Spilker, V. Fantin, 2016 .

Leveraging model-based study designs and serial micro-sampling techniques to understand

S. Bagrodia, M. Spilker, V. Fantin, 2016 .

Oxidative Stress Induces Nuclear-to-Cytosol Shift of hMSH3, a Potential Mechanism for EMAST in Colorectal Cancer Cells

J. Carethers, M. Iwaizumi, Heekyung Chung, 2012, PloS one.

SM09419, a Novel, Small-Molecule CDC-like Kinase (CLK) Inhibitor, Demonstrates Strong Inhibition of the Wnt Signaling Pathway and Antitumor Effects in Mantle Cell Lymphoma Models

S. Cha, C. Mak, Heekyung Chung, 2019, Blood.

LTB4 causes macrophage–mediated inflammation and directly induces insulin resistance in obesity

J. Olefsky, M. Maris, D. Oh, 2015, Nature Medicine.