S. Chu

发表

Biochemical pharmacology and toxicology of formycin alone and in combination with 2'-deoxycoformycin (pentostatin).

L. Ghoda, D. Dexter, P. Calabresi, 1983, Cancer treatment reports.

Action of uracil analogs on human immunodeficiency virus type 1 and its reverse transcriptase

Y. Cheng, G. Piras, S. Chu, 1995, Antimicrobial agents and chemotherapy.

Potentiation of 5-fluoro-2'-deoxyuridine antineoplastic activity by the uridine phosphorylase inhibitors benzylacyclouridine and benzyloxybenzylacyclouridine.

P. Calabresi, S. Chu, S. Cha, 1984, Cancer research.

Enhancement of 5-fluoro-2'-deoxyuridine antineoplastic activity by 5-benzyloxybenzyloxybenzylacyclouridine in a human colon carcinoma cell line.

E. Chu, S. Chu, Z. H. Chen, 1992, Cancer research.

Structure-activity relationship of ligands of the pyrimidine nucleoside phosphorylases.

S. Chu, S. Cha, J. G. Niedzwicki, 1983, Biochemical pharmacology.

5'-deoxy-5'-methylthioadenosine phosphorylase--V. Acycloadenosine derivatives as inhibitors of the enzyme.

C. Nakamura, T. Savarese, R. Parks, 1990, Biochemical pharmacology.

Inhibition of purine nucleoside phosphorylase by 9-(phosphonoalkyl)hypoxanthines.

C. Nakamura, R. Parks, J. Stoeckler, 1986, Biochemical pharmacology.

Resistance to 1-[(2-hydroxyethoxy)methyl]-6-(phenylthio)thymine derivatives is generated by mutations at multiple sites in the HIV-1 reverse transcriptase.

P. Boyer, S. Hughes, O. Weislow, 1995, Virology.

Sulfur and selenium compounds related to acetylcholine and choline. X. Acetylhionocholine.

H. Mautner, S. Chu, 1970, Journal of medicinal chemistry.

Inhibition of uridine phosphorylase from Escherichia coli by benzylacyclouridines.

K. Park, S. Chu, S. Cha, 1986, Biochemical pharmacology.

5-benzylacyclouridine and 5-benzyloxybenzylacyclouridine, potent inhibitors of uridine phosphorylase.

S. Chu, S. Cha, J. G. Niedzwicki, 1982, Biochemical pharmacology.

Effects of modifications in the pentose moiety and conformational changes on the binding of nucleoside ligands to uridine phosphorylase from Toxoplasma gondii.

R. Schinazi, C. K. Chu, S. Chu, 1996, Biochemical pharmacology.

Inhibitors of purine nucleoside phosphorylase, C(8) and C(5') substitutions.

R. Parks, J. Stoeckler, S. Chu, 1982, Biochemical pharmacology.

Pyrimidine acyclonucleosides, inhibitors of uridine phosphorylase.

S. Chu, S. Cha, J. G. Niedzwicki, 1981, Biochemical pharmacology.

5'-Deoxy-5'-methylthioadenosine phosphorylase--III. Role of the enzyme in the metabolism and action of 5'-halogenated adenosine analogs.

T. Savarese, R. Parks, S. Chu, 1985, Biochemical pharmacology.

Acycloadenosine Derivatives as Inhibitors of 5′-Deoxy-5′-Methylthioadenosine Phosphorylase (MesADo PASE)

C. Nakamura, T. Savarese, R. Parks, 1989 .

New analogues of benzylacyclouridines, specific and potent inhibitors of uridine phosphorylase from human and mouse livers.

S. Chu, S. Cha, F. Naguib, 1987, Biochemical pharmacology.

5′-Halogenated Formycins as Inhibitors of 5′-Deoxy-5′-methylthioadenosine Phosphorylase: Protection of Cells Against the Growth-Inhibitory Activity of 5′-Halogenated Adenosines

E. Chu, T. Savarese, S. Chu, 1986 .

Potential Antiradiation Agents. II. Selenium Analogs of 2-Aminoethylisothiouronium Hydrobromide and Related Compounds1-3

H. Mautner, S. Chu, 1962 .

Synthesis of racemic and enantiomerically pure 2′‐thia‐2′,3′‐dideoxycytidine as potential anti‐hepatitis B virus agents

S. Chu, Yung‐chi Cheng, B. Pan, 1997 .

Synthesis and cytotoxicity of 6-selenopurine arabinoside and related compounds.

C. Shiue, S. Chu, M. Chu, 1975, Journal of pharmaceutical sciences.

Phase I clinical and pharmacological studies of benzylacyclouridine, a uridine phosphorylase inhibitor.

E. Chu, J. Leffert, B. Burtness, 1998, Clinical cancer research : an official journal of the American Association for Cancer Research.

Synthesis of pyrimidine acyclonucleosides

S. Chu, H. Abrams, L. Ho, 1981 .

THE SYNTHESIS AND ANTINEOPLASTIC PROPERTIES OF SELENOGUANINE, SELENOCYTOSINE AND RELATED COMPOUNDS.

A. Sartorelli, H. Mautner, H G MAUTNER, 1963, Journal of medicinal chemistry.

Effect of the N-glycosidic bond conformation and modifications in the pentose moiety on the binding of nucleoside ligands to uridine phosphorylase.

J. Imbach, S. Chu, S. Cha, 1988, Molecular pharmacology.

Synthesis of aminomethyl and amino analogs of 5-benzylacyclouridine and 5-benzyloxybenzylacyclouridine

E. Chu, S. Chu, M. Chu, 1987 .

Potential Antiradiation Agents. β-Thioethylamino Derivatives of Nucleic Acid Constituents1,2

H. Mautner, S. Chu, 1961 .

Synthesis of 5-Halogeno-6-amino-2′-deoxyurldines and their Analogs as Potential Inhibitors of Thymidine Phosphorylase

E. Chu, S. Chu, B. Pan, 1998 .

Synthesis of pyrimidine acyclonucleosides

S. Chu, H. Abrams, L. Ho, 1981 .

Synthesis of some halogenated and disubstituted amino benzylacyclouridine derivatives

S. Chu, B. Pan, E. C. Rowe, 1992 .

Synthesis of enantiomers of 2′-aminomethyl-5-benzylacyclouridine (AM-BAU) and 2′-aminomethyl-5-benzyloxybenzylacyclouridine (AM-BBAU). Potent inhibitors of uridine phosphorylase

S. Chu, B. Pan, 1988 .

Synthesis of Aminomethyl and Amino Analogs of 5-Benzylacyclouridine and 5-Benzyloxybenzylacyclouridine.

E. Chu, S. Chu, M. Chu, 1988 .

Synthesis And Biological Activity Op Hydpdxymetflyl Analogs op 5-Benzylacyclouridine and 5-Benzyloxybenzylacycloaridine

S. Chu, F. Naguib, M. Chu, 1984 .

Benzylacyclouridine Enhances 5-Fluorouracil Cytotoxicity against Human Prostate Cancer Cell Lines

E. Chu, P. Calabresi, S. Chu, 1998, Pharmacology.

Synthesis of 5-Benzyl and 5-Benzyloxybenzyl 2,2′-Anhydrouridines and Related Nucleoside Analogs as Inhibitors of Uridine Phosphorylase

E. Chu, S. Chu, S. Cha, 1988 .

Synthesis of Enantiomers of 2′-Aminomethyl-5-benzylacyclouridine (AM-BAU) and 2′-Aminomethyl-5-benzyloxybenzylacyclouridine (AM-BBAU). Potent Inhibitors of Uridine Phosphorylase.

S. Chu, B. Pan, 1989 .

Synthesis of Some Halogenated and Disubstituted Amino Benzylacyclouridine Derivatives.

S. Chu, B. Pan, E. C. Rowe, 1992 .

Modulation of fudr host toxicity by two benzylacylouridine analogs

M. Wiemann, P. Calabresi, S. Chu, 1987 .

Synthesis of 5‐benzyl and 5‐benzyloxybenzyl‐3′‐azido‐2′,3′‐dideoxyuridine and their analogues as potential anti‐AIDS agents

S. Chu, B. Pan, E. C. Rowe, 1990 .

Synthesis of variants of 5‐benzylacyclouridine and 5‐benzyloxybenzylacyclouridine

E. Chu, S. Chu, M. Chu, 1986 .

Studies on the biochemical actions of 6-selenoguanine and 6-selenoguanosine.

R. Parks, K. Agarwal, A. Ross, 1973, Biochemical pharmacology.

Inhibition of nucleoside transport by nitrobenzylthioformycin analogs.

E. Acton, K. Ryan, R. Parks, 1990, Biochemical pharmacology.

Synthesis of 5-Benzyl and 5-Benzyloxybenzyl-3′-azido-2′,3′- dideoxyuridine and Their Analogues as Potential Anti-AIDS Agents

S. Chu, B. Pan, E. C. Rowe, 1991 .

Synthesis of Variants of 5-Benzylacyclouridine and 5-Benzyloxybenzylacyclouridine.

E. Chu, S. Chu, M. Chu, 1987 .

Synthesis and anti-hiv-1 activities of 6-arylthio and 6-arylselenoacyclonucleosides

G. Piras, S. Chu, G. Dutschman, 1994 .

Synthesis and biological activity of some 8-substituted seleno cyclic nucleotides and related compounds.

C. Shiue, S. Chu, M. Chu, 1974, Journal of medicinal chemistry.

A facile synthesis of 1-beta-D-arabinofuranosyl-2-seleno- and -4-selenouracil and related compounds.

C. Shiue, S. Chu, 1975, The Journal of organic chemistry.

A convenient one-step synthesis of 6-selenoxo-9-(β-D-ribofuranosyl)purine 3′,5′-cyclic phosphate and related compounds

C. Shiue, S. Chu, 1975 .

A new alkylation reagent for seleno- and thio-substituted nucleosides and related compounds.

C. Shiue, S. Chu, 1976, The Journal of organic chemistry.

The Aminolysis of Thioacyl and Selenoacyl Analogs

H. Mautner, S. Chu, W. Gunther, 2002 .

Biochemical pharmacology and toxicology of 8-azaadenosine alone and in combination with 2'-deoxycoformycin (pentostatin).

L. Ghoda, D. Dexter, P. Calabresi, 1982, Biochemical pharmacology.

Potential antitumor agents. 2. .alpha.- and .beta.-2'-Deoxy-6-selenoguanosine and related compounds

S. Chu, D. D. Davidson, 1972 .

Potential antitumor agents. Selenoguanosine and related compounds.

S. Chu, 1971, Journal of medicinal chemistry.

Inhibition of purine biosynthesis de novo in sarcoma 180 ascites cells by mercapto and seleno purine analogs.

E. Scholar, R. Parks, G. Crabtree, 1973, Biochemical pharmacology.

Synthesis of 5‐Halogeno‐6‐amino‐2′‐deoxyuridines and Their Analogues as Potential Inhibitors of Thymidine Phosphorylase.

E. Chu, S. Chu, B. Pan, 1999 .

A novel synthesis of 6-seleno-substituted nucleosides, nucleotides and cyclic nucleotides

C. Shiue, S. Chu, 1975 .

Studies of 2-Selenopyridine and Related Compounds1

H. Mautner, S. Chu, Calvin M. Lee, 1962 .

Analogs of Neuroeffectors. V. Neighboring-Group Effects in the Reactions of Esters, Thiolesters, and Selenolesters. The Hydrolysis and Aminolysis of Benzoylcholine, Benzoylthiolcholine, Benzoylselenolcholine, and of Their Dimethylamino Analogs1

H. Mautner, S. Chu, 1966 .

5’-methylthioadenosine phosphorylase as a chemotherapeutic target enzyme

D. Dexter, T. Savarese, P. Calabresi, 1982 .